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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms and Immunotherapy of Soft Tissue and Bone Sarcomas
edited by and
submission deadline 20 May 2024 | 1 articles | Viewed by 3017 | Submission Open
(This special issue belongs to the Section Molecular Oncology)
The Multiple Mechanisms Underlying Neuropathic Pain (III) submission deadline 20 May 2024 | 2 articles | Viewed by 2984 | Submission Open
Keywords: neuropathic pain; nociception; neuroinflammation; sex differences; sex hormones; analgesic response
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Research on Cardiac Troponin
edited by
submission deadline 20 May 2024 | 3 articles | Viewed by 2860 | Submission Open
Keywords: cardiac troponins; troponin T and troponin I; myocardial damage; cardiac troponin metabolism; molecular mechanisms; molecular biology; mechanisms of release; transportation of cardiac troponins; mechanisms of elimination; expression of cardiac troponins; regulation of myocardial contraction; post-translational modifications; folding; phosphorylation; glycosylation; proteolysis; myocarditis; Takotsubo syndrome; heart failure; cardiac amyloidosis; acute myocardial infarction; cardiomyopathies; cardiac arrhythmias; pulmonary embolism; diagnostics; non-invasive diagnostics; chronic renal failure  
(This special issue belongs to the Section Molecular Biology)
Advances in Metal Metabolism Research 2.0
edited by
submission deadline 20 May 2024 | 2 articles | Viewed by 2810 | Submission Open
Keywords: molecular evolution; phylogeny; epigenetics; adaptation; gene networks; metal metabolism; metal toxicity; metal homeostasis; metallo-enzymes and metallo-proteins; evolutionary engineering
(This special issue belongs to the Section Biochemistry)
Mitochondrial Dysfunction: A Metabolic, Cardiovascular, Neurodegenerative and Neuromuscular Issue 2.0
edited by , and Claudia Nesti
submission deadline 20 May 2024 | 2 articles | Viewed by 2625 | Submission Open
Keywords: bioenergetics; mitochondrial disorders; biomarkers; OxPhos complexes; mitochondrial DNA; aging; neurodegenerative diseases; cardiovascular diseases; metabolic diseases; therapies to counteract mitochondrial dysfunction
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Genetics and Epigenetics of Cardiometabolic Diseases
edited by
submission deadline 20 May 2024 | 2 articles | Viewed by 2109 | Submission Open
Keywords: obesity; insulin resistance; diabetes mellitus; cardiovascular diseases; metabolic syndrome; non-alcoholic fatty liver disease; dyslipidaemia; coronary artery disease; chronic kidney disease; hypertension
(This special issue belongs to the Section Molecular Genetics and Genomics)
Conducting and Biodegradable Polymers, a New Concept for Current and Future Biomedical Applications 2.0
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1941 | Submission Open
Keywords: biomimetic; biodegradable polymers; conducting polymers; conducting composites and hybrids; synthesis of conducting/biodegradable polymers; structure properties of conducting polymers; polymer synthesis; temperature induced phase separation; biomedical/biological applications; scaffolds; tissue regeneration; biosensing
(This special issue belongs to the Section Macromolecules)
Functional Genomes in Plant Diseases and Pests Management
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1902 | Submission Open
Keywords: induced systemic resistance; genetics of plant-microbe interactions; endophytes; phytopathology; functional genomes
(This special issue belongs to the Section Molecular Plant Sciences)
Beyond Compatibility: Unraveling the Molecular Dynamics of Biomaterial-Host Interactions
edited by Samuel J Lin
submission deadline 20 May 2024 | 2 articles | Viewed by 1863 | Submission Open
Keywords: molecular dynamics; biomaterial‒host interactions; biofilms; bacteria‒host interaction; chronic inflammation; rejection
(This special issue belongs to the Section Materials Science)
Calpain Family in Health and Diseases: The Road Ahead
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1855 | Submission Open
Keywords: chronic inflammation; gene-targeted mice; limited proteolytic cleavage; protein catabolism; cardiometabolic disease; cancer; neurodegenerative disease  
(This special issue belongs to the Section Macromolecules)
Molecular Mechanisms and Therapies of Glioblastoma
edited by , Cristina Pagano and
submission deadline 20 May 2024 | 2 articles | Viewed by 1811 | Submission Open
Keywords: GBM; epigenetics; temozolomide; MGMT
(This special issue belongs to the Section Molecular Oncology)
Molecular Research on Neuronal Cell Death and Neurogenesis submission deadline 20 May 2024 | 1 articles | Viewed by 1757 | Submission Open
(This special issue belongs to the Section Molecular Neurobiology)
Biopolymers in Nano and Micro Scales for Food Biotechnology Application
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1756 | Submission Open
Keywords: polymers; biopolymers; food; micro-scale; nanoscale; composites; biosynthesis; antimicrobial; antifungal; food texture
(This special issue belongs to the Section Macromolecules)
Biological Liquid-Liquid Phase Separation, Biomolecular Condensates, and Membraneless Organelles 2.0 submission deadline 20 May 2024 | 1 articles | Viewed by 1633 | Submission Open
(This special issue belongs to the Section Molecular Biophysics)
Molecular Mechanisms of Neuropsychiatric Diseases
edited by Dmitrii A. Pavlov
submission deadline 20 May 2024 | 1 articles | Viewed by 1529 | Submission Open
Keywords: neurotransmitters; synaptic plasticity; epigenetics; genetic mutations; inflammation; oxidative stress; mitochondrial dysfunction; apoptosis; neuroinflammation; excitotoxicity; glutamate
(This special issue belongs to the Section Molecular Neurobiology)
Immunotherapy in Tumors: Treatments, Complications and Diagnostic Evaluation of Response
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1413 | Submission Open
Keywords: cancer immunotherapy; immune checkpoint inhibitor; complications; potential side-effects; immune response
(This special issue belongs to the Section Molecular Oncology)
Advances in Plant Physiology, Biochemistry, and Biotechnology for Natural Product Synthesis
edited by
submission deadline 20 May 2024 | 2 articles | Viewed by 1370 | Submission Open
Keywords: medicinal plants; natural products; phytomedicine
(This special issue belongs to the Section Molecular Plant Sciences)
Pathophysiology and Novel Therapeutic Strategies of Neurological Diseases
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1367 | Submission Open
Keywords: neurological disorders; neurogenetic diseases; pathophysiological mechanisms; mitochondrial diseases; spinal muscular atrophy; neurodegenerative diseases; treatment; therapeutics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Ubiquitin Receptors and Associated Mechanisms Involved in Targeting Proteins Modified with Diverged Ubiquitin Signals to Distinct Cellular Processes
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1320 | Submission Open
Keywords: ubiquitin; ubiquitin signals; ubiquitin binding; ubiquitin receptor; 26S proteasome; endocytosis; autophagy; epigenetic regulation; DNA repair
(This special issue belongs to the Section Molecular Plant Sciences)
Cell Death in Biology and Diseases 3.0 submission deadline 20 May 2024 | 1 articles | Viewed by 1293 | Submission Open
Keywords: programmed cell death; apoptosis; necrosis; autoimmune diseases; cancer research; pharmacognosy; photodynamic therapy; immune system
(This special issue belongs to the Section Molecular Biology)
Role of MicroRNAs in Cancer Development and Treatment 2.0
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1274 | Submission Open
Keywords: microRNAs (miRNAs); transcriptomics; functional studies; cancer pathobiology; solid tumors; hematological malignancies; molecular biomarkers; therapeutic targets; apoptosis; anticancer drugs radiotherapy; chemotharapy failure
(This special issue belongs to the Section Molecular Oncology)
Multiplicity of Cerebrospinal Fluid Functions in Health and Disease
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1268 | Submission Open
Keywords: cerebrospinal fluid; choroid plexus; glymphatics; arachnoid; physiology; function; disease
(This special issue belongs to the Section Molecular Neurobiology)
The Role of Vitamin C in Human Health and Diseases submission deadline 20 May 2024 | 1 articles | Viewed by 1242 | Submission Open
Keywords: vitamin C; vitamin C deficiency; vitamin C supplementation; recommended dose; immune system; health; disease; inflammation; cell metabolism; oxidative stress; pharmacokinetics; immunity
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Proteomics and Nanotechnology for Medical and Pharmacological Applications
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1227 | Submission Open
Keywords: biomolecules; peptides; proteomics; transcriptomics; nanotechnology; venomics
(This special issue belongs to the Section Molecular Pharmacology)
Natural Products and Neuroprotection 4.0 submission deadline 20 May 2024 | 1 articles | Viewed by 1185 | Submission Open
Keywords: oxidative stress; inflammation; protein misfolding; natural compounds; nutraceuticals; phytochemicals neurodegeneration; Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis; multiple sclerosis; Huntington’ s disease
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Properties, Biosynthesis and Application of Antimicrobial Compounds submission deadline 20 May 2024 | 1 articles | Viewed by 1146 | Submission Open
Keywords: antimicrobial compounds of microorganisms; whole genome sequencing; secondary metabolites; antimicrobial activity; biosynthesis; application
(This special issue belongs to the Section Molecular Microbiology)
Regulation of Ubiquitin Family Signaling in Disease 2.0
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1103 | Submission Open
Keywords: ubiquitin; SUMO; NEDD8; ISG15; FAT10; ubiquitin-like proteins; autophagy; proteasome
(This special issue belongs to the Section Molecular Biology)
Advances in Biofuels and Green Catalysts submission deadline 20 May 2024 | 1 articles | Viewed by 1093 | Submission Open
Keywords: biofuels; green catalysts; enzymatic catalysis; renewable energy; catalytic mecanism; green chemistry; integrated biorefinery
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Recent Progress in Addition Reactions and Organic Synthesis
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 937 | Submission Open
Keywords: addition reactions; organic synthesis; synthesis mechanism
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Application and Latest Progress of Bioinformatics in Drug Discovery
edited by Alfonso Trezza
submission deadline 20 May 2024 | 1 articles | Viewed by 800 | Submission Open
Keywords: molecular dynamics and docking simulation; molecular modeling; target and drug discovery; artificial intelligence; big data
(This special issue belongs to the Section Molecular Informatics)
Drug Delivery Systems: Current Status in the Treatment of Human Diseases submission deadline 20 May 2024 | 1 articles | Viewed by 703 | Submission Open
Keywords: human diseases; cancer; cardiovascular disease; biomaterials; drug delivery; targeted therapies; theranostics
(This special issue belongs to the Section Molecular Pharmacology)
Male Genitourinary Tumors: Molecular and Cellular Mechanism
edited by
submission deadline 20 May 2024 | Viewed by 461 | Submission Open
Keywords: penile carcinoma; tumor biology; immune modulator; HPV   TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Advances in Cystic Fibrosis: Pathophysiology, Molecular Mechanisms and Novel Therapies
edited by Virginia De Rose
submission deadline 20 May 2024 | Viewed by 358 | Submission Open
Keywords: cystic fibrosis; pathophysiology; molecular pathways and mechanisms; novel therapies; CFTR modulators
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Advances in Anti-microbial Biomaterials submission deadline 20 May 2024 | Viewed by 333 | Submission Open
Keywords: SARS-CoV-2; microbial infections; biomaterials; antibacterial; antiviral; antifungal; microbial resisistance
(This special issue belongs to the Section Materials Science)
Molecular Advances and Perspectives in Multiple Sclerosis
edited by Joao Jose Cerqueira and
submission deadline 20 May 2024 | Viewed by 328 | Submission Open
Keywords: astrocytes; axonal transection; demyelination; EBV; immunometabolism; insulin signaling; iron; lymphotoxin; microglia; mitochondria; neurodegeneration; oligodendrocytes; remyelination; brain barriers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cardiac Calcium Channels in Cardiovascular Function and Disease submission deadline 20 May 2024 | Viewed by 327 | Submission Open
(This special issue belongs to the Section Biochemistry)
Nuclear Receptors in Health and Diseases 2.0
edited by
submission deadline 20 May 2024 | Viewed by 249 | Submission Open
Keywords: nuclear receptors; hormone receptors; orphan receptors; retinoid receptors; PPARs; PXR; CAR; LXRs; FXR; RORs; RXRs; ERs; HNF4s; health; cancers; metabolic diseases; drug metabolism; agonists and antagonists; coactivators and corepressors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Molecular Research Targeting the Application of FFPE Tissue: Development and Updates
edited by William Mathieson
submission deadline 20 May 2024 | Viewed by 229 | Submission Open
Keywords: FFPE tissue; genomic medicine; diagnosis; immunohistochemistry
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms and Therapeutic Potential of Ion Channels in Human Diseases submission deadline 20 May 2024 | Viewed by 211 | Submission Open
Keywords: ion channels; cancer; channelopathies; electrophysiology; patch clamp
(This special issue belongs to the Section Molecular Biology)
Cancer Suicide Gene Therapy
edited by
submission deadline 20 May 2024 | Viewed by 210 | Submission Open
Keywords: directed enzyme prodrug therapy (DEPT); suicide gene therapy (SGT); gene-/virus-directed enzyme prodrug therapy (G-/V-DEPT); nitroreductase (NTR); hypoxia; transgene tracking
(This special issue belongs to the Section Molecular Oncology)
Cell Biology and Biochemistry Regulation Mediated by Natural Compounds
edited by
submission deadline 20 May 2024 | Viewed by 206 | Submission Open
Keywords: cellular targets; natural compounds; nutraceuticals; health-promoting effects; enzymatic activity; cell-based assays; in vivo; nanoencapsulation; delivery of natural compounds
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Cancer: Molecular Research and Novel Inflammatory Targets submission deadline 20 May 2024 | Viewed by 137 | Submission Open
Keywords: cancer; tumor microenvironment; molecular biology; biomarkers; novel and alternative therapies; inflammation; pharmacological inhibitors
(This special issue belongs to the Section Molecular Oncology)
The Role of Phosphatases in Human Disease
edited by
submission deadline 20 May 2024 | Viewed by 129 | Submission Open
Keywords: protein dephosphorylation; protein phosphatase; reversible phosphorylation; phospho-substrate; human diseases; cell signaling
(This special issue belongs to the Section Molecular Biology)
Epigenetic Controls for Gene Panels in Oncology submission deadline 20 May 2024 | Viewed by 124 | Submission Open
(This special issue belongs to the Section Molecular Genetics and Genomics)
The Role of Cytokines in Diseases submission deadline 22 May 2024 | 2 articles | Viewed by 1948 | Submission Open
Keywords: cytokines; inflammation; immune response; genetics; epigenetics; disease; infection; pathogen-associated molecular patterns; damage-associated molecular patterns; pattern-recognizing receptors; treatment
(This special issue belongs to the Section Biochemistry)
New Insights into Proteomics in Disease
edited by
submission deadline 24 May 2024 | 5 articles | Viewed by 6613 | Submission Open
Keywords: proteomics; disease biomarkers; data integration; bioinformatics; mass spectrometry; biochemical pathway; personalized medicine
(This special issue belongs to the Section Molecular Informatics)
Epilepsy: Molecular Mechanisms and Therapies submission deadline 24 May 2024 | 2 articles | Viewed by 4383 | Submission Open
Keywords: epilepsy; seizures; epileptogenesis; anticonvulsant drugs; ion channels; neurotransmitters; molecular mechanisms; epilepsy/seizure models
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Studies of Hematological Malignancies: Emphasis on Development of Flow-Cytometry and Cell-Sorting-Based Technics for Improving Diagnosis
edited by and Netanel A Horowitz
submission deadline 24 May 2024 | 1 articles | Viewed by 1220 | Submission Open
Keywords: laboratory hematology; hematological malignancies; flow cytometry and cell sorting; soluble biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Non-coding RNAs' Functionality-Diagnosis and Therapy in Cancer and Other Indications submission deadline 25 May 2024 | 16 articles | Viewed by 26866 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Circulating Cell-Free Nucleic Acids and Cancers 2.0
edited by
submission deadline 25 May 2024 | 6 articles | Viewed by 10081 | Submission Open
Keywords: biological fluids; cancer; cancer biomarkers; cfDI; cfDNA; cfNA; Copy number variation; ctDNA; ddPCR; disease-free survival; epigenetic; epigenetic sequencing; exosome; extracellular vesicle; genotyping; liquid biopsy; miRNA; mRNA; mutation; ncRNA; next-generation sequencing; overall survival; progression-free survival; recurrence-free survival; whole-exome sequencing
(This special issue belongs to the Section Molecular Oncology)
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