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Biology, Volume 10, Issue 10

2021 October - 127 articles

Cover Story: In this article, Zieneldien et al. provided a thorough review of the technologies employed by currently utilized COVID-19 vaccines while also providing a comparison of the efficacy rates and side effects. SARS-CoV-2 was first reported in December 2019 in Wuhan, China, and has since infected over 219 million individuals. Due to this, vaccine development was considered a priority by global health agencies. Even though the most popular COVID-19 vaccines have been shown to be efficacious, it is still critical to assess which vaccines are the most effective, while also providing considerations for future vaccine strategies and development to properly address future infection and viral mutation. View this paper
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Articles (127)

  • Review
  • Open Access
20 Citations
5,240 Views
27 Pages

Human Drug Pollution in the Aquatic System: The Biochemical Responses of Danio rerio Adults

  • Manuela Mauro,
  • Valentina Lazzara,
  • Vincenzo Arizza,
  • Claudio Luparello and ,
  • Vincenzo Ferrantelli,
  • Gaetano Cammilleri,
  • Luigi Inguglia and
  • Mirella Vazzana
  • + 3 authors+ 0 author

19 October 2021

To date, drug pollution in aquatic systems is an urgent issue, and Danio rerio is a model organism to study the toxicological effects of environmental pollutants. The scientific literature has analyzed the effect of human drug pollution on the bioche...

  • Article
  • Open Access
13 Citations
6,279 Views
21 Pages

Sex Associated Effects of Noise Pollution in Stone Sculpin (Paracottus knerii) as a Model Object in the Context of Human-Induced Rapid Environmental Change

  • Yulia P. Sapozhnikova,
  • Anastasia G. Koroleva,
  • Vera M. Yakhnenko,
  • Igor V. Khanaev and ,
  • Olga Yu. Glyzina,
  • Tatyana N. Avezova,
  • Aleksandra A. Volkova,
  • Angela V. Mushinskaya,
  • Marina L. Tyagun and
  • Lyubov V. Sukhanova
  • + 10 authors+ 5 authors

19 October 2021

This work simulates the consequences of HIREC using stone sculpins as model organisms. Sex-dependent effects of long-term noise exposure at mean sound pressure levels of 160–179 dB re 1 μPa (SPLpk–pk) were measured. We applied a multilevel approach t...

(This article belongs to the Special Issue Biomarkers in Stress Ecology—From the Gene to Population)
  • Article
  • Open Access
11 Citations
5,008 Views
27 Pages

19 October 2021

Dengue virus infection is a global health problem for which there have been challenges to obtaining a cure. Current vaccines and anti-viral drugs can only be narrowly applied in ongoing clinical trials. We employed computational methods based on stru...

  • Article
  • Open Access
8 Citations
5,368 Views
15 Pages

Haematological, Biochemical and Hormonal Biomarkers of Heat Intolerance in Military Personnel

  • Faith O. Alele,
  • Bunmi S. Malau-Aduli,
  • Aduli E. O. Malau-Aduli and
  • Melissa J. Crowe

19 October 2021

Heat intolerance is the inability to withstand heat stress and this may occur due to exertional heat stroke (EHS). However, it is unknown if heat intolerance is associated with immune and hormonal disturbances. This study investigates haematological,...

(This article belongs to the Special Issue Response and Adaptation during Human Exercise: From Physiology, Metabolism and Musculoskeletal Modelling to Understand Functional Disorders)
  • Article
  • Open Access
30 Citations
8,034 Views
16 Pages

Enhancement of the Aroma Compound 2-Acetyl-1-pyrroline in Thai Jasmine Rice (Oryza sativa) by Rhizobacteria under Salt Stress

  • Kawiporn Chinachanta,
  • Arawan Shutsrirung,
  • Laetitia Herrmann,
  • Didier Lesueur and
  • Wasu Pathom-aree

19 October 2021

Thai jasmine rice (Oryza sativa L. KDML105), particularly from inland salt-affected areas in Thailand, is both domestically and globally valued for its unique aroma and high grain quality. The key aroma compound, 2-acetyl-1-pyrroline (2AP), has under...

(This article belongs to the Special Issue Beneficial Soil Bacteria: Many Recipes to Promote Plant Growth and Protection)
  • Article
  • Open Access
20 Citations
3,999 Views
16 Pages

Quantifying Leaf Trait Covariations and Their Relationships with Plant Adaptation Strategies along an Aridity Gradient

  • Yanzheng Yang,
  • Le Kang,
  • Jun Zhao,
  • Ning Qi and ,
  • Ruonan Li,
  • Zhongming Wen,
  • Jalal Kassout,
  • Changhui Peng,
  • Guanghui Lin and
  • Hua Zheng
  • + 5 authors+ 0 author

19 October 2021

A trait-based approach is an effective way to quantify plant adaptation strategies in response to changing environments. Single trait variations have been well depicted before; however, multi-trait covariations and their roles in shaping plant adapta...

(This article belongs to the Section Ecology)
  • Article
  • Open Access
16 Citations
4,003 Views
18 Pages

19 October 2021

The plant cell wall (CW) is an outer cell skeleton that plays an important role in plant growth and protection against both biotic and abiotic stresses. Signals and molecules produced during host–pathogen interactions have been proven to be involved...

(This article belongs to the Special Issue The Secrets Hidden in the Plant Cell Wall: From Plant Biology and Biotechnology to Human Health)
  • Article
  • Open Access
15 Citations
12,030 Views
22 Pages

Efficacy and Safety of Filgrastim and Its Biosimilars to Prevent Febrile Neutropenia in Cancer Patients: A Prospective Study and Meta-Analysis

  • Shruti Rastogi,
  • Vivekananda Kalaiselvan,
  • Sher Ali,
  • Ajaz Ahmad and ,
  • Sameer Ahmad Guru and
  • Maryam Sarwat
  • + 1 author+ 0 author

19 October 2021

Background: The aim of this review and meta-analysis was to identify, assess, meta-analyze and summarize the comparative effectiveness and safety of filgrastim in head-to-head trials with placebo/no treatment, pegfilgrastim (and biosimilar filgrastim...

  • Article
  • Open Access
15 Citations
6,530 Views
14 Pages

Identification of Bioactive Phytochemicals from Six Plants: Mechanistic Insights into the Inhibition of Rumen Protozoa, Ammoniagenesis, and α-Glucosidase

  • Aurele Gnetegha Ayemele,
  • Lu Ma,
  • Xiumei Li,
  • Peilong Yang and ,
  • Jianchu Xu,
  • Zhongtang Yu and
  • Dengpan Bu
  • + 2 authors+ 0 author

18 October 2021

Rumen protozoa prey on feed-degrading bacteria synthesizing microbial protein, lowering nitrogen utilization efficiency in ruminants. In this in vitro study, we evaluated six plants (Adansonia digitata, Flemingia macrophylla, Kalimeris indica,Brassic...

(This article belongs to the Special Issue Gut Microbiome Manipulation: Focus on Microbiome Characterization, Diagnostics and Therapeutic Indications)
  • Review
  • Open Access
80 Citations
26,270 Views
18 Pages

The Role of Satellite Cells in Skeletal Muscle Regeneration—The Effect of Exercise and Age

  • Agnieszka Kaczmarek,
  • Mateusz Kaczmarek,
  • Maria Ciałowicz,
  • Filipe Manuel Clemente and ,
  • Paweł Wolański,
  • Georgian Badicu and
  • Eugenia Murawska-Ciałowicz
  • + 2 authors+ 0 author

18 October 2021

The population of satellite cells (mSCs) is highly diversified. The cells comprising it differ in their ability to regenerate their own population and differentiate, as well as in the properties they exhibit. The heterogeneity of this group of cells...

(This article belongs to the Special Issue Biological Mechanisms Underlying Physical Fitness and Sports Performance)
  • Article
  • Open Access
40 Citations
5,343 Views
16 Pages

Predicting the Potential Global Distribution of Amblyomma americanum (Acari: Ixodidae) under Near Current and Future Climatic Conditions, Using the Maximum Entropy Model

  • Delong Ma,
  • Xinchang Lun,
  • Chao Li,
  • Ruobing Zhou and ,
  • Zhe Zhao,
  • Jun Wang,
  • Qinfeng Zhang and
  • Qiyong Liu
  • + 3 authors+ 0 author

18 October 2021

Amblyomma americanum (the lone star tick) is a pathogen vector, mainly from eastern North America, that bites humans. With global integration and climate change, some ticks that are currently confined to a certain place may begin to spread out; some...

(This article belongs to the Special Issue The Impact of Climate Change on Ecosystems and Human Health)
  • Review
  • Open Access
496 Citations
25,103 Views
24 Pages

18 October 2021

Microalgae are a valuable natural resource for a variety of value-added products. The growth of microalgae is determined by the impact of many factors, but, from the point of view of the implementation of autotrophic growth, light is of primary impor...

(This article belongs to the Section Biotechnology)
  • Review
  • Open Access
87 Citations
10,360 Views
24 Pages

Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological Properties

  • Pavitra Nandagopal,
  • Anthony Nyangson Steven,
  • Liong-Wai Chan,
  • Zaidah Rahmat and ,
  • Haryati Jamaluddin and
  • Nur Izzati Mohd Noh
  • + 1 author+ 0 author

18 October 2021

Cyanobacteria are the most abundant oxygenic photosynthetic organisms inhabiting various ecosystems on earth. As with all other photosynthetic organisms, cyanobacteria release oxygen as a byproduct during photosynthesis. In fact, some cyanobacterial...

(This article belongs to the Section Microbiology)
  • Article
  • Open Access
21 Citations
5,700 Views
10 Pages

18 October 2021

In the Valdichiana area (Tuscany, Italy) an ancient native landrace of elephant garlic (Allium ampeloprasum L.), locally known as “Aglione della Valdichiana”, has long been cultivated. The aim of this study was to check whether there are differences...

(This article belongs to the Section Plant Science)
  • Article
  • Open Access
16 Citations
4,269 Views
16 Pages

Population Ecology and Genetic Diversity of the Invasive Alien Species Procambarus clarkii in Lake Trasimeno (Italy)

  • Ambrosius Josef Martin Dörr,
  • Melissa Scoparo,
  • Irene Cardinali,
  • Gianandrea La Porta and ,
  • Barbara Caldaroni,
  • Gabriele Magara,
  • Matteo Pallottini,
  • Roberta Selvaggi,
  • Beniamino Cenci-Goga and
  • Antonia Concetta Elia
  • + 8 authors+ 3 authors

18 October 2021

The deliberate or accidental introduction of invasive alien species (IAS) causes negative ecological and economic impacts altering ecosystem processes, imperiling native species and causing damage to human endeavors. A monthly monitoring program was...

(This article belongs to the Special Issue Biological Invasions: From Prevention and Management to Ecosystem Restoration)
  • Article
  • Open Access
8 Citations
4,742 Views
20 Pages

Induced Pluripotent Stem Cell-Derived Cardiomyocytes with SCN5A R1623Q Mutation Associated with Severe Long QT Syndrome in Fetuses and Neonates Recapitulates Pathophysiological Phenotypes

  • Emiko Hayama,
  • Yoshiyuki Furutani,
  • Nanako Kawaguchi,
  • Akiko Seki and ,
  • Yoji Nagashima,
  • Keisuke Okita,
  • Daiji Takeuchi,
  • Rumiko Matsuoka,
  • Kei Inai and
  • Toshio Nakanishi
  • + 6 authors+ 1 author

18 October 2021

The SCN5A R1623Q mutation is one of the most common genetic variants associated with severe congenital long QT syndrome 3 (LQT3) in fetal and neonatal patients. To investigate the properties of the R1623Q mutation, we established an induced pluripote...

(This article belongs to the Special Issue Stem Cells for Cardiovascular Biology and Medicine)
  • Article
  • Open Access
16 Citations
3,940 Views
11 Pages

Relationship between Plasma Concentrations of Afatinib and the Onset of Diarrhea in Patients with Non-Small Cell Lung Cancer

  • Hayato Yokota,
  • Kazuhiro Sato,
  • Sho Sakamoto,
  • Yuji Okuda and ,
  • Mariko Asano,
  • Masahide Takeda,
  • Katsutoshi Nakayama and
  • Masatomo Miura
  • + 3 authors+ 0 author

17 October 2021

We evaluated the area under the plasma concentration–time curve (AUC) of afatinib required to avoid the onset of grade 2 or higher diarrhea. The C0 and AUC0–24 of afatinib were significant higher in patients with grade 2 diarrhea than in those with g...

(This article belongs to the Section Cancer Biology)
  • Feature Paper
  • Review
  • Open Access
10 Citations
3,729 Views
11 Pages

16 October 2021

Pulmonary diseases present a significant burden worldwide and lead to severe morbidity and mortality. Lung inflammation caused by interactions with either viruses, bacteria or fungi is a prominent characteristic of many pulmonary diseases. Tobacco sm...

(This article belongs to the Section Biochemistry and Molecular Biology)
  • Article
  • Open Access
9 Citations
3,631 Views
16 Pages

Antiviral Function of NKEF against VHSV in Rainbow Trout

  • Veronica Chico,
  • Maria Elizabhet Salvador-Mira,
  • Ivan Nombela,
  • Sara Puente-Marin and ,
  • Luis Perez,
  • Luis Mercado and
  • Maria del Mar Ortega-Villaizan
  • + 2 authors+ 0 author

15 October 2021

Natural killer enhancing factor (NKEF) belongs to the peroxiredoxin family of proteins, a group of antioxidants that has been extensively studied in mammals. Recently, we identified NKEF in the immunoprecipitated proteome of rainbow trout red blood c...

  • Review
  • Open Access
20 Citations
8,576 Views
22 Pages

15 October 2021

The trade of non-native pets, especially of non-domesticated and exotic animals, and their subsequent release and establishment of populations is one of the major pathways of introduction for invasive alien reptiles, amphibia, birds and mammals. Here...

(This article belongs to the Special Issue Biological Invasions: From Prevention and Management to Ecosystem Restoration)
  • Review
  • Open Access
35 Citations
7,032 Views
21 Pages

15 October 2021

Sporadic Alzheimer’s Disease (AD) is the most common form of dementia, and its severity is characterized by the progressive formation of tau neurofibrillary tangles along a well-described path through the brain. This spatial progression provides the...

(This article belongs to the Special Issue Selective Vulnerability in Neurodegenerative Diseases)
  • Article
  • Open Access
20 Citations
4,669 Views
14 Pages

15 October 2021

The Bemisia tabaci cryptic species contains 39 known mitotypes of which the B and Q are best recognized for having established outside their extant endemic range. In the 1980s, previously uncharacterized haplotype(s) of the B mitotype rapidly establi...

(This article belongs to the Special Issue Biological Invasions: From Prevention and Management to Ecosystem Restoration)
  • Article
  • Open Access
19 Citations
4,674 Views
23 Pages

Pomacea canaliculata Ampullar Proteome: A Nematode-Based Bio-Pesticide Induces Changes in Metabolic and Stress-Related Pathways

  • Federica Boraldi,
  • Francesco Demetrio Lofaro,
  • Giulia Bergamini,
  • Agnese Ferrari and
  • Davide Malagoli

15 October 2021

Pomacea canaliculata is a freshwater gastropod known for being both a highly invasive species and one of the possible intermediate hosts of the mammalian parasite Angiostrongylus cantonensis. With the aim of providing new information concerning P. ca...

  • Article
  • Open Access
4 Citations
4,469 Views
10 Pages

Mitochondrial Translation Occurs Preferentially in the Peri-Nuclear Mitochondrial Network of Cultured Human Cells

  • Christin A. Albus,
  • Rolando Berlinguer-Palmini,
  • Caroline Hewison,
  • Fiona McFarlane and ,
  • Elisabeta-Ana Savu,
  • Robert N. Lightowlers,
  • Zofia M. Chrzanowska-Lightowlers and
  • Matthew Zorkau
  • + 3 authors+ 0 author

15 October 2021

Human mitochondria are highly dynamic organelles, fusing and budding to maintain reticular networks throughout many cell types. Although extending to the extremities of the cell, the majority of the network is concentrated around the nucleus in most...

(This article belongs to the Special Issue Mitochondrial Heterogeneity)
  • Article
  • Open Access
15 Citations
4,715 Views
13 Pages

15 October 2021

Tricholoma matsutake forms a symbiotic association with coniferous trees, developing mycelial aggregations, called ‘shiro’, which are characterized by distinct chemical and physical properties from nearby forest bulk soil. The fungal diversity living...

(This article belongs to the Special Issue Plant–Fungi Interaction: Two-Edged Sword for Plant Growth, Production and Storage)
  • Review
  • Open Access
81 Citations
14,934 Views
13 Pages

Sugarcane Ratooning Ability: Research Status, Shortcomings, and Prospects

  • Fu Xu,
  • Zhoutao Wang,
  • Guilong Lu,
  • Rensen Zeng and
  • Youxiong Que

15 October 2021

Sugarcane is an important sugar crop and it can be subjected to ratooning for several years. The advantages of ratooning include quality improvement, efficiency enhancement, and reduced costs and energy use. The genotype, environment, cultivation man...

  • Review
  • Open Access
91 Citations
31,165 Views
26 Pages

Nitric Oxide as a Central Molecule in Hypertension: Focus on the Vasorelaxant Activity of New Nitric Oxide Donors

  • Gabriela Maria da Silva,
  • Mirelly Cunha da Silva,
  • Déborah Victória Gomes Nascimento,
  • Ellen Mayara Lima Silva and ,
  • Fabíola Furtado Fialho Gouvêa,
  • Luiz Gonzaga de França Lopes,
  • Alice Valença Araújo,
  • Kelli Nogueira Ferraz Pereira and
  • Thyago Moreira de Queiroz
  • + 4 authors+ 0 author

14 October 2021

Cardiovascular diseases include all types of disorders related to the heart or blood vessels. High blood pressure is an important risk factor for cardiac complications and pathological disorders. An increase in circulating angiotensin-II is a potent...

  • Article
  • Open Access
12 Citations
5,523 Views
15 Pages

14 October 2021

Extra virgin olive oil (EVOO) is important in people’s daily diets. Paracetamol is a widely used analgesic and antipyretic drug. The aim of this study is to investigate the protective effect of EVOO against hematotoxicity and testicular toxicity indu...

  • Perspective
  • Open Access
2 Citations
10,583 Views
7 Pages

The Curious Case of Earthworms and COVID-19

  • Janeck J. Scott-Fordsmand and
  • Monica J. B. Amorim

14 October 2021

Earthworms have been used for centuries in traditional medicine and are used globally as an ecotoxicological standard test species. Studies of the earthworm Eisenia fetida have shown that exposure to nanomaterials activates a primary corona-response,...

(This article belongs to the Section Infection Biology)
  • Review
  • Open Access
28 Citations
6,750 Views
14 Pages

14 October 2021

Milk protein (MP) synthesis in the mammary gland of dairy cows is a complex biological process. As the substrates for protein synthesis, amino acids (AAs) are the most important nutrients for milk synthesis. Free AAs (FAAs) are the main precursors of...

  • Article
  • Open Access
10 Citations
4,489 Views
18 Pages

Carrier-Free Cellular Transport of CRISPR/Cas9 Ribonucleoprotein for Genome Editing by Cold Atmospheric Plasma

  • Haodong Cui,
  • Min Jiang,
  • Wenhua Zhou,
  • Ming Gao and ,
  • Rui He,
  • Yifan Huang,
  • Paul K. Chu and
  • Xue-Feng Yu
  • + 3 authors+ 0 author

13 October 2021

A carrier-free CRISPR/Cas9 ribonucleoprotein delivery strategy for genome editing mediated by a cold atmospheric plasma (CAP) is described. The CAP is promising in many biomedical applications due to efficient production of bioactive ionized species....

(This article belongs to the Collection Applied Physics in Cancer Cells)
  • Article
  • Open Access
15 Citations
4,006 Views
19 Pages

A Multidisciplinary Approach to Evaluate the Effects of Contaminants of Emerging Concern on Natural Freshwater and Brackish Water Phytoplankton Communities

  • Paolo Pastorino,
  • Andrea Broccoli,
  • Elisa Bagolin,
  • Serena Anselmi and ,
  • Andrea Cavallo,
  • Marino Prearo and
  • Monia Renzi
  • + 2 authors+ 0 author

13 October 2021

Ecotoxicological assays on monospecific phytoplankton have limited application for detecting the effects of environmental pollutants on multiple species communities. With this study, we took an ecotoxicological, ecological, and biochemical approach t...

(This article belongs to the Section Toxicology)
  • Article
  • Open Access
40 Citations
4,362 Views
18 Pages

Effects of Low Stocking Densities on Zootechnical Parameters and Physiological Responses of Rainbow Trout (Oncorhynchus mykiss) Juveniles

  • Jérôme Roy,
  • Frederic Terrier,
  • Michael Marchand,
  • Alexandre Herman and ,
  • Cécile Heraud,
  • Anne Surget,
  • Anthony Lanuque,
  • Franck Sandres and
  • Lucie Marandel
  • + 4 authors+ 0 author

13 October 2021

The present study investigated the effect of low stocking density on growth, survival, feed parameters and physiological responses (blood metabolites, welfare indicators, immune biomarkers, and transcriptomic responses of stress and immune-related ge...

(This article belongs to the Section Behavioural Biology)
  • Article
  • Open Access
11 Citations
3,568 Views
14 Pages

Decreased Expression of Cytotoxic Proteins in Decidual CD8+ T Cells in Preeclampsia

  • Violeta Soljic,
  • Maja Barbaric,
  • Martina Vukoja,
  • Marina Curlin and ,
  • Martina Orlovic Vlaho,
  • Edita Cerni Obrdalj,
  • Lidija Lasic Arapovic,
  • Daniela Bevanda Glibo and
  • Katarina Vukojevic
  • + 4 authors+ 0 author

13 October 2021

In our study, we aimed to establish expression of cytotoxic CD8+ T cells in the decidua basalis and the maternal peripheral blood (mPBL) of severe and mild preeclampsia (PE) and compare to healthy pregnancies. Decidual tissue and mPBL of 10 women wit...

  • Article
  • Open Access
5 Citations
5,860 Views
10 Pages

Facial Hair Decreases Fit Factor of Masks and Respirators in Healthcare Providers

  • Borja De-Yñigo-Mojado,
  • Ricardo Becerro-de-Bengoa-Vallejo,
  • Marta Elena Losa-Iglesias,
  • Javier Madera-García and ,
  • David Rodríguez-Sanz,
  • Cesar Calvo-Lobo,
  • Daniel López-López,
  • María Teresa Angulo-Carrere and
  • Marta San-Antolín
  • + 4 authors+ 0 author

12 October 2021

In response to the current state of the COVID-19 pandemic, healthcare providers are using common surgical masks and filtering respirators in conjunction with the presence of facial hair, which could lead to a large number of particles passing into th...

(This article belongs to the Special Issue Human Bodywork: Applications in Health, Disease, and Rehabilitation)
  • Article
  • Open Access
31 Citations
5,927 Views
18 Pages

Genomic Features and Molecular Function of a Novel Stress-Tolerant Bacillus halotolerans Strain Isolated from an Extreme Environment

  • Xiaohui Wu,
  • Huijun Wu,
  • Ruoyi Wang,
  • Zhengqi Wang and ,
  • Yaming Zhang,
  • Qin Gu,
  • Ayaz Farzand,
  • Xue Yang,
  • Mikhail Semenov and
  • Xuewen Gao
  • + 7 authors+ 2 authors

12 October 2021

Due to its topographical position and climatic conditions, the Qinghai–Tibet Plateau possesses abundant microorganism resources. The extremophilic strain KKD1 isolated from Hoh Xil possesses strong stress tolerance, enabling it to propagate under hig...

(This article belongs to the Section Microbiology)
  • Article
  • Open Access
24 Citations
3,984 Views
19 Pages

Support Vector Machine-Based Classification of Vasovagal Syncope Using Head-Up Tilt Test

  • Shahadat Hussain,
  • Zahid Raza,
  • Giorgio Giacomini and
  • Nandu Goswami

12 October 2021

Syncope is the medical condition of loss of consciousness triggered by the momentary cessation of blood flow to the brain. Machine learning techniques have been established to be very effective way to address such problems, where a class label is pre...

(This article belongs to the Section Physiology)
  • Article
  • Open Access
13 Citations
6,083 Views
8 Pages

Changes in MOTS-c Level in the Blood of Pregnant Women with Metabolic Disorders

  • Małgorzata Wojciechowska,
  • Ewa Pruszyńska-Oszmałek,
  • Paweł A. Kołodziejski,
  • Hanna Krauss and ,
  • Natalia Leciejewska,
  • Dawid Szczepankiewicz,
  • Jakub Bień,
  • Marek Skrzypski,
  • Maciej Wilczak and
  • Maciej Sassek
  • + 5 authors+ 0 author

12 October 2021

MOTS-c peptide is a member of the group of mitochondria-derived peptides (MDP). It is a product of the open reading frame in the 12S RNA gene. Due to its features and functions in the body, this peptide is classified as a hormone. The first publicati...

  • Article
  • Open Access
12 Citations
3,995 Views
12 Pages

Peptide Signatures for Prognostic Markers of Pancreatic Cancer by MALDI Mass Spectrometry Imaging

  • Florian N. Loch,
  • Oliver Klein,
  • Katharina Beyer,
  • Frederick Klauschen and ,
  • Christian Schineis,
  • Johannes C. Lauscher,
  • Georgios A. Margonis,
  • Claudius E. Degro,
  • Wael Rayya and
  • Carsten Kamphues
  • + 5 authors+ 0 author

12 October 2021

Despite the overall poor prognosis of pancreatic cancer there is heterogeneity in clinical courses of tumors not assessed by conventional risk stratification. This yields the need of additional markers for proper assessment of prognosis and multimoda...

(This article belongs to the Section Cancer Biology)
  • Hypothesis
  • Open Access
6 Citations
5,357 Views
22 Pages

12 October 2021

The relevance of bacteria to subjective experiences or qualia is underappreciated. Here, I make four proposals. Firstly, living systems traverse sequences of active states that determine their behaviour; these states result from competitive coherence...

  • Review
  • Open Access
57 Citations
14,536 Views
38 Pages

Borreliae Part 1: Borrelia Lyme Group and Echidna-Reptile Group

  • Giusto Trevisan,
  • Marina Cinco,
  • Sara Trevisini,
  • Nicola di Meo and ,
  • Karin Chersi,
  • Maurizio Ruscio,
  • Patrizia Forgione and
  • Serena Bonin
  • + 3 authors+ 0 author

12 October 2021

Borreliae are divided into three groups, namely the Lyme group (LG), the Echidna-Reptile group (REPG) and the Relapsing Fever group (RFG). Currently, only Borrelia of the Lyme and RF groups (not all) cause infection in humans. Borreliae of the Echidn...

(This article belongs to the Special Issue Advances in the Biology of Leptospira, Borrelia and Other Spirochetes)
  • Article
  • Open Access
18 Citations
4,409 Views
13 Pages

12 October 2021

An energy-saving light emitting diode (LED) system allows for adjustment of light quality, which affects plant development and metabolic processes in in vitro cultures. The study investigated the content of endogenous carbohydrates and the condition...

(This article belongs to the Special Issue Physiological, Biochemical, and Molecular Response in Plants under Light-Emitting Diode (LED) Treatment)
  • Article
  • Open Access
4 Citations
4,113 Views
14 Pages

11 October 2021

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a novel pandemic event following the swine flu that occurred in 2009, which was caused by the influenza A virus (H1N1 sub...

(This article belongs to the Special Issue Coronavirus Disease 2019 (COVID-19))
  • Review
  • Open Access
18 Citations
5,663 Views
20 Pages

Extracellular DNA: Insight of a Signal Molecule in Crop Protection

  • Ireri Alejandra Carbajal-Valenzuela,
  • Gabriela Medina-Ramos,
  • Laura Helena Caicedo-Lopez,
  • Alejandra Jiménez-Hernández and ,
  • Adrian Esteban Ortega-Torres,
  • Luis Miguel Contreras-Medina,
  • Irineo Torres-Pacheco and
  • Ramón Gerardo Guevara-González
  • + 3 authors+ 0 author

11 October 2021

Agricultural systems face several challenges in terms of meeting everyday-growing quantities and qualities of food requirements. However, the ecological and social trade-offs for increasing agricultural production are high, therefore, more sustainabl...

(This article belongs to the Section Plant Science)
  • Review
  • Open Access
11 Citations
4,577 Views
13 Pages

Extracellular Matrix Components as Diagnostic Tools in Inflammatory Bowel Disease

  • Laura Golusda,
  • Anja A. Kühl,
  • Britta Siegmund and
  • Daniela Paclik

11 October 2021

Work from the last years indicates that the extracellular matrix (ECM) plays a direct role in various cellular processes, including proliferation, migration and differentiation. Besides homeostatic processes, its regulatory function in inflammation b...

(This article belongs to the Special Issue Pathological Changes of the Extracellular Matrix as Diagnostic Target)
  • Article
  • Open Access
9 Citations
5,033 Views
11 Pages

ARGEOS: A New Bioinformatic Tool for Detailed Systematics Search in GEO and ArrayExpress

  • Gleb E. Gavrish,
  • Dmitry V. Chistyakov and
  • Marina G. Sergeeva

11 October 2021

Conduct a reanalysis of transcriptome data for studying intracellular signaling or solving other experimental problems is becoming increasingly popular. Gene expression data are archived as microarray or RNA-seq datasets mainly in two public database...

(This article belongs to the Special Issue Differential Gene Expression and Coexpression)
  • Article
  • Open Access
21 Citations
4,970 Views
23 Pages

Biodiversity of Pathogenic and Toxigenic Seed-Borne Mycoflora of Wheat in Egypt and Their Correlations with Weather Variables

  • Yasser M. Shabana,
  • Younes M. Rashad,
  • Khalid M. Ghoneem,
  • Nehal S. Arafat and ,
  • Dalia G. Aseel,
  • Aiming Qi,
  • Benjamin Richard and
  • Bruce D. L. Fitt
  • + 3 authors+ 0 author

11 October 2021

Surveillance investigations for pathogenic and toxigenic fungi are important to refine our understanding of their epidemiology and help in predicting their outbreaks. During 2019, 198 samples of wheat grains were collected from 25 wheat-growing gover...

(This article belongs to the Section Microbiology)
  • Systematic Review
  • Open Access
32 Citations
5,787 Views
16 Pages

The Modulation of Gut Microbiota Composition in the Pathophysiology of Gestational Diabetes Mellitus: A Systematic Review

  • Thubasni Kunasegaran,
  • Vinod R. M. T. Balasubramaniam,
  • Valliammai Jayanthi T. Arasoo,
  • Uma Devi Palanisamy and
  • Amutha Ramadas

11 October 2021

General gut microbial dysbiosis in diabetes mellitus, including gestational diabetes mellitus (GDM), has been reported in a large body of literature. However, evidence investigating the association between specific taxonomic classes and GDM is lackin...

(This article belongs to the Section Microbiology)
  • Article
  • Open Access
28 Citations
7,011 Views
15 Pages

Bioactive and Physicochemical Characteristics of Natural Food: Palmyra Palm (Borassus flabellifer Linn.) Syrup

  • Dung Huynh Thi Le,
  • Chien-Shan Chiu,
  • Yung-Jia Chan,
  • Chiun-Chuan R. Wang and ,
  • Zeng-Chin Liang,
  • Chang-Wei Hsieh,
  • Wen-Chien Lu,
  • Amanda Tresiliana Mulio,
  • Yin-Jun Wang and
  • Po-Hsien Li
  • + 5 authors+ 0 author

11 October 2021

Palmyra palm syrup, produced from Borassus flabellifer flowers’ sap, is rich in nutrients and minerals and has unique flavors. This study evaluated the in vitro antioxidant activity, physicochemical characteristics, and Maillard reaction products of...

(This article belongs to the Special Issue Functional Foods: Bioactivity, Bioavailability, and Biological Characteristics)
  • Article
  • Open Access
11 Citations
5,894 Views
26 Pages

Skull Morphology, Bite Force, and Diet in Insectivorous Bats from Tropical Dry Forests in Colombia

  • Leidy Azucena Ramírez-Fráncel,
  • Leidy Viviana García-Herrera,
  • Sergio Losada-Prado,
  • Gladys Reinoso-Flórez and ,
  • Burton K. Lim,
  • Francisco Sánchez,
  • Alfonso Sánchez-Hernández and
  • Giovany Guevara
  • + 3 authors+ 0 author

9 October 2021

In Neotropical bats, studies on bite force have focused mainly on differences in trophic ecology, and little is known about whether factors other than body size generate interspecific differences in bite force amongst insectivorous bats and, conseque...

(This article belongs to the Section Ecology)

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Biology - ISSN 2079-7737