Special Issues

Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Liquid Biopsy in Cancer 2.0 submission deadline 20 Oct 2025 | 7 articles | Viewed by 11128 | Submission Open
Keywords: circulating biomarkers; clinical utility; circulating tumor DNA; circulating tumor cells; exosomes; circulating RNA; precision medicine
(This special issue belongs to the Section Cancer Therapy)
What’s behind the Scenes? New Insights in Endometrial Cancer Management and Risk Stratification
edited by
submission deadline 20 Oct 2025 | 2 articles | Viewed by 6792 | Submission Open
Keywords: endometrial cancer; molecular classification; surgical staging; surgery; target therapy; gynecologic oncology; precision medicine; immunohistochemistry
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Salivary Gland Carcinoma: 2nd Edition
edited by
submission deadline 20 Oct 2025 | Viewed by 7 | Submission Open
Keywords: salivary gland tumors; head and neck cancer; facial nerve preservation; facial nerve reconstruction; facial nerve sacrifice; parotid cancer; parotidectomy; prognostic factors
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Gastrointestinal Cancer Surgery
edited by Florian Primavesi and
submission deadline 31 Oct 2025 | Viewed by 121 | Submission Open
Keywords: gastrointestinal cancer surgery; precision surgery; personalized medicine; robotics; pathology; colorectal cancer; stomach cancer; pancreatic cancer; hepatocellular cancer; biliary tract cancer
(This special issue belongs to the Section Cancer Therapy)
Cancer Inhibitory Receptors and Related Cancer Immunotherapy
edited by Keqiang Chen, Feng Zhu and Xin Li
submission deadline 31 Oct 2025 | Viewed by 45 | Submission Open
Keywords: cancer inhibitory receptors; ligands for inhibitor receptors; immune checkpoint inhibitors; cancer cells; immune cells; non-immune cells; inhibitor receptor pathways; immune checkpoint blockade therapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Prognosis and Treatment of Cutaneous Melanoma (2nd Edition)
edited by
submission deadline 31 Oct 2025 | Viewed by 29 | Submission Open
Keywords: prognosis; melanoma; adjuvant; germline; somatic; genetic; epigenetic; neoadjuvant
(This special issue belongs to the Section Cancer Therapy)
Advances in Thoracic Oncology Research
edited by
submission deadline 1 Nov 2025 | 1 articles | Viewed by 1295 | Submission Open
Keywords: lung cancer; mediastinal; thymic; neuroendocrine; robotic; VATS; chest wall; chemotherapy; immunotherapy; radiotherapy
(This special issue belongs to the Section Cancer Therapy)
Aberrant Cytokine Receptor Signaling in Hematological Cancers and Proliferative Disorders
edited by
submission deadline 20 Nov 2025 | Viewed by 211 | Submission Open
Keywords: cytokine receptor; signaling; leukemia; lymphoma; myeloproliferative neoplasm; hematology; oncology
(This special issue belongs to the Section Tumor Microenvironment)
Immunotherapy in the Management of Hematologic Malignancy
edited by Mohammad S. Hossain
submission deadline 30 Nov 2025 | 6 articles | Viewed by 10746 | Submission Open
Keywords: allo/auto HSCT; GvHD; immunotherapy; viral infection; hematologic malignancy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
New Approaches in the Treatment of Hepatocellular Carcinoma and Liver Tumor
edited by Riccardo Inchingolo, Stavros Spiliopoulos and Riccardo Memeo
submission deadline 30 Nov 2025 | 1 articles | Viewed by 375 | Submission Open
Keywords: hepatocellular carcinoma; cirrhosis; liver; interventional oncology; trans-arterial chemo embolization; selective internal radiation therapy; ablation; radiology
(This special issue belongs to the Section Cancer Therapy)
Mesothelioma: Diagnosis and Therapy
edited by
submission deadline 30 Nov 2025 | Viewed by 26 | Submission Open
Keywords: malignant pleural mesothelioma; diagnostics; immunotherapy treatment; surgical treatments; intrapleural therapy
(This special issue belongs to the Section Cancer Therapy)
Post-transcriptional Regulation of Cancer-Related Processes
edited by
submission deadline 1 Dec 2025 | 1 articles | Viewed by 1767 | Submission Open
Keywords: microRNAs; long-non-coding RNA; RNA-binding proteins; stress granules; P-bodies
(This special issue belongs to the Section Tumor Microenvironment)
Latest Breakthroughs in Tumor Immune Microenvironment: From Cellular Discovery to Cutting-Edge Technology submission deadline 5 Dec 2025 | 4 articles | Viewed by 4749 | Submission Open
Keywords: tumor microenvironment; natural food extracts; molecular markers; abscopal effect; RT technology; prognosis; side effects and abscopal effects
(This special issue belongs to the Section Tumor Microenvironment)
New Molecular Targets and Emerging Approaches to Target Cancer Stem Cells
edited by and Mónica Fernandes
submission deadline 15 Dec 2025 | 3 articles | Viewed by 5117 | Submission Open
Keywords: cancer stem cells; plasticity; microenvironmental heterogeneity; resistance to therapy; targeted therapies; immune surveillance avoidance; invasion; metastasis
(This special issue belongs to the Section Tumor Microenvironment)
Biomarkers for Treatment Prediction, Prognosis and Early Detection of Gynecologic Cancer
edited by Brian S Finkelman, Rachelle P Mendoza and Hani Katerji
submission deadline 15 Dec 2025 | 4 articles | Viewed by 3875 | Submission Open
Keywords: biomarkers; endometrial cancer; uterine cancer; cervical cancer; ovarian cancer; vulvar cancer; treatment prediction; prognosis; early detection
(This special issue belongs to the Section Cancer Biomarkers)
Outcome Analysis and Predictive Insights in Soft Tissue Sarcomas: leveraging Clinical Data and Integrating Modelling
edited by
submission deadline 15 Dec 2025 | Viewed by 113 | Submission Open
Keywords: bone sarcomas; soft tissue sarcomas; outcome analysis; predictive modelling; prognostic biomarkers; therapeutic impact; clinical data integration; survivorship prediction; patient trajectories; sarcoma management
(This special issue belongs to the Section Methods and Technologies Development)
Molecular Biology, Diagnosis and Management of Cervical Cancer
edited by , , Thomas Vrekoussis and
submission deadline 31 Dec 2025 | 6 articles | Viewed by 9496 | Submission Open
Keywords: cervical cancer; molecular biology; lymph node dissection; sentinel lymph node mapping; sentinel lymph node dissection; surgery; systemic therapy; radiotherapy; fertility preservation; molecular targeted therapies
(This special issue belongs to the Section Molecular Cancer Biology)
Advances in Clinical Trials: Outcome, Innovations, Challenges, and Ethical Practice in Cancer Research 2024–2025
edited by and David R. Gandara
submission deadline 31 Dec 2025 | Viewed by 929 | Submission Open
Keywords: phase I; phase II; phase III; phase IV; clinical trials; features; design; implementation; outcomes
(This special issue belongs to the Section Clinical Research of Cancer)
The Applications of Artificial Intelligence in Gastroenterology
edited by , and Louis H. S. Lau
submission deadline 31 Dec 2025 | Viewed by 149 | Submission Open
Keywords: artificial intelligence; gastroenterology; endoscopy; inflammatory bowel diseases
(This special issue belongs to the Section Cancer Therapy)
Insights from the Editorial Board Member
edited by
submission deadline 31 Dec 2025 | Viewed by 133 | Submission Open
Keywords: cancer therapeutics; cancer biomarkers; precision medicine; cancer genomics; cancer immunology; cancer biology; clinical trials; cancer epidemiology and prevention; tumor microenvironment and metastasis; cancer informatics
Fertility Preservation in Gynecological Cancer submission deadline 31 Dec 2025 | Viewed by 126 | Submission Open
Keywords: gynecological cancer; fertility preservation; surgery treatments; fertility sparing; psychological implication
(This special issue belongs to the Section Methods and Technologies Development)
Feature Papers in Section "Tumor Microenvironment"
edited by
submission deadline 31 Dec 2025 | Viewed by 100 | Submission Open
Keywords: tumor microenvironment; cancer progression; interactions; therapeutic targeting; immune response
(This special issue belongs to the Section Tumor Microenvironment)
Innovations in Addressing Disparities in Cancer submission deadline 31 Dec 2025 | Viewed by 85 | Submission Open
Keywords: artificial intelligence on health equity; artificial intelligence and machine learning technologies in cancer care; genomic testing and biomarkers; AI in social determinants of health; health justice; precision medicine and health informatics; innovative cancer care delivery model for overcoming health disparity; equity lens; racial differences in the immunological landscape; racial differences in treatment and disease outcome
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advances in the Pathogenesis of Hematopoietic Neoplasms submission deadline 31 Dec 2025 | Viewed by 73 | Submission Open
Keywords: B cell lymphoma; T cell lymphoma; Hodgkin lymphoma; leukemia; myeloma; pathogenesis; genomics; microenvironment
(This special issue belongs to the Section Cancer Pathophysiology)
Surgical Aspects of Ovarian/Tubal/Peritoneal Cancer Management submission deadline 31 Dec 2025 | Viewed by 70 | Submission Open
Keywords: primary cytoreduction; interval cytoreduction; neoadjuvant chemotherapy
(This special issue belongs to the Section Cancer Therapy)
New Perspectives in the Management of Breast Cancer submission deadline 31 Dec 2025 | Viewed by 53 | Submission Open
Keywords: breast cancer; treatment; nutrition; physical exercise; psychosocial impact
(This special issue belongs to the Section Cancer Therapy)
Cost-Effectiveness Studies in Cancers submission deadline 31 Dec 2025 | Viewed by 31 | Submission Open
Keywords: cancer therapies; cost-effectiveness; cost-utility; cost-consequence; treatment economic impact; health economic; economic sustainability; public health; decision analytical models.
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
New Insights in the Management of Resectable Esophageal Malignancy
edited by and Dimitrios A. Theodorou
submission deadline 31 Dec 2025 | Viewed by 28 | Submission Open
Keywords: esophageal cancer; perioperative chemotherapy; radiotherapy; immunotherapy; radical surgical resection
(This special issue belongs to the Section Methods and Technologies Development)
Novel Treatments for Ocular and Periocular Cancers
edited by
submission deadline 31 Dec 2025 | Viewed by 10 | Submission Open
Keywords: ocular cancer; intraocular tumor; retinoblastoma; uveal melanoma
(This special issue belongs to the Section Cancer Therapy)
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