Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Role of IgE and IgG Antibodies in Allergic Reactions: Cellular Mechanisms and Biological Implications submission deadline 31 Dec 2024 | Viewed by 267 | Submission Open
Keywords: IgE; IgG; allergy; inflammation; glycosylation; immunotherapy; autoantibodies; Fc receptors; soluble receptors
(This special issue belongs to the Section Cellular Immunology)
Cellular and Molecular Mechanisms in Immune Regulation
edited by Fábio Rinaldo Santori and Natalia B. Ivanova
submission deadline 31 Dec 2024 | Viewed by 260 | Submission Open
Keywords: innate immunity; dendritic cells; macrophages; T cells; B cells; cytokines; immunotherapy
(This special issue belongs to the Section Cellular Immunology)
Unlocking the Gates: Multidrug Resistance Proteins—Mechanisms and Therapeutic Strategies
edited by , Angela Cozma and Cezar Login
submission deadline 31 Dec 2024 | Viewed by 248 | Submission Open
Keywords: multidrug resistance; ABC transporters; therapeutic resistance; drug efflux mechanisms; chemotherapy challenges; targeted therapy strategies
(This special issue belongs to the Section Cellular Pathology)
Molecular Genetics of Eye Development and Myopia
edited by Joanna Swierkowska-Janc, and
submission deadline 31 Dec 2024 | Viewed by 247 | Submission Open
Keywords: myopia; high myopia; refractive error; genetics of eye disorders; candidate genes; animal models; epigenetics; transcriptomics; retina; cell lines
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
CDKs and CDK-Interacting Proteins/Kinase-Inhibitory Proteins in Human Health and Disease submission deadline 31 Dec 2024 | Viewed by 219 | Submission Open
Keywords: Cell cycle; CDKs; cyclins; CIP/Kip proteins; INK4 family; p53; transcriptional regulation; DNA damage; cytoskeleton; metabolism; senescence; cell death; cell commitment and  differentiation; stem cell; tissue regeneration; embryogenesis; development; growth-related diseases; cancer; sensitivity/resistance to therapy; target therapy
(This special issue belongs to the Section Cellular Pathology)
Graft versus Host Disease (GVHD) after Hematopoietic Cell Transplantation
edited by Senthilnathan Palaniyandi
submission deadline 31 Dec 2024 | Viewed by 217 | Submission Open
Keywords: acute graft versus host disease; chronic graft versus host disease; hematopoietic cell transplantation; transplant immunology
(This special issue belongs to the Section Cellular Immunology)
Lipids, Lipoproteins and Lipid-Targeting Therapies in the Regulation of Immune Function and Inflammation submission deadline 31 Dec 2024 | Viewed by 213 | Submission Open
Keywords: lipids; lipoproteins; HDL; lipid-targeting therapies; immune function; immune cell activation and differentiation; immune inflammation; chronic disease; cardiometabolic disease; infectious disease; proteomics; lipidomics; lifestyle interventions; emerging methods
(This special issue belongs to the Section Cellular Immunology)
Neuroendocrine Regulation of Metabolic Balance
edited by Chunmei Wang
submission deadline 31 Dec 2024 | Viewed by 201 | Submission Open
Keywords: neuroendocrine system; glucose balance; energy balance
(This special issue belongs to the Section Cells of the Nervous System)
Identifying Novel Targets and Mechanisms That Drive Pathogenic Fibrosis and Cancer
edited by Gerlinde Wernig and
submission deadline 31 Dec 2024 | Viewed by 193 | Submission Open
Keywords: fibrosis; cancer; extracellular matrix; inflammation; epithelial-to-mesenchymal transition; oxidative stress; cellular senescence; hippo pathway; fibroblast activation
(This special issue belongs to the Section Cellular Pathology)
New Molecular and Computational Approaches to Study Immune and Metabolic Interactions in Cancer Biology
edited by Federica Mornata, Luca De Feo, Rebecca Polidori and
submission deadline 31 Dec 2024 | Viewed by 170 | Submission Open
Keywords: solid and liquid cancer; cancer metabolism; tumor microenvironment; digital pathology; immunoncology
(This special issue belongs to the Section Cell Methods)
Neurodevelopmental Disabilities (NDDs): From Cellular and Molecular Mechanisms to Innovative Therapy
edited by and Denise Drongitis
submission deadline 31 Dec 2024 | Viewed by 140 | Submission Open
Keywords: neurodevelopmental disorders; cellular mechanisms; molecular mechanisms; genetic factors; brain plasticity; innovative therapies; KDM5C
(This special issue belongs to the Section Cellular Pathology)
Aging and Metabolic Diseases
edited by
submission deadline 31 Dec 2024 | Viewed by 132 | Submission Open
Keywords: aging; insulin resistance; diabetes; obesity; mitochondrial dysfunction; beta-galactosidase; senescent-associated secretory phenotype; pancreatic beta cells
(This special issue belongs to the Section Cellular Aging)
Advances in the Study of Neuroinflammation submission deadline 31 Dec 2024 | Viewed by 132 | Submission Open
Keywords: neuroinflammation; neurodegenerative disease; bacterial meningitis; glia cell; microglial cell; macrophage; astrocyte; blood– brain barrier; meninges; meningeal immunity; meningeal lymphatic vessels
(This special issue belongs to the Section Cells of the Nervous System)
Molecular Mechanisms of Neuropathic Pain submission deadline 31 Dec 2024 | Viewed by 129 | Submission Open
Keywords: neuropathic pain; nociplastic pain; fibromyalgia; brain-immune connection; sexual dimorphism; glial cells; lysophosphatidic acid
(This special issue belongs to the Section Cells of the Nervous System)
T Cells in Inflammation and Cancer
edited by
submission deadline 31 Dec 2024 | Viewed by 124 | Submission Open
Keywords: T cell; immunity; disease; infection; cancer; inflammation; pathology; immunotherapy
(This special issue belongs to the Section Cellular Immunology)
Advances in Intestinal Epithelial Plasticity and Regeneration
edited by
submission deadline 31 Dec 2024 | Viewed by 121 | Submission Open
Keywords: intestinal epithelium; epithelial plasticity; stem cells; tissue repair; self-renewal; regeneration
Ageing and Neurodegenerative Diseases, Second Edition
edited by Feng Wang and
submission deadline 31 Dec 2024 | Viewed by 117 | Submission Open
Keywords: ageing; miRNAs; lncRNA; circRNAs; diabetes; neurodegenerative disease; insulin signaling
(This special issue belongs to the Section Cellular Pathology)
The Potential of Induced Pluripotent Stem Cells
edited by Yun Chang
submission deadline 31 Dec 2024 | Viewed by 109 | Submission Open
Keywords: pluripotent stem cells; reprogramming; engineering; regenerative medicine; differentiation; therapeutic applications; biomaterials
(This special issue belongs to the Section Stem Cells)
Key Cells in the Pathogenesis, Diagnosis and Treatment of Allergies
edited by
submission deadline 31 Dec 2024 | Viewed by 99 | Submission Open
Keywords: allergy; immunoglobulin E; allergen; immune cell; diagnosis; pathogenesis; therapy; prevention
(This special issue belongs to the Section Cellular Immunology)
Cell Therapies in Cancer Treatment
edited by
submission deadline 31 Dec 2024 | Viewed by 96 | Submission Open
Keywords: cellular therapies; cancer; immune
Extracellular Vesicles Based Drug Delivery submission deadline 31 Dec 2024 | Viewed by 91 | Submission Open
Keywords: EV engineering; targeting; therapy; natural carrier; exosomes
Adaptation of Oral Tissue and Bone Remodeling to Systemic Imbalances
edited by Collin Jacobs, Ulrike Schulze-Späte and
submission deadline 31 Dec 2024 | Viewed by 89 | Submission Open
Keywords: oral health; oral disease; bone remodeling; tissue remodeling; systemic imbalances; metabolic shift; periodontal disease; non-communicable diseases; obesity; diabetes; aging; osteoporosis; drug consumption; mental health
Heme Biology in Health and Disease
edited by Pranjal Biswas and Yue Dai
submission deadline 31 Dec 2024 | Viewed by 85 | Submission Open
Keywords: heme; hemeproteins; heme synthesis; heme breakdown; iron-protoporphyrin IX
(This special issue belongs to the Section Cells of the Cardiovascular System)
The Role of T Cells in Type 1 Diabetes submission deadline 31 Dec 2024 | Viewed by 82 | Submission Open
Keywords: T cells; inflammation; T cell receptor; type 1 diabetes
(This special issue belongs to the Section Cellular Immunology)
The Role of T-Cells in Lymphomas and Leukemias
edited by
submission deadline 31 Dec 2024 | Viewed by 69 | Submission Open
Keywords: T cells; regulatory T cells; leukemia; lymphoma; hematological malignancies; chimeric antigen receptor; CAR T cells; tumor microenvironment; tumor-infiltrating T cells; TCR; adoptive T cell therapy; TCR-engineered T cells
(This special issue belongs to the Section Cellular Immunology)
Cell and Immune Therapeutics for Gliomas
edited by and
submission deadline 10 Jan 2025 | 1 articles | Viewed by 5023 | Submission Open
Keywords: immune modulation; T-cell activation; tumour-associated macrophages; tumour microenvironment; stem cells
(This special issue belongs to the Section Cell Microenvironment)
Kidney Disease Models, Cellular Mechanism and Potential Treatment
edited by
submission deadline 10 Jan 2025 | Viewed by 273 | Submission Open
Keywords: kidney disease; signaling pathways; therapy; biomarker; prevention
(This special issue belongs to the Section Tissues and Organs)
Cell Death Mechanisms and Therapeutic Opportunities in Glioblastoma
edited by
submission deadline 15 Jan 2025 | 18 articles | Viewed by 38665 | Submission Open
Keywords: apoptosis; autophagy; cell death mechanisms; cell signaling; glioblastoma; therapeutic opportunities
(This special issue belongs to the Section Cells of the Nervous System)
Cellular and Clinical Mechanisms of Obesity and Diabetes and Their Complications submission deadline 15 Jan 2025 | 1 articles | Viewed by 1623 | Submission Open
Keywords: obesity; type 1 diabetes; type 2 diabetes; metabolic disorders; complications; signaling pathways; pathophysiology; insulin; β -cell
(This special issue belongs to the Section Cellular Pathology)
Emerging Targets and Therapeutic Potential Drugs in Tumor Progression and Therapeutic Resistance
edited by , and Yuancheng Li
submission deadline 15 Jan 2025 | 1 articles | Viewed by 1287 | Submission Open
Keywords: cancer; tumor progression; therapeutic resistance; molecular targets; tumor microenvironment; innovative therapies; targeted drug delivery; natural product
(This special issue belongs to the Section Cell Microenvironment)
Role of Autophagy in Plant Cells
edited by
submission deadline 15 Jan 2025 | 1 articles | Viewed by 1129 | Submission Open
Keywords: autophagy; endoplasmic reticulum; TOR; vacuoles; lysosomes; mitochondria; plastids
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Multifaceted Roles of Mesenchymal Stem Cells in Health and Disease
edited by and Bartłomiej Łukaszuk
submission deadline 15 Jan 2025 | 1 articles | Viewed by 826 | Submission Open
Keywords: diabetes mellitus; dyslipidemia; insulin resistance; metabolic syndrome; mesenchymal stem cells; obesity
(This special issue belongs to the Section Stem Cells)
Molecular and Cellular Research on Spinal Cord Injury submission deadline 15 Jan 2025 | 1 articles | Viewed by 774 | Submission Open
Keywords: spinal cord injury; growth inhibitory factors; axonal regeneration; neuroprotection; combined therapies; cell trasnplants; regenerative medicine; inhibition scar formation; extracellular matrix molecules
(This special issue belongs to the Section Cellular Pathology)
Hedgehog Signaling: Advances in Development and Cancer—Second Edition
edited by
submission deadline 15 Jan 2025 | Viewed by 135 | Submission Open
Keywords: hedgehog signaling; hh gene; smoothened (SMO)
The Role of Microglia in Neurodegenerative Diseases and Neuroinflammation
edited by
submission deadline 15 Jan 2025 | Viewed by 115 | Submission Open
Keywords: microglia; central nervous system; neurodegenerative diseases; neurodegeneration; Alzheimer’ s disease (AD); Parkinson’ s disease (PD)
(This special issue belongs to the Section Cellular Aging)
Development and Functions of Novel NK Cell Subsets submission deadline 15 Jan 2025 | Viewed by 108 | Submission Open
Keywords: NK cells; subsets of NK; tissue-resident NK; NK subsets within TME; adaptive NK; memory NK; regulatory NK
(This special issue belongs to the Section Cellular Immunology)
Proteomic Applications in Ageing and Neurodegenerative Conditions submission deadline 20 Jan 2025 | 4 articles | Viewed by 12775 | Submission Open
(This special issue belongs to the Section Cell Methods)
Downstream Pathways in Lysosomal Disorders from Basic Science to Clinical Contexts
edited by
submission deadline 20 Jan 2025 | 2 articles | Viewed by 2473 | Submission Open
Keywords: lysosomal storage diseases; omics; autophagy; mitochondria; advance therapy; biomarkers; precision medicine; genetic diseases; epigenetics; neurodegeneration
(This special issue belongs to the Section Cells of the Nervous System)
Antiphospholipid Syndrome: Molecular Mechanisms and Novel Therapies
edited by and Simona Truglia
submission deadline 20 Jan 2025 | Viewed by 372 | Submission Open
Keywords: antiphospholipid syndrome; pathophysiology; management; treatment; antiphospholipid antibodies; molecular mechanisms; new biomarkers; diagnostic tests
(This special issue belongs to the Section Cellular Pathology)
Regulation of Fibroblasts and Fibrosis in Cardiovascular Disease
edited by
submission deadline 20 Jan 2025 | Viewed by 185 | Submission Open
Keywords: fibrosis; fibroblasts; cardiovascular; inflammation; extracellular matrix; collagen
(This special issue belongs to the Section Cells of the Cardiovascular System)
Metallodrugs against Cancer Cells: Mechanisms of Action and Molecular Targets
edited by and Elisa Abás
submission deadline 20 Jan 2025 | Viewed by 170 | Submission Open
Keywords: cell death; cytotoxicity; molecular mechanism; cell imaging; theragnostic; photodynamic therapy; chemotherapy; gene expression; drug uptake; SAR studies
(This special issue belongs to the Section Cellular Pathology)
Diagnostic, Prognostic and Therapeutic Biomarkers Related to Civilization Diseases: Molecular Aspects and State of the Art—Second Edition submission deadline 20 Jan 2025 | Viewed by 83 | Submission Open
Keywords: pathomechanisms of civilization diseases; risk factors; assessment of therapeutic efficacy; monitored therapy; prognostic markers; anti-inflammatory-inflammatory imbalance; antioxidant-prooxidant imbalance
Signaling Pathways in Endometrial Cancer Cells
edited by
submission deadline 20 Jan 2025 | Viewed by 75 | Submission Open
Keywords: endometrial cancer; cellular signaling; cell metabolism; DNA damage repair pathway; the PI3K/AKT/mTOR pathway; the RAS/MAPK pathway; molecular classification
(This special issue belongs to the Section Cell Signaling)
Adipose-Derived Stem Cells: Current Applications and Future Directions
edited by
submission deadline 20 Jan 2025 | Viewed by 66 | Submission Open
Keywords: cell therapy; regenerative medicine; adipose-derived stem cells (ADSCs); exosome; cytokine
(This special issue belongs to the Section Stem Cells)
Advances and Breakthroughs in Stem Cell Research submission deadline 25 Jan 2025 | 1 articles | Viewed by 2145 | Submission Open
Keywords: stem cell; induced pluripotent stem cell; iPSC; hematopoietic stem cell
(This special issue belongs to the Section Stem Cells)
Dental Pulp Stem Cells in Human Disease
edited by Esther Wolfs, Tim Vangansewinkel and
submission deadline 25 Jan 2025 | 1 articles | Viewed by 1257 | Submission Open
Keywords: dental pulp stem cells; disease; regenerative medicine; disease modeling
(This special issue belongs to the Section Stem Cells)
New Insights into Adipose-Derived Stem Cells (ADSCs)
edited by , and William D’Angelo
submission deadline 30 Jan 2025 | 2 articles | Viewed by 5289 | Submission Open
Keywords: adipose-derived stem cells; immunomodulation; exosomes; cell therapy; clinical translation
(This special issue belongs to the Section Stem Cells)
The Cell Biology of Heart Disease
edited by Rajeshwary Ghosh and
submission deadline 30 Jan 2025 | Viewed by 280 | Submission Open
Keywords: cardiomyopathy; endothelial dysfunction; cellular senescence; fibrosis; myocardial infarction; inflammation; mitochondrial dysfunction; CAD; arrhythmia; heart failure
(This special issue belongs to the Section Cells of the Cardiovascular System)
Signaling in Cancer Stem Cells
edited by Upasana Ray
submission deadline 30 Jan 2025 | Viewed by 203 | Submission Open
Keywords: cancer stem cells (CSCs); stem cells signaling pathways; cancer progression and metastasis; therapeutic resistance; targeting cancer stem cells signaling; cancer heterogeneity; targeted therapy for CSCs; identifying biomarkers for CSCs
(This special issue belongs to the Section Stem Cells)
Advances in Scanning Probe Microscopy in Cell Biology submission deadline 31 Jan 2025 | 12 articles | Viewed by 20262 | Submission Open
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