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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Image Assisted High Precision Radiation Oncology

edited by Christopher Njeh and Senthamizhchelvan Srinivasan

submission deadline 25 Jul 2026 | 2 articles | Viewed by 1902 | Submission Open

Keywords: image-guided radiation therapy (IGRT); MR-guided radiation therapy (MRgRT); adaptive radiation therapy (ART); radiomics and AI in imaging; multi-modal imaging (CT; MRI; PET); treatment planning and verification; real-time tracking and motion management; stereotactic radiotherapy (SBRT/SRS); imaging biomarkers; dose accumulation and image registration

(This special issue belongs to the Section Methods and Technologies Development)

Updates on Urothelial Carcinoma

edited by

Toyonori Tsuzuki

and Yasmin Abu-Ghanem

submission deadline 25 Jul 2026 | 1 articles | Viewed by 1023 | Submission Open

Keywords: urothelial carcinoma; systemic therapy; molecular biomarkers; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Gene Regulation of Immune Checkpoints in Cancer Immunotherapy

edited by Stamatios Theocharis,

Apostolos Zaravinos

and

Maria-Ioanna Christodoulou

submission deadline 25 Jul 2026 | Viewed by 165 | Submission Open

Keywords: immune checkpoint; gene regulation; immune evasion; epigenetic– immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Neoadjuvant Immunotherapy in Genitourinary Tumors (2nd Edition)

edited by

Antonio Tufano

, Nadia Cordua and

Antonio Giordano

submission deadline 26 Jul 2026 | Viewed by 260 | Submission Open

Keywords: immunotherapy; immune checkpoint inhibitor; bladder cancer; urothelial cancer; kidney cancer; renal cell carcinoma; prostate cancer; testicular cancer; penile cancer; adrenocortical carcinoma

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Advances in Lung Ultrasound in Cancer Patients

edited by Helmut Prosch and

Ehsan Safai Zadeh

submission deadline 30 Jul 2026 | 6 articles | Viewed by 8682 | Submission Open

Keywords: lung ultrasound; neoplastic pleuro-pulmonary lesions; lung cancer; oncologic imaging; ultrasound; CEUS; elastography

(This special issue belongs to the Section Methods and Technologies Development)

Machine Learning and Artificial Intelligence in Cancer Diagnostic and Monitoring

edited by

Junfeng Wang

submission deadline 30 Jul 2026 | 4 articles | Viewed by 5839 | Submission Open

Keywords: machine learning; artificial intelligence; implementation; fairness; uncertainty

(This special issue belongs to the Section Methods and Technologies Development)

Precision Medicine and Targeted Therapies in Neuroblastoma

edited by

Nilay Shah

submission deadline 30 Jul 2026 | 2 articles | Viewed by 4297 | Submission Open

Keywords: pediatric oncology; solid tumors; targeted therapies; biomarkers of response; novel combination therapies; tumor microenvironment; integrative diagnostics; theranostics; telomere maintenance mechanisms; neuroblastoma

(This special issue belongs to the Section Clinical Research of Cancer)

Cancer Pain: Advances in Pathophysiology and Management

edited by

Giustino Varrassi

and

Matteo Luigi Giuseppe Leoni

submission deadline 30 Jul 2026 | 1 articles | Viewed by 3571 | Submission Open

Keywords: cancer pain; mixed pain; pathophysiology; sensitization; multimodal analgesia; interventional management

Ovarian Cancer: Pathogenesis, Molecular Mechanism and Opportunities for Interventions

edited by

Apriliana Kartikasari

submission deadline 30 Jul 2026 | 1 articles | Viewed by 2715 | Submission Open

Keywords: ovarian cancer; pathogenesis; therapy; biomarkers; molecular

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Multidisciplinary Approach to Bladder Cancer Treatment and Care

edited by Bente Thoft Jensen and

Susanne Vahr Lauridsen

submission deadline 30 Jul 2026 | 2 articles | Viewed by 1749 | Submission Open

Keywords: non-muscle-invasive bladder cancer; muscle-invasive bladder cancer; health-related quality of life; nutrition; prehabilitation; sexual health; nursing leadership; implementation; new technologies

(This special issue belongs to the Section Cancer Therapy)

The Evolution of Minimally Invasive Surgery in Hepatobiliary Pancreatic Cancers

edited by Asmus Heumann

submission deadline 30 Jul 2026 | 1 articles | Viewed by 597 | Submission Open

Keywords: minimally invasive surgery; biliary tract cancer; perhilar carcinoma; pancreatic cancer; liver transplantation

(This special issue belongs to the Section Cancer Therapy)

Cutting-Edge Nanomedicine Advancements in Cancer Disease

edited by

Ana Isabel Torres-Suárez

and

Ana Isabel Fraguas-Sánchez

submission deadline 30 Jul 2026 | Viewed by 479 | Submission Open

Keywords: active targeting; breast cancer; drug delivery; liposomes; lung cancer; metallic nanoparticles; polymeric nanoparticles; theragnostic

(This special issue belongs to the Section Methods and Technologies Development)

Flow Cytometry and Molecular Studies in Hematological Malignancies

edited by Kirill A. Lyapichev

submission deadline 30 Jul 2026 | Viewed by 384 | Submission Open

Keywords: flow cytometry; molecular studies; hematological neoplasms; lymphoma; leukemia

(This special issue belongs to the Section Molecular Cancer Biology)

Cellular Plasticity, Metabolic Adaptations and Therapeutic Strategies in Breast Cancer

edited by

Kunwar Somesh Vikramdeo

submission deadline 30 Jul 2026 | Viewed by 376 | Submission Open

Keywords: breast cancer; cellular plasticity; metabolic reprogramming; tumor microenvironment; therapy resistance; epithelial– mesenchymal transition (EMT); cancer stem cells; redox metabolism; mitochondrial pathways; targeted therapy

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Surgical Management of Ovarian Cancer

edited by Lina Salman

submission deadline 30 Jul 2026 | Viewed by 275 | Submission Open

Keywords: ovarian cancer; surgical management; complications; HIPEC; survival

(This special issue belongs to the Section Clinical Research of Cancer)

Resection and Reconstruction for Breast Cancer

edited by Radoslaw Tarkowski and

Gilles Houvenaeghel

submission deadline 30 Jul 2026 | Viewed by 254 | Submission Open

Keywords: oncoplastic breast surgery; breast reconstruction; breast cancer

(This special issue belongs to the Section Clinical Research of Cancer)

The New Era of Esophageal Cancer Treatment: Advances in Combination Therapy

edited by

Elena Mazza

submission deadline 30 Jul 2026 | Viewed by 194 | Submission Open

Keywords: esophageal cancer; combination therapy; immunotherapy; targeted agents; Pd-L1; chemotherapy; radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Emerging Research on Primary Brain Tumors

edited by Jacob S Young and Mitchel S. Berger

submission deadline 31 Jul 2026 | 6 articles | Viewed by 24021 | Submission Open

Keywords: molecular biomarkers; drug delivery; immunotherapy; personalized medicine; targeted therapies; glioma

(This special issue belongs to the Section Cancer Therapy)

Advancements in Preclinical Models for Solid Cancers

edited by

Ewa Krawczyk

and Paula Dobosz

submission deadline 31 Jul 2026 | 11 articles | Viewed by 23668 | Submission Open

Keywords: solid cancers; preclinical cancer models; in vitro cancer models; in vivo cancer models; translational cancer research; strengths and limitations of preclinical cancer models

(This special issue belongs to the Section Clinical Research of Cancer)

Systematic Reviews and Meta-Analyses of Genitourinary Cancers (2nd Edition)

edited by

Giorgio Treglia

and Ursula Maria Vogl

submission deadline 31 Jul 2026 | 6 articles | Viewed by 20713 | Submission Open

Keywords: systematic review; meta-analysis; oncology; genitourinary cancers; diagnosis; therapy

(This special issue belongs to the Section Systematic Review or Meta-Analysis in Cancer Research)

Robotic Surgery in Colorectal Cancer

edited by James Chi Yong Ngu

submission deadline 31 Jul 2026 | 5 articles | Viewed by 19144 | Submission Open

Keywords: robotic surgery; colorectal cancer; minimally invasive surgery; therapeutic endoscopy; laparoscopy

(This special issue belongs to the Section Clinical Research of Cancer)

Novel Advances in the Molecular Understanding of Myeloproliferative Neoplasms (MPNs)

edited by Wei Chen, Fei Li and

Qiang Jeremy Wen

submission deadline 31 Jul 2026 | 5 articles | Viewed by 18294 | Submission Open

Keywords: MPNs; ET; PV; PMF; post-PV-MF; post-ET-MF; MDS/MPN; JAK2

(This special issue belongs to the Section Molecular Cancer Biology)

The Tumor Microenvironment: Interplay Between Immune Cells

edited by Jared Rowe and Kristen E. Pauken

submission deadline 31 Jul 2026 | 6 articles | Viewed by 15981 | Submission Open

Keywords: tumor immune microenvironment; metabolic microenvironment; immune cells

(This special issue belongs to the Section Tumor Microenvironment)

Radiosurgery for Brain Tumors

edited by Anna Petoukhova

submission deadline 31 Jul 2026 | 5 articles | Viewed by 13331 | Submission Open

Keywords: radiosurgery with photons and protons; stereotactic radiosurgery (SRS); brain tumors; gliomas; meningioma; pituitary adenoma; magnetic resonance imaging (MRI); magnetic resonance linac (MRL)

(This special issue belongs to the Section Cancer Therapy)

Advances in Ovarian Cancer Research and Treatment: 2nd Edition

edited by

Maria Barbolina

submission deadline 31 Jul 2026 | 7 articles | Viewed by 12106 | Submission Open

Keywords: ovarian carcinoma metastasis; mechanisms of dissemination; chemotherapy resistance; novel treatments and therapeutic approaches; novel molecular targets

(This special issue belongs to the Section Cancer Therapy)

Evolving Understanding of the Epidemiology of Thyroid Cancer

edited by

Marco Capezzone

and

Anello Marcello Poma

submission deadline 31 Jul 2026 | 3 articles | Viewed by 11686 | Submission Open

Keywords: thyroid cancer; epidemiology; incidence; time trends; mortality

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Oral Cancer: The Latest Advances in Clinical and Basic Research (Second Edition)

edited by

Kenji Yamagata

and Fumihiko Uchida

submission deadline 31 Jul 2026 | 6 articles | Viewed by 10919 | Submission Open

Keywords: oral cancer; clinical research; basic research; surgery; radiotherapy; chemotherapy; molecular biology; immune checkpoint inhibitor

(This special issue belongs to the Section Clinical Research of Cancer)

The Roles of Deep Learning in Cancer Radiotherapy

edited by Zhen Tian

submission deadline 31 Jul 2026 | 6 articles | Viewed by 9301 | Submission Open

Keywords: radiotherapy; deep learning; artificial Intelligence; tumor detection; image segmentation; treatment planning; outcome prediction; radiomics

(This special issue belongs to the Section Cancer Informatics and Big Data)

Clinical Treatment and Prognosis of Breast Cancer

edited by Roxana Popescu and

Ionut Marcel Cobec

submission deadline 31 Jul 2026 | 4 articles | Viewed by 8695 | Submission Open

Keywords: breast cancer; targeted therapy; personalized therapy; alternative approach; tumor biology; gynecologic oncology

(This special issue belongs to the Section Clinical Research of Cancer)

Clinical Trials and Outcomes for Non-Small Cell Lung Cancer

edited by

Ana Rodrigues

and

António Araújo

submission deadline 31 Jul 2026 | 7 articles | Viewed by 8440 | Submission Open

Keywords: non-small cell lung cancer; oncogenic alterations; clinical trial; systemic therapy; targeted therapy; immunotherapy; radiotherapy; real-world data; surgery; drug development

(This special issue belongs to the Section Clinical Research of Cancer)

Cancer Metastasis in 2025–2026

edited by

Lance A. Liotta

submission deadline 31 Jul 2026 | 5 articles | Viewed by 8132 | Submission Open

Keywords: immunotherapy; tumor suppression; cancer metastasis; invasion

(This special issue belongs to the Section Cancer Metastasis)

Survivorship Following Childhood, Adolescent, and Young Adult Cancer

edited by Magdalena Balcerek and Judith Gebauer

submission deadline 31 Jul 2026 | 6 articles | Viewed by 7620 | Submission Open

Keywords: cancer survivorship; late effects; long-term follow-up care; supportive care; health prevention and promotion

(This special issue belongs to the Section Pediatric Oncology)

Circulating Tumor Cells (CTCs) and the Implementation of Liquid Biopsy (2nd Edition)

edited by

Dario Marchetti

submission deadline 31 Jul 2026 | 4 articles | Viewed by 6941 | Submission Open

Keywords: liquid biopsy; metastatic biomarkers; CTCs isolation technologies; tumor heterogeneity; clinical CTC applications

(This special issue belongs to the Section Tumor Microenvironment)

The Emerging Role of Multiplexed Imaging for Cancer Diagnosis and Therapy (2nd Edition)

edited by

Li Liu

and

Yicheng Ni

submission deadline 31 Jul 2026 | 4 articles | Viewed by 6003 | Submission Open

Keywords: multiplexed imaging; cancer diagnosis; molecular imaging; novel contrast agents; targeted radionuclide tracers theragnostics; personalized cancer therapy; therapeutic monitoring; imaging biomarkers; clinical translation

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Circulating Tumour DNA and Liquid Biopsy in Oncology

edited by

Yafeng Ma

and Kevin Spring

submission deadline 31 Jul 2026 | 5 articles | Viewed by 5994 | Submission Open

Keywords: cell-free DNA; circulating tumour DNA; liquid biopsy; mutation status; tumour mutational burden; methylation detection; fragmentomics; minimal residual disease; early detection

(This special issue belongs to the Section Cancer Biomarkers)

Updates on Imaging of Common Urogenital Neoplasms—2nd Edition

edited by Athina C Tsili

submission deadline 31 Jul 2026 | 5 articles | Viewed by 4723 | Submission Open

Keywords: urogenital neoplasms; renal cell carcinoma; prostatic neoplasms; urinary bladder neoplasms; testicular neoplasms; uterine neoplasms; ovarian neoplasms; ultrasonography; computed tomography; magnetic resonance imaging

(This special issue belongs to the Section Methods and Technologies Development)

New Trends in Urologic Oncology: Surgical Treatments, Robotics, Biomarkers, Diagnostic Tools, and Innovative Therapies

edited by Alessandro Uleri and

Roberto Contieri

submission deadline 31 Jul 2026 | 4 articles | Viewed by 4247 | Submission Open

Keywords: prostate cancer; renal cancer; bladder cancer; UTUC; testicular cancer; penile cancer; biomarkers

(This special issue belongs to the Section Clinical Research of Cancer)

Novel Approaches in the Management of Gynecological Cancers

edited by

Mikel Gorostidi

Martina Aida Angeles

and

Ignacio Zapardiel

submission deadline 31 Jul 2026 | 4 articles | Viewed by 3899 | Submission Open

Keywords: gynecological cancer; ovarian cancer; endometrial cancer; cervical cancer; vulvar cancer; surgical management; clinical management

(This special issue belongs to the Section Cancer Therapy)

Nutrition in Survivors with Advanced Cancer: The Role of Appetite, Muscle Wasting, Obesity, and Altered Body Composition

edited by Egidio Del Fabbro

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3752 | Submission Open

Keywords: advanced cancer; nutrition; wasting; body composition; multimodal

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Pituitary Tumors: Clinical and Surgical Challenges

edited by

Michal Hlavac

and

Andrej Pala

submission deadline 31 Jul 2026 | 1 articles | Viewed by 3495 | Submission Open

Keywords: pituitary; neuroendocrine tumors; transsphenoidal endoscopic surgery; MRI imaging; quality of life

(This special issue belongs to the Section Clinical Research of Cancer)

Epstein-Barr Virus-Associated Cancers: From Pathogenesis to Treatment (2nd Edition)

edited by

Kwok-Wai Lo

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3391 | Submission Open

Keywords: EBV; lymphomas; Burkitt lymphoma; Hodgkin lymphoma; NK/T cell lymphoma; nasopharyngeal carcinoma; gastric cancer; biomarkers; immunotherapy; targeted therapy

(This special issue belongs to the Section Infectious Agents and Cancer)

Novel Insights into Glioblastoma and Brain Metastases (2nd Edition)

edited by

Sanjay K. Srivastava

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3380 | Submission Open

Keywords: glioblastoma; brain metastasis; surgery; radiation; chemotherapy; blood– brain barrier; immunotherapy; novel targets; oncogenes; tumor heterogeneity; drug discovery

(This special issue belongs to the Section Cancer Metastasis)

Lung Cancer—Advances in Therapy and Prognostic Prediction

edited by Chinmay T. Jani and Estelamari Rodríguez

submission deadline 31 Jul 2026 | 3 articles | Viewed by 2935 | Submission Open

Keywords: lung cancer; biomarkers; targeted therapies; immunotherapy; precision medicine

(This special issue belongs to the Section Cancer Biomarkers)

Radiosensitivity and Radiotoxicity in Cancer

edited by

Alexandros Georgakilas

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2627 | Submission Open

Keywords: radiation therapy; clinical outcome; radiosensitivity; radiotoxicity; biomarkers; bioinformatics; systems biology

(This special issue belongs to the Section Methods and Technologies Development)

Prostate Cancer Metastasis—Diagnosis and Treatment

edited by Arnulf Stenzl

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2306 | Submission Open

Keywords: prostate cancer; metastasis; hormone-sensitive; castration-resistant prostate cancer; imaging; PSMA; ligand therapy; sequence; oligometastatic; biomarker

(This special issue belongs to the Section Cancer Metastasis)

Biologic Advancements in Childhood and Adolescent Cancers: From Disease Mechanisms to Precision Therapies

edited by

Emmanouel Hatzipantelis

and Eleni Tsotridou

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2285 | Submission Open

Keywords: pediatric oncology; precision therapies; molecular vulnerabilities; biomarker-driven trials; disease mechanisms

(This special issue belongs to the Section Pediatric Oncology)

Hybrid Molecular Imaging Approaches in Cancer: PET/CT, PET/MRI, and Beyond

edited by

Luca Urso

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2168 | Submission Open

Keywords: PET/CT; PET/MRI; hybrid molecular imaging; radiomics and artificial intelligence; conventional PET Radiotracers; emerging PET Radiotracers; cancer imaging

(This special issue belongs to the Section Methods and Technologies Development)

Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) in Patients with Cancers

edited by Caterina Alati and Martina Pitea

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2115 | Submission Open

Keywords: hematopoietic stem cell; hematologic malignancies; transplantation; immunotherapy

(This special issue belongs to the Section Transplant Oncology)

Oncological Healthcare: Emergency and Supportive/Palliative Approaches

edited by Ahmed Elsayem and Pavitra Parimala Krishnamani

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1916 | Submission Open

Keywords: supportive oncology; palliative care; symptom distress; emergency medicine; critical care; goals of care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Neoadjuvant Therapy for Urologic Cancer

edited by Marlon Perera and David Chen

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1865 | Submission Open

Keywords: urologic oncology; neoadjuvant therapy; treatment; improved survival

(This special issue belongs to the Section Cancer Therapy)

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