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Neurology International
Special Issues
Migraines and Beyond: Advances in the Pathogenesis and Treatment of...
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Migraines and Beyond: Advances in the Pathogenesis and Treatment of Chronic Headache Disorders, Second Edition

A special issue of Neurology International (ISSN 2035-8377).

Deadline for manuscript submissions: 30 September 2024 | Viewed by 546

Special Issue Editor

Prof. Dr. Yasushi Shibata

E-Mail Website
Guest Editor
Faculty of Medicine, Mito Medical Center, University of Tsukuba, Tsukuba, Japan
Interests: migraine; headache; molecular marker; imaging; pathology; CGRP; medical treatment; neuro-modulation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Migraine and headache are highly prevalent diseases; however, the pathogenesis of these primary headache disorders has not been completely revealed. Recent advances and clinical applications of CGRP-blocking therapies have provided great advances for both basic and clinical research of headaches.

We are pleased to invite you to contribute to this Special Issue. This Special Issue aims to collect cutting-edge findings on migraine. In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: molecular pathophysiology, imaging, medical therapy, neuromodulation, animal studies, and clinical studies.

I look forward to receiving your contributions.

Prof. Dr. Yasushi Shibata
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Neurology International is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • migraine
  • headache
  • molecular marker
  • imaging
  • pathology
  • CGRP
  • medical treatment
  • neuromodulation

Published Papers (1 paper)

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8 pages, 2007 KiB  
Case Report
A Case of Idiopathic Intracranial Hypertension Complicated with both Infratentorial and Supratentorial Cortical Superficial Siderosis: Novel Imaging Findings on Intravoxel Incoherent Motion Magnetic Resonance Imaging Offering Clues to Pathophysiology
by Shinya Watanabe, Yasushi Shibata and Eiichi Ishikawa
Neurol. Int. 2024, 16(4), 701-708; https://doi.org/10.3390/neurolint16040053 - 28 Jun 2024
Viewed by 324
Abstract
The pathology of idiopathic intracranial hypertension (IIH), a disease characterized by papillary edema and increased intracranial pressure (IICP), is not yet understood; this disease significantly affects quality of life due to symptoms including vision loss, headache, and pulsatile tinnitus. By contrast, superficial siderosis [...] Read more.
The pathology of idiopathic intracranial hypertension (IIH), a disease characterized by papillary edema and increased intracranial pressure (IICP), is not yet understood; this disease significantly affects quality of life due to symptoms including vision loss, headache, and pulsatile tinnitus. By contrast, superficial siderosis (SS), a disorder in which hemosiderin is deposited on the surface of the cerebral cortex and cerebellum, potentially causes cerebellar ataxia or hearing loss. So far, no cases of IIH with infratentorial and supratentorial cortical SS have been reported. Herein, we report a case of a 31-year-old woman with obesity who developed this condition. The patient suddenly developed headache and dizziness, had difficulty walking, and subsequently became aware of diplopia. Fundus examination revealed bilateral optic nerve congestive papillae and right eye abducens disturbance. Head magnetic resonance imaging (MRI) showed prominent SS on the cerebellar surface and cerebral cortex. Lumbar puncture revealed IICP of 32 cmH2O, consistent with the diagnostic criteria for IIH, and treatment with oral acetazolamide was started; subsequently, the intracranial pressure decreased to 20 cmH2O. Her abduction disorder disappeared, and the swelling of the optic papilla improved. She was now able return to her life as a teacher without any sequelae. SS is caused by persistent slight hemorrhage into the subarachnoid space. In this case, both infratentorial and supratentorial cortical superficial SS was observed. Although cases of IIH complicated by SS are rare, it should be kept in mind that a causal relationship between IIH and SS was inferred from our case. Our findings also suggest that cerebrospinal fluid dynamic analysis using MRI is effective in diagnosing IIH and in determining the efficacy of treatment. Full article
(This article belongs to the Special Issue Migraines and Beyond: Advances in the Pathogenesis and Treatment of Chronic Headache Disorders, Second Edition)
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