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The Role of Food Supplements in Human Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: 15 September 2025 | Viewed by 1366

Special Issue Editors


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Guest Editor
Dipartimento di Scienza e Tecnologia del Farmaco, University of Turin, Via Pietro Giuria 9, 10125 Turin, Italy
Interests: type 2 diabetes; inflammation; insulin resistance; NLRP3 inflammasome
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Dipartimento di Scienza e Tecnologia del Farmaco, University of Turin, Via Pietro Giuria 9, 10125 Turin, Italy
Interests: NLRP3 inflammasome; inflammation; cancer; antiproliferative activity; herbal drugs

Special Issue Information

Dear Colleagues,

The European Food Safety Authority (EFSA) defines food supplements as concentrated sources of nutrients (i.e., mineral and vitamins) or other substances with a nutritional or physiological effect that are marketed in “dose” form (e.g., pills, tablets, capsules, liquids in measured doses). Food supplements are not intended to diagnose, treat, cure, or prevent any disease, but they can exert health benefits by supporting the physiological functions of the human body. Nowadays, more and more people are using food supplements for their wellness; consumers are drawn as a result of both their easy accessibility and the increasing focus on personal health. However, evidence about the specific mechanisms underlying their beneficial effects is lacking and requires further investigation.

This Special Issue will focus on the latest advances regarding food supplements. Particularly welcome will be high-quality evidence on the following topics: (i) the mechanisms that could explain the beneficial effects exerted by food supplements, clarifying their potential role in human health or in conditions affected by unhealthy diets and lifestyles, such as dyslipidemia, diabetes, obesity, or inflammatory disorders; and (ii) the interaction between dietary supplements and conventional drugs.

This Special Issue of Nutrients, entitled “The Role of Food Supplements in Human Health”, welcomes original research and review articles on the more recent literature concerning this topic.

Dr. Elisa Benetti
Dr. Valentina Boscaro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dietary supplements
  • nutraceuticals
  • vitamins
  • minerals
  • botanicals
  • herbs
  • human health
  • inflammation
  • diseases

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Published Papers (1 paper)

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Review

28 pages, 3873 KiB  
Review
Management of Fibromyalgia: Novel Nutraceutical Therapies Beyond Traditional Pharmaceuticals
by Antonella Antonelli, Marzia Bianchi, Elizabeth Jane Fear, Luca Giorgi and Luigia Rossi
Nutrients 2025, 17(3), 530; https://doi.org/10.3390/nu17030530 - 31 Jan 2025
Viewed by 1163
Abstract
The pathophysiology of fibromyalgia, a condition that causes chronic pain throughout the body, involves abnormal pain signaling, genetic predispositions, and abnormal neuroendocrine function, significantly impairing quality of life. Fibromyalgia is commonly characterized by musculoskeletal pain, chronic fatigue, and severe sleep alterations. Changes in [...] Read more.
The pathophysiology of fibromyalgia, a condition that causes chronic pain throughout the body, involves abnormal pain signaling, genetic predispositions, and abnormal neuroendocrine function, significantly impairing quality of life. Fibromyalgia is commonly characterized by musculoskeletal pain, chronic fatigue, and severe sleep alterations. Changes in the central processing of sensory input and defects in endogenous pain inhibition could be the basis of enhanced and persistent pain sensitivity in individuals with fibromyalgia. The term central sensitivity syndrome was chosen as an umbrella term for fibromyalgia and related illnesses, including myalgic encephalomyelitis/chronic fatigue syndrome, migraine, and irritable bowel syndrome. Given the substantial impact of fibromyalgia on health, there is a need for new prevention and treatment strategies, particularly those involving bioavailable nutraceuticals and/or phytochemicals. This approach is particularly important considering the adverse effects of current fibromyalgia pharmaceutical treatments, such as antidepressants and anticonvulsants, which can lead to physical dependence and tolerance. Natural products have recently been considered for the design of innovative analgesics and antinociceptive agents to manage fibromyalgia pain. Polyphenols show promise in the management of neuropathic pain and fibromyalgia, especially considering how anti-inflammatory treatments, including corticosteroids and nonsteroidal medical drugs, are effective only when inflammatory processes coexist and are not recommended as the primary treatment for fibromyalgia. Full article
(This article belongs to the Special Issue The Role of Food Supplements in Human Health)
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