The Role of Fatty Acids in Inflammation
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".
Deadline for manuscript submissions: 5 September 2025 | Viewed by 1294
Special Issue Editor
Interests: fatty acid metabolism; elongation and desaturarion of polyunsaturated fatty acids (PUFAs); n-3 PUFAs in diet and health; fatty acid and oxidative stress; fatty acid and inflammatory response; fatty acid in health or disease
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Special Issue Information
Dear Colleagues,
Fatty acids (saturated, mono, or polyunsaturated) have key roles in many cellular processes, such as membrane structure, energy status, gene expression, cellular differentiation, apoptosis, etc. Additionally, fatty acids exhibit important functions in mammals in different stages of the life cycle (embryonal and fetal development, growing, and aging), as well as in the prevention or development of various diseases. Over the last two decades, several researchers have investigated the participation of fatty acids, or the molecules derived from fatty acids (lipid mediators), in the inflammatory response, specifically in the activation and resolution of this physiological process. Inflammation is an essential process to the cellular defense against different injuries, but under/overnutrition (obesity) or aging conditions cause inflammation to have a fundamental participation in the development of physiopathological damages. The proposal of this Special Issue about the role of fatty acids in inflammation as its principal focus presents a coherent view on the participation of FAs in the activation of the inflammatory response or in its resolution. It considers (i) molecular pathways involved in these processes, or (ii) topics such as obesity, diabetes, cancer, cardiovascular, neurodegenerative, and autoimmune respiratory diseases.
Dr. Rodrigo Valenzuela
Guest Editor
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Keywords
- fatty acids
- saturated fatty acids
- monounsaturated fatty acids
- polyunsaturated fatty acids (PUFAs)
- n-3 or n-6 PUFAs
- fatty acids and diet
- inflammation
- inflammatory response
- resolution of inflammation
- fatty acids, oxidative stress and inflammation
- chronic disease
- aging
- health
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