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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Insights into Platelet Biology and Function submission deadline 20 Sep 2024 | 1 articles | Viewed by 1572 | Submission Open
Keywords: platelets; thrombosis; hemostasis; reactivity
(This special issue belongs to the Section Molecular Biology)
Molecular Study of Renal Diseases submission deadline 20 Sep 2024 | 1 articles | Viewed by 1539 | Submission Open
Keywords: digital pathology; computational pathology; spatial biology; renal biopsy; chronic kidney disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms and Pharmacological Approaches for Brain Injury
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 1533 | Submission Open
Keywords: molecular mechanisms; therapeutical effects; brain injury; stroke; inflammation; autophagy; drug discover; target validation
(This special issue belongs to the Section Molecular Pharmacology)
Targeting Corneal Wound Healing: Molecular Access to Diagnosis, Pathophysiology, and Treatment
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 1491 | Submission Open
Keywords: corneal wound healing; optical visual performance; cornea; extracellular matrix; enzymatic activities; growth factors; cytokines
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Basis and Progress of Immunotherapy for Melanoma
edited by
submission deadline 20 Sep 2024 | 2 articles | Viewed by 1361 | Submission Open
Keywords: melanoma; immune checkpoint inhibitors; immune therapies; T cell; NK cells
(This special issue belongs to the Section Molecular Immunology)
Metal Toxicity in Animals: Recent Insights on Physiological and Molecular Aspects
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 1241 | Submission Open
Keywords: heavy metals; lanthanides; physiological and molecular pathways of cellular toxicology; environmental pollution; risk assessments; risk of mixing contaminants
(This special issue belongs to the Section Molecular Toxicology)
Liver Cancer 3.0
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 1221 | Submission Open
Keywords: liver cancer and mutations/genetics; liver cancer and gene regulation; liver cancer and stem cells; liver cancer and obesity; liver cancer and stress; liver cancer and clinical trials/therapies; liver cancer and epigenetic gene regulation; liver cancer and NASH; liver cancer and virus; liver cancer and immunology; liver cancer and 3D environment; liver cancer and microbiome
(This special issue belongs to the Section Molecular Oncology)
The Multiple Faces of Non-small Cell Lung Cancer: Targeted Therapies and Recent Developments
edited by Angelo Delmonte and Alberto Verlicchi
submission deadline 20 Sep 2024 | 1 articles | Viewed by 1220 | Submission Open
Keywords: non-small cell lung cancer; tyrosine-kinase inhibitors; next generation sequencing; immunoconjugates; targeted therapies 
(This special issue belongs to the Section Molecular Oncology)
Molecular Insight into Approaches against Cystic Fibrosis Infections
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 1143 | Submission Open
Keywords: cystic fibrosis; infections; multi-drug resistant pathogens; new drugs; anti-virulence compounds; phage therapy; vaccines
(This special issue belongs to the Section Molecular Microbiology)
Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases: 2nd Edition
edited by Joseph E. Deweese and Neil Osheroff
submission deadline 20 Sep 2024 | 1 articles | Viewed by 1105 | Submission Open
Keywords: topoisomerase; DNA supercoiling; DNA topology; anticancer; antimicrobial; DNA damage
(This special issue belongs to the Section Molecular Biology)
Natural Bioactives and Inflammation, 2nd Edition
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 1076 | Submission Open
Keywords: inflammation; bioactive compounds; polyphenols; nutraceutical; diet; nutrition; pharmacology; health; lifespan; healthspan; aging; inflammaging
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Research on Osteogenesis submission deadline 20 Sep 2024 | 1 articles | Viewed by 998 | Submission Open
Keywords: osteogenesis; bone reconstruction; bone regeneration; bone disease
(This special issue belongs to the Section Molecular Biology)
Editorial Board Members’ Collection Series: “Molecular Research on Neuroprotection” submission deadline 20 Sep 2024 | 1 articles | Viewed by 952 | Submission Open
Keywords: neuronal connectivity; neurotrophic factor signalling; liquid– liquid phase separation (LLPS); Ras/MAPK signaling; rasopathy; protein phosphatase 2A; Bax/Bad; NFκ B Signal-cascade; ubiquitin system; mitochondrial homeostasis; protein quality control; Alzheimer; taupathy; Parkinson; Nurr1; synuclein
(This special issue belongs to the Section Molecular Neurobiology)
New Advances in Myocardial Regeneration: Molecular Mechanisms and Promising Approaches
edited by
submission deadline 20 Sep 2024 | 1 articles | Viewed by 894 | Submission Open
Keywords: myocardial regeneration; transplantation of cells; proliferation of cardiomyocytes; 3D bioprinting; single cell omics; exosome delivery; cardiac organoids; direct reprogramming
(This special issue belongs to the Section Molecular Biology)
Molecular Research on Nanosorbent Materials submission deadline 20 Sep 2024 | 1 articles | Viewed by 783 | Submission Open
Keywords: adsorption; adsorbents; nanomaterials; insight at the molecular level; experimental studies; theoretical studies; fundamentals; applications
(This special issue belongs to the Section Materials Science)
Molecular Insight into Polymer Materials
edited by Namil Kim
submission deadline 20 Sep 2024 | Viewed by 730 | Submission Open
Keywords: adhesives; biopolymers; elastomers; nanocomposites; numerical analysis; molecular design; polymer chemistry; polymer physics; rheology and processing; surface coating
(This special issue belongs to the Section Materials Science)
Genomic Research in Neurobiology
edited by and Katerina Papanikolopoulou
submission deadline 20 Sep 2024 | 1 articles | Viewed by 617 | Submission Open
Keywords: neuro-omics; GWAS; single-neuron approaches; neurodegenerative -omics; psychiatric -omics; omics validation models and systems
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Pathways and New Therapies for Breast Cancer
edited by
submission deadline 20 Sep 2024 | Viewed by 583 | Submission Open
Keywords: breast cancer; cell signaling; molecular heterogeneity; targeted therapies; HER2; biomarkers
(This special issue belongs to the Section Molecular Biology)
Effect of Apolipoproteins on Infectious Diseases and Inflammatory Processes submission deadline 20 Sep 2024 | Viewed by 468 | Submission Open
Keywords: apolipoproteins; lipoproteins; intestinal microbiota; gut-liver axis; inflammation; cholesterol; toll-like receptors
(This special issue belongs to the Section Molecular Immunology)
50th Anniversary of the Molten Globule Prediction: The Impact on the Protein Folding Problem submission deadline 20 Sep 2024 | Viewed by 466 | Submission Open
Keywords: protein folding; cotranslational folding; chaperone-assisted folding; protein denaturation; protein unfolding; protein refolding; partially folded protein; folding intermediate; molten globule; protein misfolding; protein aggregation; conformational disease
(This special issue belongs to the Section Molecular Biophysics)
Recent Advances in the Immunopathology, Diagnostic Biomarkers, Susceptibility and Potential Therapies for Adverse Reactions to Food
edited by
submission deadline 20 Sep 2024 | Viewed by 456 | Submission Open
Keywords: adverse reactions to food; food intolerance; food allergy; gastrointestinal tract disorders; food hypersensitivity classification
(This special issue belongs to the Section Molecular Immunology)
The Molecular and Cellular Aspects of Insulin Resistance submission deadline 20 Sep 2024 | Viewed by 442 | Submission Open
Keywords: insulin resistance; insulin receptor; IRS; Akt; PI3K; protein phosphorylation; protein dephosphorylation; inflammation; metabolic syndrome; cardiometabolic syndrome; diabetic cardiomyopathy
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Immunomodulatory Activities of Natural Products and Related Compounds in Inflammatory Diseases
edited by Horyue Tan
submission deadline 20 Sep 2024 | Viewed by 439 | Submission Open
Keywords: immunomodulatory; natural products; inflammatory diseases; chronic inflammation
(This special issue belongs to the Section Molecular Immunology)
Lung Cancer: From Molecular Basis to Genome-Guided Therapy and Immunotherapy, 2nd Edition submission deadline 20 Sep 2024 | Viewed by 415 | Submission Open
Keywords: lung cancer; molecular pathology; molecular diagnosis; biomarker-driven therapy; immunotherapy; immune checkpoint inhibitors; personalized tumor therapy; cancer diagnosis
(This special issue belongs to the Section Molecular Oncology)
Molecular Insights in Bacterial Cellulose submission deadline 20 Sep 2024 | Viewed by 394 | Submission Open
Keywords: microbial cellulose; scaffolds; biomaterials; functional food; wound dressing; prebiotics; functional textile; microbial cellulose; scaffolds; biomaterials; functional food; wound dressing; prebiotics; functional textile
(This special issue belongs to the Section Materials Science)
Research on the Growth and Development of Germ Cells
edited by
submission deadline 20 Sep 2024 | Viewed by 382 | Submission Open
Keywords: follicle development; premature ovarian insufficiency; signal transduction; apoptosis autophagy; aging; reproductive biotechnology; organ-on-chip
(This special issue belongs to the Section Molecular Biology)
Advances and Perspectives in Molecular Tumor Therapy
edited by
submission deadline 20 Sep 2024 | Viewed by 357 | Submission Open
Keywords: tumorigenesis; immunotherapy; targeted therapy; tumor microenvironment; anti-cancer drugs
(This special issue belongs to the Section Molecular Oncology)
Toxic Effects of Cancer Treatments: Update on Targeted Molecular Approaches and Signalling Pathways
edited by and Éric Morel
submission deadline 20 Sep 2024 | Viewed by 355 | Submission Open
Keywords: radiotherapy; cancer treatment; chemotherapy; toxicities; hormone therapy; molecular signaling pathway
(This special issue belongs to the Section Molecular Toxicology)
Molecular and Epigenetic Regulation in Seed Development
edited by and Qingyun Bu
submission deadline 20 Sep 2024 | Viewed by 348 | Submission Open
Keywords: seed development; molecular mechanism; epigenetic modification; gene function; genetic improvement  
(This special issue belongs to the Section Molecular Plant Sciences)
Rejuvenation of Cells in Human Health and Diseases
edited by Stina Simonsson
submission deadline 20 Sep 2024 | Viewed by 345 | Submission Open
Keywords: cell rejuvenation; rejuvenation pathways; stem cell; osteoarthritis; cartilage regeneration; joint repair
(This special issue belongs to the Section Molecular Biology)
Molecular Materials for Functional Textile Coatings
edited by
submission deadline 20 Sep 2024 | Viewed by 341 | Submission Open
Keywords: smart textiles; electronic textiles; medical textiles; protective textiles; nano-finishing
(This special issue belongs to the Section Materials Science)
IQSEC2 Mediated Diseases: From Mechanisms to Treatment
edited by
submission deadline 20 Sep 2024 | Viewed by 338 | Submission Open
Keywords: IQSEC2; epilepsy; autism; intellectual disability; animal model; gene therapy; pharmacogenomics
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advanced Research in Mitochondrial Genetics
edited by
submission deadline 20 Sep 2024 | Viewed by 322 | Submission Open
Keywords: mitochondrial DNA sequencing; whole-exome sequencing; whole-genome sequencing; single-cell-sequencing; formalin-fixed-paraffin-embedded tissues; spatial-whole-transcriptomics; mitochondrial diseases
(This special issue belongs to the Section Molecular Biology)
The Role of Phenolic Compounds and Metabolites in Human Health submission deadline 20 Sep 2024 | Viewed by 320 | Submission Open
Keywords: phenolic compounds; phenolic metabolites; cardiovascular diseases; cancer; diabetes; colon metabolism; microbiota; cell culture; clinical studies
(This special issue belongs to the Section Bioactives and Nutraceuticals)
New Insights into Mitochondria in Health and Diseases submission deadline 20 Sep 2024 | Viewed by 310 | Submission Open
Keywords: mitochondrial bioenergetics; reactive oxygen species; apoptosis; aging; immune function; mtDNA mutations; mitochondrial dysfunction; mitochondria-targeted therapies
(This special issue belongs to the Section Biochemistry)
Skeletal Muscle Metabolism—Effects of Diet, Exercise and Pharmacotherapies
edited by
submission deadline 20 Sep 2024 | Viewed by 295 | Submission Open
Keywords: energy metabolism; metabolic signaling pathways; metabolic homeostasis; metabolic disorders; muscle mass; muscle metabolites; diet; exercise; pharmacotherapies
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Insight on Nanoparticle Toxicity
edited by Fátima Brandão
submission deadline 20 Sep 2024 | Viewed by 288 | Submission Open
Keywords: nanoparticles; toxicity; mechanisms; safe-by-design; molecular pathways; 3R principles
(This special issue belongs to the Section Molecular Nanoscience)
Recent Advances and Insights in Treatment of Urinary Tract Diseases
edited by Cheng-Yu Long
submission deadline 20 Sep 2024 | Viewed by 279 | Submission Open
Keywords: pathophysiology of UTD; UTD treatment modality; new therapeutic approaches and its basic mechanism; medication management of UTD; estrogen deprivation and UTD; bench work of lower urinary tract dysfunction; new advances in treatment of UTD
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Applications of Multi-omics Technologies to Comprehend Properties and Functions of Probiotics submission deadline 20 Sep 2024 | Viewed by 269 | Submission Open
Keywords: microbiology; food; probiotics; antimicrobial peptides; omics technologies; Whole Genome Sequencing (WGS); transcriptomics; bioinformatics
(This special issue belongs to the Section Molecular Microbiology)
Exploring Abiotic Stress in Plants: Mechanisms, Adaptations, and Mitigation Strategies
edited by
submission deadline 20 Sep 2024 | Viewed by 266 | Submission Open
Keywords: abiotic stress; plant physiology; stress tolerance; crop resilience; molecular mechanisms; biotechnological interventions
(This special issue belongs to the Section Molecular Plant Sciences)
New Insights into Lipids and Immune Responses
edited by Adam Shahine
submission deadline 20 Sep 2024 | Viewed by 266 | Submission Open
Keywords: immune system; lipids; antigen presentation; T-cell responses; bacterial infection; autoimmunity; inflammation
(This special issue belongs to the Section Molecular Immunology)
Glycobiology in Human Health and Disease
edited by Katrin Mani
submission deadline 20 Sep 2024 | Viewed by 263 | Submission Open
Keywords: glycans and glycoconjugates; glycoproteins; proteoglycans; glycolipids; glycosylation including glycosyltransferases and glycosidases; carbohydrate and glycan metabolism; glycan structure; disease biomarkers; glycan signaling; glycoimmunology; glycomics
(This special issue belongs to the Section Macromolecules)
The Role of Genome in Cancer Therapy
edited by Yoav Smith and Hovav Nechushtan
submission deadline 20 Sep 2024 | Viewed by 250 | Submission Open
Keywords: genome analysis; molecular therapy; drug resistance; cancer genetic
(This special issue belongs to the Section Molecular Genetics and Genomics)
Coumarins as Effective Therapeutic Agents: Mechanism of Action and Diverse Activity
edited by
submission deadline 20 Sep 2024 | Viewed by 230 | Submission Open
Keywords: furanocoumarins; pyranocoumarins; simple coumarins; anti-inflammatory properties; cytotoxic activity; antitumor activity; antimicrobial acitivity; bioactivity of compounds; anxiolytic activity; neuroprotective properties; bioactive metabolites; medicinal plants
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cardiovascular Diseases: From Molecular Mechanisms to Innovative Therapeutics submission deadline 20 Sep 2024 | Viewed by 225 | Submission Open
Keywords: cardiovascular diseases; diabetes; hypertension; obesity; venous thromboembolism; pulmonary embolism; deep vein thrombosis; bleeding; coagulation; clotting factor
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Lipopolysaccharide in the Health and Disease
edited by and Hiroyuki Inagawa
submission deadline 20 Sep 2024 | Viewed by 218 | Submission Open
Keywords: usefulness of LPS; oral and/or dermal administration of LPS; lifestyle disease; cognitive dysfunction; allergy; autoimmune disorder; wound healing; cancer
(This special issue belongs to the Section Biochemistry)
Lipid Metabolism and Biomarkers in Neural and Cardiometabolic Health
edited by
submission deadline 20 Sep 2024 | Viewed by 211 | Submission Open
Keywords: lipid species; cardiovascular health; neural health; inflammation; cardiac biomarkers; neural biomarkers
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Cellular and Molecular Mechanisms of Autoimmune Disorders
edited by
submission deadline 20 Sep 2024 | Viewed by 211 | Submission Open
Keywords: autoimmune diseases; self-tolerance; immune cells; autoantibodies; autoantigens; pathomechanisms
(This special issue belongs to the Section Molecular Immunology)
Prebiotics and Probiotics: Healthy Biotools for Molecular Integrative and Modulation Approaches—3rd Edition submission deadline 20 Sep 2024 | Viewed by 199 | Submission Open
Keywords: prebiotics; probiotics; molecular microbiology; immunology; microbiome
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Plant Metabolites with Pro-cognitive and Neuroprotective Effects submission deadline 20 Sep 2024 | Viewed by 196 | Submission Open
Keywords: neuroprotection; cognitive impairment; plant secondary metabolites; Alzheimer’ s disease; memory deficits; ADME
(This special issue belongs to the Section Bioactives and Nutraceuticals)
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