Table of Contents
Int. J. Mol. Sci., Volume 19, Issue 3 (March 2018)
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Cover Story (view full-size image) Tyrosinase is the key enzyme of melanin production in melanosomes, which are transferred from [...] Read more. Tyrosinase is the key enzyme of melanin production in melanosomes, which are transferred from epidermal melanocytes to keratinocytes. Inhibitors of tyrosinase are of great clinical interest for the treatment of hyperpigmentation. However, most inhibitors described in the literature were only tested on mushroom tyrosinase and thus lack clinical efficacy. In the present study, a recombinant soluble human tyrosinase was used to analyze the structure–activity relationships of thiazolyl resorcinols, a novel class of tyrosinase inhibitor. View the paper here.