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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Oxidative Stress Induced by Micro(Nano)plastics

edited by

Lavinia Casati

Alessandro Villa

and

Marco Parolini

submission deadline 30 Jun 2026 | 3 articles | Viewed by 12274 | Submission Open

Keywords: micro(nano)plastics; oxidative stress; One Health; in vitro and in vivo models; organisms; cellular microenvironment

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants from Plant-Based By-Products: Mechanisms and Applications in Food Systems

edited by

María Jesús Petrón Testón

submission deadline 30 Jun 2026 | 7 articles | Viewed by 11146 | Submission Open

Keywords: natural antioxidants; plant-based by-products; phenolic compounds; food preservation; shelf life extension; sustainable food systems; extraction techniques

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Chronic Pain and Oxidative Stress

edited by

Olga Pol

submission deadline 30 Jun 2026 | 5 articles | Viewed by 11084 | Submission Open

Keywords: analgesia; antioxidants; chemotherapy; heme oxygenase 1; neuropathy; nociception; Nrf2 transcription factor; oxidative stress; pain

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Harnessing Redox Status and Novel Molecular Signals and Targets Involved in Oxidative Stress to Afford Cardioprotection: From Experimental Insights to Clinical Applications

edited by

Tommaso Angelone

Carmine Rocca

and Anna De Bartolo

submission deadline 30 Jun 2026 | 4 articles | Viewed by 10661 | Submission Open

Keywords: oxidative stress; redox signaling; cardioprotection; antioxidants; heart disease; vascular dysfunction; molecular targets; therapeutic approaches

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Heme Oxygenase in Health and Disease: New Insights and Future Directions

edited by

J. Catharina Duvigneau

submission deadline 30 Jun 2026 | 4 articles | Viewed by 9427 | Submission Open

Keywords: enzyme activity; ferroptosis; carbon monoxide; oxidative stress; reactive oxygen and nitrogen species; heme proteins; heme degradation; heme responsive elements; heme regulation

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Editorial Board Members’ Collection Series: Advances in Redox-Tools and Therapies in Cardiovascular Disease

edited by

Andreas Daiber

Albino Carrizzo

and

Moo-Yeol Lee

submission deadline 30 Jun 2026 | 4 articles | Viewed by 9172 | Submission Open

Keywords: cardiovascular disease; oxidative stress; inflammation; reactive oxygen species; redox signalling

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Lipid Peroxidation and Cancer

edited by

Stefania Pizzimenti

and

Giuliana Muzio

submission deadline 30 Jun 2026 | 4 articles | Viewed by 6174 | Submission Open

Keywords: lipid peroxidation; fatty acid metabolism; 4-hydroxynonenal (HNE); malondialdehyde (MDA); ferroptosis; carcinogenesis; cancer progression

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Recent Advances in Applications of Nanoantioxidants

edited by

Anna Calarco

and

Raffaele Conte

submission deadline 30 Jun 2026 | 1 articles | Viewed by 4418 | Submission Open

Keywords: nanoantioxidants; nanoscale engineering; medicine; cosmetics; functional foods; material characterization

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidants for Skin Health—2nd Edition

edited by Rubia Casagrande

submission deadline 30 Jun 2026 | 1 articles | Viewed by 4352 | Submission Open

Keywords: skin inflammation; cytokine; skin oxidative stress; Nrf2; reduced glutathione; ultraviolet irradiation; drug delivery; flavonoid; terpenes; specialized pro-resolution lipid mediators

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Compounds: Antioxidant, Antibacterial, and Anti-Inflammatory Modulation—2nd Edition

edited by

Raquel Bridi

and

Christian Espinosa-Bustos

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2361 | Submission Open

Keywords: bioactive compounds; antioxidants; anti-inflammatory activity; antibacterial properties; reactive oxygen species; oxidative stress; phytochemicals

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Sustainable Food, Green Chemistry and Human Nutrition (GreenNutriFood 2025)

edited by

Mladen Brnčić

Antonela Ninčević Grassino

Jianjun Zhou

and Andrea Asensio-Grau

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1618 | Submission Open

Keywords: food; nutrition; food processing; food packaging; green chemistry; meat; food waste; by-products; functional foods; fermentation; biofortification; food additives; food safety; shelf life; gut microbiome; seafood; marine resources

Sustainable Strategies for Natural Antioxidant Utilization

edited by

Vlasios Goulas

and Atalanti Christou

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1287 | Submission Open

Keywords: extraction; antioxidants; polyphenols; phytochemicals; green chemistry; sustainable process; natural products; drug discovery; formulation; natural product analysis

Antioxidant and Anticancer Activities of Food Ingredients and Natural Products

edited by

Constantinos Giaginis

and

Efthymios Poulios

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1105 | Submission Open

Keywords: oxidative stress; cancer; disease prevention or therapy; oxidative biomarkers; quality of life; apoptosis; cell cycle arrest; antioxidant enzymes; reactive oxygen species

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Artificial Intelligence and Other Bioinformatic Modern Technologies Approaches to the Study of Antioxidant Capacity in Food Production

edited by

Giuseppe Perretti

submission deadline 30 Jun 2026 | Viewed by 802 | Submission Open

Keywords: artificial intelligence; bioinformatics; food processing; food quality; antioxidant capacity; big data

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Statins as Antioxidants: Beyond Their Cholesterol Lowering Activity

edited by

Arianna Vignini

and Sonila Alia

submission deadline 30 Jun 2026 | Viewed by 570 | Submission Open

Keywords: statins; cholesterol; HMGCoA reductase; antioxidant; anti-inflammatory; dysmetabolic diseases

Reactive Oxygen Species and Growth Factors in Photodynamic Therapy (PDT), Photobiomodulation (PBM), and Radiation Therapy (RT)—2nd Edition

edited by Timothy C. Zhu and Brian C. Wilson

submission deadline 30 Jun 2026 | 1 articles | Viewed by 522 | Submission Open

Keywords: reactive oxygen species (ROS); singlet oxygen (SO); radiation; photodynamic therapy; cancers

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Metabolism and Mitochondrial Dysfunction in Metabolic Diseases—3rd Edition

edited by

Gina Cavaliere

and

Giovanna Trinchese

submission deadline 30 Jun 2026 | Viewed by 508 | Submission Open

Keywords: mitochondria function; oxidative processes; metabolic diseases; reactive oxygen species; therapeutic approaches; mitochondrial integrity; energy production; mitochondrial bioenergetic; metabolism; mitochondrial dynamic

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Meat and Meat Products

edited by

Rubén Domínguez-Valencia

and

Mirian Pateiro

submission deadline 30 Jun 2026 | Viewed by 485 | Submission Open

Keywords: natural antioxidants; oxidative degradation; meat shelf-life; food quality; functional food; bioactive compounds; antioxidant active packaging

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Advances in Mitochondrial Redox Biology—Second Edition

edited by

Masuko Ushio-Fukai

submission deadline 30 Jun 2026 | Viewed by 457 | Submission Open

Keywords: mitochondria; redox signaling; reactive oxygen species (ROS); mitochondrial dynamics; bioenergetics; mitochondria– nuclear communication; aging; cell metabolism

Oxidative Stress in Neurodevelopmental Disorders

edited by

Marco Fiore

submission deadline 30 Jun 2026 | Viewed by 304 | Submission Open

Keywords: brain development; neurodevelopmental disorders; reactive oxygen species; attention deficit/hyperactivity disorder; fetal alcohol spectrum disorders; autism spectrum disorder; intellectual disability; neuroinflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Oxidative Stress in Chronic Pain and Inflammation

edited by

Lucia Carmela Passacatini

and

Saverio Nucera

submission deadline 30 Jun 2026 | Viewed by 247 | Submission Open

Keywords: chronic pain; oxidative stress; antioxidant; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Dialysis-Induced Oxidative Stress, MicroRNAs and Organ Damage: From Bench to Bedside

edited by

Yuri Battaglia

submission deadline 30 Jun 2026 | Viewed by 228 | Submission Open

Keywords: dialysis; hemodialysis; hemodiafiltration; oxidative stress; microRNAs; non-coding RNAs; organ damage; cardiovascular disease; inflammation; biomarkers; end-stage kidney disease; redox imbalance

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Chronic and End-Stage Kidney Disease: Defining Biological and Clinical Plausibility

edited by

Stefanos Roumeliotis

and

Vassilios Liakopoulos

submission deadline 30 Jun 2026 | Viewed by 196 | Submission Open

Keywords: CKD; ESKD; cardiovascular disease; catalase; chronic kidney disease; end stage kidney disease; N-acetylcysteine; superoxide dismutase; vascular calcification; vitamin C; vitamin E

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Agri-Food Wastes as Natural Source of Bioactive Antioxidants: Fourth Edition

edited by

Silvana Hrelia

Cristina Angeloni

and

Maria Cristina Barbalace

submission deadline 10 Jul 2026 | 10 articles | Viewed by 19264 | Submission Open

Keywords: agri-food by-products; agri-food waste; nutraceuticals; functional foods; cosmeceutical products; sustainable practices; bioactive compounds; health effects

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Heme Proteins and Signaling in Redox Biology

edited by

Brandon Reeder

submission deadline 10 Jul 2026 | 1 articles | Viewed by 1144 | Submission Open

Keywords: heme proteins; redox biology; globin; oxygen binding and sensing proteins

(This special issue belongs to the Section ROS, RNS and RSS)

Hydrophilic and Lipophilic Antioxidants in Foods and Food Processing

edited by

Volker Böhm

submission deadline 15 Jul 2026 | 2 articles | Viewed by 2478 | Submission Open

Keywords: antioxidant activity; antioxidant capacity; antioxidant mechanisms; carotenoids; polyphenols; vitamin C; vitamin E; impact of food processing

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Phytochemical Analysis and Evaluation of Antioxidant Properties in Medicinal Plants

edited by

Magdalena Jeszka-Skowron

Agnieszka Zgoła-Grześkowiak

Tomasz Grześkowiak

and

Robert Frankowski

submission deadline 20 Jul 2026 | 8 articles | Viewed by 29265 | Submission Open

Keywords: antioxidant activity; phytochemicals in plants; medicinal plants; extraction; in vivo analysis; in vitro analysis

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

The Interaction Between Gut Microbiota and Host Oxidative Stress

edited by

Jie Yin

submission deadline 20 Jul 2026 | 3 articles | Viewed by 11660 | Submission Open

Keywords: oxidative stress; antioxidants; gut microbiome; immunity

Glutathione and Health: From Development to Disease

edited by

Ying Chen

and Vasilis K. Vasiliou

submission deadline 20 Jul 2026 | 3 articles | Viewed by 8312 | Submission Open

Keywords: glutathione; antioxidants; antioxidant enzymes; oxidative stress; redox biology; molecular biology; cellular biology; biochemistry; development; disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Multifunction Photoprotection—2nd Edition

edited by

André Rolim Baby

and

Catarina Rosado

submission deadline 20 Jul 2026 | 1 articles | Viewed by 8251 | Submission Open

Keywords: natural and synthetic antioxidants; sunscreens; multifunctional products; safety and efficacy establishment; product technologies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress Induced by Air Pollution, 3rd Edition

edited by

Yasuhiro Yoshida

submission deadline 20 Jul 2026 | 3 articles | Viewed by 3002 | Submission Open

Keywords: particulate matter; air pollution; oxidative stress; reactive oxygen species; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Lipid Peroxidation, Vegetable Oil Oxidation, and the Role of Plant Extracts in Enhancing Oxidative Stability

edited by

Daniele Sanna

and

Angela Fadda

submission deadline 20 Jul 2026 | 2 articles | Viewed by 1703 | Submission Open

Keywords: oil oxidative stability; natural antioxidants; lipid peroxidation; surfactants; encapsulation

(This special issue belongs to the Section Aberrant Oxidation of Biomolecules)

Applications and Health Benefits of Novel Antioxidant Biomaterials—2nd Edition

edited by

Washington Luiz Esteves Magalhães

and Tielidy Lima

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1404 | Submission Open

Keywords: antioxidant biomaterials; tissue regeneration; biocompatibility; controlled release; premature aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Regulation in Algae

edited by

Kim Gwang Hoon

submission deadline 20 Jul 2026 | Viewed by 283 | Submission Open

Keywords: algae; reactive oxygen species; redox regulation; stress responses; NADPH oxidases; antioxidants; redox-sensitive transcription factors

(This special issue belongs to the Section ROS, RNS and RSS)

The Role of Oxidative Stress in Age-Related and Degenerative Eye Diseases

edited by

Ting Zhang

submission deadline 30 Jul 2026 | 5 articles | Viewed by 6648 | Submission Open

Keywords: oxidative stress; age-related macular degeneration; retinal degeneration; reactive oxygen species; redox signaling; mitochondrial dysfunction; antioxidant therapy; artificial intelligence; multi-omics; biomarkers; vision science

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Selected Papers from the 2nd International Electronic Conference on Antioxidants (IECAN2025)

edited by

Alessandra Napolitano

and

Mario Allegra

submission deadline 31 Jul 2026 | 4 articles | Viewed by 21568 | Submission Open

Keywords: obesity; cardiovascular diseases; chronic disease; dietary prevention; antioxidants intake; gut microbiome; natural and synthetic antioxidants; antioxidant enzyme systems; antioxidant extraction

Green Extraction of Antioxidant from Natural Source

edited by

Jolanta Flieger

submission deadline 31 Jul 2026 | 8 articles | Viewed by 18620 | Submission Open

Keywords: green extraction techniques ; supercritical fluid extraction ; ionic liquid (IL)-based extraction; microwave-assisted extraction; antioxidants; plants; cosmetic formulation

Antioxidants as Adjuvants for Inflammatory Bowel Disease Treatment

edited by

Marcello Chieppa

and

Angelo Santino

submission deadline 31 Jul 2026 | 7 articles | Viewed by 16974 | Submission Open

Keywords: IBD; antioxidant; gut barrier; inflammation; natural compounds; microbiome; colon cancer; adjuvant; nutritional bioactive products; polyphenols

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Exploring New Frontiers in Oxidative Stress and Antioxidant Research: From Model Organisms to Human Disease

edited by

Marcello Ziosi

and

Gaetano Santulli

submission deadline 31 Jul 2026 | 6 articles | Viewed by 14777 | Submission Open

Keywords: oxidative stress; antioxidant therapeutics; cell death and survival pathways; cellular signaling networks; gene regulation and expression

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Compounds and Health Benefits of Mediterranean Functional Food

edited by

Stefania D'Angelo

submission deadline 31 Jul 2026 | 6 articles | Viewed by 13949 | Submission Open

Keywords: antioxidants; anti-inflammatory; anti-obesity; functional food; human health; Mediterranean diet; nutraceuticals; nutrition; oxidative stress; phytochemicals; polyphenols

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Plant Materials and Their Antioxidant Potential, 3rd Edition

edited by

Elisabeta Irina Geana

and

Ovidiu Tita

submission deadline 31 Jul 2026 | 5 articles | Viewed by 5573 | Submission Open

Keywords: antiseptic; antioxidant; volatile oil; compounds; fruits and vegetables; medicinal plants; agri-food industry; food ingredients; functional foods; nutraceuticals; food supplements; pharmaceutical products; antioxidant activity; oxidative stress; aging; anti-inflammatory activity; sustainable recovery; circular bioeconomy

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Bioactive Antioxidants: Structural Characterization, Synthetic Pathways, and Clinical Applications

edited by

Jolanta Flieger

submission deadline 31 Jul 2026 | 4 articles | Viewed by 4674 | Submission Open

Keywords: bioactive antioxidants; therapeutic potential; synthetic strategies; structural characterization

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Olive Antioxidants: Extraction, Biological Activity and Practical Applications—3rd Edition

edited by

Juan Fernández-Bolaños

and

Alejandra Bermudez-Oria

submission deadline 31 Jul 2026 | 2 articles | Viewed by 4408 | Submission Open

Keywords: antioxidant effect; olive oil; olive by-products; olive leaves; polyphenols; carotenoids; polysaccharide– polyphenol complexes; vitamin E; health; Mediterranean diet

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Metabolic Dysfunction and Oxidative Stress

edited by

Vinood B. Patel

and

Mohammed Gulrez Zariwala

submission deadline 31 Jul 2026 | 2 articles | Viewed by 4261 | Submission Open

Keywords: iron; mitochondria; oxidative stress; inflammation; metabolism; free radicals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Mitochondrial Dysfunction in Metabolic Disorders

edited by

Pablo M. García-Rovés

Steen Larsen

and Hugo J Alves-Figueiredo

submission deadline 31 Jul 2026 | 2 articles | Viewed by 3975 | Submission Open

Keywords: metabolic diseases; oxidative stress; mitochondrial dysfunction; antioxidant therapies; lifestyle interventions; gene therapies; mitochondrial transfer therapies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants in Counteracting Mycotoxin and Heavy Metal Toxicity

edited by

Shusheng Tang

and Xingyao Pei

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3878 | Submission Open

Keywords: natural antioxidants; mycotoxins; heavy metal; detoxification

Antioxidants and Antioxidant Mechanisms in the Prevention and Treatment of Infectious Diseases

edited by

Gabriele Carullo

Maria Dichiara

Valeria Tudino

and Sara Rossi

submission deadline 31 Jul 2026 | 2 articles | Viewed by 3827 | Submission Open

Keywords: antioxidants; infectious diseases; quorum sensing; inflammation; natural and synthetic antioxidants; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Bone Metabolic Diseases

edited by Zhongbo Liu

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2800 | Submission Open

Keywords: oxidative stress; bone metabolic diseases; osteoporosis; mitochondrial dysfunction; antioxidants; reactive species; osteoblast/osteoclast/osteocyte; Nrf2

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Lipotoxicity in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Its Therapeutic Control

edited by

Isao Ishii

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2537 | Submission Open

Keywords: metabolic dysfunction– associated steatotic liver disease (MASLD); metabolic dysfunction– associated steatohepatitis (MASH); fatty liver; lipotoxicity; ferroptosis; inflammation; fibrosis; Fenton reaction; thyroid hormone receptor-beta (THR-β ) agonist; peroxisome proliferator-activated receptor (PPAR) agonist; farnesoid X receptor (FXR) agonist

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Signaling in Chronic Diseases

edited by

Emma Borrelli

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2518 | Submission Open

Keywords: redox signaling; chronic oxidative diseases; redox modulator; oxidative stress; antioxidant; redox homeostasis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

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