2014 March - 19 articles
Growing concern for the environment, increasing stringent standards for the release of chemicals into the environment and economic competiveness have led to more environmentally friendly approaches that have resulted in greater pollution prevention v...
Flotation constitutes a gravity separation process, which originated from the minerals processing field. However, it has, nowadays, found several other applications, as for example in the wastewater treatment field. Concerning the necessary bubble ge...
Fast process development, flexible production and the utilization of advanced process conditions are the main goals of modular and continuous small-scale plants (MCSPs). A configurable layout of the modules and the use of predefined equipment enable...
Many products from the fine chemicals and pharmaceuticals industries are currently manufactured batch-wise in multi-product plants. However, this processing scheme suffers from severe drawbacks, such as a high specific energy demand, cleaning costs a...
The goal of the present study is to integrate different datasets in cell biology to derive additional quantitative information about a gene or protein of interest within a single cell using computational simulations. We propose a novel prototype cell...
The editors of Processes would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2013. [...]
Dividing-wall columns (DWCs) have significant potential as energy-efficient processes for the separation of multicomponent mixtures. However, in addition to an efficient steady state design, dynamics and control also play a major part for the success...
The absorption and chemisorption of small bubbles with N2 or CO2 were investigated experimentally in aqueous and alkaline solutions. Different bubble sizes were studied ranging from 0.1 to 2.5 mm in alkaline concentrations of 0.1 mM to 1 M NaOH. The...
Tissue engineering may constitute a promising alternative to current strategies in ligament repair, providing that suitable scaffolds and culture conditions are proposed. The objective of the present contribution is to present the design and instrume...
The use of metal-assisted HF chemical etching as a convenient technique to produce a few microns thick porous layer in silicon microchannels was demonstrated. Gas phase selective oxidation of rosalva to its aldehyde (costenal) was performed in glass/...
This article summarizes selected examples of intra- and intermolecular photodecarboxylations involving phthalimides in a commercially available dwell device. Compared to batch conditions in a larger chamber reactor, the investigated transformations i...
The adoption of detailed mechanisms for chemical kinetics often poses two types of severe challenges: First, the number of degrees of freedom is large; and second, the dynamics is characterized by widely disparate time scales. As a result, reactive f...
In this study, a hybrid multi-scale model has been developed for a continuous fluid bed wet granulation process by dynamically coupling computational fluid dynamics (CFD) with a discrete element model (DEM) and population balance model (PBM). In this...
To mimic in vivo vibration of vocal fold cells, we studied the controllability and range of frequency, acceleration, duration, and shear stress in a new bioreactor attachment. The custom multiwell disc appliance fits into a commercially built rheomet...
A controlled radical polymerization process using the Reversible Addition-Fragmentation Chain Transfer (RAFT) approach was scaled up by a factor of 100 from a small laboratory scale of 5 mL to a preparative scale of 500 mL, using batch and continuou...
Radial flow perfusion of cell-seeded hollow cylindrical porous scaffolds may overcome the transport limitations of pure diffusion and direct axial perfusion in the realization of bioengineered substitutes of failing or missing tissues. Little has bee...
The traditional use of TiO2 powder as a photocatalyst for degradation of organic compounds has several post-degradation treatment problems, such as filtration, precipitation, etc. A novel method was developed to immobilize TiO2 to minimize/eliminat...
Continuous flow reactors (CFRs) are an emerging technology that offer several advantages over traditional batch synthesis methods, including more efficient mixing schemes, rapid heat transfer, and increased user safety. Of particular interest to the...
A novel multi-axial bioreactor was designed and developed to deliver combinations of the following dynamic mechanical stimulation conditions: hydrostatic pressure, pulsatile perfusion flow and uniaxial compression in order to mimic in vivo conditions...
