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Nutrients
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Impact of Lipids and Adipose Tissue on Health and Diseases
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Impact of Lipids and Adipose Tissue on Health and Diseases

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".

Deadline for manuscript submissions: 20 May 2025 | Viewed by 639

Special Issue Editors

Dr. Tongxing Song

E-Mail Website
Guest Editor
College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China
Interests: stem cell fate; adipogenesis; lipid droplet; lipid metabolism; organs crosstalk
Special Issues, Collections and Topics in MDPI journals
Dr. Zhihao Jia

E-Mail Website
Guest Editor
Cambridge-Suda Genomic Resource Center, Soochow University, Suzhou 215123, China
Interests: adipocytes; lipid metabolism; protein modification; thermogenesis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Currently, humanity is facing an increasing number of lifestyle-related diseases, such as obesity, insulin resistance, diabetes mellitus, and alcoholic fatty liver disease, which are closely related to lipid metabolism. Lipids play a crucial role in the physiological functioning of the body, serving as critical elements in the regulation of energy homeostasis, endocrine balance, and cellular communication pathways. Hence, it is of great significance to understand the role of lipid metabolism in health and disease. Intestines, adipose tissue, liver, muscle, and other tissues are the key organs in lipid metabolism, playing important roles in the digestion, absorption, transport, excretion, and deposition of lipids. However, many mechanisms related to lipid metabolism are still not fully elucidated. Clarifying the mechanisms of lipid metabolism can be beneficial for providing diagnostic and therapeutic insights for major metabolic diseases in humans.

Therefore, this Special Issue aims to encourage authors to submit original research articles and review papers related to adipose tissue development and lipid metabolism in human health and diseases as well as related animal models.

The research topics include, but are not limited to, the following:

  1. Lipid metabolism in the intestine;
  2. Mechanisms of adipogenesis and lipolysis;
  3. Crosstalk between adipose tissue and other organ tissues;
  4. Dietary nutrients targeting lipid metabolism for the regulation of health and homeostasis;
  5. Lipid metabolism and nutritional regulation in health and diseases.

Dr. Tongxing Song
Dr. Zhihao Jia
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dietary lipid
  • lipid metabolism
  • adipogenesis
  • lipolysis
  • homeostatsis

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Published Papers (1 paper)

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Research

27 pages, 2563 KiB  
Article
Visceral Fat, Metabolic Health, and Lifestyle Factors in Obstructive Bronchial Diseases: Insights from Bioelectrical Impedance Analysis
by Ștefana-Oana Popescu, Andreea Mihai, Adina Turcu-Știolică, Carmen Elena Lupu, Diana-Maria Cismaru, Victor Ionel Grecu, Alexandru Scafa-Udriște, Răzvan Ene and Magdalena Mititelu
Nutrients 2025, 17(6), 1024; https://doi.org/10.3390/nu17061024 - 14 Mar 2025
Viewed by 477
Abstract
Background/Objectives: This study examines the relationship between visceral fat (VF), metabolic health, and dietary patterns in patients with obstructive bronchial diseases (OBDs) using bioelectrical impedance analysis (BIA). Methods: A total of 75 patients diagnosed with OBD, including chronic obstructive pulmonary disease [...] Read more.
Background/Objectives: This study examines the relationship between visceral fat (VF), metabolic health, and dietary patterns in patients with obstructive bronchial diseases (OBDs) using bioelectrical impedance analysis (BIA). Methods: A total of 75 patients diagnosed with OBD, including chronic obstructive pulmonary disease (COPD) and/or asthma, were assessed for VF levels via BIA. Dietary habits were evaluated using a structured questionnaire to explore their correlation with VF accumulation. Results: The study cohort comprised predominantly male participants (66.7%), with the majority aged between 61 and 70 years (46.7%). Significant gender differences in VF distribution were observed, with 60% of females maintaining normal VF levels (1–9) compared to only 28% of males, while 38% of males exhibited very high VF levels (15–30; p = 0.003). Body mass index (BMI) showed a strong correlation with VF (p < 0.0001), as overweight and obese individuals predominantly displayed elevated VF levels (≥10). Moreover, metabolic syndrome (MS) was present in 66.7% of participants, with these individuals exhibiting significantly higher VF levels compared to those without MS (p = 0.001). Dietary analysis revealed that frequent consumption of fast food (r = 0.717, p < 0.001), carbonated drinks (r = 0.366, p = 0.001), and refined carbohydrates (r = 0.438, p < 0.001) was significantly associated with increased VF accumulation. Conversely, higher intake of water (r = −0.551, p < 0.001), fruits (r = −0.581, p < 0.001), and vegetables (r = −0.482, p < 0.001) correlated with lower VF levels. Lack of physical activity was also strongly linked to VF accumulation (r = 0.481, p < 0.001), further reinforcing the role of lifestyle factors in metabolic health. Conclusions: The findings underscore the significant impact of dietary habits and physical activity on VF accumulation in OBD patients. BMI and MS emerged as critical predictors of VF, while unhealthy dietary patterns and sedentary lifestyles further exacerbated VF deposition. Elevated VF levels were linked to adverse lipid profiles, reinforcing the need for dietary and lifestyle modifications in managing metabolic health among OBD patients. Although no direct association was identified between VF and forced expiratory volume in one second (FEV1), the results highlight the necessity of integrated nutritional and metabolic interventions in the management of chronic respiratory diseases. Full article
(This article belongs to the Special Issue Impact of Lipids and Adipose Tissue on Health and Diseases)
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