Advanced Nanomaterials and Drug Delivery Systems for Wound Healing and Antimicrobial Therapy

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 74

Special Issue Editors


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Guest Editor
Department of Chemistry, University of Fort Hare, Alice Campus, Alice 5700, South Africa
Interests: polymer-based materials; wound dressings; drug delivery systems; nanocarriers; drug discovery and design; organic synthesis of drug molecules (antimalarials, antimicrobials, anticancer)
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Guest Editor
Department of Chemical Sciences, University of Johannesburg, P.O. Box 17011 Doornfontein, Johannesburg 2028, South Africa
Interests: heterocycles; biological activities; natural products; drug discovery

Special Issue Information

Dear Colleagues,

The treatment of microbial infections and wound healing are two challenging aspects of biomedicine. Microbes can evolve, becoming resistant to drugs and difficult to treat. Drug resistance and the presence of only a few new antimicrobial medicines in the clinical pipeline reveal an urgent need for more research in developing new and effective antimicrobial therapeutics. On the other hand, wound healing is also impeded by microbial infections, resulting in inflammation, damaged tissue, delayed healing, and, in some cases, biofilm formation. Multidrug‐resistant organisms are visible in acute and chronic wound infections. The few available therapeutic options further compromise the current efforts in treating infected wounds.

Nanotherapeutics has evolved as a promising option for preventing, treating, and detecting microbial infections. Some of their unique features include the targeted delivery of the loaded/encapsulated therapeutic agents to the target sites, prolonged controlled release of bioactive molecules,  excellent antimicrobial properties, the promotion of angiogenesis, minimized scarring in the wound healing process, multiple pathways to combat microbes and overcome microbial resistance mechanisms, evading existing resistance mechanisms, and their ability to be tailored for optimal therapeutic outcomes.

This Special Issue aims to highlight recent advancements in the development of advanced nanostructured materials/systems for treating microbial infections and wound healing. Original research articles and reviews are welcome. 

Prof. Dr. Blessing Atim Aderibigbe
Dr. Marthe Carine D. Fotsing
Guest Editors

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Keywords

  • nanotherapeutics
  • wound dressings
  • nanoparticles
  • nanometals
  • antimicrobial drugs
  • debridement
  • skin regeneration
  • controlled delivery systems
  • targeted delivery systems
  • bioactive 3D scaffolds
  • scar
  • nanotechnology
  • drug delivery
  • chronic wounds
  • acute wounds
  • microbial infections
  • HIV
  • viral infections
  • fungal infections
  • bacterial infections
  • drug resistance
  • nanocarriers

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Published Papers

This special issue is now open for submission.
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