Special Issues

Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cell Biology of Cancer Invasion
edited by
submission deadline 15 Jan 2025 | 5 articles | Viewed by 7933 | Submission Open
Keywords: invasion; metastasis; intravasation; extravasation; invadopodia; tumor microenvironment; epithelial– mesenchymal transition; cell migration; cytoskeleton; cell adhesion; extracellular matrix; matrix metalloprotease; cancer-associated fibroblast; tumor-associated macrophage
(This special issue belongs to the Section Molecular Cancer Biology)
Thyroid Cancer: Incidence and Risk Factors submission deadline 15 Jan 2025 | 5 articles | Viewed by 6725 | Submission Open
Keywords: thyroid cancer incidence; epidemiology; risk factors; environment; molecular epidemiology; thyroid cancer and radiation; thyroid cancer and pollutants; thyroid cancer and lifestyle; thyroid nodules and thyroid cancer
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Clinical and Research Progress in the Resection of Gastro-Esophageal Cancer
edited by Biniam Kidane
submission deadline 15 Jan 2025 | 4 articles | Viewed by 4173 | Submission Open
(This special issue belongs to the Section Clinical Research of Cancer)
Lung Cancer Proteogenomics: New Era, New Insights submission deadline 15 Jan 2025 | 1 articles | Viewed by 3194 | Submission Open
Keywords: lung cancer; genomic; transcriptomic; bioinformatic tools; multi-omics
(This special issue belongs to the Section Molecular Cancer Biology)
Novel Therapeutic Approaches for Cancer Treatment submission deadline 15 Jan 2025 | 2 articles | Viewed by 2748 | Submission Open
Keywords: cancer; small molecules; epigenetic drugs; drug delivery system; targeted therapy; personalized medicine; photodynamic therapy; photothermal therapy; sonodynamic therapy; drug repurposing; combination therapy
(This special issue belongs to the Section Cancer Therapy)
Treatment of Peripheral T-cell Lymphomas
edited by
submission deadline 15 Jan 2025 | 2 articles | Viewed by 2153 | Submission Open
Keywords: T-cell lymphoma; PTCL; molecular targets; targeted therapy; immunotherapy; combination therapy; biomarker
(This special issue belongs to the Section Tumor Microenvironment)
New Therapeutic Strategies of Radioresistant Tumours by Radiosensitization submission deadline 15 Jan 2025 | 1 articles | Viewed by 1666 | Submission Open
Keywords: chemo-radiation-resistant tumors; radiosensitizers; biomarkers; mechanisms of radioresistance; tumor drug radiosensitizers
(This special issue belongs to the Section Cancer Therapy)
Emerging Role of Exosomes in Comorbidity-Associated Cancer Progression
edited by Gatikrushna Panigrahi
submission deadline 15 Jan 2025 | Viewed by 366 | Submission Open
Keywords: exosomes; comorbidity; cancer; obesity; diabetes; stress; dysbiosis; metastasis
(This special issue belongs to the Section Tumor Microenvironment)
Advances in Systemic Therapy and Radiotherapy for the Treatment of Lung Cancer
edited by Gaurav Marwaha
submission deadline 15 Jan 2025 | Viewed by 304 | Submission Open
Keywords: chemoradiation; targeted therapy; immunotherapy; oligometastases; SBRT; biomarkers; NSCLC; small-cell lung cancer; PCI
(This special issue belongs to the Section Cancer Therapy)
Gastrointestinal and Its Associated Malignancies: Diagnosis, Targets and Therapies
edited by Ganji P. Nagaraju and
submission deadline 15 Jan 2025 | Viewed by 252 | Submission Open
Keywords: GI cancers; oncogenesis; diagnosis; target identification; biomarkers; therapy
(This special issue belongs to the Section Cancer Therapy)
Hypoxic Signaling: Relation to Cancer Progression and Cancer Stem Cell Regulation
edited by
submission deadline 15 Jan 2025 | Viewed by 182 | Submission Open
Keywords: HIF-1α ; HIF-2α ; cancer stem cells; treatment resistance
(This special issue belongs to the Section Molecular Cancer Biology)
Recent Advances in Non-muscle Invasive Bladder Cancer
edited by Paul L. Crispen
submission deadline 17 Jan 2025 | Viewed by 410 | Submission Open
Keywords: non-muscle invasive bladder cancer; adjuvant therapy; surveillance; BCG refractory; intravesical therapy
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
The Role of Epithelial-Mesenchymal Transition in Therapies Resistance and Cancer Metastasis
edited by Pierre Savagner
submission deadline 19 Jan 2025 | 1 articles | Viewed by 1924 | Submission Open
Keywords: epithelial-mesenchymal transition; plasticity; resistance; immune response; stemness; invasion; metabolism; metastasis; development
(This special issue belongs to the Section Cancer Metastasis)
New Findings in Targeting Cancer Proteins submission deadline 20 Jan 2025 | 5 articles | Viewed by 11861 | Submission Open
Keywords: monoclonal antibodies; protein target; immunotherapy; signaling blockade; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
Advances in the Diagnosis and Treatment of Genitourinary Cancers
edited by Piotr Radziszewski and
submission deadline 20 Jan 2025 | 5 articles | Viewed by 7520 | Submission Open
Keywords: genitourinary cancer; point-of-care diagnostics; personalized treatment; immunotherapy; treatment
(This special issue belongs to the Section Cancer Therapy)
Gynecologic Cancer: Risk Factors, Interception and Prevention
edited by Brandy Heckman-Stoddard and Goli Samimi
submission deadline 20 Jan 2025 | 4 articles | Viewed by 5456 | Submission Open
Keywords: ovarian cancer; endometrial cancer; cervical cancer; HPV; cancer prevention; gynecologic cancer risk reduction; gynecologic cancer interception; gynecologic cancer clinical trials
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Human-Papillomavirus-Related Squamous Cell Carcinoma: From Pathogenesis to Treatment submission deadline 20 Jan 2025 | 4 articles | Viewed by 4289 | Submission Open
Keywords: HPV; head and neck cancer; oropharynx; cervical cancer; genomics; metabolomics; tumor heterogeneity; microenvironment; biomarkers; epidemiology and vaccine
(This special issue belongs to the Section Cancer Therapy)
Beyond Cancer: Enhancing Quality of Life for Cancer Survivors
edited by , Maryam Lustberg and Muna Al-Khaifi
submission deadline 20 Jan 2025 | 1 articles | Viewed by 919 | Submission Open
Keywords: psychosocial oncology; cancer survivorship; long-term effects of cancer; psychoeducational interventions; innovative care models; continuing education; knowledge translation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
New Insights into Robotic Surgery for Urologic Cancer
edited by Neil Mendhiratta and
submission deadline 20 Jan 2025 | Viewed by 228 | Submission Open
Keywords: urologic oncology; genitourinary cancers; robotics; robotic surgery techniques; robotics simulation training; resident education; artificial intelligence for surgical training; surgical coaching; economics of robotic surgery; surgery financial toxicity
(This special issue belongs to the Section Cancer Therapy)
New Technologies Used to Diagnose and Treat Lymphomas
edited by
submission deadline 20 Jan 2025 | Viewed by 147 | Submission Open
Keywords: lymphoma; PET/CT; immunotherapy; sarcopenia; artificial intelligence
(This special issue belongs to the Section Cancer Therapy)
Significance of KRAS Gene Mutations in Colorectal Cancer
edited by Grazia Palomba and
submission deadline 25 Jan 2025 | 2 articles | Viewed by 2944 | Submission Open
Keywords: KRAS; colorectal cancer; target therapy; mechanism; treatment targets
(This special issue belongs to the Section Molecular Cancer Biology)
Pancreatic Cancer Treatment: Immunotherapy, Chemotherapy, Chemoradiation, and Targeted Therapy
edited by and Brett Ecker
submission deadline 25 Jan 2025 | Viewed by 392 | Submission Open
Keywords: pancreatic cancer; pancreatic ductal adenocarcinoma; actionable molecular mechanisms; translational; resection; radiation therapy; chemotherapy; immunotherapy; multimodal; personalized medicine; metastasis; systemic therapy; locoregional therapy; KRAS inhibitors; PARP inhibitors
(This special issue belongs to the Section Cancer Therapy)
Gynecological Cancer: Molecular Oncology and the Use of Emerging Technologies in Relation to Early Detection and Treatment
edited by
submission deadline 29 Jan 2025 | 7 articles | Viewed by 14645 | Submission Open
Keywords: gynaecological cancer; robotic surgery; cancer screening and detection; cellular signalling molecules; pathways cellular signalling
(This special issue belongs to the Section Methods and Technologies Development)
How COVID-19 Affects Cancer Patients
edited by
submission deadline 30 Jan 2025 | 7 articles | Viewed by 10826 | Submission Open
Keywords: COVID-19; pandemic; cancer; impact; incidence; mortality; lethality; disparities; gender
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Immunotherapy for Cancers
edited by and Barbara Bassani
submission deadline 31 Jan 2025 | 8 articles | Viewed by 13164 | Submission Open
Keywords: cancer immunotherapy; innate immunity; adaptive immunity; tumor immune microenvironment; tumor microenvironment; combination therapies; drug repurposing
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Genetics and Epigenetics of Gynecological Cancer
edited by
submission deadline 31 Jan 2025 | 7 articles | Viewed by 10410 | Submission Open
Keywords: gynecologic cancers; epigenetics; genetics; immunogenetics; predisposing mutations; biomarkers; targeted therapies; chemoresistance
(This special issue belongs to the Section Cancer Pathophysiology)
PET Imaging in Prostate Cancer submission deadline 31 Jan 2025 | 4 articles | Viewed by 10093 | Submission Open
Keywords: positron emission tomography; PET; prostate-specific membrane antigen (PSMA); theranostics; radio-ligand therapy; choline; FDG; fibroblast activation protein; FAPi; bombesin; prostate cancer; image-guided therapy; PSMA-guided therapy
(This special issue belongs to the Section Methods and Technologies Development)
Novel Approaches to Machine Learning and Artificial Intelligence in Cancer Research and Care
edited by and Christopher Gibbons
submission deadline 31 Jan 2025 | 6 articles | Viewed by 9336 | Submission Open
Keywords: machine learning; deep learning; artificial intelligence; interpretable AI; data quality; metadata; data quality; cancer; MLOps; data science; real world data
(This special issue belongs to the Section Cancer Informatics and Big Data)
Molecular Pathways in Metastasis of Lung Cancer submission deadline 31 Jan 2025 | 5 articles | Viewed by 9033 | Submission Open
Keywords: lung cancer; metastasis; signaling pathways; molecular pathology; new potential drug targets
(This special issue belongs to the Section Cancer Metastasis)
Advances in Diagnosis, Treatment and Management of Endocrine Neoplasms submission deadline 31 Jan 2025 | 5 articles | Viewed by 8752 | Submission Open
Keywords: thyroid carcinoma; thyroidectomy; parathyroid carcinoma; parathyroidectomy; adrenal gland neoplasms; adrenalectomy; neuroendocrine neoplasms
(This special issue belongs to the Section Cancer Therapy)
Predictive Biomarkers for Lung Cancer
edited by Ole Hilberg
submission deadline 31 Jan 2025 | 5 articles | Viewed by 7589 | Submission Open
(This special issue belongs to the Section Cancer Biomarkers)
Multiple Signaling Pathways in Ovarian Cancer
edited by and Ayesha B. Alvero
submission deadline 31 Jan 2025 | 4 articles | Viewed by 7038 | Submission Open
Keywords: ovarian cancer; chemoresistance; epithelial mesenchymal transformation; metastasis; signaling pathways; immune modulation
(This special issue belongs to the Section Molecular Cancer Biology)
The Emerging Role of Ion Channels in Cancer Treatment submission deadline 31 Jan 2025 | 4 articles | Viewed by 6589 | Submission Open
Keywords: ion channels; ion signaling; tumor targeting; cancer treatment; therapy resistance; precision therapy
(This special issue belongs to the Section Cancer Therapy)
Lung Cancer: From Mechanisms of Action and Risk Factors in Disease Onset to Management submission deadline 31 Jan 2025 | 7 articles | Viewed by 6475 | Submission Open
Keywords: non-small-cell lung cancer (NSCLC); small-cell lung cancer (SCLC); prevention; risk management; mechanisms
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Current Status of Neuroendocrine Tumors with a Special Focus on Diagnosis and Novel Treatments—2nd Edition
edited by
submission deadline 31 Jan 2025 | 3 articles | Viewed by 5354 | Submission Open
Keywords: neuroendocrine tumors; somatostatin analogues; PRRT; chemotherapy; 68Gallium-DOTATOC; PET; CT; targeted therapies; mTOR; inhibitors; angiogenesis
(This special issue belongs to the Section Cancer Therapy)
Cancer Drug Discovery and Development Targeting Epigenetics, Metabolism, and DNA Repair
edited by Vikas V. Dukhande and Aditi Jain
submission deadline 31 Jan 2025 | 3 articles | Viewed by 3727 | Submission Open
Keywords: apoptosis; bromodomain proteins; cancer epigenetics; cancer metabolism; DNA methylation; DNA repair; epigenetic therapeutics; histone modifications; metabolic inhibitors; Warburg effect
(This special issue belongs to the Section Cancer Drug Development)
Molecular Mechanisms and Pathophysiology of Oral Cancer submission deadline 31 Jan 2025 | 2 articles | Viewed by 3162 | Submission Open
Keywords: oral cancer; oral squamous cell carcinoma; tumor microenvironment; tumor stroma; molecular mechanism; signaling pathways
(This special issue belongs to the Section Cancer Pathophysiology)
Surgical Advances in Cancer Treatments: Exploring Innovative Approaches and Emerging Perspectives by the Italian College of Associate Professors of Surgery submission deadline 31 Jan 2025 | 4 articles | Viewed by 3110 | Submission Open
Keywords: surgical oncology; surgical innovation; image-guided surgery; robotic-assisted surgery; multidisciplinary oncology; surgical outcomes research; precision surgery; healthcare economics; surgical training and simulation
(This special issue belongs to the Section Cancer Therapy)
Pathology and Treatment of Triple-Negative Breast Cancer
edited by
submission deadline 31 Jan 2025 | 2 articles | Viewed by 3064 | Submission Open
(This special issue belongs to the Section Cancer Pathophysiology)
Surgical Management of Gastric Cancer: New Insights and Future Prospectives submission deadline 31 Jan 2025 | 2 articles | Viewed by 2998 | Submission Open
Keywords: gastric cancer; minimally invasive gastrectomy; endoscopy; robotic surgery; surgical management
(This special issue belongs to the Section Cancer Therapy)
Advances in Drug Delivery for Cancer Therapy
edited by Ashakumary Lakshmikuttyamma
submission deadline 31 Jan 2025 | 2 articles | Viewed by 2873 | Submission Open
Keywords: cancer; oncology; therapeutic target; drug resistance; immunotherapy; chemotherapy; small molecule inhibitors; drug delivery; nanoparticle
(This special issue belongs to the Section Cancer Drug Development)
Implementation of Physical Activity Promotion in Cancer Care
edited by Sarah Hardcastle
submission deadline 31 Jan 2025 | 2 articles | Viewed by 2745 | Submission Open
Keywords: physical activity; cancer survivors; behaviour change; interventions; cancer care; implementation; health
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Current Challenge and Future Advances for Lung Cancer: Genetics, Instrumental Diagnosis and Treatment 2.0 submission deadline 31 Jan 2025 | 2 articles | Viewed by 2417 | Submission Open
Keywords: lung cancer; diagnosis; treatment; therapy; cancer metastases (with an emphasis on CNS metastases); surgery; radiotherapy; chemotherapy; target therapies; immunotherapy; elderly with lung cancer; side effects; surrogate biomarkers; preclinical research; translational research
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Pediatric and Adolescent Psycho-Oncology
edited by and Amanda L. Thompson
submission deadline 31 Jan 2025 | 2 articles | Viewed by 2249 | Submission Open
Keywords: childhood cancer; adolescents; young adult; psychosocial care; emotional outcomes; survivorship; palliative care; bereavement
(This special issue belongs to the Section Pediatric Oncology)
CAR T Cells in Lymphoma and Multiple Myeloma submission deadline 31 Jan 2025 | 2 articles | Viewed by 2131 | Submission Open
Keywords: multiple myeloma; lymphoma; CAR T therapy; bi-specific antibodies; cellular therapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Image-Guided Percutaneous Laser Ablation of Solid Tumors in Urology Application
edited by and Eric M. Walser
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1948 | Submission Open
Keywords: percutaneous laser ablation; organ-sparing technique; micro-invasive procedure; FLA; TPLA; prostate; kidney
(This special issue belongs to the Section Methods and Technologies Development)
New Experimental Models in Prevalent Cancers
edited by , , Giuseppe Mirone and
submission deadline 31 Jan 2025 | 2 articles | Viewed by 1853 | Submission Open
Keywords: cell lines; 3D cultures systems and animal studies; PDXs; Drosophila melanogaster; zebrafish
(This special issue belongs to the Section Methods and Technologies Development)
Current Concept and Management of Pediatric ATRTs
edited by and Alicia C. Lenzen
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1795 | Submission Open
(This special issue belongs to the Section Pediatric Oncology)
New Approaches in Leukemia
edited by , Naveen Pemmaraju, Hsin-An Hou and Melissa Gaik Ming Ooi
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1720 | Submission Open
Keywords: acute myeloid leukemia; acute promyelocytic leukemia; acute lymphoblastic leukemia; blastic plasmacytoid dendritic cell neoplasm (BPDCN); myelodysplastic neoplasm (MDS); myeloproliferative neoplasm (MPN); chronic myeloid leukemia (CML); chronic lymphocytic leukemia (CLL)
(This special issue belongs to the Section Cancer Biomarkers)
Proteomic and Genomic Profiling of Pancreatic Cancer
edited by Aftab Alam
submission deadline 31 Jan 2025 | 2 articles | Viewed by 1677 | Submission Open
Keywords: pancreatic cancer; CART; chemotherapy; immunotherapy; PD1; biomarker; personalized medicine; secretome; genomics; proteomics; tumor microenvironment
(This special issue belongs to the Section Tumor Microenvironment)
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