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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Radiation Exposure and Cancer
edited by
submission deadline 31 Jul 2026 | Viewed by 219 | Submission Open
Keywords: radiation; cancer; epidemiology; clinical research; molecular biology; exposomics
Integrative Imaging–Genomic Modeling and AI for Precision Oncology
edited by
submission deadline 31 Jul 2026 | Viewed by 215 | Submission Open
Keywords: imaging– genomic modeling; precision oncology; machine learning; cancer imaging; digital pathology; radiogenomics; biomarker discovery; multimodal data integration
(This special issue belongs to the Section Methods and Technologies Development)
Nanomedicine for Cancer Treatment
edited by Youssef Wahib Naguib
submission deadline 31 Jul 2026 | Viewed by 214 | Submission Open
Keywords: cancer nanomedicine; CRISPR/CAS9 nanomedicine; immune checkpoint inhibitors; cancer immunotherapy; targeted therapeutics; targeted nanoparticles; cell-penetrating peptides
(This special issue belongs to the Section Cancer Drug Development)
Redefining Cancer Through Its Microenvironment: Mechanisms, Modeling, and Targeting Strategies
edited by Leandro Marcelo Martinez
submission deadline 31 Jul 2026 | Viewed by 204 | Submission Open
Keywords: tumor microenvironment; solid cancer; hematologic malignancies; tumor initiation; tumor progression; therapeutic resistance; in-vitro models; personalized therapy
(This special issue belongs to the Section Tumor Microenvironment)
Pheochromocytoma and Paraganglioma: Molecular Insights and Clinical Frontiers
edited by
submission deadline 31 Jul 2026 | Viewed by 189 | Submission Open
Keywords: pheochromocytoma and paraganglioma; hereditary cancer syndromes; genetic mutations; genotype– phenotype correlations; functional imaging; molecular diagnostics; biomarkers; precision oncology; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
The Immune Landscape of Prostate Cancer: From Mechanisms to Therapy
edited by and Tongyu Tong
submission deadline 31 Jul 2026 | Viewed by 188 | Submission Open
Keywords: tumor immune microenvironment; immunotherapy; immune evasion; biomarkers; translational research
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Palliative and Precision Medicine Treatment for Biliary Tract Cancers (BTCs)
edited by
submission deadline 31 Jul 2026 | Viewed by 185 | Submission Open
Keywords: biliary tract cancers; precision medicine; palliative care; targeted therapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Radiomics and Artificial Intelligence in Tumor and Normal Organ Imaging
edited by
submission deadline 31 Jul 2026 | Viewed by 184 | Submission Open
Keywords: radiomics; artificial intelligence; tumor imaging; normal organ imaging; quantitative imaging biomarkers; precision oncology; treatment response assessment
(This special issue belongs to the Section Methods and Technologies Development)
Recent Advances and Emerging Directions in Lung Cancer Radiotherapy
edited by Arturo Navarro-Martín
submission deadline 31 Jul 2026 | Viewed by 177 | Submission Open
Keywords: lung cancer; hypofractionated radiotherapy; lattice; flash therapy; protons
(This special issue belongs to the Section Cancer Therapy)
T Cells in Cancer Immunology
edited by Dunfang Zhang
submission deadline 31 Jul 2026 | Viewed by 171 | Submission Open
Keywords: CD4+ T cell; CD8+ T cell; tumor immunotherapy; immune checkpoint therapy; CAR-T; adoptive T-cell therapy; tumor immune microenvironment
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Advances in Exosomes and Cancer Therapy
edited by and
submission deadline 31 Jul 2026 | Viewed by 167 | Submission Open
Keywords: exosomes; extracellular vesicles; isolation of exosomes; cancer therapy; tumor microenvironment; exosome engineering; drug delivery systems; cancer biomarkers; immunomodulation; precision oncology
(This special issue belongs to the Section Cancer Therapy)
State-of-the-Art Treatments in Neurosurgery for Central Nervous System Tumors
edited by
submission deadline 31 Jul 2026 | Viewed by 161 | Submission Open
Keywords: neurosurgery; central nervous system tumor; advanced imaging; molecular diagnostics; intraoperative technologies; precision therapeutics
(This special issue belongs to the Section Methods and Technologies Development)
Current Progress in the Clinical Management and Basic Science of Head and Neck Cancer: 2nd Edition
edited by
submission deadline 31 Jul 2026 | Viewed by 160 | Submission Open
Keywords: head and neck cancer; immunotherapy; chemoradiotherapy; surgery; molecular biology; oncogenesis; cancer immunology
Cutaneous T-Cell Lymphomas in Special Populations
edited by and Caroline Myers
submission deadline 31 Jul 2026 | Viewed by 160 | Submission Open
Keywords: cutaneous T-cell lymphoma; adult T-cell leukemia/lymphoma; lymphoproliferative disorder; hematopoietic stem cell transplant; secondary malignancy; pediatric lymphoma; skin of color; health care disparities; translational research
Medical Imaging and Artificial Intelligence in Cancer: 2nd Edition
edited by Debiao Li and
submission deadline 31 Jul 2026 | Viewed by 158 | Submission Open
Keywords: cancer; medical imaging; magnetic resonance imaging; computed tomography; artificial intelligence; image analysis; cancer detection; cancer prediction; cancer characterization
(This special issue belongs to the Section Methods and Technologies Development)
Mantle Cell Lymphoma: Onwards and Upwards
edited by Sunil Iyengar
submission deadline 31 Jul 2026 | Viewed by 155 | Submission Open
Keywords: mantle cell lymphoma; B-cell non-Hodgkin  lymphoma; targeted therapy; prognostic biomarkers; treatment resistance
(This special issue belongs to the Section Cancer Therapy)
The TGF-β Pathway in Hepatocellular Carcinoma
edited by Dan Feng
submission deadline 31 Jul 2026 | Viewed by 149 | Submission Open
Keywords: hepatocellular carcinoma; HCC; TGF-β
(This special issue belongs to the Section Cancer Pathophysiology)
Triggered Drug Delivery Strategies for Glioblastoma
edited by Maria Mendes and Mariana Magalhães
submission deadline 31 Jul 2026 | Viewed by 147 | Submission Open
Keywords: glioblastoma; stimuli-responsive drug delivery; tumor microenvironment; smart nanocarriers; endogenous-triggered release; external stimulus-activated therapy; combination therapy; translational nanomedicine
(This special issue belongs to the Section Cancer Drug Development)
Advances in Acute Lymphoblastic Leukemia Treatment
edited by
submission deadline 31 Jul 2026 | Viewed by 140 | Submission Open
Keywords: acute lymphoblastic leukemia; biology; clinical trial; treatment; chemotherapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Crosstalk Mechanisms in Liver Cancer Microenvironments
edited by
submission deadline 31 Jul 2026 | Viewed by 136 | Submission Open
Keywords: cancer-associated fibroblast (CAF); tumor-associated macrophage (TAM); tumor immune microenvironment (TIME); fibrosis; extracellular matrix; metabolism; miRNA; microbiota; spatial transcriptome; angiogenesis
(This special issue belongs to the Section Tumor Microenvironment)
Driving Progress in Urological Cancer Outcomes: Predictive Factors and Treatment Innovations
edited by Juan Gómez Rivas
submission deadline 31 Jul 2026 | Viewed by 123 | Submission Open
Keywords: urological cancers; prostate cancer; bladder cancer; kidney cancer; prognostic factors; treatment outcomes
Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer
edited by José Luís Sánchez-Iglesias and Ursula Acosta
submission deadline 31 Jul 2026 | Viewed by 98 | Submission Open
Keywords: ovarian cancer; HIPEC; cytoreductive surgery
Advances in Esophageal Cancer Treatment
edited by , , Pieter Van der Sluis and
submission deadline 1 Aug 2026 | 3 articles | Viewed by 13965 | Submission Open
Keywords: gastric cancer; esophageal cancer; esophagectomy; chemotherapy; radiotherapy; immunotherapy; perioperative management; artificial intelligence
(This special issue belongs to the Section Cancer Therapy)
Novel Therapies in Metastatic Castration-Resistant Prostate Cancer
edited by Kathryn E. Meier
submission deadline 1 Aug 2026 | 2 articles | Viewed by 5244 | Submission Open
Keywords: signal transduction inhibitors; targeted therapies; immunotherapy; radiopharmaceuticals; PARP inhibitors; biomarker-based approaches
(This special issue belongs to the Section Cancer Therapy)
Clinical Trials and Evolving Treatment Paradigms in Urologic Cancers
edited by
submission deadline 1 Aug 2026 | 4 articles | Viewed by 3440 | Submission Open
Keywords: urologic cancers; clinical trials; prostate cancer; bladder cancer; kidney cancer; testicular cancer; systemic therapy; meta-analysis; biomarkers; oncology innovation
(This special issue belongs to the Section Clinical Research of Cancer)
Gynecological Oncology and Robotic Surgery submission deadline 1 Aug 2026 | Viewed by 253 | Submission Open
Keywords: gynecologic oncology; robotic-assisted surgery; minimally invasive surgery; artificial intelligence; surgical innovation; multidisciplinary care
(This special issue belongs to the Section Methods and Technologies Development)
Pathological and Spatial Insights into Pancreatic Cancer Biology
edited by and Tianye Li
submission deadline 1 Aug 2026 | Viewed by 180 | Submission Open
Keywords: spatial pathology; digital pathology; multiplexed imaging; spatial transcriptomics; computational pathology; AI-assisted image analysis; machine learning in pathology; spatial biomarker discovery; pancreatic cancer
(This special issue belongs to the Section Molecular Cancer Biology)
Nanotechnology in Radiation Oncology
edited by
submission deadline 3 Aug 2026 | Viewed by 154 | Submission Open
Keywords: external radiation therapy; brachytherapy; hyperthermia; cancer; nanotechnology; radiosensitizers; nanoparticles
Pediatric Cancer Research from Basic Biology to Experimental Therapy
edited by
submission deadline 7 Aug 2026 | 5 articles | Viewed by 17788 | Submission Open
Keywords: pediatric tumors; solid cancers; leukemias; cancer predisposition syndromes; genetics; omics; immunotherapy; therapy resistance
(This special issue belongs to the Section Pediatric Oncology)
Preclinical and Clinical Research on the Efficacy of Anticancer Drugs
edited by Andrzej Hellmann, Joanna Jakobkiewicz-Banecka and Jan Lica
submission deadline 7 Aug 2026 | 4 articles | Viewed by 11678 | Submission Open
Keywords: clinical trials; preclinical research; anticancer drugs; drug efficacy; drug development; cancer therapy; therapeutic strategies; safety assessment; pharmacodynamics; pharmacokinetics
(This special issue belongs to the Section Clinical Research of Cancer)
The Clinical Trials and Management of Acute Myeloid Leukemia: 2nd Edition
edited by
submission deadline 7 Aug 2026 | 2 articles | Viewed by 3963 | Submission Open
Keywords: acute myeloid leukemia; clinical trials; translational research; targeted therapies; novel agents
(This special issue belongs to the Section Clinical Research of Cancer)
Innovations in Active Surveillance Management of Early Prostate Cancer submission deadline 8 Aug 2026 | 2 articles | Viewed by 2645 | Submission Open
Keywords: prostate cancer; risk stratification; active surveillance; predictive markers; personalized management; imaging; biomarkers; clinical pathways; patient outcomes; standardizing care; attrition; cohort studies
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Targeted Therapies in Sarcomas: Overcoming Resistance and Improving Outcomes
edited by and Mohammed M. Milhem
submission deadline 8 Aug 2026 | Viewed by 268 | Submission Open
Keywords: sarcoma; targeted therapy; resistance mechanisms; combination therapy; biomarkers; precision oncology; translational research; clinical trials
(This special issue belongs to the Section Tumor Microenvironment)
Clinical Surgery for Hepato-Pancreato-Biliary (HPB) Cancer submission deadline 10 Aug 2026 | 10 articles | Viewed by 21309 | Submission Open
Keywords: pancreatic malignancies; HPB malignancies; pancreatic ductal adenocarcinoma; liver cholangiocarcinoma; HPB surgery; liver resection; pancreatic resection
(This special issue belongs to the Section Cancer Therapy)
Near-Infrared Photoimmunotherapy for Cancer Treatment: 2nd Edition
edited by
submission deadline 10 Aug 2026 | 1 articles | Viewed by 1528 | Submission Open
Keywords: NIR-PIT; phototherapy; monoclonal antibody; imaging biomarker; immunotherapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Mesothelioma Environmental Risk Factors and Epidemiological and Biological Insights
edited by Sonja Klebe
submission deadline 10 Aug 2026 | 1 articles | Viewed by 687 | Submission Open
Keywords: mesothelioma; asbestos; mesothelial proliferation; therapy; marker
Bridging Translational and Clinical Oncology in Gastrointestinal Cancers: Molecular Mechanisms to Therapeutic Advances submission deadline 10 Aug 2026 | Viewed by 368 | Submission Open
Keywords: gastrointestinal cancers; translational oncology; molecular mechanisms; biomarkers; immunotherapy; radiomics; precision medicine; therapeutic advances
(This special issue belongs to the Section Methods and Technologies Development)
The Tumorigenesis Mechanism of Breast Cancer
edited by Swayam Prabha
submission deadline 10 Aug 2026 | Viewed by 325 | Submission Open
Keywords: breast cancer; tumor microenvironment; myeloid-derived suppressor cells; immune evasion; premetastatic niche; epithelial– mesenchymal transition; PI3K/AKT/mTOR; MAPK/ERK; Wnt/β -catenin; BRCA1/2; TP53; estrogen signaling; targeted therapy; nanomedicine; biologics; precision oncology; translational research
(This special issue belongs to the Section Molecular Cancer Biology)
Research on Clinical Treatment of Mesothelioma: 2nd Edition
edited by
submission deadline 10 Aug 2026 | Viewed by 216 | Submission Open
Keywords: pleural mesothelioma; targeted therapy; local treatments; radiomics; genetic traits; occupational health; asbestos exposure
(This special issue belongs to the Section Clinical Research of Cancer)
Inflammatory Bowel Disease and Cancers: What Connections Lie Between Them?
edited by
submission deadline 10 Aug 2026 | Viewed by 102 | Submission Open
Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; cancers
Innovative Immunotherapies: CAR-T Cell Therapy for Cancers: 2nd Edition
edited by
submission deadline 14 Aug 2026 | 3 articles | Viewed by 13617 | Submission Open
Keywords: CAR-T; NK-CAR; immunotherapy; cancer; resistance mechanisms
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Cytoreduction in Gynecologic Oncology
edited by Sabrina Piedimonte
submission deadline 14 Aug 2026 | Viewed by 125 | Submission Open
Keywords: cytoreduction; ovarian cancer; endometrial cancer; minimally invasive surgery; AI
(This special issue belongs to the Section Cancer Therapy)
Recent Updates and Future Perspectives on Anti-Cancer Agents submission deadline 15 Aug 2026 | 3 articles | Viewed by 6468 | Submission Open
Keywords: cancer; anti-cancer agents; targeted therapy; drug resistance; therapeutic agents; natural compounds; combination therapy; nanotherapy; translational therapy; immunotherapy
(This special issue belongs to the Section Cancer Drug Development)
Minimally Invasive Therapies in Urologic Cancers
edited by Eric M. Walser and
submission deadline 15 Aug 2026 | 4 articles | Viewed by 4955 | Submission Open
Keywords: laparoscopic surgery; robotic-assisted surgery; ablation; high-intensity focused ultrasound; partial nephrectomy; minimally invasive procedures; urologic cancers
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Precision Medicine: Targeting Known and Emerging Oncogenic Targets in Lung Cancer (2nd Edition)
edited by
submission deadline 15 Aug 2026 | 3 articles | Viewed by 4732 | Submission Open
Keywords: precision oncology; lung cancer; oncogenic target; targeted therapy; biomarker; diagnosis
(This special issue belongs to the Section Molecular Cancer Biology)
The Elderly Multiple Myeloma Patient in the Era of Quad Therapy and CAR-T Cells
edited by James J. Ignatz-Hoover and Koen Van Besien
submission deadline 15 Aug 2026 | 1 articles | Viewed by 3023 | Submission Open
Keywords: multiple myeloma; quad therapy; CAR-T; elderly
(This special issue belongs to the Section Cancer Therapy)
Clinical Applications of Advanced MRI Technologies for Cancers
edited by
submission deadline 15 Aug 2026 | 2 articles | Viewed by 1876 | Submission Open
Keywords: advanced MRI techniques; multiparametric imaging; quantitative biomarkers; artificial intelligence; treatment response assessment; precision oncology; radiomics; cancer diagnosis; functional imaging; molecular imaging
(This special issue belongs to the Section Methods and Technologies Development)
Rare Genitourinary Cancers submission deadline 15 Aug 2026 | 1 articles | Viewed by 960 | Submission Open
Keywords: rare genitourinary tumors; penile cancer; testicular cancer; urethral cancer; adrenal cancer; variant histology; upper tract urothelial carcinoma; extramammary Paget’ s disease; urologic oncology; rare cancers
(This special issue belongs to the Section Clinical Research of Cancer)
Advances in Immunotherapy for Acute Myeloid Leukemia
edited by
submission deadline 15 Aug 2026 | 1 articles | Viewed by 795 | Submission Open
Keywords: acute myeloid leukemia; immunotherapy; immune response; T-cell; cellular therapies; immune checkpoint inhibitors; treatment
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Prostate-Specific Membrane Antigen (PSMA)-Targeted Radionuclide Therapy in Cancer
edited by and
submission deadline 15 Aug 2026 | Viewed by 377 | Submission Open
Keywords: PSMA-TRNT; radioligand therapy; radionuclide therapy; theranostics; prostate-specific membrane antigen (PSMA); PSMA targeted; PSMA ligands; prostate cancer (PCa); metastatic castration-resistant prostate cancer (mCRPC)
(This special issue belongs to the Section Methods and Technologies Development)
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