Small Animal Gastrointestinal Diseases: Challenges and Advances

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Internal Medicine".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 2286

Special Issue Editor


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Guest Editor
Veterinary Clinical Medicine Department, University of Pisa, Pisa, Italy
Interests: small animal gastroenterology; oncology; internal medicine; clinical pathology
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Special Issue Information

Dear Colleagues,

Over the past 10 years, research in gastroenterology and hepatology has made much progress. It also has highlighted research aspects that changed how we approach both the diagnostic and therapeutical processes of liver and intestinal diseases, especially those associated with microbiota and metabolomics. In addition, some studies have shown important pathogenetic associations between the organs of the digestive system and other organs, such as the kidneys, pancreas, and endocrine glands.

This Special Issue aims to provide an update on the new knowledge for the clinical management of the digestive diseases of dogs and cats.

Original research articles, reviews, and communications are welcome. Research areas may include acute and chronic enteropathies, acute and chronic pancreatitis, hepatitis, and biliary tract disease in all aspects of diagnostics and therapeutics. Studies on innovative diagnostic techniques and biomarkers will be particularly appreciated. Hopefully, this Special Issue will further stimulate collaboration between scientists engaged in all aspects of this field of research.

Dr. Veronica Marchetti
Guest Editor

Manuscript Submission Information

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Keywords

  • pancreatitis
  • enteropathy
  • hepatitis
  • cholecystitis
  • microbiota
  • metabolomic
  • biomarkers

Published Papers (2 papers)

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Research

11 pages, 282 KiB  
Article
Clinical and Diagnostic Findings in Dogs Infected with Trichuris vulpis: A Retrospective Study
by Mario Cervone, Marine Hugonnard, Gilles Bourdoiseau, Luc Chabanne, Emilie Krafft and Jean-Luc Cadoré
Vet. Sci. 2024, 11(7), 306; https://doi.org/10.3390/vetsci11070306 - 10 Jul 2024
Viewed by 723
Abstract
Trichuris vulpis is a parasite of the large intestine of canids and has a global distribution. Despite its well-established epidemiology, the question of its pathogenicity in dogs remains debated. It has been suggested that younger age and concurrent infection with Ancylostoma caninum may [...] Read more.
Trichuris vulpis is a parasite of the large intestine of canids and has a global distribution. Despite its well-established epidemiology, the question of its pathogenicity in dogs remains debated. It has been suggested that younger age and concurrent infection with Ancylostoma caninum may be responsible for more severe clinical presentations. This retrospective study aimed to describe the clinical and diagnostic features of T. vulpis-infected dogs and to compare these findings with dogs infected with both T. vulpis and other intestinal parasites (poly-infected dogs). Forty-five dogs were included, with twenty-five being solely infected by T. vulpis and twenty poly-infected dogs. Only weight loss was more frequent (p = 0.006) in poly-infected dogs compared to T. vulpis mono-infected dogs. No significant differences were observed in laboratory abnormalities between mono-infected and poly-infected dogs. Only diarrhea was more frequent (p = 0.007) in younger dogs compared to adults. The egg shedding pattern was significantly higher (p = 0.04) among adult dogs compared to young ones, and there was a significant positive correlation between egg shedding and age (r = 0.41; p = 0.005). These findings suggest that T. vulpis might be responsible for both clinical signs and laboratory abnormalities in dogs, irrespective of the host’s age and the presence of other intestinal parasites. Full article
(This article belongs to the Special Issue Small Animal Gastrointestinal Diseases: Challenges and Advances)
11 pages, 251 KiB  
Article
Retrospective Study of 222 Dogs Suffering from Food-Responsive Enteropathy—Correlation with Clinical Variables, Diet and Breed
by Alessia Candellone, Gaia Raviri, Vittorio Saettone, Martine Didier, Giacomo Rossi, Andrea Marchegiani, Alessandra Gavazza, Alessandro Di Cerbo and Matteo Cerquetella
Vet. Sci. 2024, 11(7), 294; https://doi.org/10.3390/vetsci11070294 - 1 Jul 2024
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Abstract
Food-responsive enteropathy (FRE) is the most frequent form of canine chronic inflammatory enteropathy (CIE). It can be diagnosed if, after excluding known causes of diarrhea, clinical signs resolve or significantly improve after an appropriate dietary trial. No universal diet can resolve the clinical [...] Read more.
Food-responsive enteropathy (FRE) is the most frequent form of canine chronic inflammatory enteropathy (CIE). It can be diagnosed if, after excluding known causes of diarrhea, clinical signs resolve or significantly improve after an appropriate dietary trial. No universal diet can resolve the clinical signs in every case of FRE, as genetic predisposition and environment (e.g., the possible role of the diet feed before the disease onset) are suggested as possible players. The study aimed to retrospectively evaluate the possible correlations between disease, diet, and breed in a large cohort of dogs (n = 222) suffering from FRE. Throughout the study, dogs differed based on dietary options: commercial diet group, homemade diet group, and mixed diet group. Diet, breed, age, body weight, body condition score (BCS), fecal score (FS), canine chronic enteropathy activity index (CCECAI), and selected clinical signs were variably evaluated at T0 and at final time (FT—based on response to the diet[s], but between 30 and 60 days). Significant differences between T0 and FT were found regarding FS, BCS, and CCECAI, as well as between age, BCS, and CCECAI at FT with the FS at FT. The CCECAI at FT was significantly directly correlated only with the shift from a mixed to a homemade diet. Finally, the multiple linear regression analysis between the covariables of different breeds versus clinical response to the dietary trials did not highlight any difference except for the passage from commercial to mixed diet in a specific subgroup of breeds. The present study reports the clinical progression in 222 dogs suffering from FRE, and it could represent a reference for the variables investigated, considering the large number of patients included. Full article
(This article belongs to the Special Issue Small Animal Gastrointestinal Diseases: Challenges and Advances)
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