Plant-Based Bioactive Substances Identification, Extraction, and Application
A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 8408
Special Issue Editors
Interests: organic synthesis; natural products; theoretical calculation; spectrometric methods; structure identification; pesticide science
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Natural products of vegetable origin, particularly secondary metabolites, are produced by plants to protect them from abiotic and biotic stresses. The structural variety of compounds is extraordinary and represents the richness of biological diversity in plant chemical ecology, in addition to plant–plant, plant–microorganism, and plant–animal interactions. Investigating this diversity of organic compounds is a source of inspiration for application in the food industry, medicinal chemistry, biotechnology, and agrochemistry. Obtaining bioactive compounds involves the extraction, isolation, structural elucidation, and evaluation of biological activity. The techniques commonly used in structural elucidation are nuclear magnetic resonance (NMR) spectroscopy associated with DFT computational calculations, mass spectrometry, and infrared spectroscopy. This Special Issue of Plants will highlight bioactive substances of plant origin, with a specific focus on extraction, identification, an evaluation of biological activity, and application.
Prof. Dr. Elson S. Alvarenga
Prof. Dr. Wei Li
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- bioassay
- NMR
- biological evaluation
- theoretical calculation
- DFT
- natural products
- mass spectrometry
- infrared
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Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: LC-MS Identification of Daphnane Diterpenoids from Wikstroemia indica
Authors: Prof. Dr. Wei Li
Affiliation: Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan
Abstract: Daphnane diterpenoids, known for their potential in anti-HIV and anticancer drug development, are characteristic metabolites found in plants of the Thymelaeaceae family. Wikstroemia indica (L.) C. A. Mey., a plant species distributed in southeastern China and traditionally used for treating bronchitis, hepatitis, and cancer, has attracted attention in our ongoing study focused on the discovery of bioactive daphnane diterpenoids from Thymelaeaceae plants. In this study, liquid chromatography coupled with electrospray ionization mass spectrometry (LC-ESI-MS) was employed to analyze the chemical constituents of W. indica. Through meticulous analysis of information, including molecular formula of precursor ion, retention time, along with the interpretation of characteristic MS/MS fragmentation patterns, and validation via isolation and nuclear magnetic resonance (NMR) spectroscopic analyses, 21 daphnane diterpenoids were successfully identified in W. indica. This study unveils the presence of daphnane diterpenoids in W. indica for the first time, offering valuable insights into their distribution among plants and potential applications in drug discovery.