Heterocyclic Chemistry and Catalysis

A special issue of Catalysts (ISSN 2073-4344). This special issue belongs to the section "Catalysis in Organic and Polymer Chemistry".

Deadline for manuscript submissions: closed (31 January 2020) | Viewed by 7158

Special Issue Editor


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Guest Editor
Institut de Chimie Organique et Analytique (ICOA), Université d’Orléans, UMR-CNRS 7311, BP 6759, Rue de Chartres, 45067 Orléans, France
Interests: methodological studies in heterocyclic chemistry; formation of C–C, C–N, C–O, and C–S bonds; synthesis or hemisynthesis of heterocyclic or bioactive molecules or natural products; environmentally friendly methods
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Special Issue Information

Dear Colleagues,

Heterocycles can be found in all kinds of organic compounds of interest in biology, agro chemistry pharmacology, medicine, and materials science. In the last few decade, the use of catalytic processes mainly by transition-metal complexes has considerably impacted modern organic synthesis methodologies, but many improvements are still possible in terms of selectivity or even enantioselectivity via the development of new ligands or the study of the catalytic effect of other metals to carry out the same or new chemical transformations. In addition, the attention paid to environmentally friendly methods in terms of the quantities of catalysts, ligands, and solvents is currently indispensable.

This Special Issue on Heterocyclic Chemistry and Catalysis will focus on new advances in catalytic processes applied to heterocyclic compounds. In doing so, we placed specific emphasis on original research papers and short reviews of the synthesis of biologically active compounds using transition metals catalysts, the identification of new catalysts, the synthesis of new ligands allowing selectivity or enantioselectivity of the synthetic pathway, the activity and stability of catalysts under turnover conditions, news materials, and all the improvements in the catalytic processes.

Prof. Dr. Sabine Berteina-Raboin
Guest Editor

Manuscript Submission Information

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Keywords

  • heterocyclic methodologies
  • catalytic processes
  • new catalysts
  • bioactives molecules
  • synthetic or hemi-synthetic pathways
  • enrironmentally friendly methods

Published Papers (2 papers)

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Research

11 pages, 2022 KiB  
Article
Eucalyptol as a Bio-Based Solvent for Buchwald-Hartwig Reaction on O,S,N-Heterocycles
by Joana F. Campos and Sabine Berteina-Raboin
Catalysts 2019, 9(10), 840; https://doi.org/10.3390/catal9100840 - 10 Oct 2019
Cited by 13 | Viewed by 3764
Abstract
We report here the use of eucalyptol as a bio-based solvent for the Buchwald–Hartwig reaction on O,S,N-heterocycles. These heterocycles containing oxygen, sulfur and nitrogen were chosen as targets or as starting materials. Once again, eucalyptol demonstrated to be a possible sustainable alternative to [...] Read more.
We report here the use of eucalyptol as a bio-based solvent for the Buchwald–Hartwig reaction on O,S,N-heterocycles. These heterocycles containing oxygen, sulfur and nitrogen were chosen as targets or as starting materials. Once again, eucalyptol demonstrated to be a possible sustainable alternative to common solvents. Full article
(This article belongs to the Special Issue Heterocyclic Chemistry and Catalysis)
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22 pages, 7968 KiB  
Article
Synthesis of Pyrazolo-Fused 4-Azafluorenones in an Ionic Liquid. Mechanistic Insights by Joint Studies Using DFT Analysis and Mass Spectrometry
by Efraín Polo, Valentina Arce-Parada, Xaviera A. López-Cortés, Jesús Sánchez-Márquez, Alejandro Morales-Bayuelo, Oscar Forero-Doria and Margarita Gutiérrez
Catalysts 2019, 9(10), 820; https://doi.org/10.3390/catal9100820 - 29 Sep 2019
Cited by 6 | Viewed by 2733
Abstract
A series of pyrazolo-fused 4-azafluorenones (indeno[1,2-b]pyrazolo[4,3-e]pyridines, IPP) were synthesized via the three-component reaction between arylaldehydes, 3-methyl-1H-pyrazol-5-amine and 1,3-indanedione in an ionic liquid as a catalyst at room temperature. The applied synthetic route has the advantages of easy work-up under mild reaction [...] Read more.
A series of pyrazolo-fused 4-azafluorenones (indeno[1,2-b]pyrazolo[4,3-e]pyridines, IPP) were synthesized via the three-component reaction between arylaldehydes, 3-methyl-1H-pyrazol-5-amine and 1,3-indanedione in an ionic liquid as a catalyst at room temperature. The applied synthetic route has the advantages of easy work-up under mild reaction conditions presenting moderate yields and an environmentally benign procedure. A theoretical study based on conceptual-density functional theory has been done, bond reactivity indices have been calculated and an electrophilic and nucleophilic character of localized orbitals has been determined to analyze the possible electronic mechanisms. Full article
(This article belongs to the Special Issue Heterocyclic Chemistry and Catalysis)
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