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Diagnostics
Special Issues
Advances in Diagnosis and Management of Sinonasal Disorders
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Advances in Diagnosis and Management of Sinonasal Disorders

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 2277

Special Issue Editors

Dr. Ta-Jen Lee

E-Mail Website
Guest Editor
Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan
Interests: endoscopic sinus surgery; sinonasal neoplasms; septoplasty; turbinoplasty; allergic rhinitis; empty nose syndrome; rhinoplasty
Special Issues, Collections and Topics in MDPI journals
Dr. Po-Hung Chang

E-Mail Website
Guest Editor
Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan
Interests: endoscopic sinus surgery; sinonasal neoplasms; chronic rhinosinusitis; skull base surgery
Dr. Chien-Chia Huang

E-Mail Website
Guest Editor
Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan
Interests: rhinology; chronic rhinosinusitis; empty nose syndrome; obstructive sleep apnea; paediatric otorhinolaryngology

Special Issue Information

Dear Colleagues,

Sinonasal Disorders, such as acute/chronic rhinosinusitis, nasal polyposis, allergic/non-allergic rhinitis, empty nose syndrome, sinonasal neoplasms, etc., frequently cause physical and psychiatric illness. Despite the rapid progress of medicine, some sinonasal disorders remain complex and have a significant impact on the global economy in the modern era. Early detection and proper management of sinonasal disorders deserve further attention. Advances in timely diagnosis and proper management would provide practical information about precise prognosis and likely response to medical or surgical therapy and are therefore pivotal.

On account of the great advances in the molecular and pathophysiological understanding of complex sinonasal disorders, the relevance of advances for diagnosis and management has attracted a great deal of attention. This Special Issue will address current advances in the diagnosis and management of sinonasal disorders.

We welcome you to submit original research articles or comprehensive reviews to this Special Issue.

Dr. Ta-Jen Lee
Dr. Po-Hung Chang
Dr. Chien-Chia Huang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sinonasal disorder
  • chronic rhinosinusitis
  • rhinitis
  • empty nose syndrome
  • nasal septal deviation
  • obstructive sleep apnea
  • sinonasal tumor
  • skull base surgery
  • paediatric otorhinolaryngology

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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Research

14 pages, 1210 KiB  
Article
Objective and Subjective Outcomes Following Radiofrequency of Inferior Turbinates in Patients with Sleep-Disordered Breathing
by Alfonso Luca Pendolino, Samit Unadkat, Ryan Chin Taw Cheong, Ankit Patel, Joshua Ferreira, Bruno Scarpa and Peter J. Andrews
Diagnostics 2024, 14(16), 1820; https://doi.org/10.3390/diagnostics14161820 - 21 Aug 2024
Viewed by 523
Abstract
Background: Nasal obstruction is a frequent problem amongst patients with sleep-disordered breathing (SDB). Radiofrequency of the inferior turbinates (RFIT) is commonly utilized for inferior turbinate (IT) reduction but its effectiveness in SDB patients remains unproven. We aim to evaluate long-term objective and subjective [...] Read more.
Background: Nasal obstruction is a frequent problem amongst patients with sleep-disordered breathing (SDB). Radiofrequency of the inferior turbinates (RFIT) is commonly utilized for inferior turbinate (IT) reduction but its effectiveness in SDB patients remains unproven. We aim to evaluate long-term objective and subjective nasal, olfactory and sleep outcomes following RFIT in SDB patients. Methods: Patients were assessed at baseline (T0) and at 3 months (T1), 6 months (T2) and 12 months (T3) following RFIT. At T0, T1, T2 and T3, the patients underwent objective assessments of their nasal airways and smell function and an evaluation of their quality-of-life, sinonasal, olfactory and sleep symptoms. Sleep studies were carried out at T0 and T2. Results: Seventeen patients (with a median age of 42 years) underwent RFIT. A statistically significant objective and subjective improvement of the patients’ nasal airways was demonstrated at T1. No other statistically significant changes were observed in the patients’ nasal airways, smell, sleep study parameters or patient-reported outcomes at the other follow-ups. A multivariate analysis confirmed a statistically significant influence of age (older), sex (male), a higher BMI, the presence of septal deviation and the presence of allergic rhinitis in some of the studies’ parameters. A statistically significant objective and subjective improvement of the patients’ nasal airways was confirmed in the fitted model when considering the influence of the available variables. Conclusions: Our study confirms that the benefits of RFIT alone in SDB patients are limited and possibly only in the short-term period. Patient-related variables can potentially influence the final outcomes. Full article
(This article belongs to the Special Issue Advances in Diagnosis and Management of Sinonasal Disorders)
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11 pages, 937 KiB  
Article
Risk Factors for Isolated Sphenoid Sinusitis after Endoscopic Endonasal Transsphenoidal Pituitary Surgery
by Yun-Chen Chang, Yu-Ning Tsao, Chi-Cheng Chuang, Cheng-Yu Li, Ta-Jen Lee, Chia-Hsiang Fu, Kuo-Chen Wei and Chi-Che Huang
Diagnostics 2024, 14(7), 758; https://doi.org/10.3390/diagnostics14070758 - 2 Apr 2024
Cited by 1 | Viewed by 1366
Abstract
(1) Background: Transsphenoidal pituitary surgery can be conducted via microscopic or endoscopic approaches, and there has been a growing preference for the latter in recent years. However, the occurrence of rare complications such as postoperative sinusitis remains inadequately documented in the existing literature. [...] Read more.
(1) Background: Transsphenoidal pituitary surgery can be conducted via microscopic or endoscopic approaches, and there has been a growing preference for the latter in recent years. However, the occurrence of rare complications such as postoperative sinusitis remains inadequately documented in the existing literature. (2) Methods: To address this gap, we conducted a comprehensive retrospective analysis of medical records spanning from 2018 to 2023, focusing on patients who underwent transsphenoidal surgery for pituitary neuroendocrine tumors (formerly called pituitary adenoma). Our study encompassed detailed evaluations of pituitary function and MRI imaging pre- and postsurgery, supplemented by transnasal endoscopic follow-up assessments at the otolaryngology outpatient department. Risk factors for sinusitis were compared using univariate and multivariate logistic regression analyses. (3) Results: Out of the 203 patients included in our analysis, a subset of 17 individuals developed isolated sphenoid sinusitis within three months postoperation. Further scrutiny of the data revealed significant associations between certain factors and the occurrence of postoperative sphenoid sinusitis. Specifically, the classification of the primary tumor emerged as a notable risk factor, with patients exhibiting nonfunctioning pituitary neuroendocrine tumors with 3.71 times the odds of developing sinusitis compared to other tumor types. Additionally, postoperative cortisol levels demonstrated a significant inverse relationship, with lower cortisol levels correlating with an increased risk of sphenoid sinusitis postsurgery. (4) Conclusions: In conclusion, our findings underscore the importance of considering tumor classification and postoperative cortisol levels as potential predictors of postoperative sinusitis in patients undergoing transsphenoidal endoscopic pituitary surgery. These insights offer valuable guidance for clinicians in identifying at-risk individuals and implementing tailored preventive and management strategies to mitigate the occurrence and impact of sinusitis complications in this patient population. Full article
(This article belongs to the Special Issue Advances in Diagnosis and Management of Sinonasal Disorders)
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