Cellular and Molecular Mechanisms in Reproductive System Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Reproductive Cells and Development".
Deadline for manuscript submissions: 31 October 2024 | Viewed by 121
Special Issue Editors
Interests: cancer biology; cancer diagnosis; cancer genetics; cancer immunology; cancer stem cell; cancer therapy; cellular immunology; gynaecological cancers; gynaecological diseases; stem cell biology
Interests: male reproductive system; fertility; microfluidics; stem cells; nanofluidics; organ-on-a-chip; diagnostics and therapeutics
Special Issues, Collections and Topics in MDPI journals
Interests: stem cells; tissue specific stem cells; pluripotent stem cells; cellular reprogramming; developmental biology; tissue differentiation; tissue engineering; disease modelling; stem cell drugs; screening of therapeutic agents
Special Issue Information
Dear Colleagues,
Reproductive system diseases encompass a wide range of diseases from benign to malignant, which disrupt the usual functioning of the male and female reproductive systems. It can significantly affect fertility, pregnancy outcomes, and overall reproductive health. Thus, exploring cellular and molecular mechanisms underlying these diseases will help to develop effective diagnostic tools, treatments, and preventive strategies.
This Special Issue aims to explore the latest advancements in research related to the cellular and molecular mechanisms involved in reproductive system diseases by inviting original research articles and review articles in this area. Topics of interest related to the reproductive system are listed below. However, relevant topics outside of these keywords are also welcome.
- Male reproductive system;
- Female reproductive system;
- Stem cell;
- Cell signalling;
- Pathogenesis;
- Genetic factors;
- Cellular mechanisms;
- Molecular mechanisms;
- Hormonal regulation;
- Reproductive immunology;
- Adverse pregnancy outcomes;
- Biomarkers;
- Therapeutic targets;
- Infertility;
- Cancers;
- Sexually transmitted infections (STIs).
Overall, this Special Issue will serve as a platform to exchange ideas, insights, discoveries, and perspectives on these diseases’ pathologies.
Dr. Arnab Ghosh
Prof. Dr. Majid E Warkiani
Dr. Sujoy K. Dhara
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- male reproductive system
- female reproductive system
- hormonal regulation
- reproductive immunology
- adverse pregnancy outcomes
- infertility
- sexually transmitted infections (STIs)
Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Effect of paternal body mass index on cumulative live birth rates: analysis of 3,311 embryo transfers of couples with autologous oocytes
Authors: Nicolás Garrido; Laura Mossetti
Affiliation: Director, Research Administration, Research/Innovation IVI Foundation Director Edificio Biopolo – Instituto de Investigación Sanitaria la Fe Avenida Fernando Abril Martorell, 106 - Torre A, Planta 1ª 46026 Valencia
Abstract: Objective: To investigate the effect of paternal body mass index (BMI) on clinical outcomes by assessing the cumulative live birth rates (CLBRs) per number of embryo transfers (ETs), embryos replaced (EmbR), and oocytes used (OU) in consecutive treatments to achieve the first newborn.
Design: A retrospective observational multicentric study was conducted, and Kaplan-Meier survival curves were generated to calculate the CLBR with regard to the paternal BMI adjusted by relevant confounders through Cox regression models.
Subjects: Data from couples undergoing in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) treatment in Spanish IVIRMA fertility clinics between January 2018 and December 2023 using their own sperm sample and own oocytes.
Male BMI was categorized in: normal weight (18.5-24.99 kg/m2) (N), overweight (25-29.99 kg/m2) (OV) and obese (≥ 30 kg/m2) (OB) patients.
Intervention(s): None.
Main outcomes measured: Sperm quality parameters and reproductive outcomes (biochemical, clinical, evolutive pregnancy) per embryo transfer and CLBR per ET, per EmbR and OU.
