Improving the Bioavailability and Solubility of Pharmaceutical Formulations
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Physical Pharmacy and Formulation".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 1049
Special Issue Editors
Interests: pharmaceutical research and development; nanotechnology; permeability enhancement
Special Issues, Collections and Topics in MDPI journals
Interests: bioavailability enhancement; oral formulations; micro- and nanotechnology; peptide carriers; biocompatibility
Special Issue Information
Dear Colleagues,
In modern pharmacotherapy, there is an increasing demand to develop new pharmaceutical forms that can be safely administered with adequate bioavailability and patient compliance in order to achieve successful therapeutic responses. Bioavailability is essential in the development of new drugs and formulations. More effective and efficient active ingredients can be designed by understanding the factors that affect bioavailability, such as solubility, chemical stability, and pharmaceutical forms. This leads to innovative drugs with higher bioavailability and a better therapeutic profile. In order to reach the site of action and achieve the required pharmacological effect, drugs have to face biological membranes, regardless of the route of administration. Overall, many methods and innovative dosage forms have been developed in the last decade to overcome these challenges.
This Special Issue aims to highlight the key aspects of recent techniques and methods used to improve the bioavailability of active pharmaceutical ingredients, as well as enhance the solubility and dissolution of poorly soluble pharmacons. In this Special Issue, we welcome researchers to contribute original research and review articles relevant to this topic.
We look forward to receiving your contributions.
Dr. Zoltan Ujhelyi
Dr. Dóra Kósa
Dr. Ágota Pető
Guest Editors
Manuscript Submission Information
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Keywords
- bioavailability enhancement
- drug delivery systems
- in vitro and in vivo evaluation methods
- therapeutic effectiveness
- pharmaceutical innovations
- nanoformulations
- surfactants
- poorly soluble drugs
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