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Biology, Volume 11, Issue 3

2022 March - 137 articles

Cover Story: Atherosclerosis remains one of the leading causes of cardiovascular death worldwide, but predicting which atherosclerotic plaque becomes vulnerable and might rupture remains elusive. Non-invasive PET/CT imaging targeting novel pro-inflammatory markers could aid in the detection of these risky and potentially lethal plaques. CD40 is a co-stimulatory molecule expressed on multiple cell types within plaques, and its expression is associated with plaque vulnerability. Using PET imaging with Zirconium-89 labeled anti-CD40 monoclonal antibody (mAb) could shed light on the potential of immuno-PET as a modality for identifying vulnerable plaques in human. Therefore, Poels and Schreurs et al. evaluated the applicability of a [89Zr]Zr-anti-CD40 mAb to non-invasively detect vulnerable lesions in vivo in a mouse model of atherosclerosis. View this paper
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Articles (137)

  • Systematic Review
  • Open Access
48 Citations
9,781 Views
22 Pages

The Relationship between Physical Activity, Physical Exercise, and Human Gut Microbiota in Healthy and Unhealthy Subjects: A Systematic Review

  • Stefania Cataldi,
  • Valerio Bonavolontà,
  • Luca Poli,
  • Filipe Manuel Clemente,
  • Michele De Candia,
  • Roberto Carvutto,
  • Ana Filipa Silva,
  • Georgian Badicu,
  • Gianpiero Greco and
  • Francesco Fischetti

21 March 2022

Several studies have been conducted to find at least an association between physical activity (PA)/ physical exercise (PE) and the possibility to modulate the gut microbiome (GM). However, the specific effects produced on the human GM by different ty...

  • Article
  • Open Access
1 Citations
3,152 Views
10 Pages

An Alternative Class of Targets for microRNAs Containing CG Dinucleotide

  • Wennan Dai,
  • Xin Su,
  • Bin Zhang,
  • Kejing Wu,
  • Pengshan Zhao and
  • Zheng Yan

21 March 2022

MicroRNAs (miRNAs) are endogenous ~23 nt RNAs which regulate message RNA (mRNA) targets mainly through perfect pairing with their seed region (positions 2–7). Several instances of UTR sequence with an additional nucleotide that might form a bul...

  • Article
  • Open Access
8 Citations
3,407 Views
16 Pages

Bulked Segregant Analysis and Association Analysis Identified the Polymorphisms Related to the Intermuscular Bones in Common Carp (Cyprinus carpio)

  • Ming-Shu Cui,
  • Ran Zhao,
  • Qi Wang,
  • Yan Zhang,
  • Qing-Song Li,
  • Mei-Di Huang Yang,
  • Xiao-Qing Sun and
  • Jiong-Tang Li

21 March 2022

The allotetraploid common carp is one of the most important freshwater food fish. However, the IBs found in allotetraploid common carp increase the difficulty in fish meat processing and consumption. Although candidate genes associated with the total...

  • Article
  • Open Access
10 Citations
4,401 Views
14 Pages

Age Estimate of GJB2-p.(Arg143Trp) Founder Variant in Hearing Impairment in Ghana, Suggests Multiple Independent Origins across Populations

  • Elvis Twumasi Aboagye,
  • Samuel Mawuli Adadey,
  • Kevin Esoh,
  • Mario Jonas,
  • Carmen de Kock,
  • Lucas Amenga-Etego,
  • Gordon A. Awandare and
  • Ambroise Wonkam

21 March 2022

Gap junction protein beta 2 (GJB2) (connexin 26) variants are commonly implicated in non-syndromic hearing impairment (NSHI). In Ghana, the GJB2 variant p.(Arg143Trp) is the largest contributor to NSHI and has a reported prevalence of 25.9% in affect...

  • Article
  • Open Access
6 Citations
4,323 Views
15 Pages

19 March 2022

The spiny lobster Palinurus elephas has been intensively harvested across its range and is generally considered overfished, with global landings declining sharply from an average of 820 t in 1960–79 to 385 t in 2000–19. Despite its econom...

  • Article
  • Open Access
17 Citations
4,734 Views
18 Pages

Effects of Chronic High-Frequency rTMS Protocol on Respiratory Neuroplasticity Following C2 Spinal Cord Hemisection in Rats

  • Pauline Michel-Flutot,
  • Isley Jesus,
  • Valentin Vanhee,
  • Camille H. Bourcier,
  • Laila Emam,
  • Abderrahim Ouguerroudj,
  • Kun-Ze Lee,
  • Lyandysha V. Zholudeva,
  • Michael A. Lane and
  • Stéphane Vinit
  • + 2 authors

19 March 2022

High spinal cord injuries (SCIs) lead to permanent diaphragmatic paralysis. The search for therapeutics to induce functional motor recovery is essential. One promising noninvasive therapeutic tool that could harness plasticity in a spared descending...

  • Article
  • Open Access
4 Citations
3,934 Views
10 Pages

Physiological Response to Thermal Stress in Obese vs. Non-Obese Physically Inactive Men

  • Robert Podstawski,
  • Krzysztof Borysławski,
  • Andrzej Pomianowski,
  • Imre Soós,
  • Michał Boraczyński and
  • Piotr Gronek

18 March 2022

The effects of thermal stress on the physiological parameters of obese subjects remain insufficiently researched. The objective of this study was to determine the influence of sauna bathing on the physiological parameters of obese and non-obese physi...

  • Review
  • Open Access
17 Citations
5,659 Views
27 Pages

Significance of Shewanella Species for the Phytoavailability and Toxicity of Arsenic—A Review

  • Aminu Darma,
  • Jianjun Yang,
  • Peiman Zandi,
  • Jin Liu,
  • Katarzyna Możdżeń,
  • Xing Xia,
  • Ali Sani,
  • Yihao Wang and
  • Ewald Schnug

18 March 2022

The distribution of arsenic continues due to natural and anthropogenic activities, with varying degrees of impact on plants, animals, and the entire ecosystem. Interactions between iron (Fe) oxides, bacteria, and arsenic are significantly linked to c...

  • Article
  • Open Access
5 Citations
5,307 Views
17 Pages

18 March 2022

A mild to moderate increase in acute-phase proteins (APPs) and a decrease in serum albumin levels are detected in hospitalized COVID-19 patients. A similar trend is also observed for acute-phase cytokines (APC), mainly IL6, besides chemokines (e.g.,...

  • Review
  • Open Access
89 Citations
15,751 Views
45 Pages

A Comprehensive Survey on the Detection, Classification, and Challenges of Neurological Disorders

  • Aklima Akter Lima,
  • M. Firoz Mridha,
  • Sujoy Chandra Das,
  • Muhammad Mohsin Kabir,
  • Md. Rashedul Islam and
  • Yutaka Watanobe

18 March 2022

Neurological disorders (NDs) are becoming more common, posing a concern to pregnant women, parents, healthy infants, and children. Neurological disorders arise in a wide variety of forms, each with its own set of origins, complications, and results....

  • Article
  • Open Access
21 Citations
3,380 Views
13 Pages

Radiomics Metrics Combined with Clinical Data in the Surgical Management of Early-Stage (cT1–T2 N0) Tongue Squamous Cell Carcinomas: A Preliminary Study

  • Umberto Committeri,
  • Roberta Fusco,
  • Elio Di Bernardo,
  • Vincenzo Abbate,
  • Giovanni Salzano,
  • Fabio Maglitto,
  • Giovanni Dell’Aversana Orabona,
  • Pasquale Piombino,
  • Paola Bonavolontà and
  • Luigi Califano
  • + 8 authors

18 March 2022

Objective: To predict the risk of metastatic lymph nodes and the tumor grading related to oral tongue squamous cell carcinoma (OTSCC) through the combination of clinical data with radiomics metrics by computed tomography, and to develop a supportive...

  • Article
  • Open Access
25 Citations
3,707 Views
14 Pages

18 March 2022

The purpose of this study was two-fold: (a) to describe and analyse the relationship of the in-season variations of external and internal intensity metrics as well as well-being measures across different periods of a semi-professional soccer season (...

  • Article
  • Open Access
5 Citations
3,065 Views
16 Pages

18 March 2022

The allo-tetraploid common carp, one widely cultured food fish, is able to produce poly-unsaturated fatty acids (PUFAs). The genetic markers on the PUFA contents for breeding was limited. The polymorphisms in elovl5a and elovl5b, the rate-limiting en...

  • Article
  • Open Access
2 Citations
3,766 Views
13 Pages

18 March 2022

Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), an infectious disease that spreads rapidly in humans. In March 2020, the World Health Organization (WHO) declared a COVID-19 pandemic. Identifyin...

  • Article
  • Open Access
11 Citations
3,416 Views
12 Pages

17 March 2022

Assassin bugs use their salivary venoms for various purposes, including defense, prey paralyzation, and extra-oral digestion, but the mechanisms underlying the functional complexity of the venom remain largely unclear. Since venom glands are composed...

  • Article
  • Open Access
6 Citations
3,387 Views
20 Pages

Selenium Nanoparticles Biosynthesized by Pantoea agglomerans and Their Effects on Cellular and Physiological Parameters in the Rainbow Trout Oncorhynchus mykiss

  • Francisco Yanez-Lemus,
  • Rubén Moraga,
  • Luis Mercado,
  • Carlos Jara-Gutierrez,
  • Carlos T. Smith,
  • Paulina Aguayo,
  • Kimberly Sanchez-Alonzo,
  • Apolinaria García-Cancino,
  • Ariel Valenzuela and
  • Victor L. Campos

17 March 2022

The applications of nanoparticles (Nps) as food additives, health enhancers, and antimicrobials in animal production are increasing. The aim of this study was to evaluate the effect of selenium (Se) nanoparticles (Se0Nps) stabilized with L-cysteine (...

  • Article
  • Open Access
17 Citations
4,026 Views
23 Pages

DNA Barcoding, GIS-Facilitated Seed Germination and Pilot Cultivation of Teucrium luteum subsp. gabesianum (Lamiaceae), a Tunisian Local Endemic with Potential Medicinal and Ornamental Value

  • Stefanos Kostas,
  • Stefanos Hatzilazarou,
  • Elias Pipinis,
  • Soumaya Bourgou,
  • Imtinen Ben Haj Jilani,
  • Wafa Ben Othman,
  • Wided Megdiche-Ksouri,
  • Zeineb Ghrabi-Gammar,
  • Mohamed Libiad and
  • Nikos Krigas
  • + 9 authors

17 March 2022

In the context of plant conservation and sustainable use of unique neglected and underutilized phytogenetic resources, this study focused on the Tunisian local endemic Teucrium luteum subsp. gabesianum (Lamiaceae). Using Geographical Information Syst...

  • Article
  • Open Access
10 Citations
5,332 Views
15 Pages

Spatial Metagenomic Analysis in Understanding the Microbial Diversity of Thar Desert

  • Jagdish Parihar,
  • Suraj P. Parihar,
  • Prashanth Suravajhala and
  • Ashima Bagaria

17 March 2022

The arid and semi-arid regions of Rajasthan are one of the most extreme biomes of India, possessing diverse microbial communities that exhibit immense biotechnological potential for industries. Herein, we sampled study sites from arid and semi-arid r...

  • Review
  • Open Access
5 Citations
11,646 Views
13 Pages

17 March 2022

Deep penetrating nevus (DPN) is an uncommon acquired melanocytic lesion with a distinct histopathological appearance that typically behaves in an indolent manner. The lesion is characterized by a symmetrical proliferation of epithelioid to spindled m...

  • Article
  • Open Access
4 Citations
6,342 Views
18 Pages

Deep Insights into the Specific Evolution of Fungal Hybrid B Heme Peroxidases

  • Marcel Zámocký,
  • Miloš Musil,
  • Maksym Danchenko,
  • Peter Ferianc,
  • Katarína Chovanová,
  • Peter Baráth,
  • Andrej Poljovka and
  • David Bednář

17 March 2022

In this study, we focus on a detailed bioinformatics analysis of hyBpox genes, mainly within the genomes of Sclerotiniaceae (Ascomycota, Leotiomycetes), which is a specifically evolved fungal family of necrotrophic host generalists and saprophytic or...

  • Review
  • Open Access
7 Citations
7,121 Views
21 Pages

Seaweed’s Role in Energetic Transition—From Environmental Pollution Challenges to Enhanced Electrochemical Devices

  • Susete Pinteus,
  • Patrícia Susano,
  • Celso Alves,
  • Joana Silva,
  • Alice Martins and
  • Rui Pedrosa

17 March 2022

Resulting from the growing human population and the long dependency on fossil-based energies, the planet is facing a critical rise in global temperature, which is affecting all ecosystem networks. With a growing consciousness this issue, the EU has d...

  • Article
  • Open Access
3 Citations
2,920 Views
12 Pages

Influence of Apnea Hypopnea Index and the Degree of Airflow Limitation on Endothelial Function in Patients Undergoing Diagnostic Coronary Angiography

  • Dorota Ochijewicz,
  • Adam Rdzanek,
  • Tadeusz Przybyłowski,
  • Renata Rubinsztajn,
  • Monika Budnik,
  • Ewa Pędzich,
  • Katarzyna Białek-Gosk,
  • Piotr Bielicki and
  • Agnieszka Kapłon-Cieślicka

17 March 2022

Background: Obstructive sleep apnea is associated with an increased prevalence of cardiovascular disease. The mechanism of these associations is not completely understood. We aimed to investigate the association of the apnea hypopnea index and the de...

  • Article
  • Open Access
9 Citations
3,624 Views
15 Pages

Identification and Characterization of MicroRNAs Involving in Initial Sex Differentiation of Chlamys farreri Gonads

  • Xixi Li,
  • Siyu Lin,
  • Shutong Fan,
  • Xiaoting Huang,
  • Zhifeng Zhang and
  • Zhenkui Qin

16 March 2022

Research on expressional regulation of genes at the initial sex differentiation of gonads will help to elucidate the mechanisms of sex determination and differentiation in animals. However, information on initial sex differentiation of gonads is limi...

  • Article
  • Open Access
47 Citations
7,275 Views
20 Pages

Traditions for Future Cross-National Food Security—Food and Foraging Practices among Different Native Communities in the Western Himalayas

  • Shiekh Marifatul Haq,
  • Musheerul Hassan,
  • Hammad Ahmad Jan,
  • Abdullah Ahmed Al-Ghamdi,
  • Khalid Ahmad and
  • Arshad Mehmood Abbasi

16 March 2022

Traditional diets exist in all cultures and geographic regions, and they often represent healthy eating options. Traditional culinary preparations have, however, often undergone profound change, even in the isolated Himalayan region. Therefore, we ad...

  • Review
  • Open Access
12 Citations
9,597 Views
27 Pages

Advanced Diffusion MRI of the Visual System in Glaucoma: From Experimental Animal Models to Humans

  • Monica Mendoza,
  • Max Shotbolt,
  • Muneeb A. Faiq,
  • Carlos Parra and
  • Kevin C. Chan

16 March 2022

Glaucoma is a group of ophthalmologic conditions characterized by progressive retinal ganglion cell death, optic nerve degeneration, and irreversible vision loss. While intraocular pressure is the only clinically modifiable risk factor, glaucoma may...

  • Article
  • Open Access
9 Citations
3,422 Views
17 Pages

Molecular Characterization and Expression Pattern of Paramyosin in Larvae and Adults of Yesso Scallop

  • Yumin Yang,
  • Dan Zhao,
  • Liqing Zhou,
  • Tianshi Zhang,
  • Zhihong Liu,
  • Biao Wu,
  • Tao Yu,
  • Yanxin Zheng and
  • Xiujun Sun

16 March 2022

Paramyosin is an important myofibrillar protein in molluscan smooth muscle. The full-length cDNA encoding paramyosin has been identified from Yesso scallop Patinopecten yessoensis. The length of paramyosin molecule has been found to be 3715 bp, which...

  • Article
  • Open Access
13 Citations
3,024 Views
13 Pages

The Utility of ADC First-Order Histogram Features for the Prediction of Metachronous Metastases in Rectal Cancer: A Preliminary Study

  • Bianca Boca (Petresc),
  • Cosmin Caraiani,
  • Loredana Popa,
  • Andrei Lebovici,
  • Diana Sorina Feier,
  • Carmen Bodale and
  • Mircea Marian Buruian

16 March 2022

This study aims the ability of first-order histogram-based features, derived from ADC maps, to predict the occurrence of metachronous metastases (MM) in rectal cancer. A total of 52 patients with pathologically confirmed rectal adenocarcinoma were re...

  • Article
  • Open Access
15 Citations
4,617 Views
13 Pages

Impact of Red Complex Bacteria and TNF-α Levels on the Diabetic and Renal Status of Chronic Kidney Disease Patients in the Presence and Absence of Periodontitis

  • Jaideep Mahendra,
  • Plato Palathingal,
  • Little Mahendra,
  • Khalid J. Alzahrani,
  • Hamsa Jameel Banjer,
  • Khalaf F. Alsharif,
  • Ibrahim Faisal Halawani,
  • Janani Muralidharan,
  • Pandapulaykal T. Annamalai and
  • Shankargouda Patil
  • + 4 authors

16 March 2022

Scientific evidence shows a positive association in the etiopathogenesis of periodontitis and chronic kidney disease (CKD). Various confounding factors, such as obesity, diabetes, and inflammation, also play a significant role in the progression of C...

  • Article
  • Open Access
29 Citations
4,754 Views
20 Pages

16 March 2022

The present study aimed to investigate the effect of the royal jelly (RJ) on hepatotoxicity induced by molybdenum nanoparticles (MoO3-NPs), cadmium chloride (CdCl2), or their combination in male rats at biochemical, inflammation, immune response, his...

  • Article
  • Open Access
8 Citations
4,520 Views
20 Pages

16 March 2022

Background: Caloric restriction (CR) extends lifespan in many species, including mammals. CR is cardioprotective in senescent myocardium by correcting pre-existing mitochondrial dysfunction and apoptotic activation. Furthermore, it confers cardioprot...

  • Article
  • Open Access
5 Citations
3,431 Views
18 Pages

Post-Irradiation Thymic Regeneration in B6C3F1 Mice Is Age Dependent and Modulated by Activation of the PI3K-AKT-mTOR Pathway

  • Masaaki Sunaoshi,
  • Benjamin J. Blyth,
  • Yi Shang,
  • Chizuru Tsuruoka,
  • Takamitsu Morioka,
  • Mayumi Shinagawa,
  • Mari Ogawa,
  • Yoshiya Shimada,
  • Akira Tachibana and
  • Shizuko Kakinuma
  • + 1 author

16 March 2022

The risk of radiation-induced carcinogenesis depends on age at exposure. We previously reported principal causative genes in lymphomas arising after infant or adult exposure to 4-fractionated irradiation as Pten or Ikzf1, respectively, suggesting tha...

  • Article
  • Open Access
1 Citations
2,611 Views
17 Pages

Rs868058 in the Homeobox Gene HLX Contributes to Early-Onset Fetal Growth Restriction

  • Wioletta Izabela Wujcicka,
  • Marian Kacerovsky,
  • Michał Krekora,
  • Piotr Kaczmarek,
  • Beata Leśniczak and
  • Mariusz Grzesiak

16 March 2022

Fetal growth restriction (FGR) is a condition that characterizes fetuses as too small for their gestational age, with an estimated fetal weight (EFW) below the 10th percentile and abnormal Doppler parameters and/or with EFW below the 3rd percentile....

  • Article
  • Open Access
7 Citations
3,137 Views
17 Pages

Transcription Regulation of Tceal7 by the Triple Complex of Mef2c, Creb1 and Myod

  • Zhenzhen Xiong,
  • Mengni Wang,
  • Shanshan You,
  • Xiaoyan Chen,
  • Jiangguo Lin,
  • Jianhua Wu and
  • Xiaozhong Shi

16 March 2022

Tceal7 has been identified as a direct, downstream target gene of MRF in the skeletal muscle. The overexpression of Tceal7 represses myogenic proliferation and promotes cell differentiation. Previous studies have defined the 0.7 kb upstream fragment...

  • Article
  • Open Access
11 Citations
4,530 Views
19 Pages

Investigation of the JASMONATE ZIM-DOMAIN Gene Family Reveals the Canonical JA-Signaling Pathway in Pineapple

  • Li Ye,
  • Ling Cao,
  • Xuemei Zhao,
  • Xinya Guo,
  • Kangzhuo Ye,
  • Sibo Jiao,
  • Yu Wang,
  • Xiaoxue He,
  • Chunxing Dong and
  • Yan Cheng
  • + 6 authors

15 March 2022

JASMONATE ZIM-DOMAIN (JAZ) proteins are negative regulators of the jasmonate (JA)-signaling pathway and play pivotal roles in plant resistance to biotic and abiotic stresses. Genome-wide identification of JAZ genes has been performed in many plant sp...

  • Article
  • Open Access
51 Citations
4,753 Views
10 Pages

Atrial High-Rate Episodes Detected by Cardiac Implantable Electronic Devices: Dynamic Changes in Episodes and Predictors of Incident Atrial Fibrillation

  • Jacopo Francesco Imberti,
  • Niccolò Bonini,
  • Alberto Tosetti,
  • Davide Antonio Mei,
  • Luigi Gerra,
  • Vincenzo Livio Malavasi,
  • Andrea Mazza,
  • Gregory Y. H. Lip and
  • Giuseppe Boriani

15 March 2022

Background. Atrial high rate episodes (AHRE) detected by cardiac implantable electronic devices (CIEDs) may be associated with a risk of progression towards long-lasting episodes (≥24 h) and clinical atrial fibrillation (AF). Methods. Consecutive...

  • Article
  • Open Access
12 Citations
5,148 Views
20 Pages

ATP Purinergic Receptor P2X1-Dependent Suicidal NETosis Induced by Cryptosporidium parvum under Physioxia Conditions

  • Seyed Sajjad Hasheminasab,
  • Iván Conejeros,
  • Zahady D. Velásquez,
  • Tilman Borggrefe,
  • Ulrich Gärtner,
  • Faustin Kamena,
  • Anja Taubert and
  • Carlos Hermosilla

14 March 2022

Cryptosporidiosis is a zoonotic intestinal disease that affects humans, wildlife, and neonatal cattle, caused by Cryptosporidium parvum. Neutrophil extracellular traps (NETs), also known as suicidal NETosis, are a powerful and ancient innate effector...

  • Review
  • Open Access
34 Citations
6,373 Views
23 Pages

UGT72, a Major Glycosyltransferase Family for Flavonoid and Monolignol Homeostasis in Plants

  • Nathanaël Speeckaert,
  • Mondher El Jaziri,
  • Marie Baucher and
  • Marc Behr

14 March 2022

Plants have developed the capacity to produce a diversified range of specialized metabolites. The glycosylation of those metabolites potentially decreases their toxicity while increasing their stability and their solubility, modifying their transport...

  • Review
  • Open Access
34 Citations
6,013 Views
34 Pages

Endocannabinoid Modulation in Neurodegenerative Diseases: In Pursuit of Certainty

  • Alexandru Vasincu,
  • Răzvan-Nicolae Rusu,
  • Daniela-Carmen Ababei,
  • Mădălina Larion,
  • Walther Bild,
  • Gabriela Dumitrița Stanciu,
  • Carmen Solcan and
  • Veronica Bild

14 March 2022

Neurodegenerative diseases are an increasing cause of global morbidity and mortality. They occur in the central nervous system (CNS) and lead to functional and mental impairment due to loss of neurons. Recent evidence highlights the link between neur...

  • Article
  • Open Access
145 Citations
8,472 Views
17 Pages

14 March 2022

Clinical Decision Support Systems (CDSS) provide an efficient way to diagnose the presence of diseases such as breast cancer using ultrasound images (USIs). Globally, breast cancer is one of the major causes of increased mortality rates among women....

  • Article
  • Open Access
1 Citations
3,928 Views
12 Pages

13 March 2022

Sound production in the blackmouth croaker (Atrobucca nibe) was characterized using acoustic, morphological, and histochemical methods. Their calls consisted of a train of two to seven pulses; the frequency ranged from 180 to 3000 Hz, with a dominant...

  • Review
  • Open Access
154 Citations
11,653 Views
26 Pages

12 March 2022

The recent literature indicates that plant growth-promoting bacteria (PGPB) employ a range of mechanisms to augment a plant’s ability to ameliorate salt and drought stress. These mechanisms include synthesis of auxins, especially indoleacetic a...

  • Article
  • Open Access
24 Citations
6,293 Views
19 Pages

Effects of Temperature and Salinity on Growth, Metabolism and Digestive Enzymes Synthesis of Goniopora columna

  • De-Sing Ding,
  • Anil Kumar Patel,
  • Reeta Rani Singhania,
  • Chiu-Wen Chen and
  • Cheng-Di Dong

11 March 2022

Climate change is causing dramatic changes in global ocean temperature and salinity, threatening coral survival. Coral growth and metabolism are greatly affected by the temperature, salinity and feeding time of the environment. In order to explore th...

  • Brief Report
  • Open Access
2 Citations
2,869 Views
9 Pages

Heterozygosity of the Complex Corfu δ0β+ Thalassemic Allele (HBD Deletion and HBB:c.92+5G>A) Revisited

  • Christos Kattamis,
  • Myrto Skafida,
  • Polyxeni Delaporta,
  • Christina Vrettou,
  • Joanne Traeger-Synodinos,
  • Christalena Sofocleous and
  • Antonis Kattamis

11 March 2022

The Corfu δ0β+ thalassemic allele is a unique thalassemic allele consisting of the simultaneous presence in cis of a deletion of the δ-globin (Hemoglobin Subunit Delta, HBD) and a single nucleotide variant in the β-globin gene (...

  • Article
  • Open Access
2 Citations
7,170 Views
14 Pages

Long-Term Outcomes of Dose-Escalated Hypofractionated Radiotherapy in Localized Prostate Cancer

  • Antonio Lazo,
  • Alejandro de la Torre-Luque,
  • Gregorio Arregui,
  • Daniel Rivas,
  • Ana Serradilla,
  • Joaquin Gómez,
  • Francisca Jurado,
  • María Isabel Núñez and
  • Escarlata López

11 March 2022

This retrospective study aimed to provide some clinical outcomes regarding effectiveness, toxicity, and quality of life in PCa patients treated with dose-escalated moderately hypofractionated radiation therapy (HFRT). Patients received HFRT to a tota...

  • Article
  • Open Access
7 Citations
3,840 Views
15 Pages

Selected vs. Non-Selected Under-20 National Futsal Players: Differences between Physical Performance and Training Intensity Experienced in Training Camps

  • Ana Filipa Silva,
  • Francisco Tomás González-Fernández,
  • Rafael Oliveira,
  • Filipe Manuel Clemente,
  • Pedro Bezerra,
  • Chin-Hwai Hung,
  • Yi-Wen Chiu,
  • Cheng-Deng Kuo and
  • Yung-Sheng Chen

11 March 2022

The aim of this study was two-fold: (i) analyze the variations in the physical fitness of selected and non-selected under-20 male national futsal players; and (ii) analyze the variations in training intensity monitored during training camps. Thirty-t...

  • Article
  • Open Access
14 Citations
5,499 Views
33 Pages

Control of Cholesterol Metabolism Using a Systems Approach

  • Dorota Formanowicz,
  • Marcin Radom,
  • Agnieszka Rybarczyk,
  • Krzysztof Tanaś and
  • Piotr Formanowicz

11 March 2022

Cholesterol is an essential component of mammalian cells and is involved in many fundamental physiological processes; hence, its homeostasis in the body is tightly controlled, and any disturbance has serious consequences. Disruption of the cellular m...

  • Article
  • Open Access
9 Citations
5,838 Views
8 Pages

Pathobiology of Second-Generation Antihistamines Related to Sleep in Urticaria Patients

  • Caroline Mann,
  • Joanna Wegner,
  • Hans-Günter Weeß and
  • Petra Staubach

11 March 2022

Background: Standard treatment options for urticaria are second-generation antihistamines; however, their effect on sleep is uncertain. This study measures the influence of different antihistamines on the biologic sleep pattern of urticaria patients...

  • Article
  • Open Access
12 Citations
3,537 Views
17 Pages

The VIP/VPAC1R Pathway Regulates Energy and Glucose Homeostasis by Modulating GLP-1, Glucagon, Leptin and PYY Levels in Mice

  • Daniel Sanford,
  • Leon Luong,
  • John P. Vu,
  • Suwan Oh,
  • Arielle Gabalski,
  • Michael Lewis,
  • Joseph R. Pisegna and
  • Patrizia Germano

11 March 2022

Vasoactive Intestinal Peptide binds with high affinity to VPAC1R and VPAC2R, thus regulating key physiologic functions. Previously, we documented in VIP−/− mice a leaner body phenotype and altered metabolic hormones. Past reports describe...

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Biology - ISSN 2079-7737