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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Contemporary Thoracic Surgery: Technology and Innovation
edited by
submission deadline 30 Jun 2026 | Viewed by 9 | Submission Open
Keywords: thoracic surgery; robotic surgical procedures; video-assisted thoracoscopic surgery; thoracic neoplasms; minimally invasive surgical procedures; surgical outcomes; lung cancer surgery; surgical innovation
(This special issue belongs to the Section Methods and Technologies Development)
Targeted Radiotracers for Molecular Imaging and Therapy in Cancer submission deadline 30 Jun 2026 | Viewed by 8 | Submission Open
Keywords: theranostic; radionuclide molecular imaging; targeted therapy; specificity; selectivity; personalized medicine; radiopharmaceuticals
(This special issue belongs to the Section Methods and Technologies Development)
Circadian Rhythms, Cancers and Chronotherapy (2nd Edition)
edited by , and Esra Tasali
submission deadline 30 Jun 2026 | Viewed by 7 | Submission Open
Keywords: drug development and chronotherapy; chemotherapy; immunotherapy; targeted agents; radiotherapy; surgery; circadian host or tumor biomarkers; electronic patient-reported outcomes; circadian rhythms and sleep; sex- and age specificities; clinical trial designs; mathematical models and artificial intelligence; digital healthcare; telemedicine and logistics
(This special issue belongs to the Section Cancer Therapy)
Urological Cancer: Epidemiology and Genetics
edited by Ilir Agalliu and Evan Kovac
submission deadline 30 Jun 2026 | Viewed by 7 | Submission Open
Keywords: environmental factors; lifestyle; genetic susceptibility; biomarkers; prostate cancer; bladder cancer; kidney cancer
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Therapeutic Strategies for Prostate Cancer
edited by Angelo Naselli and
submission deadline 1 Jul 2026 | 4 articles | Viewed by 10026 | Submission Open
Keywords: immunotherapy; radiation therapy; hormone therapy; targeted therapies
(This special issue belongs to the Section Cancer Therapy)
The Role of Radiotherapy, Immunotherapy and New Surgical Techniques in the Treatment of Lung Neoplasms
edited by
submission deadline 1 Jul 2026 | 3 articles | Viewed by 5418 | Submission Open
Keywords: radiotherapy; immunotherapy; new surgical techniques; lung cancer
(This special issue belongs to the Section Cancer Therapy)
Pediatric Brain Tumors: Symptoms, Diagnosis and Treatments
edited by Christian Ott and Julius Höhne
submission deadline 1 Jul 2026 | 3 articles | Viewed by 3330 | Submission Open
Keywords: MRI/CT scans; radiation therapy; chemotherapy; combined therapy
(This special issue belongs to the Section Cancer Therapy)
Advancing CAR-T Cell Therapy: The Next Evolution in Breast Cancer Treatment
edited by
submission deadline 1 Jul 2026 | Viewed by 33 | Submission Open
Keywords: CAR-T cell therapy; breast cancer; triple-negative breast cancer (TNBC); HER2-positive breast cancer; tumor microenvironment; immunotherapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Chemotherapy for Metastatic Head and Neck Squamous Cell Carcinomas
edited by Ken Saijo
submission deadline 15 Jul 2026 | Viewed by 45 | Submission Open
Keywords: head and neck squamous cell carcinomas; HNSCC; immune checkpoint inhibitor; biomarker; chemotherapy
(This special issue belongs to the Section Cancer Metastasis)
Tumor Microenvironment of Breast Cancer–2nd Edition
edited by
submission deadline 15 Jul 2026 | Viewed by 15 | Submission Open
Keywords: breast cancer; tumor microenvironment; TME; stromal cells
(This special issue belongs to the Section Tumor Microenvironment)
Current Status and Clinical Developments in Lung Cancer: What to Expect from Emerging Drugs? (2nd Edition) submission deadline 20 Jul 2026 | Viewed by 55 | Submission Open
Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors (ICIs); target therapy; tyrosine kinase inhibitors (TKIs); cancer biomarkers
(This special issue belongs to the Section Cancer Therapy)
HIV-Associated Lymphoid Neoplasms (2nd Edition) submission deadline 20 Jul 2026 | Viewed by 4 | Submission Open
Keywords: B-cell lymphoma; HIV; AIDS; Epstein– Barr virus; epidemiology; pathogenesis; prognosis
(This special issue belongs to the Section Infectious Agents and Cancer)
Image Assisted High Precision Radiation Oncology
edited by Christopher Njeh and Senthamizhchelvan Srinivasan
submission deadline 25 Jul 2026 | Viewed by 8 | Submission Open
Keywords: image-guided radiation therapy (IGRT); MR-guided radiation therapy (MRgRT); adaptive radiation therapy (ART); radiomics and AI in imaging; multi-modal imaging (CT; MRI; PET); treatment planning and verification; real-time tracking and motion management; stereotactic radiotherapy (SBRT/SRS); imaging biomarkers; dose accumulation and image registration
(This special issue belongs to the Section Methods and Technologies Development)
Evolving Understanding of the Epidemiology of Thyroid Cancer submission deadline 31 Jul 2026 | 2 articles | Viewed by 2808 | Submission Open
Keywords: thyroid cancer; epidemiology; incidence; time trends; mortality
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Recent Developments on PET-CT in Multiple Myeloma
edited by Carmelo Caldarella
submission deadline 31 Jul 2026 | Viewed by 83 | Submission Open
Keywords: PET/CT; multiple myeloma; novel radiopharmaceuticals; radiomics; theranostics
(This special issue belongs to the Section Methods and Technologies Development)
The Emerging Role of Multiplexed Imaging for Cancer Diagnosis and Therapy (2nd Edition)
edited by and
submission deadline 31 Jul 2026 | Viewed by 27 | Submission Open
Keywords: multiplexed imaging; cancer diagnosis; molecular imaging; novel contrast agents; targeted radionuclide tracers theragnostics; personalized cancer therapy; therapeutic monitoring; imaging biomarkers; clinical translation
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Perioperative Care and Pain Management in Cancer Patients: From Basic Science to Clinical Practice—2nd Edition
edited by
submission deadline 31 Jul 2026 | Viewed by 10 | Submission Open
Keywords: perioperative care; cancer anesthesia; analgesia; pain management
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Clinical Trials for Hepatobiliary and Pancreatic Cancer Diagnosis and Treatment (2nd Edition)
edited by
submission deadline 31 Jul 2026 | Viewed by 9 | Submission Open
Keywords: biliary cancer; liver cancer; pancreatic cancer; clinical trial; diagnosis; surgery; neoadjuvant therapy; adjuvant therapy; radiotherapy; chemotherapy; targeted therapy; precision medicine; immunotherapy; biliary and duodenal stent; psycho-oncology; palliative and supportive care
(This special issue belongs to the Section Clinical Research of Cancer)
Mechanisms of Therapy Resistance in Cancers—2nd Edition
edited by
submission deadline 31 Jul 2026 | Viewed by 6 | Submission Open
Keywords: ATP-binding cassette transporters; cancer stem cells; extracellular ATP; repair of DNA damage; immunotherapy resistance
(This special issue belongs to the Section Cancer Drug Development)
Circulating Tumor Cells (CTCs) (2nd Edition)
edited by
submission deadline 31 Jul 2026 | Viewed by 4 | Submission Open
Keywords: liquid biopsy; metastatic biomarkers; CTCs isolation technologies; tumor heterogeneity; clinical CTC applications
(This special issue belongs to the Section Tumor Microenvironment)
Rare Cancers, Diagnostic Challenges and Personalized Therapeutic Approaches in the 21st Century (2nd Edition)
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 495 | Submission Open
Keywords: rare cancer; biology; diagnosis; classification; personalized therapeutics; markers
(This special issue belongs to the Section Cancer Therapy)
Advances in Clinical, Diagnostic and Neurosurgical Management in Pediatric Neuro-Oncology
edited by and Michael Levy
submission deadline 20 Aug 2026 | Viewed by 58 | Submission Open
Keywords: neuro-oncology; brain tumors; neuroradiology; proton therapy; pediatric; neurosurgery; treatment; chemotherapy; targeted agents; molecular subtypes; immunotherapy; late effects; radiation therapy
(This special issue belongs to the Section Pediatric Oncology)
Socio-Demographic Factors and Cancer Research: 2nd Edition
edited by and Amanda N. Goldin
submission deadline 20 Aug 2026 | Viewed by 4 | Submission Open
Keywords: socio-economic disparity; cancer delivery; cancer survival; metastatic cancer; culture-specific cancer outcomes; AI; machine learning
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Cancer Stem Cells: The Origin of Tumor Relapse and Metastasis submission deadline 31 Aug 2026 | 1 articles | Viewed by 904 | Submission Open
Keywords: metastasis; cancer stem cell; tumor microenvironment; tumor heterogeneity; plasticity; immune evasion; therapeutic resistance
(This special issue belongs to the Section Molecular Cancer Biology)
Hereditary Cancer: State of the Art
edited by Joanne Ngeow, Jianbang Chiang and
submission deadline 31 Aug 2026 | Viewed by 62 | Submission Open
Keywords: hereditary cancer syndromes; inherited cancers; cancer genetics and genomics; germline variants; surveillance
(This special issue belongs to the Section Cancer Pathophysiology)
Cancer-Therapy-Related Adverse Events (2nd Edition)
edited by and Pauline Funchain
submission deadline 1 Sep 2026 | Viewed by 24 | Submission Open
Keywords: cancer; cancer therapy; toxicities; adverse events
(This special issue belongs to the Section Cancer Therapy)
Novel Advancements in Prostate Cancer Surgery: Indications and Techniques
edited by Valerio Santarelli and
submission deadline 30 Sep 2026 | 1 articles | Viewed by 485 | Submission Open
Keywords: radical prostatectomy; prostate cancer; technology; minimally invasive surgery
(This special issue belongs to the Section Cancer Therapy)
Decision-Making Biomarkers in the Treatment of Hepatocellular Carcinoma
edited by and
submission deadline 30 Sep 2026 | Viewed by 107 | Submission Open
Keywords: hepatocellular carcinoma; borderline resectable; conversion therapy; neoadjuvant therapy; immunotherapy; immune-related adverse event; molecular-targeted agent
(This special issue belongs to the Section Cancer Biomarkers)
The Development of Effective Therapy Targeting the Microenvironment of Cancer (2nd Edition)
edited by and Kanae Taruno
submission deadline 30 Sep 2026 | Viewed by 48 | Submission Open
Keywords: cancer; tumor microenvironment; cancer therapy; cancer cell; animal level
(This special issue belongs to the Section Tumor Microenvironment)
Cancer Immunotherapy-Related Adverse Events and Therapy-Related Accelerated Aging
edited by
submission deadline 30 Sep 2026 | Viewed by 38 | Submission Open
Keywords: immune-related adverse events (irAEs); accelerated aging; immunotherapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Tumor-Initiating Cells in Cancer: Their Interactions with Other Cell Types, and Prospective Applications
edited by
submission deadline 30 Sep 2026 | Viewed by 30 | Submission Open
Keywords: cancer stem cells; cancer stem-like cells; leukemia; chromatin; transcription factors; cellular phenotype; microenvironment; immunity; tumor stroma
(This special issue belongs to the Section Tumor Microenvironment)
Multimodal Artificial Intelligence/Machine Learning Applications in Malignant Tumors: Diagnosis, Prognosis, and Management
edited by and Stefan Haider
submission deadline 30 Sep 2026 | Viewed by 20 | Submission Open
Keywords: machine learning; radiomics; cancer imaging; malignancy; survival
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Omics Data for Cancer Therapies: From Molecular Profiling to Clinical Applications
edited by
submission deadline 31 Oct 2026 | Viewed by 56 | Submission Open
Keywords: multi-omics integration; precision oncology; biomarker discovery; computational oncology; translational cancer research
(This special issue belongs to the Section Cancer Informatics and Big Data)
Oncologic Pathology: Diagnostic Challenges, Molecular Advances, and Clinical Correlations submission deadline 31 Oct 2026 | Viewed by 55 | Submission Open
Keywords: solid neoplasia; predictive and prognostic biomarkers; target therapy; tumor microenvironment; molecular biology
(This special issue belongs to the Section Cancer Pathophysiology)
Molecular Targets and Therapeutic Pathways in Cancer
edited by Ashish H. Shah and Deepa Seetharam
submission deadline 31 Oct 2026 | Viewed by 26 | Submission Open
Keywords: cancer therapeutics; molecular targets; signal transduction pathways; targeted therapy; drug resistance; precision oncology; tumor microenvironment; immunotherapy; kinase inhibitors; translational cancer research
(This special issue belongs to the Section Cancer Drug Development)
New Findings in Targeting Cancer Proteins (Second Edition) submission deadline 30 Nov 2026 | Viewed by 48 | Submission Open
Keywords: monoclonal antibodies; protein target; immunotherapy; signaling blockade; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
Immunotherapy with Checkpoint Inhibitors for Non-Small-Cell Lung Cancer (2nd Edition) submission deadline 30 Dec 2026 | Viewed by 40 | Submission Open
Keywords: immune-checkpoint inhibitors; non-small cell lung cancer; neoadjuvant therapy; adjuvant therapy; primary resistance; acquired; resistance; biomarkers; immune-related adverse events
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
CancersScape: Spatial Biology of the Tumor Ecosystem
edited by and Sammy Ferri-Borgogno
submission deadline 31 Dec 2026 | Viewed by 151 | Submission Open
Keywords: cancer; health; tumor microenvironment; spatial biology; cancer diagnosis; cancer drug discovery; Omics
Cancer Cell Communications, Metastasis and Survival in the Host Microenvironment—2nd Edition
edited by
submission deadline 31 Dec 2026 | Viewed by 22 | Submission Open
Keywords: cancer cells; cancer cell-derived cytokines; host microenvironment; metastasis; gene alteration; signaling pathways; host cells
(This special issue belongs to the Section Tumor Microenvironment)
New Statistical and Machine Learning Methods for Cancer Research
edited by Anjishnu Banerjee
submission deadline 20 May 2027 | Viewed by 31 | Submission Open
Keywords: statistical methods; machine learning; “Omics” research; adaptive clinical trials; drug development; personalized cancer therapies
(This special issue belongs to the Section Cancer Informatics and Big Data)
Cancer Causes and Control submission deadline 1 Dec 2027 | 4 articles | Viewed by 8959 | Submission Open
Keywords: cancer burden; risk factors for cancer; primary cancer prevention; secondary cancer prevention; tertiary cancer prevention; quality of life for people who have cancer; population-based cancer registry
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
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