Special Issues

Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Virus-Associated Head and Neck Cancer submission deadline 21 May 2025 | Viewed by 73 | Submission Open
Keywords: onco-virus; virus-associated cancer; head and neck cancers; diagnosis; pathogenesis; epidemiology; prevalence; treatment; HPV; EBV
(This special issue belongs to the Section Infectious Agents and Cancer)
Recent Updates on Imaging and Staging of Gynecologic Cancers
edited by and Alexander B. Olawaiye
submission deadline 21 May 2025 | Viewed by 37 | Submission Open
Keywords: imaging; surgical staging; molecular prognostic features; mortality; prognosis
(This special issue belongs to the Section Methods and Technologies Development)
The Advance of Biomarker-Driven Targeted Therapies in Cancer
edited by , Qiushi Wang and Ann Bode
submission deadline 30 May 2025 | Viewed by 178 | Submission Open
Keywords: biomarkers; targeted therapies; precision medicine; cancer treatment; molecular profiling; personalized medicine; genomic alterations; therapeutic interventions; tumor microenvironment; immune therapy
(This special issue belongs to the Section Cancer Therapy)
Molecular Insights into Drug Resistance in Cancer
edited by Yang Yuqi
submission deadline 31 May 2025 | 9 articles | Viewed by 10361 | Submission Open
Keywords: drug resistance; cancer treatment; molecular mechanism; chemotherapeutic therapy; small molecules; biologics/large molecules; leukemia; solid tumor
(This special issue belongs to the Section Molecular Cancer Biology)
Novel Experimental Therapeutic Targets and Strategies for Brain Tumors
edited by and
submission deadline 31 May 2025 | 2 articles | Viewed by 4729 | Submission Open
Keywords: brain tumors; glioma; glioblastoma; medulloblastoma; radiotherapy; chemotherapy; immunotherapy; combination therapy; microRNAs; oncogene signaling pathways; epigenetic regulation; metabolic regulation; nanotechnology; drug delivery
(This special issue belongs to the Section Cancer Therapy)
The Neoadjuvant Therapy for Breast Cancer
edited by Marcus Vetter and
submission deadline 31 May 2025 | 1 articles | Viewed by 1071 | Submission Open
Keywords: breast cancer; neoadjuvant treatment; innovative therapy; outcome studies; molecular treatments
(This special issue belongs to the Section Cancer Therapy)
Cell Adhesion in Human Cancer
edited by , Makoto Osanai and
submission deadline 31 May 2025 | 1 articles | Viewed by 904 | Submission Open
Keywords: cell-to-cell adhesion; tight junctions; cytoskeleton; cancer; signal transduction pathways; transcriptional factors; EMT; cell metabolism; mechanical tension; human cells
(This special issue belongs to the Section Molecular Cancer Biology)
Neurosurgical Management of Gliomas
edited by Nicolas Reyns
submission deadline 31 May 2025 | Viewed by 397 | Submission Open
Keywords: neurosurgery; neurological surgery; brain surgery; gliomas
(This special issue belongs to the Section Cancer Therapy)
Contemporary Diagnosis and Management of Prostate Cancer
edited by Thomas Jang
submission deadline 31 May 2025 | Viewed by 253 | Submission Open
Keywords: prostate cancer; diagnosis; management; radical prostatectomy; biomarkers
(This special issue belongs to the Section Cancer Therapy)
The Impact of Community Context and Cancer Disparities
edited by Briseis Aschebrook-Kilfoy and Jiajun Luo
submission deadline 31 May 2025 | Viewed by 123 | Submission Open
Keywords: community; contextual factors; neighborhood; social determinants; networks; social integration; social support; discrimination stressors; engagement; residence
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Navigating the Landscape of Female Cancers: Recent Discoveries and Treatment Trends
edited by and Giacomo Barchiesi
submission deadline 31 May 2025 | Viewed by 99 | Submission Open
Keywords: female malignancies; breast cancer; gynecological cancer; ovarian cancer; endometrial cancer; cervical cancer
(This special issue belongs to the Section Cancer Therapy)
Advances in Vulvar Cancer submission deadline 31 May 2025 | Viewed by 94 | Submission Open
Keywords: vulvar squamous cell carcinoma (VSCC); HPV; p53; molecular characteristics; diagnosis; therapeutic approaches; prognostic biomarkers
(This special issue belongs to the Section Clinical Research of Cancer)
Diagnoses and Treatments of Metastatic Endometrial Cancer
edited by
submission deadline 31 May 2025 | Viewed by 88 | Submission Open
Keywords: endometrial cancer; mesonephric-like adenocarcinoma; pilomatrix-like high-grade endometrioid carcinomas; endometrial carcinosarcomas showing different prognosis based on different epithelial and mesenchymal components; pathologic diagnosis; imaging studies; target therapy; clinical trials
(This special issue belongs to the Section Cancer Therapy)
Oncogenic Driver Mutations and Signaling Pathways in Tumorigenesis and Therapy in Lung Cancer
edited by
submission deadline 31 May 2025 | Viewed by 78 | Submission Open
Keywords: lung cancer; oncogenic driver mutations; signaling pathways; tumorigenesis; therapy; precision medicine; targeted therapy; biomarkers; resistance mechanisms; therapeutic strategies
(This special issue belongs to the Section Tumor Microenvironment)
Oncology: State-of-the-Art Research in Austria
edited by and Mir Alireza Hoda
submission deadline 31 May 2025 | Viewed by 66 | Submission Open
Keywords: oncology; cancer; research; tumor; Austria
(This special issue belongs to the Section Cancer Therapy)
Updates on Breast Cancer Screening
edited by Jacopo Nori
submission deadline 31 May 2025 | Viewed by 62 | Submission Open
Keywords: breast cancer screening; digital breast tomosynthesis (DBT); MRI; genetic screening; risk assessment models; artificial intelligence (AI); contrast-enhanced mammography; dense breast tissue; screening guidelines; overdiagnosis and overtreatment
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Therapeutic Optimization of Anti-Tumor Drugs Based on Pharmacokinetics
edited by Paula Fresco and Joaquim António Faria Monteiro
submission deadline 31 May 2025 | Viewed by 46 | Submission Open
Keywords: anti-cancer drugs; pharmacokinetics; therapeutic drug monitoring; cancer; populational pharmacokinetics models
(This special issue belongs to the Section Cancer Drug Development)
Imaging-Guided Interventional Cancer Combination Immunotherapy
edited by
submission deadline 31 May 2025 | Viewed by 8 | Submission Open
Keywords: image-guided cancer immunotherapy; image-guided combination therapies; local ablation; targeted immunotherapy; the assessment of therapeutic response
(This special issue belongs to the Section Methods and Technologies Development)
Advancements in Bladder Cancer Therapy
edited by
submission deadline 31 May 2025 | Submission Open
Keywords: diagnostic; molecular markers; treatment; instillation therapy; systemic therapy; bladder sparring protocols
(This special issue belongs to the Section Cancer Therapy)
The Role of Medical Imaging in Gynecological Cancer
edited by Emma R. Allanson and Ming Yin Lin
submission deadline 1 Jun 2025 | 3 articles | Viewed by 3393 | Submission Open
Keywords: cervical cancer; endometrial cancer; ovarian cancer; staging; ultrasound; MRI; PET-CT; radiotherapy; image-guided brachytherapy
(This special issue belongs to the Section Methods and Technologies Development)
Molecular Diversity of Gliomas: Epidemiology, Pathology and Genetic/Epigenetic Heterogeneity submission deadline 1 Jun 2025 | 1 articles | Viewed by 1752 | Submission Open
Keywords: glioma molecular heterogeneity; glioblastoma demographics; glioma spatiotemporal evolution; glioma genomics; glioma epigenomics; glioma pathology; animal and organoid models of glioma heterogeneity
(This special issue belongs to the Section Cancer Pathophysiology)
New Developments in Breast Cancer Surgery, Risk, and Related Quality of Life
edited by Vesna Bjelic-Radisic, and Constanze Elfgen
submission deadline 1 Jun 2025 | Viewed by 34 | Submission Open
Keywords: oncoplastic breast surgery; breast reconstruction; quality of life
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Bone and Soft Tissue Tumors: Molecular Mechanisms, Clinical Practice, and Emerging Therapeutics
edited by Toshihiro Akisue, and Toru Akiyama
submission deadline 15 Jun 2025 | 4 articles | Viewed by 4680 | Submission Open
Keywords: bone and soft tissue sarcoma; imaging modality; surgical treatment; systemic treatment; molecular-targeted treatment; biomarkers; prognostic parameters
(This special issue belongs to the Section Clinical Research of Cancer)
Mathematical Oncology: Using Mathematics to Enable Cancer Discoveries submission deadline 15 Jun 2025 | Viewed by 934 | Submission Open
Keywords: mathematical oncology; computational biology; mathematical modeling; computational oncology; data-driven modeling; physical oncology
(This special issue belongs to the Section Methods and Technologies Development)
Advances in B-cell Lymphoma: From Diagnostics to Cure
edited by and Megan E. Melody
submission deadline 15 Jun 2025 | Viewed by 139 | Submission Open
Keywords: B-cell lymphoma; treatment; molecular profiling; immunotherapies; cellular therapies
(This special issue belongs to the Section Cancer Therapy)
Perioperative Care and Pain Management in Cancer Patients: From Basic Science to Clinical Practice
edited by and
submission deadline 20 Jun 2025 | 2 articles | Viewed by 5798 | Submission Open
Keywords: cancer anesthesia; palliative care; chronic cancer pain; oncologic surgery; mini-invasive techniques; nanomedicine; cancer biomarkers; chronic interventional pain; opioids; regional anesthesia; opioid-free anesthesia
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
The Advance of Pencil Beam Scanning Proton Beam Therapy in Cancers
edited by , Richard A. Amos and Heng Li
submission deadline 20 Jun 2025 | 3 articles | Viewed by 4169 | Submission Open
Keywords: proton therapy; pencil beam scanning; robustness; adaptive radiotherapy; imaging guidance; radiobiological model; FLASH radiotherapy; spatially fractionated radiotherapy (SFRT); proton arc
(This special issue belongs to the Section Cancer Therapy)
Application of Artificial Intelligence in Radiation Oncology
edited by Xiaofeng Yang, Lei Qiu and Tonghe Wang
submission deadline 20 Jun 2025 | Viewed by 70 | Submission Open
Keywords: artificial intelligence; radiation oncology; medical physics; cancer biology; medical imaging; segmentation; treatment planning; adaptive radiation therapy; predictive modeling; patient safety; clinical workflows; personalized treatment; biomarkers
(This special issue belongs to the Section Methods and Technologies Development)
The Epidemiological Studies of Gynecological Cancers
edited by Nithya Ratnavelu and Ioannis Biliatis
submission deadline 20 Jun 2025 | Submission Open
Keywords: ovarian cancer; endometrial cancer; cervical cancer; vulva cancer; vaginal cancer; gynecological cancer
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Molecular and Genetic Biomarkers in Head and Neck Squamous Cell Carcinoma
edited by and Michal Masternak
submission deadline 24 Jun 2025 | Viewed by 36 | Submission Open
Keywords: head and neck squamous cell carcinoma (HNSCC); molecular biomarkers; genetic biomarkers; multi-omics approaches; HNSCC carcinogenesis; prognostic biomarkers; translational medicine; molecular pathology
(This special issue belongs to the Section Molecular Cancer Biology)
Looking for New Biochemical Mechanisms in Cancer: The New Dawn in the Omics Sciences
edited by , Marco Bocchetti and
submission deadline 26 Jun 2025 | Viewed by 382 | Submission Open
Keywords: multi-omics; machine learning; sequencing; signal transduction; molecular mechanisms; circulating biomarker; cancer
(This special issue belongs to the Section Molecular Cancer Biology)
Advances in the Prevention and Treatment of Liver Cancer
edited by Ewa Janczewska
submission deadline 30 Jun 2025 | 5 articles | Viewed by 5326 | Submission Open
Keywords: new screening techniques; enhanced imaging; biomarker tests; radiofrequency ablation; transarterial chemoembolization
(This special issue belongs to the Section Cancer Therapy)
New Challenges for Gastric Cancer—Gut Microbiota, Post-eradication and Chemotherapy
edited by Kazunari Murakami and
submission deadline 30 Jun 2025 | 2 articles | Viewed by 1895 | Submission Open
Keywords: gastric cancer; microbiota; Helicobacter pylori; after Helicobacter pylori eradication therapy; chemotherapy; immune checkpoint inhibitor
(This special issue belongs to the Section Cancer Therapy)
Clinical Diagnosis, Treatment, and Prognosis of Uveal Melanoma
edited by Josep Maria Caminal Mitjana
submission deadline 30 Jun 2025 | 2 articles | Viewed by 964 | Submission Open
Keywords: uveal melanoma; choroidal melanoma; gene expression profiling; immunotherapy; metastasis; radiotherapy; liquid biopsy; circulating tumor cells; brachytherapy; next-generation sequencing; proton therapy
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Abdominal Surgical Oncology and Intraperitoneal Therapies submission deadline 30 Jun 2025 | 1 articles | Viewed by 616 | Submission Open
Keywords: abdominal oncologic surgery; minimally invasive techniques; laparoscopy; robotics; fluorescence; artificial intelligence; augmented vision; peritoneal carcinomatosis; intraperitoneal chemotherapy; liquid biopsy
(This special issue belongs to the Section Cancer Therapy)
Educating Recent Updates on Metastatic Non-small Cell Lung Cancer submission deadline 30 Jun 2025 | Viewed by 416 | Submission Open
Keywords: non-small cell lung cancer; lung adenocarcinoma; lung squamous cell carcinoma; tumor microenvironment (TME); epithelial to mesenchymal transition (EMT); cancer metastasis; desmoplasia; tumor matrix biology; epigenetic modulations leading cancer metastasis; post-translational modifications (PTMs); immune evasion
(This special issue belongs to the Section Cancer Metastasis)
Exercise Interventions for People Living with Cancer: Advances in Knowledge and Implementation
edited by and Chris Swain
submission deadline 30 Jun 2025 | Viewed by 209 | Submission Open
Keywords: cancer; survivorship; exercise; physical activity; implementation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Cervical Cancer: Clinical Feature, Trial and Management
edited by , and Carlo Saccardi
submission deadline 30 Jun 2025 | Viewed by 157 | Submission Open
Keywords: cervical cancer; diagnosis; minimally invasive surgery; laparoscopy; locally advanced disease; management; treatment; adjuvant chemotherapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Epigenetic Regulation in Hematologic Malignancies
edited by Travis S. Johnson
submission deadline 30 Jun 2025 | Viewed by 146 | Submission Open
Keywords: epigenetic regulation; hematologic malignancies; DNA methylation; non-coding RNA; therapeutic targeting
(This special issue belongs to the Section Tumor Microenvironment)
Oncology: State-of-the-Art Research in Canada
edited by
submission deadline 30 Jun 2025 | Viewed by 135 | Submission Open
Keywords: cancer research; tumor; oncology; Canada
Cancer Biomarkers—Detection and Evaluation of Response to Therapy submission deadline 30 Jun 2025 | Viewed by 124 | Submission Open
Keywords: biomarkers; cancer detection; biomarkers of response to antineoplastic drugs; biomarkers of resistance to chemotherapy; biomarkers for targeted therapies
(This special issue belongs to the Section Cancer Biomarkers)
Novel Advances in the Molecular Understanding of Myeloproliferative Neoplasms (MPNs)
edited by Wei Chen, Fei Li and
submission deadline 30 Jun 2025 | Viewed by 117 | Submission Open
Keywords: MPNs; ET; PV; PMF; post-PV-MF; post-ET-MF; MDS/MPN; JAK2
(This special issue belongs to the Section Molecular Cancer Biology)
Oncology: State-of-the-Art Research in The Netherlands
edited by
submission deadline 30 Jun 2025 | Viewed by 114 | Submission Open
Keywords: cancer research; oncology; The Netherlands; cutting-edge; translational studies
Cardio-Oncology: An Emerging Paradigm in Modern Medicine: 2nd Edition
edited by Rohit Moudgil
submission deadline 30 Jun 2025 | Viewed by 107 | Submission Open
Keywords: cardio-oncology; CTRCD; arrhythmias; anthracyclines; anti-her2 therapies; immune checkpoint inhibitors; artificial intelligence; guidelines; emerging research
(This special issue belongs to the Section Cancer Therapy)
Multidisciplinary Management of Rectal Cancer
edited by Hiroshi Doi
submission deadline 30 Jun 2025 | Viewed by 81 | Submission Open
Keywords: rectal cancer; neoadjuvant radiotherapy; preoperative radiotherapy; total neoadjuvant therapy; watch-and-wait strategy; stereotactic body radiotherapy; particle therapy; therapeutic response assessment; biomarkers; radiomics
(This special issue belongs to the Section Cancer Therapy)
How Ubiquitin and Ubiquitination Affect Cancer Progression
edited by Anna A. Sablina
submission deadline 30 Jun 2025 | Viewed by 57 | Submission Open
Keywords: cancer ubiquitinome; ubiquitin ligases in cancer; deubiquitinating enzymes in cancer; proteasome pathway; protein stability; non-degrative ubiquitination; PROTACs for cancer treatment
(This special issue belongs to the Section Molecular Cancer Biology)
Survivorship and Quality of Life in Endometrial Cancer
edited by George Koukourakis, , Georgios Angelopoulos and Anthi Miliadou
submission deadline 30 Jun 2025 | Viewed by 51 | Submission Open
Keywords: endometrial cancer; quality of life; survivorship
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Diagnosis, Staging, and Management for Gynecologic Oncology
edited by
submission deadline 30 Jun 2025 | Viewed by 35 | Submission Open
Keywords: gynecologic oncology; cancer biology; HPV infection; molecular risk factors; translational medicine; cancer staging systems; radiation therapy; brachytherapy; radioresistance
(This special issue belongs to the Section Cancer Therapy)
Lymph Node Detection in Gynecological Cancers
edited by Roberto Berretta
submission deadline 30 Jun 2025 | Viewed by 30 | Submission Open
Keywords: sentinel node; endometrial cancer; cervical cancer; vulvar cancer; nodal staging; ultra-staging; isolated tumor cells; micrometastasis; nodal staging
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advance in Treatment of Uveal Melanoma submission deadline 30 Jun 2025 | Viewed by 24 | Submission Open
Keywords: uveal melanoma; distant metastases; treatment modalities
(This special issue belongs to the Section Cancer Therapy)
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