How to Properly Diagnose and Treat Immune-Related Adverse Events during Immunotherapy in Patients with Cancer: Discussion between Specialists
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Immunology and Immunotherapy".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 17810
Special Issue Editors
Interests: cancer; vaccines; immunotherapy; viral infection; microbiome
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Immune checkpoint inhibitors (ICIs) are a milestone in the management of cancer patients. ICIs are able to promote the restoration of T-cell function and immune surveillance against cancer cells. Due to this biological mechanism, patients may develop immune-related adverse events (irAEs). The timing of onset and severity of these irAEs can be very different depending on the type and pattern of ICIs (alone or in combination) and the susceptibility of patients. Nowadays, oncologists have to promptly recognize and manage various types of irAEs. These irAEs can be severe and associated with life-threatening conditions. They require an early diagnosis and specific treatments, highlighting the need to build (or implement) a network of multidisciplinary collaborations between the various oncologists and various healthcare specialists. In the present Special Issue, “How to Properly Diagnose and Treat Immune-Related Adverse Events during Immunotherapy in Patients with Cancer: Discussion Between Specialists”, we encourage submissions that deal with the following topics:
- Immune checkpoint inhibitors and infectious complications;
- Rare irAEs (Haematological, cardiac and neurological toxicities);
- Renal dysfunction and long-term effects of ICIs on kidney function;
- irAEs and microbiota;
- irAES and vaccines;
- Identification of non-invasive diagnostic and predictive biomarkers of these IRAEs.
Dr. Angioletta Lasagna
Dr. Paolo Sacchi
Guest Editors
Manuscript Submission Information
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Keywords
- ICIs
- immune-related adverse effects (irAEs)
- infectious complications
- immune reconstitution
- inflammatory syndrome (IRIS)
- microbiota
- vaccines
- molecular mimicry
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