Anti-Infective Agents
A special issue of Pharmaceuticals (ISSN 1424-8247).
Deadline for manuscript submissions: closed (31 March 2010) | Viewed by 68001
Special Issue Editor
Interests: natural products; antiinfectives; anticancer agents; NMR spectroscopy; marine ecology; synthesis of natural products; biosynthesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Despite the tremendous progress in human medicine, infectious diseases represent one of the greatest challenges to mankind in the 21st century. According to WHO, infectious diseases account for nearly a third of global deaths. AIDS, malaria, tuberculosis and respiratory infections were among the top eight leading causes of death in 2004. The burden of infectious diseases falls particularly on the less developed countries due to the relative unavailability of medicines and the emergence of widespread drug resistance. In developing countries, a high infectious disease burden commonly co-exists with rapid emergence and spread of microbial resistance. The growing threat of emerging diseases such as SARS and influenza A (H1N1) has served as a wake-up call to public health services, pharmaceutical industry and academia.
Because the evolution of drug resistance is likely to compromise every drug in time, research on new anti-infective agents must be continued and all possible strategies should be explored. Besides small molecules from medicinal chemistry, natural products are still major sources of innovative therapeutic agents for various conditions, including infectious diseases.
This special issue welcomes research articles and comprehensive reviews addressing the discovery and/or development of anti-infective agents.
Prof. Dr. Paul Cos
Prof. Dr. Mark Hamann
Guest Editor
Keywords
- anti-infectives
- biofilm
- bacterial virulence
- oxidative stress
- antibacterial
- antifungal
- antiparasitic
- antiviral
- screening
- small molecules
- natural products
Related Special Issue
- Anti-Infective Agents in Molecules (5 articles)