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The Intervention of Diet on Energy Metabolism

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: closed (20 December 2022) | Viewed by 10003

Special Issue Editors


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Guest Editor
Immunometabolism, Department of Nutrition, Nursing School, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Brazil
Interests: intermediary metabolism; adipose tissue remodeling; dietary compositions and immunometabolism

E-Mail Website
Guest Editor
Immunometabolism, Department of Nutrition, Nursing School, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Brazil
Interests: dietary compositions; immunometabolism; bone remodeling and arthritis

Special Issue Information

Dear Colleagues,

Food intake patterns determine changes in energy expenditure due to its influence on body size and composition (percentage of fat, bone, and muscle) which can modulate signalling pathways that optimise the consumption of energy. On the other hand, energy restriction may cause an adaptive reduction in energy expenditure by lowering tissue metabolism and reducing body movement.

Articles focusing on the effect of diet profile, nutrient supplementation, and/or eating habits on the energy metabolism, mainly the energy expenditure in metabolic disorders of any type, are welcomed. We include original articles, reviews, and meta-analyses with particular focus on the role of specific nutrients or supplements in pathogenic and physiological processes linked to energy metabolism.

Main Topics (but not limited to):

  • The effect of nutrients (e.g., amino acids, glucose, fructose, lipids, vitamins, and minerals) on energy expenditure;
  • Functional food as a strategy to influence energy expenditure;
  • The importance of the oral microbiome in the modulation of energy metabolism;
  • The role of mediators of inflammation on energy metabolism;
  • The effect of hormones in the regulation of energy metabolism;
  • The impact of body composition in the energy expenditure;
  • The impact of diet on energy metabolism in acute and chronic diseases;
  • Eating strategies to modulate energy expenditure.

Dr. Adaliene Versiani Matos Ferreira
Prof. Dr. Marina Chaves De Oliveira
Guest Editors

Manuscript Submission Information

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Keywords

  • energy
  • metabolism
  • diet
  • nutrients
  • supplements

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Published Papers (4 papers)

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Editorial

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2 pages, 182 KiB  
Editorial
The Intervention of Diet on Energy Metabolism
by Marina C. Oliveira and Adaliene V. M. Ferreira
Nutrients 2023, 15(11), 2544; https://doi.org/10.3390/nu15112544 - 30 May 2023
Cited by 1 | Viewed by 1512
Abstract
Food intake patterns determine changes in energy expenditure due to their influence on body size and composition (percentage of fat, bone, and muscle), which can modulate signaling pathways that optimize energy consumption [...] Full article
(This article belongs to the Special Issue The Intervention of Diet on Energy Metabolism)

Research

Jump to: Editorial

18 pages, 2999 KiB  
Article
Nutritional Programming of the Lifespan of Male Drosophila by Activating FOXO on Larval Low-Nutrient Diet
by Yue Gao, Xingyi Cheng, Yao Tian, Zhixiao Yuan, Xiaolan Fan, Deying Yang and Mingyao Yang
Nutrients 2023, 15(8), 1840; https://doi.org/10.3390/nu15081840 - 11 Apr 2023
Cited by 3 | Viewed by 2536
Abstract
Nutrition during the developmental stages has long-term effects on adult physiology, disease and lifespan, and is termed nutritional programming. However, the underlying molecular mechanisms of nutritional programming are not yet well understood. In this study, we showed that developmental diets could regulate the [...] Read more.
Nutrition during the developmental stages has long-term effects on adult physiology, disease and lifespan, and is termed nutritional programming. However, the underlying molecular mechanisms of nutritional programming are not yet well understood. In this study, we showed that developmental diets could regulate the lifespan of adult Drosophila in a way that interacts with various adult diets during development and adulthood. Importantly, we demonstrated that a developmental low-yeast diet (0.2SY) extended both the health span and lifespan of male flies under nutrient-replete conditions in adulthood through nutritional programming. Males with a low-yeast diets during developmental stages had a better resistance to starvation and lessened decline of climbing ability with age in adulthood. Critically, we revealed that the activity of the Drosophila transcription factor FOXO (dFOXO) was upregulated in adult males under developmental low-nutrient conditions. The knockdown of dFOXO, with both ubiquitous and fat-body-specific patterns, can completely abolish the lifespan-extending effect from the larval low-yeast diet. Ultimately, we identify that the developmental diet achieved the nutritional programming of the lifespan of adult males by modulating the activity of dFOXO in Drosophila. Together, these results provide molecular evidence that the nutrition in the early life of animals could program the health of their later life and their longevity. Full article
(This article belongs to the Special Issue The Intervention of Diet on Energy Metabolism)
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20 pages, 2869 KiB  
Article
Effects of Intermittent Fasting on Hypothalamus–Pituitary–Thyroid Axis, Palatable Food Intake, and Body Weight in Stressed Rats
by Cinthia García-Luna, Ixchel Prieto, Paulina Soberanes-Chávez, Elena Alvarez-Salas, Iván Torre-Villalvazo, Gilberto Matamoros-Trejo and Patricia de Gortari
Nutrients 2023, 15(5), 1164; https://doi.org/10.3390/nu15051164 - 25 Feb 2023
Cited by 4 | Viewed by 3000
Abstract
Dietary regimens that are focused on diminishing total caloric intake and restricting palatable food ingestion are the most common strategies for weight control. However, restrictive diet therapies have low adherence rates in obese patients, particularly in stressed individuals. Moreover, food restriction downregulates the [...] Read more.
Dietary regimens that are focused on diminishing total caloric intake and restricting palatable food ingestion are the most common strategies for weight control. However, restrictive diet therapies have low adherence rates in obese patients, particularly in stressed individuals. Moreover, food restriction downregulates the hypothalamic–pituitary–thyroid axis (HPT) function, hindering weight loss. Intermittent fasting (IF) has emerged as an option to treat obesity. We compared the effects of IF to an all-day feeding schedule on palatable diet (PD)-stress (S)-induced hyperphagia, HPT axis function, accumbal thyrotropin-releasing hormone (TRH), and dopamine D2 receptor expression in association with adipocyte size and PPARƔ coactivator 1α (PGC1α) and uncoupling protein 1 (UCP1) expression in stressed vs. non-stressed rats. After 5 weeks, S-PD rats showed an increased energy intake and adipocyte size, fewer beige cells, and HPT axis deceleration-associated low PGC1α and UCP1 expression, as well as decreased accumbal TRH and D2 expression. Interestingly, IF reversed those parameters to control values and increased the number of beige adipocytes, UCP1, and PGC1α mRNAs, which may favor a greater energy expenditure and a reduced body weight, even in stressed rats. Our results showed that IF modulated the limbic dopaminergic and TRHergic systems that regulate feeding and HPT axis function, which controls the metabolic rate, supporting this regimen as a suitable non-pharmacologic strategy to treat obesity, even in stressed individuals. Full article
(This article belongs to the Special Issue The Intervention of Diet on Energy Metabolism)
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13 pages, 2011 KiB  
Article
The Effects of Alpha-Glycerylphosphorylcholine on Heart Rate Variability and Hemodynamic Variables Following Sprint Interval Exercise in Overweight and Obese Women
by Seyedeh Parya Barzanjeh, Linda S. Pescatello, Arturo Figueroa and Sajad Ahmadizad
Nutrients 2022, 14(19), 3970; https://doi.org/10.3390/nu14193970 - 24 Sep 2022
Cited by 2 | Viewed by 2524
Abstract
The current study examined the effects of Alpha-Glycerylphosphorylcholine (A-GPC) on heart rate variability (HRV) and hemodynamic responses following a sprint interval exercise (SIE) in women who were overweight or obese. Participants (n = 12, 31.0 ± 4.6 years; 29.4 ± 2.1 kg/m [...] Read more.
The current study examined the effects of Alpha-Glycerylphosphorylcholine (A-GPC) on heart rate variability (HRV) and hemodynamic responses following a sprint interval exercise (SIE) in women who were overweight or obese. Participants (n = 12, 31.0 ± 4.6 years; 29.4 ± 2.1 kg/m2) consumed 1000 mg of A-GPC or a placebo after eating breakfast in a randomized, double-blind cross-over design. After 60 min, participants performed two bouts of the SIE (30 s Wingate) interspersed with 4 min of active recovery (40 rpm). Hemodynamic variables and HRV domains were measured before and 60 min after the A-GPC consumption, immediately after SIE, and every 15 min up to 120 min during recovery. A-GPC consumption increased resting levels of both the time domain (Standard Deviation of RR wave intervals [SDNN] and percentage of interval differences of adjacent RR intervals greater than 50 ms [pNN50%]) and frequency domain (high frequency [HF] and low frequency [LF]) variables of HRV (p < 0.05). Moreover, HRV variables (except for LF/HF) decreased (p < 0.05) immediately after SIE in the A-GPC and placebo sessions. Systolic and diastolic blood pressure increased (p < 0.05) immediately after SIE in both trials. Both HRV and hemodynamic variables recovered (p < 0.05) faster in the A-GPC compared to the placebo session. We concluded that A-GPC consumption recovers HRV and blood pressure faster following strenuous exercise in overweight and obese women, and that it might favorably modify cardiac autonomic function. Full article
(This article belongs to the Special Issue The Intervention of Diet on Energy Metabolism)
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