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Molecules, Volume 30, Issue 4

February-2 2025 - 218 articles

Cover Story: Many pathogenic bacteria can form biofilms, where cells become attached to a surface and are entrapped in a matrix of exopolysaccharides, extracellular DNA, and proteins. Such sessile bacteria are extremely resistant to antibiotics and to the immune system. About two-thirds of all human bacterial infections are now believed to be caused by biofilms, highlighting the need for novel agents that can prevent or reverse biofilm formation. In this work, a 96-well plate screening approach and different detection strategies were used to measure the antibiofilm activity and selectivity of a series of peptides based on the naturally occurring cationic Trp-rich WWW peptide tritrpticin. Structural changes in the peptide backbone and the introduction of a nonnatural amino acid were shown to improve the clinical potential of several peptide variants. View this paper
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Articles (218)

  • Article
  • Open Access
3 Citations
1,530 Views
17 Pages

19 February 2025

The regioselectivity and molecular mechanism of the (3+2) cycloaddition reaction between E-2-(trimethylsilyl)-1-nitroethene and arylonitrile N-oxides were explored on the basis of the ωB97XD/6-311+G(d) (PCM) quantumchemical calculations. It was...

  • Article
  • Open Access
3 Citations
1,226 Views
17 Pages

19 February 2025

III-nitrides are crucial materials for solar flow batteries due to their versatile properties. In contrast to the well-studied MOVPE reaction mechanism for AlN and GaN, few works report gas-phase mechanistic studies on the growth of InN. To better un...

  • Review
  • Open Access
6 Citations
4,849 Views
53 Pages

Research Progress in Ionic Liquid-Based Electrolytes for Electrochromic Devices

  • Hao Zhang,
  • Yixuan Liu,
  • Xuehan Wang,
  • Keying Feng,
  • Qilin Wang,
  • Zheng Chen and
  • Zhenhua Jiang

19 February 2025

Electrochromic (EC) technology has become one of the smart technologies with the most potential for development and application at this stage. Based on electrochromic devices (ECDs), this technology has shown extraordinary potential in the fields of...

  • Article
  • Open Access
1 Citations
1,715 Views
31 Pages

Antitumor Activity, Mechanisms of Action and Phytochemical Profiling of Sub-Fractions Obtained from Ulex gallii Planch. (Fabaceae): A Medicinal Plant from Galicia (Spain)

  • Lucía Bada,
  • Hussain Shakeel Butt,
  • Elías Quezada,
  • Aitor Picos,
  • Helle Wangensteen,
  • Kari Tvete Inngjerdingen,
  • José Gil-Longo and
  • Dolores Viña

19 February 2025

The plant kingdom serves as a valuable resource for cancer drug development. This study explored the antitumor activity of different sub-fractions (hexane, dichloromethane and methanol) of U. gallii (gorse) methanol extract in glioblastoma (U-87MG an...

  • Article
  • Open Access
5 Citations
2,587 Views
19 Pages

Determination of the Polyphenol Composition of Raspberry Leaf Using LC-MS/MS

  • Hind Mesfer S. Alkhudaydi,
  • Esther Njeri Muriuki and
  • Jeremy P. E. Spencer

19 February 2025

Background: Raspberry leaf (RL; Rubus idaeus) is a by-product of raspberry cultivation and has been proposed to be a rich source of micronutrients and potential bioactive components, including polyphenols. However, the precise chemical composition of...

  • Article
  • Open Access
2 Citations
1,044 Views
17 Pages

Stability and Reusability of Tungsten Catalyst on Structured Support in Catalytic Ozonation of Textile Wastewater

  • Aleksandra Kędzierska-Sar,
  • Maciej Fronczak,
  • Marta Gmurek and
  • Lucyna Bilińska

19 February 2025

Since heterogeneous catalytic ozonation (HCO) has become a leading trend in advanced oxidation processes, finding new prospective catalysts has become crucial. Plasma-enhanced chemical vapor deposition (PECVD) is a method of thin-layer deposition tha...

  • Article
  • Open Access
1,076 Views
10 Pages

19 February 2025

The durability of the materials is often limited as they fade under the influence of external factors, particularly light. The present research aimed to study the photodegradation of commercial inkjet inks in an aqueous solution. The results were com...

  • Review
  • Open Access
3 Citations
1,737 Views
45 Pages

19 February 2025

Xanthone dimers, a distinctive class of natural metabolites renowned for their unique structures, are abundantly present in a diverse array of angiosperms, fungi, and lichens. These compounds not only exhibit remarkable diversity but also possess a b...

  • Article
  • Open Access
3 Citations
1,315 Views
19 Pages

19 February 2025

In this article, we introduce nano-differential fluorimetry (nano-DSF) as an analytical technique that is suitable for investigating polyphenol–protein interactions in solution. Nano-DSF monitors conformational changes in proteins induced by ex...

  • Article
  • Open Access
1 Citations
1,034 Views
12 Pages

19 February 2025

Catalytic alkane hydroxylation activities of the iron complex encapsulated into the micropore of the Y-type zeolite and mesoporous zeolites, the latter of which were obtained by the partial removal of aluminum and alkaline treatment, have been explor...

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Molecules - ISSN 1420-3049