Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Redox Balance and Proteostasis Surveillance in Neurodegenerative Disorders submission deadline 30 Sep 2024 | Viewed by 195 | Submission Open
Keywords: redox homeostasis; oxidative stress; antioxidant response; proteostasis; protein folding; protein oxidation; unfolded protein response; ubiquitin proteosome system; autophagy; neurodegeneration
(This special issue belongs to the Section Molecular Medicine)
New Insights into the Membranes of Anoxygenic Phototrophic Bacteria submission deadline 30 Sep 2024 | Viewed by 176 | Submission Open
Keywords: anoxygenic phototrophs; light harvesting; membrane dynamics; molecular evolution; reaction centers
(This special issue belongs to the Section Molecular Structure and Dynamics)
Advanced Organometallic Syntheses for Biomedical Applications
edited by Bala Krishna Moku
submission deadline 30 Sep 2024 | Viewed by 174 | Submission Open
Keywords: advanced organometallic syntheses; biomedical applications; drug discovery; disease treatment; imaging; targeted therapy
(This special issue belongs to the Section Synthetic Biology and Bioengineering)
Cutting-Edge Research on the Analysis of Small Biomolecules in Foods, Plants, and Biological Samples, Volume II submission deadline 30 Sep 2024 | Viewed by 162 | Submission Open
Keywords: bioactive food ingredients (primary and secondary metabolites); secondary metabolites— natural products liquid chromatography-mass spectrometry; Fourier transform infrared (FTIR) and Raman spectroscopic analysis; gas chromatography-mass spectrometry; high-resolution mass spectrometry; lipids— amino acids— carbohydrates; polyphenols– terpenes
(This special issue belongs to the Section Natural and Bio-derived Molecules)
The Role of Modulating Intracellular Signaling in Immune System
edited by
submission deadline 30 Sep 2024 | Viewed by 152 | Submission Open
Keywords: signaling pathway; inflammation; autoimmune disease; treatment
(This special issue belongs to the Section Molecular Biology)
Genetic and Structural Analyses of SARS-CoV-2 and Its Variants
edited by
submission deadline 30 Sep 2024 | Viewed by 144 | Submission Open
Keywords: SARS-CoV-2 variants; protein variants; protein structure; virus evolution; mutations; structural bioinformatics; molecular phylogenesis; host– pathogen molecular interactions; molecular immunology; drug discovery
New Insights and Potential Therapeutic Options in Leukemia Metabolism Research
edited by
submission deadline 30 Sep 2024 | Viewed by 134 | Submission Open
Keywords: acute myeloid leukemia (AML); chronic myeloid leukemia (CML); acute lymphocytic leukemia (ALL); chronic lymphocytic leukemia (CLL); tumor metabolism; metabolic rewiring
(This special issue belongs to the Section Molecular Medicine)
Biomolecules in Forensic Molecular Genetics
edited by
submission deadline 30 Sep 2024 | Viewed by 134 | Submission Open
Keywords: forensic; DNA; RNA; protein; mtDNA; epigenetics; microbiome
(This special issue belongs to the Section Molecular Genetics)
Molecular and Cellular Mechanisms of Megakaryocyte and Platelet Production
edited by Pedro J. Real and
submission deadline 30 Sep 2024 | Viewed by 134 | Submission Open
Keywords: megakaryocytes; platelets; omics; platelet disorders; inflammation
(This special issue belongs to the Section Cellular Biochemistry)
Recent Advances in the Structural and Functional Properties of Glutamate Dehydrogenase
edited by
submission deadline 30 Sep 2024 | Viewed by 134 | Submission Open
Keywords: glutamate dehydrogenase; GLUD1; GLUD2; structure-function relationships; neurodegenerative disorders
(This special issue belongs to the Section Enzymology)
New Insights into Kidney Disease Development and Therapy Strategies submission deadline 1 Oct 2024 | 3 articles | Viewed by 2617 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
Recent Advances in the Role of Translation Machinery and Translational Control in the Cardiovascular System
edited by Peng Yao and
submission deadline 1 Oct 2024 | Viewed by 239 | Submission Open
Keywords: translational control; translation machinery; RNA-binding protein; non-coding RNA
Molecular Advances in Rett Syndrome and Other Chromatin Related Disorders
edited by and Salvatore Fioriniello
submission deadline 1 Oct 2024 | Viewed by 180 | Submission Open
Keywords: Rett syndrome and other chromatin disorders; epigenetic diseases; molecular alterations in Rett syndrome and other chromatin diseases; novel genes associated with chromatin disorders; MeCP2-mediated molecular mechanisms; roles of epigenetic modulators in chromatin-related diseases; preclinical studies for chromatin diseases; novel diagnostic; prognostic and therapeutic approaches for chromatin disorders
(This special issue belongs to the Section Molecular Medicine)
Molecular Pathology, Diagnostics and Therapeutics of Retinal Diseases
edited by
submission deadline 15 Oct 2024 | 6 articles | Viewed by 16589 | Submission Open
Keywords: retina; macula; macular edema; inflammatory mediators; optical coherence tomography; retinal imaging; biochemical marker; biomarker; pharmacological targeting
(This special issue belongs to the Section Molecular Medicine)
Muscular Dystrophy: From Molecular Basis to Therapies submission deadline 15 Oct 2024 | 5 articles | Viewed by 15239 | Submission Open
Keywords: muscular dystrophies; muscle regeneration; extracellular matrix; satellite cells; therapeutic approaches; animal models; clinical trials
(This special issue belongs to the Section Molecular Biology)
Mechanisms and Kinetics of Interactions of Biomolecules at Interfaces II submission deadline 15 Oct 2024 | 4 articles | Viewed by 7172 | Submission Open
Keywords: biomolecule adsorption; kinetics of biomolecule adsorption; mechanisms of biomolecule deposition; interactions of biomolecules; techniques for the detection of biomolecules at solid substrates; interactions of proteins with biomolecules/biopolymers; protein and biomolecule systems; protein and biomolecule complexes
(This special issue belongs to the Section Biological and Bio- Materials)
Antibiotic Resistance Mechanisms and Their Potential Solutions
edited by Sung-Pin Tseng, and
submission deadline 15 Oct 2024 | 3 articles | Viewed by 5080 | Submission Open
Keywords: antibiotic resistance; antimicrobial development; molecular mechanism; priority for antibiotics; newly therapeutic approach
(This special issue belongs to the Section Molecular Biology)
TRP Channels in Cardiovascular and Inflammatory Disease
edited by and Soraia Katia Pereira Costa
submission deadline 15 Oct 2024 | 3 articles | Viewed by 3962 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
New Insights into Cardiovascular Immunology
edited by Susanne Sattler, Pilar Martín and Stephen Malin
submission deadline 15 Oct 2024 | 1 articles | Viewed by 2362 | Submission Open
Keywords: inflammation; autoimmunity; atherosclerosis; myocarditis; heart failure
(This special issue belongs to the Section Molecular Medicine)
Advances in Nano-Based Drug Delivery: Unveiling the Next Frontier submission deadline 15 Oct 2024 | 1 articles | Viewed by 1086 | Submission Open
Keywords: targeted drug delivery; smart nanoformulation; controlled drug release; biocompatible nanocarriers; extracellular vesicles; immunotherapy
Recent Advances in Supramolecular Motility Machinery of Microorganisms submission deadline 15 Oct 2024 | 1 articles | Viewed by 893 | Submission Open
Keywords: motor proteins; motility; taxis; force generation; signal transduction
(This special issue belongs to the Section Molecular Biophysics)
Molecular and Cell Biology in Endometriosis and Endometrial Cancer: Volume 2 submission deadline 15 Oct 2024 | 1 articles | Viewed by 449 | Submission Open
Keywords: endometriosis; endometrial cancer; ovarian cancer; molecular basis of endometriosis and endometrial cancer; single cell transcriptomics; spatial transcriptomics; multiomics; genomics; proteomics; epigenomics; metabolomics
Role of Neuroactive Steroids in Health and Disease, 2nd Volume submission deadline 15 Oct 2024 | Viewed by 148 | Submission Open
Keywords: neurosteroids; neurodegenerative disorders; psychiatric disorders; physiological effects
Bionanomaterials: Synthesis, Characterization, Toxicity and Biomedical Applications (Volume II) submission deadline 20 Oct 2024 | 5 articles | Viewed by 7280 | Submission Open
Keywords: nanoparticles; nano-alloys; graphene; nanotubes; hybrid nanomaterials; green synthesis; cytotoxicity; systemic toxicity; modulation of the biological impact; nanomaterials as diagnostic and therapeutic platforms; potential applications in medicine
(This special issue belongs to the Section Biological and Bio- Materials)
Molecular Basis of Cardiac Fibrotic Remodeling: Prognosis of Fibrosis in the Heart
edited by and
submission deadline 20 Oct 2024 | 3 articles | Viewed by 6324 | Submission Open
Keywords: cardiac fibrosis; atrial fibrotic remodeling; cardiac repair; extracellular matrix remodeling; differentiation of fibroblasts to myofibroblasts; activation of cardiac fibroblasts
(This special issue belongs to the Section Molecular Biology)
Gametogenesis and Gamete Interaction, 2nd Edition
edited by
submission deadline 26 Oct 2024 | Viewed by 64 | Submission Open
Keywords: gametogenesis and meiosis; sperm attraction and activation; gamete interaction and recognition; species specificity and self/nonself-recognition in hermaphrodites; acrosome reaction sperm penetration of egg coat; gamete membrane fusion; polyspermy block; egg activation
(This special issue belongs to the Section Molecular Reproduction)
NAD Metabolism in Physiology and Pathology
edited by Mathias Ziegler
submission deadline 30 Oct 2024 | 1 articles | Viewed by 1163 | Submission Open
Keywords: NAD; ADP-ribosylation; sirtuins; redox homeostasis; NAD glycohydrolases
(This special issue belongs to the Section Molecular Medicine)
Development, Characterization, and Application of Bioactive Peptides, Diagnostic Biomarkers, and Pharmaceutical Proteins
edited by and Ji-Hun Kim
submission deadline 31 Oct 2024 | 10 articles | Viewed by 14552 | Submission Open
Keywords: bioactive peptides; biomarker proteins; pharmaceutical proteins; protein engineering; protein/peptide nanoparticles; protein/peptide production process; enzymology; antibody technology
(This special issue belongs to the Section Biomacromolecules: Proteins)
Insights of Innate Immunology into Inflammation and Infections
edited by , Bo Liu and
submission deadline 31 Oct 2024 | 4 articles | Viewed by 10532 | Submission Open
Keywords: innate immunity; innate immune cells; inflammation; infection
(This special issue belongs to the Section Molecular Medicine)
DNA Damage and DNA Repair in Cancer submission deadline 31 Oct 2024 | 6 articles | Viewed by 10048 | Submission Open
Keywords: DNA damage; DNA repair; cancer; therapy; radiation biology; systems biology
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
In Silico Drug Design and Discovery: Big Data for Small Molecule Design 2nd Edition submission deadline 31 Oct 2024 | 4 articles | Viewed by 7350 | Submission Open
Keywords: drug discovery; medicinal chemistry; chemoinformatics; bioinformatics; machine learning; deep learning
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Biomarkers in Oral Diseases 2.0 submission deadline 31 Oct 2024 | 4 articles | Viewed by 7338 | Submission Open
Keywords: oral cancer; oral carcinogenesis; oral potentially malignant disorders; oral manifestations of autoimmune mediated diseases; periodontal diseases; head and neck pathology
(This special issue belongs to the Section Molecular Biomarkers)
Skeletal Muscle Homeostasis and Regeneration
edited by
submission deadline 31 Oct 2024 | 5 articles | Viewed by 6866 | Submission Open
Keywords: skeletal muscle; homeostasis; regeneration; satellite cells; fiber type
(This special issue belongs to the Section Molecular Medicine)
Recent Advances in Laccases and Laccase-Based Bioproducts submission deadline 31 Oct 2024 | 4 articles | Viewed by 6734 | Submission Open
Keywords: laccase; application; heterologous expression; bioproducts; laccase engineering
(This special issue belongs to the Section Enzymology)
Identification and Characterization of Receptors for Bacillus thuringiensis Pesticidal Toxins submission deadline 31 Oct 2024 | 5 articles | Viewed by 5027 | Submission Open
Keywords: mode of action; bacterial toxins; cry proteins; Vip proteins; insecticidal proteins; functional assays; binding to receptors; cross-resistance; Bacillus thuringiensis; resistance mechanism
(This special issue belongs to the Section Molecular Biology)
Biomarkers for Vascular Disease II
edited by Ori D. Rotstein, and Muzammil Syed
submission deadline 31 Oct 2024 | 3 articles | Viewed by 4239 | Submission Open
Keywords: peripheral arterial disease; abdominal aortic aneurysm; carotid artery stenosis; biomarkers
(This special issue belongs to the Section Molecular Biomarkers)
Molecular Interventions in Ocular Disorders
edited by
submission deadline 31 Oct 2024 | 2 articles | Viewed by 3436 | Submission Open
Keywords: molecular interventions; innovative therapies; surgical techniques; gene therapy; regenerative medicine; targeted therapies; customized treatment
(This special issue belongs to the Section Molecular Medicine)
Applications of Mesenchymal Stem/Stromal Cells in Immuno-Oncology Therapy and The Priming Ways to Boost Their Functions
edited by , Hassan Fahmi and
submission deadline 31 Oct 2024 | 3 articles | Viewed by 2566 | Submission Open
Keywords: immuno-oncology; immunotherapy; stem/stromal cells; gene regulation; epigenetics; immunoregulatory functions; priming procedures
(This special issue belongs to the Section Molecular Medicine)
Neurodevelopmental Disorders: Genetic Studies and Therapeutic Strategies
edited by and Bruno Bontempi
submission deadline 31 Oct 2024 | 1 articles | Viewed by 2260 | Submission Open
Keywords: mouse models; Autism Spectrum disorder; transgenic rodents; pharmacological treatments; gene-environment interactions; neurodevelopmental disorders; rare diseases
(This special issue belongs to the Section Molecular Genetics)
Viral Respiratory Infection including COVID-19: From Molecular Mechanisms to Therapies Strategies submission deadline 31 Oct 2024 | 1 articles | Viewed by 1336 | Submission Open
Keywords: post-COVID; syndrome; COVID-19; viral respiratory infections; SARS-CoV-2
(This special issue belongs to the Section Molecular Medicine)
From Dietary Polyphenols to Senolytic Supplements in the Search of the “Fountain of Youth”—Honorary Special Issue Commemorating the Pioneering Work of Prof. Giulio Maria Pasinetti submission deadline 31 Oct 2024 | Viewed by 1302 | Submission Open
Keywords: Alzheimer’ s disease; supplements; amyloid-β ; tau; microglia; immunomodulator  
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Diabetic Retinopathy: From Pathophysiology to Therapeutic Perspectives
edited by Annayya R. Aroor, and Dean P. Hainsworth
submission deadline 31 Oct 2024 | 1 articles | Viewed by 1274 | Submission Open
Keywords: diabetic retinopathy; microvascular injury; neuronal dysfunction; mitochondrial dysfunction; oxidative stress; inflammation; biomarkers; signaling pathways; pharmacological interventions; anti-vegf; gene therapy; stem cell-based therapies; prevention strategies; patient education programs; patient-centered care
(This special issue belongs to the Section Molecular Medicine)
Advances in Cardiometabolic Health submission deadline 31 Oct 2024 | 1 articles | Viewed by 721 | Submission Open
Keywords: obesity; cardiovascular diseases; biomarkers; lifestyle interventions; personalized medicine
(This special issue belongs to the Section Cellular Biochemistry)
Molecular Mechanisms of Viral Infections submission deadline 31 Oct 2024 | Viewed by 446 | Submission Open
Keywords: viral replication; virus evolution; immune response; antiviral strategies virus; infection; pathogenesis; virulence
(This special issue belongs to the Section Molecular Biology)
New Insights into Integrins
edited by
submission deadline 31 Oct 2024 | 1 articles | Viewed by 388 | Submission Open
Keywords: integrins; growth factors; ligands
(This special issue belongs to the Section Biological Factors)
Colorectal and Gastric Cancers: Molecular Mechanisms and Potential Biomarkers submission deadline 31 Oct 2024 | 1 articles | Viewed by 384 | Submission Open
Keywords: colorectal cancer; gastric cancer; molecular mechanism; biomarkers signalling; molecules gastrointestinal; microbiome; artificial intelligence
(This special issue belongs to the Section Molecular Biomarkers)
Aldo-Keto Reductases: Functions, Molecular Mechanisms and Regulation submission deadline 31 Oct 2024 | Viewed by 357 | Submission Open
Keywords: aldo-keto reductases; NAD(P)(H)-dependent oxidoreductases; diabetes; inflammation; detoxification
(This special issue belongs to the Section Enzymology)
New Insights into Cancer Genomics
edited by
submission deadline 31 Oct 2024 | Viewed by 275 | Submission Open
Keywords: carcinogenesis; cancer genomics; DNA damage; DNA repair pathway; DNA lesion; genomic instability
(This special issue belongs to the Section Molecular Medicine)
New Insights into Molecular Mechanisms and Therapeutics for Malaria
edited by
submission deadline 31 Oct 2024 | Viewed by 256 | Submission Open
Keywords: antimalarial resistance; drug discovery; malaria epidemiology; diagnostic tools; malaria pathophysiology
(This special issue belongs to the Section Molecular Medicine)
Neuron–Astrocyte Interactions in Neurological Function and Disease
edited by Micaela Zonta and Alessandro Di Spiezio
submission deadline 31 Oct 2024 | Viewed by 233 | Submission Open
Keywords: astrocytes; neuron-astrocyte communication; brain function; neurological disease
(This special issue belongs to the Section Cellular Biochemistry)
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