Prodrugs
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (20 January 2011) | Viewed by 622941
Special Issue Editor
Interests: heterocycles; medicinal chemistry; green chemistry; microwave-induced synthesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Working in the field of medicinal chemistry is a daily challenge. One has to design novel structures, prepare substances, purify them (an often tedious task), and “finally”, the substances are screened. With luck, some promising candidates will emerge from one’s chemical libraries. Then one has to go back to the lab and try to improve the efficacy of one’s leads by introducing some subtle modifications in their skeleton. At that point, one may realizes that there is an excellent potential drug but, some of its physical or pharmacological properties will hinder its development. Hopefully, under such circumstances, one will be able to circumvent those problems by conceiving some prodrugs.
This Special Issue focuses on all kinds of efforts made in order to discover, characterize, and study substances that can be metabolized into active species. Bioconjugation, drug delivery methodologies, and other fields of research closely related to the prodrug approach will also be considered with great interest and pleasure.
Dr. Jean Jacques Vanden Eynde
Guest Editor
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Keywords
- prodrugs
- prodrug
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Related Special Issues
- Prodrugs in Pharmaceuticals (1 article)
- Prodrugs: from Design to Clinic in Pharmaceuticals (7 articles)