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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Natural Antioxidants from Agro-Wastes and Food Waste: Characterization and Applications

edited by

Charles Manful

and Raymond H. Thomas

submission deadline 30 Oct 2026 | Viewed by 317 | Submission Open

Keywords: natural antioxidants; oxidative stress; carotenoids; terpenes; phytochemicals; polyphenols; functional foods; bioavailability; translational research; chronic diseases; optimization

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Innovative and Sustainable Antioxidants for Animal Nutrition

edited by

Luciana Rossi

Matteo Dell'Anno

and Vincenzo Chiofalo

submission deadline 30 Oct 2026 | Viewed by 258 | Submission Open

Keywords: precision nutrition; functional feed; oxidative stress; radical scavenging; natural extracts; disease prevention; agro-industrial by-products; one health

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Dietary Antioxidant Compounds and Animal Nutrition

edited by Alberto Baños Arjona and

Cristina Delgado-Andrade

submission deadline 30 Oct 2026 | Viewed by 215 | Submission Open

Keywords: dietary antioxidants; animal nutrition; oxidative stress; functional feed additives; livestock and aquaculture health; feed additives; stress resilience

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Green Extraction Technologies for Bioactive Compounds from Foods and Natural Products: Antioxidant Potential and Health Applications

edited by

Elena Ibáñez

and

Gerardo Álvarez-Rivera

submission deadline 30 Oct 2026 | 1 articles | Viewed by 153 | Submission Open

Keywords: food bioactivity; green extraction; antioxidant activity; functional ingredients; oxidative stress

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

NAD+ Regulation in Antioxidant Defense and Neurodegenerative Diseases

edited by

Irina G. Gazaryan

submission deadline 30 Oct 2026 | Viewed by 139 | Submission Open

Keywords: neurodegeneration; dementia; axonal degeneration; stroke; disease-modifying therapy; antioxidant defense; NAD assay

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in the Newborn, 2nd Edition

edited by Ru-Jeng Teng

submission deadline 30 Oct 2026 | Viewed by 128 | Submission Open

Keywords: newborn; neonatal diseases; oxidative stress; reactive oxygen species; antioxidant therapy

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants in Pharmaceuticals and Dermatocosmetology

edited by

Corina Danciu

submission deadline 31 Oct 2026 | 9 articles | Viewed by 29886 | Submission Open

Keywords: phytochemicals; antioxidant; pharmaceuticals; dermatocosmetic products; in vitro and in vivo evaluations; clinical trials

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Natural Antioxidants in Fruits and Vegetables in Human Health

edited by

Antonio Barberis

submission deadline 31 Oct 2026 | 4 articles | Viewed by 26553 | Submission Open

Keywords: antioxidants; anti-inflammation; oxidative stress; fruits; vegetables; oxidation reactions; functional foods

Oxidative Stress in Rare Diseases: Mechanisms, Implications, and Therapeutic Opportunities

edited by

Christophe Desterke

and

Jorge Mata-Garrido

submission deadline 31 Oct 2026 | 4 articles | Viewed by 10527 | Submission Open

Keywords: rare diseases; oxidative stress; free radicals; biomedicine; redox biomarkers; redox epigenetics; redox metabolism; redox control of protein function; ferroptosis

Antioxidant Capacity of Natural Products—3rd Edition

edited by

Younghwa Kim

submission deadline 31 Oct 2026 | 5 articles | Viewed by 7512 | Submission Open

Keywords: natural antioxidants; oxidative stress; phytochemicals; bioactive compounds; reactive oxygen species (ROS)

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

The Effect of Nutritional Intervention and Diet on Oxidative Stress and Human Diseases

edited by

Josep A. Tur

, Cristina Bouzas and

Margalida Monserrat-Mesquida

submission deadline 31 Oct 2026 | 2 articles | Viewed by 5194 | Submission Open

Keywords: nutrition; diet; oxidative stress; inflammation; human chronic diseases; supplements; cardiovascular diseases; diabetes; obesity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Food Proteins and Peptides as Antioxidants: Resource, Extraction, Functional Property and Application

edited by

, Di Li and

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2971 | Submission Open

Keywords: protein resources; protein extraction and characterization; functional properties of proteins; antioxidant activity; protein application

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Reactive Oxygen Species (ROS): Key Components in Infection Control, Wound Healing, and Cancer Therapy

edited by Christian Scharf

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2853 | Submission Open

Keywords: reactive oxygen species (ROS); oxidative stress; redox signaling; antioxidant defense; wound healing; biofilm eradication; infection control; cancer therapy; immune modulation; cold atmospheric plasma (CAP); plasma-activated media (PAM); translational redox medicine

(This special issue belongs to the Section ROS, RNS and RSS)

Role of Natural Antioxidant Compounds in Slowing Neurodegeneration

edited by

Jessica Maiuolo

submission deadline 31 Oct 2026 | 3 articles | Viewed by 2819 | Submission Open

Keywords: neurodegeneration; neurodegenerative diseases; plant extracts; natural compounds; phytochemicals; polyphenols; gut-microbiota; gut– brain axis; brain and short-chain fatty acids

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Nitric Oxide (NO) and Hydrogen Sulfide (H₂S) in Biology, Illness, and Therapies—3rd Edition

edited by

Eizo Marutani

submission deadline 31 Oct 2026 | 3 articles | Viewed by 2753 | Submission Open

Keywords: nitric oxide; hydrogen sulfide; persulfide/polysulfide; sulfur metabolism; redox reaction; interaction/crosstalk; antioxidants; disease; therapy; detection methods

(This special issue belongs to the Section ROS, RNS and RSS)

Redox Regulation of Membrane Transporters: Mechanisms and Implications

edited by

Fátima Martel

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1355 | Submission Open

Keywords: antioxidants; membrane transport; pathologies; modulation; redox potencial

Redox Regulation in Animal Reproduction—2nd Edition

edited by Zhongliang Jiang

submission deadline 31 Oct 2026 | 3 articles | Viewed by 1162 | Submission Open

Keywords: spermatogenesis; semen preservation; sperm survive; follicular atresia; oocyte maturation; granulosa cells; hormone regulation; autophagy; apoptosis; oxidative stress; signaling regulation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Homeostasis in Poultry/Animal Production―2nd Edition

edited by

Peter F. Surai

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1056 | Submission Open

Keywords: redox homeostasis; oxidative stress; antioxidants; transcription factors; immunity; inflammation; poultry; pigs; cattle

Oxidative Stress and Antioxidant Defense in Crop Plants, 3rd Edition

edited by

Marta Jańczak-Pieniążek

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1036 | Submission Open

Keywords: biotic and abiotic stress; oxidative stress; ROS; plant biostimulants; crop plants; antioxidant mechanisms; oxidative stress; antioxidant response; antioxidant enzymes

(This special issue belongs to the Section ROS, RNS and RSS)

Antioxidant and Antidiabetic Activities of Plant Matrices: Methods, Mechanisms, and Translational Relevance

edited by

Sabina Lachowicz-Wiśniewska

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1021 | Submission Open

Keywords: antioxidant assays; antidiabetic activity; α -glucosidase; α -amylase; DPP-IV; antiglycation/AGEs; tea (Camellia sinensis); wild plants; neglected and underutilized species (NUS); stachys; root and tuber crops; ultrasound; microwave; bioavailability; metabolomics; layer-by-layer; hydrogels; alginate; pectin; chitosan; zein; processing by-products

Natural Bioactive Compounds with Antioxidant and Anti-Inflammatory Potential: From Mechanisms to Applications

edited by

Vassilis Athanasiadis

submission deadline 31 Oct 2026 | 1 articles | Viewed by 691 | Submission Open

Keywords: plant-derived bioactive compounds; polyphenols and flavonoids; antioxidant and anti-inflammatory mechanisms; oxidative stress modulation; phytochemical extraction and characterization; bioaccessibility and bioavailability; functional food formulations; natural anti‑inflammatory agents; agricultural by-product valorization; cosmetic and food applications

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

The Role of Nutrition and Exercise in the Prevention and Treatment of Oxidative Stress-Associated Diseases—2nd Edition

edited by

Dejan Reljic

submission deadline 31 Oct 2026 | 1 articles | Viewed by 601 | Submission Open

Keywords: physical activity; exercise; nutrition; oxidative stress; antioxidant capacity; reactive oxygen species; redox status; chronic diseases; cardiovascular disease; obesity; metabolic syndrome; type 2 diabetes; cancer; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Redox Signalling Across Ocular Diseases: Mechanisms, Tissue-Specific Pathology, and Therapeutic Targets

edited by Mayuri Bhargava

submission deadline 31 Oct 2026 | 1 articles | Viewed by 410 | Submission Open

Keywords: oxidative stress; redox signaling; retinal diseases; corneal pathology; cataractogenesis; mitochondrial dysfunction; inflammation– oxidative stress crosstalk; antioxidant therapies; ocular surface disease; biomarkers of oxidative damage

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Aquaculture: A Synergistic Approach for Sustainable Aquatic Production—2nd Edition

edited by

Yukun Zhang

Amina Moss

and Saichiro Yokoyama

submission deadline 31 Oct 2026 | 1 articles | Viewed by 356 | Submission Open

Keywords: oxidative stress; aquatic animals; dietary antioxidants; reactive oxygen species (ROS); natural antioxidants; fish nutrition; antioxidant supplementation; environmental stressors; sustainable aquaculture; stress management

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Oxygen Species in Skeletal Muscle and Adipose Tissue

edited by Jan Górski and

Elzbieta Supruniuk

submission deadline 31 Oct 2026 | Viewed by 314 | Submission Open

Keywords: oxidative stress; antioxidants; myokines; adipokines; skeletal muscle; adipose tissue

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Inflammation in Osteoarthritis and Rheumatoid Arthritis

edited by

Katarzyna Piotrowska

and

Mateusz Bosiacki

submission deadline 31 Oct 2026 | Viewed by 292 | Submission Open

Keywords: proinflammatory gene transcription; markers of oxidative stress and antioxidant enzyme activity; targeted therapies in OA and RA; translational studies; experimental models including 3D chondrocyte cultures; antioxidant enzyme gene polymorphisms; impacts of diet/dietary supplements and physical activity on inflammatory processes and oxidative balance

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Quantum Biology and Redox Signaling

edited by

Margaret Ahmad

submission deadline 31 Oct 2026 | Viewed by 229 | Submission Open

Keywords: quantum biology; redox signaling; electron transfer; radical pair mechanisms; reactive oxygen species (ROS); spin chemistry; biological electron tunneling; oxidative stress and signaling; quantum effects in living systems; bioenergetics

(This special issue belongs to the Section ROS, RNS and RSS)

Oxidative Stress and Antioxidant Defenses in Aquatic Animals

edited by

Cristina Elena Trenzado Romero

and Laura María Pantoja Echevarría

submission deadline 31 Oct 2026 | Viewed by 174 | Submission Open

Keywords: aquatic animals; ecosystem; reactive oxygen species; aquaculture; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Methionine in Redox Signaling, Metabolic Regulation, and Disease

edited by

Jackob Moskovitz

submission deadline 31 Oct 2026 | Viewed by 171 | Submission Open

Keywords: methionine sulfoxide reductase; methionine-1; S-adenosylmethionine; redox regulation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advanced Bioanalytical Techniques in Antioxidant and Oxidative Stress Research

edited by Tomasz Ligor and

Magdalena Ligor

submission deadline 31 Oct 2026 | Viewed by 151 | Submission Open

Keywords: biomarkers of oxidative stress; antioxidants from natural sources; advanced chromatographic techniques; omics approaches

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Multi-Organ Effects of Alcohol Exposure: Oxidative Mechanisms and Antioxidant Protection

edited by

María Luisa Ojeda Murillo

and

Fátima Nogales Bueno

submission deadline 31 Oct 2026 | Viewed by 140 | Submission Open

Keywords: alcohol consumption; multi-organ damage; oxidative stress; nitrosative stress; antioxidants

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Recent Advances in Applications of Antioxidants in Livestock Health and Reproduction—2nd Edition

edited by Weijun Pang

submission deadline 31 Oct 2026 | Viewed by 123 | Submission Open

Keywords: antioxidants; livestock health; reproduction; production efficiency; disease-resistant ability

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Genetics and Epigenetics of Antioxidants

edited by

Jolanta Dorszewska

and

Richard Siow

submission deadline 31 Oct 2026 | Viewed by 104 | Submission Open

Keywords: antioxidants; oxidative stress; nutrigenetics; epigenetics; SOD; CAT; GPx; personalized nutrition; cancer; neurodegenerative diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Targeting Oxidative Stress in Ischemia/Reperfusion Injury

edited by Kenneth J. Dery

submission deadline 10 Nov 2026 | 3 articles | Viewed by 4711 | Submission Open

Keywords: ischemia/reperfusion injury; reactive oxygen species; redox-regulated molecular and cellular mechanism; antioxidant-based therapeutic strategies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Resilience in Mitochondrial Health and Disease: New Advances in Cellular Defense Mechanisms

edited by

Yuseok Moon

and

Ki Hyung Kim

submission deadline 10 Nov 2026 | 1 articles | Viewed by 2007 | Submission Open

Keywords: mitochondrial redox; mitochondria; cellular conditions; oxidative damage; redox homeostasis; cellular aging; metabolic disorders; cancer; inflammation; obesity; aging; mucosal diseases; neurodegenerative diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Plant‑Derived Essential Oils and Phytochemicals: Dual Antioxidant and Antimicrobial Mechanisms

edited by

Cristina-Mihaela Rîmbu

and

Cristina-Elena Horhogea

submission deadline 15 Nov 2026 | Viewed by 171 | Submission Open

Keywords: plant-derived essential oils and phytochemicals; redox modulation and antioxidant activity; antimicrobial mechanisms and applications

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Natural Antioxidants for Cosmetic Applications

edited by

Rita Cortesi

and

Maddalena Sguizzato

submission deadline 20 Nov 2026 | 4 articles | Viewed by 5581 | Submission Open

Keywords: cosmetic formulations; skin care; oxidative stress; photoprotection

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Role of Mitochondria and ROS in Health and Disease—2nd Edition

edited by

Paola Venditti

Gaetana Napolitano

and

Gianluca Fasciolo

submission deadline 20 Nov 2026 | 3 articles | Viewed by 3930 | Submission Open

Keywords: ROS; mitochondria; antioxidants; oxidative stress; neurological diseases; metabolic diseases; retinal diseases; mitochondrial disfunctions; mitochondria endoplasmic reticulum communication; mitochondrial bioenergetics; ageing; physical activity

(This special issue belongs to the Section ROS, RNS and RSS)

Antioxidants and Oxidative Stress at the Crossroads of Autophagy and Ferroptosis

edited by

Elzbieta Janda

and Flavia Biamonte

submission deadline 30 Nov 2026 | 4 articles | Viewed by 4864 | Submission Open

Keywords: antioxidants; oxidative stress; ferroptosis; autophagy; molecular mechanisms

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants: Multiple Mechanisms for Skin Protection and Skin Disease

edited by

Hang Ma

and

Jean Christopher Chamcheu

submission deadline 30 Nov 2026 | 4 articles | Viewed by 4860 | Submission Open

Keywords: natural products; mechanism(s) of action; multi-omics approaches; target identification; dermatological treatment; skin protection; inflammation; skin cancers; skin aging; cosmeceuticals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Radiation Exposure and Health: The Role of Oxidative Stress and Inflammatory Response

edited by

Siamak Haghdoost

and

Benjamin Frey

submission deadline 30 Nov 2026 | 2 articles | Viewed by 4365 | Submission Open

Keywords: radiation; inflammatory response; oxidative stress

Role of Antioxidants and Oxidative Stress in Neurodegenerative Diseases

edited by

Barbara Sottero

submission deadline 30 Nov 2026 | 2 articles | Viewed by 4193 | Submission Open

Keywords: neurodegenerative diseases; antioxidants; oxidative stress; Parkinson’ s disease; Alzheimer’ s disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Impact of Antioxidant and Anti-Inflammatory Functions of HDL in Diseases—3rd Edition

edited by

Carlo Cervellati

and

Judit Marsillach

submission deadline 30 Nov 2026 | 3 articles | Viewed by 3055 | Submission Open

Keywords: paraoxonases; oxidized LDL; high-density lipoproteins; metabolic diseases; apolipoproteins; cardiovascular disease; neurological disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Cardiovascular Diseases

edited by

Yongting Luo

Junjie Luo

and Peng An

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2906 | Submission Open

Keywords: cardiovascular disease; oxidative stress; antioxidant compound; mechanism; therapeutic target

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Therapies, Mitochondrial Function, and Transplantation Strategies: Mechanisms and Emerging Therapeutics

edited by

Junhwan Kim

and

P. Singh

submission deadline 30 Nov 2026 | 3 articles | Viewed by 2719 | Submission Open

Keywords: oxidative stress; antioxidant therapies; mitochondrial function; mitochondrial dysfunction

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Mitochondria, Redox and Pancreatic β-Cells: Maturation, Function and Inflammatory Stress

edited by Sarah Zangen

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2074 | Submission Open

Keywords: pancreatic β -cell mitochondria; redox; ETC dysfunction; electron ROS/RNS; mitophagy; UPR^mt; antioxidant defenses; cytokines; inflammasome; iPSC/islet organoids; biomarkers; therapeutics

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Food Matrices: From Analytical Advances to Circular and Sustainable Applications

edited by

Sara Jaramillo-Carmona

and

Rafael Guillén Bejarano

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1376 | Submission Open

Keywords: food matrix; bioaccesibility; bioavailability; functionality; by-products; valorization; circular economy

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Next-Generation Insights into Anthocyanins and Phytopigments: Bioactivity, Bioavailability, and Health Impacts

edited by

Agustín G. Asuero

Noelia Tena

and

Julia Martín

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1119 | Submission Open

Keywords: anthocyanins; phytopigments; antioxidant activity; bioavailability; metabolic transformation; dietary supplements; chronic disease prevention

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Melanoma and Redox Dynamics: A Crucial Tug-of-War in Tumor Onset and in Therapy Response

edited by

Cinzia Domenicotti

and

Barbara Marengo

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1079 | Submission Open

Keywords: melanoma; redox homeostasis; ROS; antioxidants; therapy resistance; cancer metabolism; mitochondria; epigenetic changes; innovative therapeutic and experimental approaches

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Prevention and Treatment of Diabetes

edited by Karima Zitouni and Kenneth Earle

submission deadline 30 Nov 2026 | 2 articles | Viewed by 903 | Submission Open

Keywords: diabetic vasculopathy; oxidative stress; type 2 diabetes; antioxidant defenses

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

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