New Advances in Addiction Behavior

Abstract submission deadline

1 January 2026

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1 March 2026

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Topic Information

Dear Colleagues,

Addictions present a complex challenge, given that they involve crucial behavioral and psychological aspects. In the effort to address this, a large body of literature has highlighted the importance of unearthing the motivations underlying the development and maintenance of addictions, emphasizing the need for a dual approach that is both cognitive and emotional. In this context, interdisciplinary research emerges as a key element useful for understanding the topic of “addiction”, beginning with neuro-genetic, neuro-biological, neuro-psychological, and social roots.

The goal of this Topic is to highlight individualized prevention and intervention techniques in order to raise awareness, as well as prevent and challenge the development and maintenance of addiction with integrated and innovative approaches. As such, we welcome contributions related to the application of advanced technologies, such as artificial intelligence (AI) and machine learning (ML), that can advance the understanding of addiction-related behavioral patterns. Tools such as these will not only help identify early signs of addiction but also provide new approaches for personalized therapeutic intervention. 

Dr. Emanuela Mari
Dr. Laura Piccardi
Dr. Alessandro Quaglieri
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Behavioral Sciences behavsci	2.5	2.6	2011	28.7 Days	CHF 2200	Submit
Brain Sciences brainsci	2.7	4.8	2011	15.6 Days	CHF 2200	Submit
European Journal of Investigation in Health, Psychology and Education ejihpe	3.0	4.4	2011	26.9 Days	CHF 1400	Submit
Healthcare healthcare	2.4	3.5	2013	20.3 Days	CHF 2700	Submit
Journal of Clinical Medicine jcm	3.0	5.7	2012	16 Days	CHF 2600	Submit

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Published Papers (9 papers)

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15 pages, 246 KiB  

Open AccessProtocol

Suicide Risk in Alcohol Use Disorders: Literature Review and Study Protocol with Preliminary Data for a Study in Treatment-Seeking Inpatients

by Marika Krystkiewicz and Michael Soyka

Healthcare 2025, 13(5), 535; https://doi.org/10.3390/healthcare13050535 - 28 Feb 2025

Viewed by 997

Abstract

Background/Objectives: Individuals with substance use disorders are at risk of displaying suicidal behavior with suicide occurring more frequently compared to the general population. This article gives an overview of the existing literature on the association of substance use disorders, especially alcohol use disorder [...] Read more.

Background/Objectives: Individuals with substance use disorders are at risk of displaying suicidal behavior with suicide occurring more frequently compared to the general population. This article gives an overview of the existing literature on the association of substance use disorders, especially alcohol use disorder (AUD), with suicidal behavior. Studies indicate that individuals with AUD report a lifetime prevalence of 40% for at least one instance of attempted suicide. They also have a 10 to 14 times higher risk of suicidal behavior compared to the general population. Methods: The protocol and preliminary data from an ongoing study focused on the prevalence and clinical correlations of suicidal ideation and attempts in treatment-seeking inpatients with AUD are presented. The objective of this study is to address open questions regarding the clinical factors and psychiatric comorbidities associated with suicidality in patients with AUD. In a pilot and feasibility study in an inpatient rehabilitation facility for the treatment of substance use disorders, 150 patients with AUD were examined. For assessment, the Beck Depression Inventory (BDI-II), the Symptom Check-list-90 (SCL-90), and the Scale Suicidal Experience and Behavior (SSEV) were used as standardized questionnaires. In addition, psychosocial and sociodemographic variables were recorded. A total of 257 items were surveyed for each respondent. The statistical analysis was carried out using IBM SPSS. Results: The initial evaluation indicates the feasibility of the study with a high number of responders (90% response rate). Of the participants surveyed, 50.7% (N = 76) were at risk of suicide and 40.7% (N = 61) had already made at least one suicide attempt. Even with a small sample size, a significant, moderate-to-large correlation between alcohol use disorder and suicidality could be demonstrated. Conclusions: This confirms that suicidality is a risk factor for patients with AUD. The role of psychiatric comorbidity, clinical correlations and consequences of AUD, Gender and treatment outcome will be studied in a larger sample of 700 patients. Full article

(This article belongs to the Topic New Advances in Addiction Behavior)

15 pages, 278 KiB  

Open AccessReview

Exploring the Practice of Dual Vaping: Health Risks and Behavioral Patterns in Nicotine and Cannabis E-Cigarette Users

by Giovanna Nelda Vaccari Bongetta, Raony Ferreira França, Maria Olivia Pozzolo Pedro, Kae Leopoldo, Luiza Larrubia Alvares Florence, Israel Kanaan Blaas, Gislaine Koch Gimenes, Julio Torales, Antonio Ventriglio, Domenico de Berardis and João Mauricio Castaldelli-Maia

Brain Sci. 2025, 15(2), 97; https://doi.org/10.3390/brainsci15020097 - 21 Jan 2025

Viewed by 2353

Abstract

Background: E-cigarettes, initially designed for nicotine consumption, are now increasingly being used to smoke cannabis, resulting in a growing trend known as “dual vaping”. This term describes individuals, referred to as “dual users”, who use e-cigarettes for both substances. This study aims to [...] Read more.

Background: E-cigarettes, initially designed for nicotine consumption, are now increasingly being used to smoke cannabis, resulting in a growing trend known as “dual vaping”. This term describes individuals, referred to as “dual users”, who use e-cigarettes for both substances. This study aims to review and analyze existing research on dual vaping, with a focus on the associated health risks and behavioral patterns. Methods: A narrative review of the literature was conducted using PubMed. Studies focusing on individuals who use electronic cigarettes for vaping tobacco and cannabis, either chronically or episodically, were examined. Relevant articles were identified and thematically synthesized to provide a comprehensive overview of the topic. Results: Dual vaping was found to be prevalent among younger men, White and Hispanic populations, and individuals with higher economic status and educational level. The use of one substance was shown to predispose individuals to the use of the other, often leading to concurrent use of both substances. Peer influence and positive expectations regarding e-cigarettes were identified as significant predictors of dual use. Dual vapers exhibited a higher susceptibility to respiratory and systemic symptoms compared to those who exclusively vaped nicotine or cannabis. Moreover, a notable prevalence of psychiatric disorders, such as substance use disorders, anxiety, and depression, was observed in this group. Fruit-flavored e-cigarettes were the most preferred option among dual vapers when using both nicotine and cannabis. Conclusions: Current evidence is insufficient to fully elucidate the long-term impacts of dual vaping on physical and mental health, particularly when compared to individuals who have never vaped. Further studies are needed to gain a more comprehensive understanding of this behavior. Full article

(This article belongs to the Topic New Advances in Addiction Behavior)

27 pages, 701 KiB  

Open AccessArticle

Exploring the Intersection of Hegemonic Masculinity, Sexuality, and Addiction in Men: A Qualitative Study

by Julio A. Camacho-Ruiz, Carmen M. Galvez-Sánchez, Federica Galli and Rosa M. Limiñana-Gras

Healthcare 2025, 13(1), 5; https://doi.org/10.3390/healthcare13010005 - 24 Dec 2024

Viewed by 1462

Abstract

Background/Objectives: In our society, as well as in many other parts of the world, sexuality is shaped through gender-differentiated socialization. This process compels individuals to align their desires, behaviors, emotions, and thoughts with the expectations of normative sexuality, especially hegemonic heterosexuality. The primary [...] Read more.

Background/Objectives: In our society, as well as in many other parts of the world, sexuality is shaped through gender-differentiated socialization. This process compels individuals to align their desires, behaviors, emotions, and thoughts with the expectations of normative sexuality, especially hegemonic heterosexuality. The primary objective of this current research was to examine the influence of hegemonic masculinity on the sexuality of men struggling with addiction. Method: This study employed a qualitative approach, specifically using conventional content analysis. To ensure research quality and transparency, the study adhered to the Standards for Reporting Qualitative Research (SRQR) and the Consolidated Criteria for Reporting Qualitative Studies (COREQ). Fourteen participants from a therapeutic community for addiction treatment in Spain were selected through purposive sampling. Data collection involved semi-structured interviews, supplemented by participant observation. The sample size was determined based on the principle of data saturation. Results: The findings reveal that factors such as gender-differentiated socialization, particularly the values associated with hegemonic masculinity (e.g., the pressure to maintain constant sexual availability and sexual initiative), alongside excessive engagement with prostitution and pornography, are closely linked to substance abuse, the development of addictions, and the emergence of sexual dysfunctions in men. The study also highlights the role of challenges related to oppression rooted in heteronormativity—understood as the imposition of rigid norms governing sexual orientation and behavior—in shaping sexual problems and in the origin and maintenance of addictions in men. Conclusions: It is essential to implement an intervention strategy that promotes egalitarian masculinities within the treatment of men with addiction issues, emphasizing a biopsychosocial approach to sexuality that integrates a gender perspective. Additionally, it is crucial to incorporate gender-sensitive interventions into rehabilitation programs for both men and women, ensuring a comprehensive understanding of each group’s specific needs and fostering the development of healthy, equitable relationships in the context of addiction treatment. Full article

(This article belongs to the Topic New Advances in Addiction Behavior)

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14 pages, 675 KiB  

Open AccessArticle

Nature Connectedness Reduces Internet Gaming Disorder: The Chain Mediating Role of Intolerance of Uncertainty and Desire Thinking

by Zihui Yuan, Fang Xu and Qingqi Liu

Behav. Sci. 2024, 14(9), 844; https://doi.org/10.3390/bs14090844 - 19 Sep 2024

Cited by 1 | Viewed by 1665

Abstract

While online gaming has become a choice for relaxation and entertainment in today’s digital age, Internet Gaming Disorder (IGD) has also become a widely concerning mental disorder. Nature connectedness has been found to effectively reduce addiction-related risks and alleviate symptoms of addictive behaviors. [...] Read more.

While online gaming has become a choice for relaxation and entertainment in today’s digital age, Internet Gaming Disorder (IGD) has also become a widely concerning mental disorder. Nature connectedness has been found to effectively reduce addiction-related risks and alleviate symptoms of addictive behaviors. It is a relatively lacking but very important factor influencing psychological recovery and regulation in the digital society. This study aims to explore the relationship between nature connectedness and IGD, and the mediating roles of intolerance of uncertainty and desire thinking. A total of 571 young people voluntarily participated in the questionnaire survey. The results showed that: (1) nature connectedness was negatively correlated with IGD; (2) intolerance of uncertainty plays a mediating role between nature connectedness and IGD; and (3) intolerance of uncertainty and desire thinking plays a chain mediating role between nature connectedness and IGD. Analysis of the research results indicates that nature connectedness can effectively reduce IGD and reveal its mechanism of action. The findings provide new insights for the study and intervention of IGD in the digital age. Full article

(This article belongs to the Topic New Advances in Addiction Behavior)

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57 pages, 557 KiB  

Open AccessReview

Biomarkers of Internet Gaming Disorder—A Narrative Review

by Katarzyna Skok and Napoleon Waszkiewicz

J. Clin. Med. 2024, 13(17), 5110; https://doi.org/10.3390/jcm13175110 - 28 Aug 2024

Viewed by 1677

Abstract

Since game mechanics and their visual aspects have become more and more addictive, there is concern about the growing prevalence of Internet gaming disorder (IGD). In the current narrative review, we searched PubMed and Google Scholar databases for the keywords “igd biomarker gaming” [...] Read more.

Since game mechanics and their visual aspects have become more and more addictive, there is concern about the growing prevalence of Internet gaming disorder (IGD). In the current narrative review, we searched PubMed and Google Scholar databases for the keywords “igd biomarker gaming” and terms related to biomarker modalities. The biomarkers we found are grouped into several categories based on a measurement method and are discussed in the light of theoretical addiction models (tripartite neurocognitive model, I-PACE). Both theories point to gaming-related problems with salience and inhibition. The first dysfunction makes an individual more susceptible to game stimuli (raised reward seeking), and the second negatively impacts resistance to these stimuli (decreased cognitive control). The IGD patients’ hypersensitivity to reward manifests mostly in ventral striatum (VS) measurements. However, there is also empirical support for a ventral-to-dorsal striatal shift and transition from goal-directed to habitual behaviors. The deficits in executive control are demonstrated in parameters related to the prefrontal cortex (PFC), especially the dorsolateral prefrontal cortex (DLPFC). In general, the connection of PFC with reward under cortex nuclei seems to be dysregulated. Other biomarkers include reduced P3 amplitudes, high-frequency heart rate variability (HRV), and the number of eye blinks and saccadic eye movements during the non-resting state. A few studies propose a diagnostic (multimodal) model of IGD. The current review also comments on inconsistencies in findings in the nucleus accumbens (NAcc), anterior cingulate cortex (ACC), and precuneus and makes suggestions for future IGD studies. Full article

(This article belongs to the Topic New Advances in Addiction Behavior)

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12 pages, 538 KiB  

Open AccessArticle

Validation of an Instrument for Detecting Problematic Internet Use in Adolescents

by Mateo Pérez-Wiesner, Kora-Mareen Bühler and Jose Antonio López-Moreno

Behav. Sci. 2024, 14(8), 715; https://doi.org/10.3390/bs14080715 - 15 Aug 2024

Viewed by 1279

Abstract

Problematic internet use (PIU) has drawn attention due to its potentially negative consequences on individuals’ social and personal lives. At present, a consensus on diagnostic criteria for problematic internet use remains elusive, leaving uncertainty regarding its classification as a distinct mental disorder. Extensive [...] Read more.

Problematic internet use (PIU) has drawn attention due to its potentially negative consequences on individuals’ social and personal lives. At present, a consensus on diagnostic criteria for problematic internet use remains elusive, leaving uncertainty regarding its classification as a distinct mental disorder. Extensive research efforts are underway to investigate its underlying causes, risk factors, and correlated adverse consequences. Nonetheless, research on problematic internet use (PIU) frequently faces challenges due to the absence of consistent and dependable evaluation methods, with many existing assessment tools lacking a solid theoretical basis. This study introduces a novel instrument that incorporates positive emotional regulation along with negative emotional regulation, compulsive use, and cognitive preoccupation, all crucial aspects of PIU. The study involved 3054 adolescents from Madrid, Spain, and employed exploratory and confirmatory factor analyses to validate the instrument’s structure. The resulting four-factor model includes Positive Emotional Regulation, Negative Emotional Regulation, Compulsive Use, and Cognitive Preoccupation. The instrument demonstrates good internal consistency and an association with risk factors, as evidenced by correlations with time spent on various internet-related activities. This comprehensive tool enhances our understanding of PIU and its underlying cognitive and emotional processes and provides a valuable resource for assessing and addressing problematic internet use in adolescents. Full article

(This article belongs to the Topic New Advances in Addiction Behavior)

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18 pages, 7993 KiB  

Open AccessArticle

Exploring the Acute Effects of Immersive Virtual Reality Biking on Self-Efficacy and Attention of Individuals in the Treatment of Substance Use Disorders: A Feasibility Study

by Evlalia Touloudi, Mary Hassandra, Vasileios T. Stavrou, Fotis Panagiotounis, Evangelos Galanis, Marios Goudas and Yannis Theodorakis

Brain Sci. 2024, 14(7), 724; https://doi.org/10.3390/brainsci14070724 - 18 Jul 2024

Viewed by 1925

Abstract

Background: The role of exercise programs during substance use disorder (SUD) treatment is considered particularly supportive in fostering positive psychological and behavioral changes. The treatment of SUD is a challenging and demanding process. Therefore, it is crucial to discover innovative methods to enhance [...] Read more.

Background: The role of exercise programs during substance use disorder (SUD) treatment is considered particularly supportive in fostering positive psychological and behavioral changes. The treatment of SUD is a challenging and demanding process. Therefore, it is crucial to discover innovative methods to enhance and facilitate it. Integrating exercise into a virtual environment is an innovative approach for drug rehabilitation, offering multiple benefits to individuals undergoing treatment. The aim of this feasibility study was to explore the acute effects of cycling exercise in an immersive virtual reality (VR) environment on attentional control and self-efficacy expectations of individuals undergoing SUD treatment. Methods: A total of 20 individuals (mean age of 37.75 years) enrolled in a SUD treatment program participated in the study. They were instructed to complete a single session of cycling with a self-selected duration within the VR system. Results: Following the cycling session, pre-post measures indicated a statistically significant improvement in self-efficacy expectations and attentional control measured with the Stroop test. The results revealed that participants expressed high levels of intention for future use, interest/enjoyment, and positive attitudes toward the VR exercise system. Qualitative data indicated that participants found the VR exercise system enjoyable, expressed a strong intention to use it, and did not encounter technical difficulties or negative emotions. Conclusions: In conclusion, it seems that engaging in a brief period of self-selected exercise within a virtual environment can result in temporary activation of cognitive changes, heightened self-efficacy expectations, and a motivating approach to increasing physical activity participation among individuals with SUD, thus suggesting the feasibility of this approach. Full article

(This article belongs to the Topic New Advances in Addiction Behavior)

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12 pages, 259 KiB  

Open AccessEditor’s ChoicePerspective

Enhancing Substance Use Disorder Recovery through Integrated Physical Activity and Behavioral Interventions: A Comprehensive Approach to Treatment and Prevention

by Yannis Theodorakis, Mary Hassandra and Fotis Panagiotounis

Brain Sci. 2024, 14(6), 534; https://doi.org/10.3390/brainsci14060534 - 24 May 2024

Cited by 5 | Viewed by 8658

Abstract

The global issue of substance abuse demands ongoing initiatives aligned with the United Nations Sustainable Development Goals. With drug use remaining prevalent worldwide, interventions are critical to addressing the associated health challenges and societal implications. Exercise and physical activities have emerged as integral [...] Read more.

The global issue of substance abuse demands ongoing initiatives aligned with the United Nations Sustainable Development Goals. With drug use remaining prevalent worldwide, interventions are critical to addressing the associated health challenges and societal implications. Exercise and physical activities have emerged as integral components of substance use disorder (SUD) treatment, offering promising avenues for prevention, intervention, and recovery. Recent research underscores the efficacy of exercise in reducing substance cravings, promoting abstinence, and improving overall well-being. However, integrating exercise into SUD recovery programs presents challenges such as dropout rates and cultural considerations. This paper synthesizes existing literature on exercise integration into SUD recovery, highlighting strategies for enhancing treatment outcomes and addressing barriers to exercise adherence. Drawing on cognitive–behavioral therapy, experiential learning, motivational interviewing, and goal-setting techniques, the holistic approach outlined in this paper aims to empower individuals both mentally and physically, fostering resilience and supporting long-term recovery. In conclusion, new initiatives need to be taken by advocating for inclusive policies, promoting community engagement, and fostering collaborations across sectors. By doing so, stakeholders can optimize the effectiveness of exercise programs and contribute to sustainable rehabilitation efforts for individuals with SUD. Full article

(This article belongs to the Topic New Advances in Addiction Behavior)

23 pages, 1553 KiB  

Open AccessArticle

Betting on Your Feelings: The Interplay between Emotion and Cognition in Gambling Affective Task

by Emanuela Mari, Clarissa Cricenti, Maddalena Boccia, Micaela Maria Zucchelli, Raffaella Nori, Laura Piccardi, Anna Maria Giannini and Alessandro Quaglieri

J. Clin. Med. 2024, 13(10), 2990; https://doi.org/10.3390/jcm13102990 - 19 May 2024

Viewed by 2692

Abstract

Background: Gambling Disorder (GD) is a bio-psycho-social disorder resulting from the interaction of clinical, cognitive, and affective factors. Impulsivity is a crucial factor in addiction studies, as it is closely linked to cognitive distortions in GD by encompassing impulsive choices, motor responses, [...] Read more.

Background: Gambling Disorder (GD) is a bio-psycho-social disorder resulting from the interaction of clinical, cognitive, and affective factors. Impulsivity is a crucial factor in addiction studies, as it is closely linked to cognitive distortions in GD by encompassing impulsive choices, motor responses, decision-making, and cognitive biases. Also, emotions, mood, temperament, and affective state are crucial in developing and maintaining GD. Gambling can be used as a maladaptive coping strategy to avoid or escape problems and distress. Methods: The aim of the present study is to explore differences in personality traits and emotion regulation of people suffering from GD, substance-dependent gamblers (SDGs), and healthy controls (HCs). Additionally, the study proposes a new experimental task: the “Gambling Affective Task” (GAT) to investigate the influence of affective priming on risk-taking behaviors. Results: Our findings indicate that participants placed lower bets following positive priming. Additionally, SDGs wagered significantly higher amounts than HCs, regardless of priming type. In general, participants exhibited longer response times after positive priming trials, compared to negative and neutral priming trials. These findings suggest that experiencing positive emotions can act as a protective factor by delaying and lengthening gambling behaviors. By comparing gamblers with and without substance comorbidity, we can gain insight into the exclusive factors of GD and improve our understanding of this disorder. Conclusions: By elucidating the impact of emotional states on risk-taking, the research also provides new insights into the prevention and treatment of GD. Full article

(This article belongs to the Topic New Advances in Addiction Behavior)

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