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Toxics
Special Issues
Innovative Toxicological Tools for Food and Environmental Safety
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Innovative Toxicological Tools for Food and Environmental Safety

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Novel Methods in Toxicology Research".

Deadline for manuscript submissions: closed (24 September 2023) | Viewed by 5751

Special Issue Editors

Dr. Yizhong Shen

E-Mail Website
Guest Editor
School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China
Interests: toxicological techniques; environmental analytical chemistry; food safety analysis and risk assessment; molecular spectrum technology; exposome; point-of-care testing
Special Issues, Collections and Topics in MDPI journals
Dr. Yong Li

E-Mail Website
Guest Editor
Department of Life Science and Technology, Central South University of Forestry and Technology, Changsha, China
Interests: ecotoxicology; emerging contaminants; environmental analytical chemistry; environmental pollution; restoration ecology; risk assessment; toxicological techniques
Dr. Xin Liu

E-Mail Website
Guest Editor
School of Food Science and Engineering, Wuhan Polytechnic University, Wuhan, China
Interests: food toxicology; toxicological evaluation; metabonomics; food safety risk assessment; exposome; environmental chemistry; environmental epidemiology; LC-MS analysis for pollutants; human health risk assessment

Special Issue Information

Dear Colleagues,

New and emerging pollutants present a global challenge with potentially serious threats to food and environmental safety. An assessment of whether food or the environment will experience deleterious effects before or after the risk occurs is urgent. Efficient toxicological tools are needed that can issue early warnings of potential risks posed to food and the environment. This Special Issue focuses on using innovative toxicological tools to explore the toxicological effects of new or potential risks in food and environment-related matrices, such as in metabonomic and lipidomic matrices, and the integration of multi-omics, molecular spectra, mass spectra, electrochemistry, chromatography, nanotechnology, etc. Original research papers, reviews and short communications are all welcome.

Dr. Yizhong Shen
Dr. Yong Li
Dr. Xin Liu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ecotoxicology
  • emerging contaminants
  • environmental analytical chemistry
  • environmental pollution
  • restoration ecology
  • risk assessment
  • toxicological techniques

Published Papers (3 papers)

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Research

19 pages, 1696 KiB  
Article
Elemental Profile in Chicken Egg Components and Associated Human Health Risk Assessment
by Cezara Voica, Gabriela Cristea, Andreea Maria Iordache, Carmen Roba and Victor Curean
Toxics 2023, 11(11), 900; https://doi.org/10.3390/toxics11110900 - 3 Nov 2023
Cited by 2 | Viewed by 1631
Abstract
Egg is a food product of high nutritional quality, extensively consumed worldwide. The objectives of this study were the determination of the elemental profile in eggs (egg white, yolk, and eggshell), the estimation of the non-carcinogenic health risk associated with the presence of [...] Read more.
Egg is a food product of high nutritional quality, extensively consumed worldwide. The objectives of this study were the determination of the elemental profile in eggs (egg white, yolk, and eggshell), the estimation of the non-carcinogenic health risk associated with the presence of heavy metals in investigated egg samples, and the development of statistical models to identify the best predictors for the differentiation of egg components. The assessments were carried out in a total set of 210 samples, comprising home-produced and commercial eggs, using inductively coupled plasma mass spectrometry. The results suggested measurable differences amongst hen eggs coming from different husbandry systems. The statistical models employed in this study identified several elemental markers that can be used for discriminating between market and local producer samples. The non-carcinogenic risk related to the consumption of the analyzed egg samples was generally in the safe range for the consumers, below the maximum permitted levels set by Romanian and European legislation. Food contamination is a public health problem worldwide, and the risk associated with exposure to trace metals from food products has aroused widespread concern in human health, so assessing the heavy metal content in food products is mandatory to evaluate the health risk. Full article
(This article belongs to the Special Issue Innovative Toxicological Tools for Food and Environmental Safety)
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11 pages, 3461 KiB  
Article
Simulation and Characterization of Nanoplastic Dissolution under Different Food Consumption Scenarios
by Ying Wang, Zhongtang Wang, Xin Lu, Hongyan Zhang and Zhenzhen Jia
Toxics 2023, 11(7), 550; https://doi.org/10.3390/toxics11070550 - 23 Jun 2023
Cited by 1 | Viewed by 1565
Abstract
Understanding of the potential leaching of plastic particles, particularly nanoplastics (NPs), from food packaging is crucial in assessing the safety of the packaging materials. Therefore, the objective of this study was to investigate potential exposure risks by simulating the release of NPs from [...] Read more.
Understanding of the potential leaching of plastic particles, particularly nanoplastics (NPs), from food packaging is crucial in assessing the safety of the packaging materials. Therefore, the objective of this study was to investigate potential exposure risks by simulating the release of NPs from various plastic packaging materials, including polypropylene (PP), general casting polypropylene (GCPP) or metalized casting polypropylene (MCPP), polyethylene (PE), polyethylene terephthalate (PET), and polyphenylene sulfone (PPSU), under corresponding food consumption scenarios. Surface-enhanced Raman scattering (SERS) and scanning electron microscopy (SEM) were utilized to identify and characterize the NPs leached from plastic packaging. The presence of separated NPs was observed in PP groups subjected to 100 °C hot water, GCPP plastic sterilized at a high temperature (121 °C), and PE plastic soaked in 100 °C hot water, exhibited a distorted morphology and susceptibility to aggregation. The findings suggest that the frequent consumption of takeaway food, hot beverages served in disposable paper cups, and foods packaged with GCPP materials may elevate the risk of ingestion of NPs. This reminds us that food packaging can serve as an important avenue for human exposure to NPs, and the results can offer valuable insights for food safety management and the development of food packaging materials. Full article
(This article belongs to the Special Issue Innovative Toxicological Tools for Food and Environmental Safety)
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13 pages, 2648 KiB  
Article
Rapid Simultaneous Determination of Three Synthetic Cannabinoids in Urine and Plasma of Rats Using Ultra-High Performance Liquid Chromatography Tandem Mass Spectrometry
by Xing Ke, Yimei Tian, Dandan He, Pengqian Mu, Xuzhi Wan, Lange Zhang, Wei Jia, Qiao Wang, Yilei Fan and Yu Zhang
Toxics 2022, 10(10), 619; https://doi.org/10.3390/toxics10100619 - 18 Oct 2022
Cited by 1 | Viewed by 1629
Abstract
Synthetic cannabinoids, a class of psychoactive compounds, are controlled as new psychoactive substances (NPSs) identified by the early warning system (EWS) of the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). At present, several new synthetic cannabinoids have appeared in the illegal [...] Read more.
Synthetic cannabinoids, a class of psychoactive compounds, are controlled as new psychoactive substances (NPSs) identified by the early warning system (EWS) of the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). At present, several new synthetic cannabinoids have appeared in the illegal drug market, including 4-methylnaphthalen-1-yl-(1-pentylindol-3-yl) methanone (JWH-122), methyl (1-(5-fluoropentyl)-1H-indazole-3-carbonyl)-L-valinate (5F-AMB), and methyl 2-(1-(4-fluorobenzyl)-1Hindazole-3-carboxamido)-3-methylbutanoate (AMB-FUBINACA). A convenient, rapid, and highly sensitive analytical method was developed to determine three synthetic cannabinoids in rat plasma and urine. The liquid chromatography tandem mass spectrometry (LC-MS/MS) method was optimized and validated to analyze the three synthetic cannabinoids in rat plasma and urine. The method identified intra-assay precision (1.3–9.0% and 2.8–6.7%), inter-assay precision (3.0–8.6% and 3.9–8.8%), limits of detection (0.003–0.004 ng/mL and 0.00125–0.002 ng/mL) and quantification (0.012–0.016 ng/mL and 0.003–0.005 ng/mL), recovery (95.4–106.8% and 92.0–106.8%) for rat plasma and urine, and the matrix effect (93.4–118.0%) for rat urine, and the correlation coefficients were above 0.99 in the linear range. The established LC-MS/MS method was successfully used to simultaneously detect the JWH-122 and 5F-AMB in rat plasma and JWH-122, 5F-AMB, and AMB-FUBINACA in rat urine. The present study provides methodological support for internal exposure assessment of three synthetic cannabinoids and promotes the quantitative analysis and technical supervision of synthetic cannabinoids. Full article
(This article belongs to the Special Issue Innovative Toxicological Tools for Food and Environmental Safety)
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