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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Sensory Function and Perception in Dementia

edited by

Andrea Tales

submission deadline 5 May 2025 | 1 articles | Viewed by 1118 | Submission Open

Keywords: ageing ; cognitive decline ; objectively measured effects of sensory dysfunction in people with cognitive decline ; subjective reports of sensory dysfunction in people with cognitive decline

(This special issue belongs to the Section Sensory and Motor Neuroscience)

The Latest Research on Drug Treatment of Epilepsy

edited by Alberto E. Musto and Luis Pacheco

submission deadline 5 May 2025 | Viewed by 80 | Submission Open

Keywords: epilepsy; neuroinflammation; seizures; cannabinoid

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Stress, Resilience and Susceptibility

edited by Elaine Gavioli

submission deadline 15 May 2025 | 1 articles | Viewed by 1742 | Submission Open

Keywords: stress; resilience; vulnerability; psychiatric disorders; biomarkers

(This special issue belongs to the Section Neuropharmacology and Neuropathology)

Non-Invasive Brain Stimulation in Neurological Diseases and Neurorehabilitation

edited by

Maryam Zoghi

submission deadline 15 May 2025 | Viewed by 245 | Submission Open

Keywords: non-invasive brain stimulation; transcranial direct-current stimulation; transcranial magnetic stimulation; neurorehabilitation; neurological diseases; stroke; Parkinson's disease; multiple sclerosis; chronic pain

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Molecular and Cellular Biology of Brain Tumors and Neuro-Oncology

edited by Rafael Roesler

submission deadline 16 May 2025 | 1 articles | Viewed by 1217 | Submission Open

Keywords: glioma; medulloblastoma; ependymoma; brain cancer; central nervous system tumor; neuro-oncology

(This special issue belongs to the Section Neuro-oncology)

Current Perspectives on the Management of Acute-Phase Ischemic Stroke

edited by Stefano Caproni, Ettore Nicolini and Soffien Ajmi

submission deadline 16 May 2025 | Viewed by 266 | Submission Open

Keywords: acute ischemic stroke; endovascular thrombectomy; thrombolysis; clinical treatment

(This special issue belongs to the Section Neurorehabilitation)

The Application of EEG in Neurorehabilitation

edited by

Ryouhei Ishii

submission deadline 19 May 2025 | 5 articles | Viewed by 3646 | Submission Open

Keywords: electroencephalography (EEG); neurorehabilitation; neural plasticity; personalized treat-ment strategies; brain– computer interfaces

(This special issue belongs to the Section Computational Neuroscience and Neuroinformatics)

The Role of Glia in Inflammatory Processes

edited by

Charles Elias Assmann

and Margarete Dulce Bagatini

submission deadline 19 May 2025 | 1 articles | Viewed by 808 | Submission Open

Keywords: neuroinflammation; neurodegenerative and psychiatric disorders; microglia; astrocytes; purinergic signaling; bioactive and natural compounds; immunopharmacology and immunotoxicology; oxidative and nitrosative stress; neuroimaging; neuroscience and behavior

(This special issue belongs to the Section Neuroglia)

So, What? What Does Contemporary ADHD Research Tell Us about Lived Experiences?

edited by

Conor Mc Guckin

, Kate Carr-Fanning and Aoife Lynam

submission deadline 19 May 2025 | Viewed by 441 | Submission Open

Keywords: ADHD; social model; participant voice; educational inclusion; social inclusion; transition planning; family experience; early intervention; policy; advocacy

(This special issue belongs to the Section Developmental Neuroscience)

Advances in the Pharmacologic Treatment of Depression, Anxiety, and Other Psychiatric Disorders

edited by Danielle S. Cha

submission deadline 20 May 2025 | Viewed by 72 | Submission Open

Keywords: mental health; mental illness; treatment; hypothesis driven; burden of disease

(This special issue belongs to the Section Neuropsychiatry)

Mechanisms That Support Music Learning and Development

edited by Jennifer A. Bugos

submission deadline 20 May 2025 | Viewed by 23 | Submission Open

Keywords: music; music therapy; neurophysiological research; cognitive development; music cognition; performance; auditory processing

(This special issue belongs to the Section Behavioral Neuroscience)

Anosognosia and the Determinants of Self-Awareness

edited by

Guido Gainotti

submission deadline 25 May 2025 | Viewed by 255 | Submission Open

Keywords: anosognosia; disease unawareness; stroke patients; Alzheimer’ s disease; self-awareness; hemiplegia; unilateral neglect; Anton syndrome; insight

(This special issue belongs to the Section Neuropsychology)

Neuromodulation and Neurostimulation in Psychiatric Disorders

edited by

Takuma Inagawa

submission deadline 25 May 2025 | Viewed by 142 | Submission Open

Keywords: brain stimulation; rTMS; ECT; depression; OCD

(This special issue belongs to the Section Neuropsychiatry)

Genetics of Neurodegenerative Diseases: Retrospect and Prospect

edited by

Kallirhoe Kalinderi

and

Vasileios T. Papaliagkas

submission deadline 30 May 2025 | 2 articles | Viewed by 3350 | Submission Open

Keywords: Alzheimer's disease (AD); Parkinson's disease (PD); amyotrophic lateral sclerosis (ALS); multiple sclerosis; neurodegeneration; protein aggregation; therapy; pharmacogenetics; gene; nutrigenomics

(This special issue belongs to the Section Neurodegenerative Diseases)

Diagnosis, Treatment, and Prognosis of Neuromuscular Disorders

edited by

Vincenzo Di Stefano

and

Claudia Vinciguerra

submission deadline 30 May 2025 | 1 articles | Viewed by 2142 | Submission Open

Keywords: neuromuscular disorders; neurogenetics; neuroimmunology; polyneuropathy; myopathy; neuromuscular junction disease; diagnosis; prognosis; treatment; rehabilitation

(This special issue belongs to the Section Neuromuscular and Movement Disorders)

Novel Neuroimaging of Neurological and Psychiatric Disorders

edited by

Darrin J. Lee

submission deadline 30 May 2025 | Viewed by 145 | Submission Open

Keywords: neuroimaging; diagnosis; treatment; psychiatric diseases; brain structure

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Headache: Advances in Pathophysiology, Clinical Presentations and Therapeutic Options

edited by

Alessandro Viganò

submission deadline 30 May 2025 | Viewed by 109 | Submission Open

Keywords: migraine; comorbidities; pathophysiology; pharmacological interventions; non-pharmacological interventions; mechanisms

(This special issue belongs to the Section Systems Neuroscience)

Relationships Between Disordered Sleep and Mental Health

edited by Anne M. Fink

submission deadline 31 May 2025 | 2 articles | Viewed by 2517 | Submission Open

Keywords: circadian rhythms; depression; genetics and genomics; rapid eye movement sleep behavior disorder; schizophrenia; sleep deprivation; shift– work sleep disorder; substance use disorder; suicide

(This special issue belongs to the Section Neuropsychiatry)

Brain Tumors: From Molecular Basis to Therapy

edited by Paolo Tini and Giuseppe Minniti

submission deadline 31 May 2025 | 2 articles | Viewed by 2099 | Submission Open

Keywords: brain tumors; molecular pathways; targeted therapy; diagnostic biomarkers; predictive biomarkers; therapeutic resistance

(This special issue belongs to the Section Neuro-oncology)

Aging-Related Changes in Memory and Cognition

edited by Anna Christakou

submission deadline 31 May 2025 | 2 articles | Viewed by 1373 | Submission Open

Keywords: aging; quality of life; cognitive/physical health; neurodegenerative diseases; geriatric physiotherapy; memory; cognition; attention; prevention; therapeutic treatments

(This special issue belongs to the Section Neurodegenerative Diseases)

Brain Stimulation Treatments for Memory Disorders

edited by

Windy McNerney

and

John Philip Coetzee

submission deadline 31 May 2025 | 1 articles | Viewed by 883 | Submission Open

Keywords: DBS; tACS; tDCS; TUS; memory loss; plasticity; cognition; biochemistry

(This special issue belongs to the Section Systems Neuroscience)

Understanding the Functioning of Brain Networks in Health and Disease

edited by

Moses O. Sokunbi

submission deadline 31 May 2025 | Viewed by 182 | Submission Open

Keywords: brain networks; cognitive dysfunction; diffusion tensor imaging (DTI); electroencephalography (EEG); functional connectivity; functional magnetic resonance imaging (fMRI); magnetoencephalography (MEG); neurological disorders; neuroplasticity; psychiatric disorders; artificial intelligence; deep learning; neural networks; signal complexity

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

State of the Art in Multisensory Integration: Predicting Age-Related Clinical Outcomes

edited by Jeannette R. Mahoney

submission deadline 1 Jun 2025 | Viewed by 265 | Submission Open

Keywords: multisensory integration; sensorimotor integration; aging; mobility; balance; falls; cognition; dementia

(This special issue belongs to the Section Sensory and Motor Neuroscience)

The Gut–Brain Axis: Exploring the Interactions Between the Microbiota and the Nervous System

edited by Kyle Gobrogge

submission deadline 1 Jun 2025 | Viewed by 23 | Submission Open

Keywords: gut– brain axis; microbiota– neuron interactions; neurological functions and disorders; animal models; behavior and cognition

(This special issue belongs to the Section Neural Control of Peripheral Function)

The Use of Chemogenetics and Optogenetics on Understanding the Neurobiology of Brain Disorders

edited by

Sandesh Panthi

and

Marc Ekker

submission deadline 6 Jun 2025 | Viewed by 573 | Submission Open

Keywords: chemogenetics; optogenetics; DREADDs; brain disorders; neurobiology of disease

From Bench to Bedside: Motor–Cognitive Interactions—2nd Edition

edited by

Daniele Corbo

submission deadline 10 Jun 2025 | 2 articles | Viewed by 2324 | Submission Open

Keywords: motor control and motor learning; movement; cognitive functions; falls; diagnosis; intervention; cognitive– motor training; cognition; fMRI

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Current Research in Neurosurgery

edited by

Roberto Altieri

, Manlio Barbarisi and Lucas Alverne Freitas De Albuquerque

submission deadline 10 Jun 2025 | Viewed by 416 | Submission Open

Keywords: CSN tumor; glioblastoma; skull base; vertebral metastasis; spinal surgery; cerebral aneurysm; AVM; cavernoma; epilepsy

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Biomarkers in Neurodegenerative Diseases: Advancements and Future Directions

edited by Fausto Roveta

submission deadline 10 Jun 2025 | Viewed by 148 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; neurodegenerative disorders; biomarkers; neuroimaging

(This special issue belongs to the Section Neurodegenerative Diseases)

Role of Inflammation, Oxidative Stress, and Metabolic Dysfunction in Neurodevelopmental and Neurodegenerative Diseases: Pharmacological Targets and Therapeutic Interventions

edited by

Ansab Akhtar

submission deadline 13 Jun 2025 | 4 articles | Viewed by 5385 | Submission Open

Keywords: neuroinflammation; oxidative stress; mitochondrial dysfunction; metabolism; metabolomics; neurodegenerative diseases; neurodevelopmental diseases; pharmacological targets; potential drugs

(This special issue belongs to the Section Neurodegenerative Diseases)

Mental Health: From a Neurobiology Perspective

edited by

Zuleide Maria Ignácio

and

Margarete Dulce Bagatini

submission deadline 13 Jun 2025 | 1 articles | Viewed by 1950 | Submission Open

Keywords: neurobiology; mental health; psychiatric disorders; neurotransmission; signaling pathway; genetic and epigenetic factors; neurodevelopment; inflammation; therapeutic interventions; translational and clinical research

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Exploration of the Brain Structural Changes in Patients with Mental Illness

edited by

Fengyu Zhang

submission deadline 15 Jun 2025 | Viewed by 173 | Submission Open

Keywords: psychiatric diseases; human brain connectome; biomarkers; endophenotypes

(This special issue belongs to the Section Neuropsychiatry)

Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease

edited by Yuta Katsumi,

Deepti Putcha

and Bradford C. Dickerson

submission deadline 15 Jun 2025 | Viewed by 55 | Submission Open

Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’ s disease; prognostication; brain imaging; neuromodulation; interventions

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

New Challenges in the Study of Cognitive Impairment in Parkinson’s Disease

edited by

Sonia Di Tella

and Laura Colautti

submission deadline 16 Jun 2025 | 2 articles | Viewed by 1817 | Submission Open

Keywords: Parkinson’ s disease; cognitive impairment; assessment; intervention; executive functions; learning; decision making; creativity; cognitive reserve

(This special issue belongs to the Section Neurodegenerative Diseases)

Molecular Motors in Neuronal Homeostasis and Neurodegeneration

edited by

Daniel José Barbosa

and

Ana Filipa Sobral

submission deadline 20 Jun 2025 | Viewed by 499 | Submission Open

Keywords: molecular motors; kinesins; dynein; myosins; neuronal homeostasis; neuronal development; cellular trafficking; synaptic plasticity; biomarkers of early diagnosis; neurodegeneration

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Neurofunctional Basis of Language Processing—2nd Edition

edited by

Roozbeh Rezaie

and

Vahab Youssof Zadeh

submission deadline 20 Jun 2025 | Viewed by 86 | Submission Open

Keywords: language neurological disorders; non-invasive; brain mapping; neural networks; plasticity

(This special issue belongs to the Section Neurolinguistics)

Neuropsychological Impact and Quality of Life in Chronic Illness

edited by Nicoletta Ciccarelli

submission deadline 20 Jun 2025 | Viewed by 70 | Submission Open

Keywords: chronic disease; HIV; cancer; cardiovascular disease; neurodegeneration; aging; cognitive impairment; cognitive evaluation; quality of life; patient reported outcome (PRO) measures

(This special issue belongs to the Section Neuropsychology)

Neurosurgery: Minimally Invasive Surgery in Brain and Spine

edited by Christopher Ahuja

submission deadline 25 Jun 2025 | Viewed by 94 | Submission Open

Keywords: minimally invasive surgery; neurosurgery; brain; spine

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Multisensory Perception of the Body and Its Movement

edited by Monica Gori, Lara Coelho and Silvia Zanchi

submission deadline 27 Jun 2025 | Viewed by 124 | Submission Open

Keywords: body; space; spatial navigation; development; blindness multisensory

(This special issue belongs to the Section Sensory and Motor Neuroscience)

What Impact Does Lack of Sleep Have on Mental Health?

edited by

Haitham Jahrami

Seithikurippu R. Pandi-Perumal

and

Khaled Trabelsi

submission deadline 28 Jun 2025 | 2 articles | Viewed by 3539 | Submission Open

Keywords: ADHD; Alzheimer's; anxiety; autism; bipolar disorder; CBT-I; chronotherapy; circadian rhythm; cognitive function; depression; eating disorders; emotional regulation; epilepsy; executive function; insomnia; jet lag; memory consolidation; mental health; multiple sclerosis; neurobiological mechanisms; neurodevelopmental disorders; neuropsychiatric disorders; OCD; Parkinson's disease; personality disorders; PTSD; schizophrenia; self-harm; shift work; sleep deprivation; sleep disturbances; sleep quality; social cognition; substance use disorders; suicidal ideation; wearable technology

(This special issue belongs to the Section Neuropsychiatry)

Integrating Advanced Imaging Techniques and Computational Models in Headache Research

edited by Catherine S. Hubbard

submission deadline 28 Jun 2025 | Viewed by 69 | Submission Open

Keywords: personalized medicine; migraine; headache disorders; machine learning; deep learning; neuroimaging; animal models; neuromodulation; fMRI; neural networks

(This special issue belongs to the Section Neuroscience of Pain)

New Advances in Neuroimmunology and Neuroinflammation

edited by

Junhui Wang

Xueping Chen

, Jing Sun and Matheus Uba Chupel

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2514 | Submission Open

Keywords: neuroinflammation; neuroimmunology; glia; neurodegenerative diseases; cytokines; chemokines

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

The Relationship Between Sleep and the Brain: New Insights into Sleep Disorders and Their Effects on Mental Health, Cognition, and Quality of Life

edited by

Giuseppe Barbato

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1939 | Submission Open

Keywords: sleep; REM sleep; circadian rhythm; melatonin; mood disorders; delta sleep; clock genes

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

New Advances in the Development of New Drugs and Treatment Targets for Brain Cancers (2nd Edition)

edited by

Luis Ibarra

Laura Natalia Milla Sanabria

and

Nuria Arias-Ramos

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1300 | Submission Open

Keywords: gliomas; targeted therapy; blood– brain barrier; tumor microenvironment; molecular and cellular biology

(This special issue belongs to the Section Neuro-oncology)

Minimally Invasive Surgery for Brain and Skull Base Tumors

edited by

Carmine Antonio Donofrio

submission deadline 30 Jun 2025 | 1 articles | Viewed by 901 | Submission Open

Keywords: minimally invasive surgery; keyhole approaches; endoscopic surgery; stereotactic surgery; parafascicular surgery; brain tumors; neuro-oncology; skull base tumors

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Clinical Research on Sleep Disorders: Opportunities and Challenges

edited by

Pasquale Tondo

submission deadline 30 Jun 2025 | 1 articles | Viewed by 870 | Submission Open

Keywords: innovation; personalized management; sleep disorders; telemonitoring; treatment

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Neural Correlates of Art and Multisensory Perception

edited by

Letizia Palumbo

Zaira Cattaneo

and