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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular-Scale Design and Applications of Food Packaging: Eco-Friendly Materials and Technologies

edited by

Xi Yu

and

Tian Zhong

submission deadline 20 Jun 2026 | Viewed by 592 | Submission Open

Keywords: sustainable packaging; biodegradable materials; smart packaging; active packaging; food safety; environmental impact

(This special issue belongs to the Section Materials Science)

Molecular and Cellular Aspects of Autoimmune and Inflammatory Rheumatic Diseases: Second Edition

edited by Marzena Helena Olesińska and Magdalena Szmyrka

submission deadline 20 Jun 2026 | Viewed by 548 | Submission Open

Keywords: autoimmune rheumatic diseases; inflammatory rheumatic diseases; arthritis; connective tissue diseases

(This special issue belongs to the Section Molecular Immunology)

Allosteric Modulation of Kinases in Cancer Therapeutic Strategies and Challenges

edited by

Nidhi Joshi

submission deadline 20 Jun 2026 | Viewed by 527 | Submission Open

Keywords: kinase signaling; allosteric modulators; cancer therapy; drug resistance; molecular mechanisms; protein– protein interactions; targeted therapy; conformational changes; ATP-competitive inhibitors; drug design

(This special issue belongs to the Section Molecular Biology)

Metabolic Reprogramming in Health and Aging-Related Diseases

edited by

Hung-Yao Ho

submission deadline 20 Jun 2026 | Viewed by 513 | Submission Open

Keywords: aging; degenerative diseases; lifestyle intervention; metabolic reprogramming; metabolic syndromes; metabolome; metabolomics; neurodegenerative diseases; omics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advanced Research on the Major Histocompatibility Complex (MHC): From Bench to Bedside

edited by Antonio Arnaiz-Villena

submission deadline 20 Jun 2026 | Viewed by 495 | Submission Open

Keywords: HLA; immunology; HLA genetics and pharmacogenetics; immune and other functions of the MHC; classical and nonclassical MHC class I HLA genes; HLA-G; HLA-E; HLA-F; MHC evolution; complement; autoimmunity; immunodeficiency; cancer; HIV

(This special issue belongs to the Section Molecular Immunology)

Molecular Advances and Insights into Liver Diseases: Second Edition

edited by

Jacek Baj

submission deadline 20 Jun 2026 | Viewed by 488 | Submission Open

Keywords: liver; hepatocellular carcinoma; cancer; hepatitis cirrhosis; encephalopathy; non-alcoholic fatty liver disease; autoimmune diseases; Wilson’ s disease; fatty liver disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into the Pathophysiology of Placenta Accreta Spectrum

edited by Jessian L. Munoz

submission deadline 20 Jun 2026 | Viewed by 473 | Submission Open

Keywords: placenta accreta; invasive placenta; trophoblasts; placenta; high-risk pregnancy; placenta previa; in vitro fertilization; biomarkers; multi-omics research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research Progress on Photosensitizers and Photodynamic Therapy

edited by

Michal Heger

submission deadline 20 Jun 2026 | Viewed by 466 | Submission Open

Keywords: photodynamic therapy; photosensitizers; tumor microenvironment; nanotechnology; immunotherapy; targeted drug delivery; reactive oxygen species; hypoxia; combination therapy; molecular mechanisms

(This special issue belongs to the Section Biochemistry)

Valorization of Lignocellulosic Biomass: 2nd Edition

edited by

Haishun Du

submission deadline 20 Jun 2026 | Viewed by 463 | Submission Open

Keywords: lignocellulosic biomass; biorefinery; biomass conversion; bioenergy; biofuels; bioproducts; platform chemicals; cellulose nanomaterials; lignin nanoparticles; functional materials

(This special issue belongs to the Section Materials Science)

Unravelling Molecular Pathways in Ocular Disease and Degeneration

edited by

Zala Lužnik Marzidovšek

submission deadline 20 Jun 2026 | 1 articles | Viewed by 436 | Submission Open

Keywords: molecular mechanisms; ocular disease; biomarkers; therapeutic targets; regenerative; gene therapies; corneal degeneration; retinal degeneration; optic nerve pathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Urothelial Cancer: From Translational Medicine to Recent Innovations in Therapeutic Management

edited by Alessio Bruni

submission deadline 20 Jun 2026 | Viewed by 432 | Submission Open

Keywords: urothelial cancer; bladder cancer; radiation therapy; trimodality approach; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Genomics and Epigenetics of Stem Cell: An Update

edited by

Vikas Malik

submission deadline 20 Jun 2026 | Viewed by 421 | Submission Open

Keywords: stem cells; epigenetics; genomics; cell fate; self-renewal; differentiation; regenerative medicine; transcription factors

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advanced Research in Alzheimer’s Disease: From Pathology to Therapy

edited by Sofía Yolanda Díaz Miranda

submission deadline 20 Jun 2026 | 1 articles | Viewed by 420 | Submission Open

Keywords: multifunctional compounds in Alzheimer’ s disease therapy; translational medicine in Alzheimer's disease; novel drug candidates for Alzheimer's disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Sphingolipids in Infections, Disorders and Diseases

edited by Elita Avota

submission deadline 20 Jun 2026 | Viewed by 402 | Submission Open

Keywords: sphingolipids; sphingolipid biosynthesis; sphingolipidoses; metabolic disorders; infections; lipidomics; sphingolipid targeting drugs

(This special issue belongs to the Section Biochemistry)

Recent Advances in Metabolism of Alzheimer’s Disease

edited by

Rebecca Piccarducci

and Maria Letizia Trincavelli

submission deadline 20 Jun 2026 | Viewed by 393 | Submission Open

Keywords: Alzheimer’ s disease; brain metabolism; insulin resistance; lipid metabolism; APOE ε 4; metabolic targets; insulin-sensitizing drugs; lifestyle and metabolic interventions

(This special issue belongs to the Section Molecular Neurobiology)

Synthesis, Modification, and Functional Characterization of Advanced Biomaterials for Bone Tissue Engineering

edited by

Elisa Boanini

submission deadline 20 Jun 2026 | Viewed by 386 | Submission Open

Keywords: material functionalization; bioactive materials; antimicrobial; antibiofilm; coatings; scaffolds; bone cements; metal nanoparticles; controlled release; biocompatibility

(This special issue belongs to the Section Materials Science)

Immunology and Immunotherapy for Head and Neck Cancer

edited by

Aurora Mirabile

submission deadline 20 Jun 2026 | Viewed by 382 | Submission Open

Keywords: immunotherapy; head and neck cancer; toxicity management; immune system; nutrition; immune therapy and organ failure; mechanisms of immunotherapy resistance

(This special issue belongs to the Section Molecular Immunology)

Molecular Interplay Between Aging, Dementia and Renal Function: Mechanisms, Biomarkers and Therapeutic Targets

edited by

Luca Soraci

submission deadline 20 Jun 2026 | Viewed by 382 | Submission Open

Keywords: aging; dementia; neuroinflammation; kidney– brain axis; translational research; biomarkers; oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Structural and Functional Insights into Chemokines and Chemokine Receptors in Immune Pathologies

edited by

Nidhi Joshi

submission deadline 20 Jun 2026 | Viewed by 378 | Submission Open

Keywords: chemokines; chemokine receptors; immune pathologies; signaling mechanisms; therapeutic targeting

(This special issue belongs to the Section Molecular Immunology)

Innovations in Photodynamic Therapy: New Horizons in Breast Cancer Care

edited by Sandeep Surendra Panikar

submission deadline 20 Jun 2026 | Viewed by 375 | Submission Open

Keywords: noninvasive therapy; tumor targeting; breast cancer therapy; oncology; photosensitizers; theranostics; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Molecular Characterization of Glioblastoma: Implications for Diagnosis and Personalized Treatment

edited by Madan Mohan Kwatra

submission deadline 20 Jun 2026 | Viewed by 375 | Submission Open

Keywords: glioblastoma; diagnosis; molecular characterization; personalized treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Combined and Mixture Exposure Toxicology of Cancer and Chronic Diseases

edited by

Alok Deoraj

and Quentin Felty

submission deadline 20 Jun 2026 | Viewed by 358 | Submission Open

Keywords: combined exposure; mixture exposure; toxicology of cancer; omics of cancer; AI in carcinogenesis; machine learning use in cancer; cancer biomarkers; pollutants of cancer; agrochemicals; endocrine-disruptive chemicals

(This special issue belongs to the Section Molecular Oncology)

Neurobiology and Psychopharmacology of Mood Disorders

edited by

Luca Steardo

submission deadline 20 Jun 2026 | Viewed by 356 | Submission Open

Keywords: mood disorders; psychopharmacology; neurobiology; molecular mechanisms; biomarkers; translational psychiatry; neuroinflammation; signal transduction; animal models; epigenetics

(This special issue belongs to the Section Molecular Neurobiology)

Advanced in In Silico Methods for Rational Drug Design and Predictive Toxicology

edited by

Gnanendra Shanmugam

submission deadline 20 Jun 2026 | Viewed by 352 | Submission Open

Keywords: rational drug design; predictive toxicology; molecular modeling; AI in drug discovery; QSAR; molecular docking; ADMET

(This special issue belongs to the Section Molecular Informatics)

Molecular Horizons in Pain Therapeutics

edited by Alaa Abd-Elsayed

submission deadline 20 Jun 2026 | Viewed by 346 | Submission Open

Keywords: spinal cord stimulation; peripheral nerve stimulation; stem cell therapy; platelet-rich plasma (PRP) injections; chronic pain management; interventional pain procedure

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Bioactive Compounds for Human Health, 3rd Edition

edited by

Hongjie Zhang

submission deadline 20 Jun 2026 | Viewed by 345 | Submission Open

Keywords: natural bioactive plant products; biological and pharmacological activity; natural plant drug discovery and development; nutraceuticals; botanical dietary supplement

(This special issue belongs to the Section Molecular Pharmacology)

Cellular Mechanisms of Pulmonary Arterial Hypertension

edited by

David P Marciano

and Saurabh Aggarwal

submission deadline 20 Jun 2026 | Viewed by 334 | Submission Open

Keywords: pulmonary arterial hypertension (PAH); pulmonary vascular remodeling; endothelial cells; endothelial dysfunction; smooth muscle cells; hyperplasia; pericytes; fibroblasts; monocytes; macrophage; neutrophil; mechanotransduction; oxidative stress; cytokines; extracellular vesicles; extracellular matrix; epigenetics; metabolism; biomarkers; therapeutics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Surfactants: Design, Synthesis and Properties

edited by

Joanna Krawczyk

submission deadline 20 Jun 2026 | Viewed by 331 | Submission Open

Keywords: design and synthesis of surfactants; adsorption and aggregation properties of surfactants; behavior of surfactants at different interfaces; application of biosurfactants and specialist surfactants (industry; agriculture; medicine; pharmacy)

(This special issue belongs to the Section Materials Science)

Advances in Autoimmune Diseases: The Molecular Basis and New Therapies

edited by

Adawi Mohammad

submission deadline 20 Jun 2026 | Viewed by 327 | Submission Open

Keywords: autoimmunity; molecular mechanisms; biologics; immunotherapy; precision medicine

(This special issue belongs to the Section Molecular Immunology)

Eukaryotic Cells Under Stress: Biochemical and Physiological Mechanisms of Resistance and Resilience

edited by

Bruno Hay Mele

and

Carmen Arena

submission deadline 20 Jun 2026 | Viewed by 324 | Submission Open

Keywords: cellular stress response; oxidative stress; bioactive compounds; ROS; DNA damage/repair; environmental stressors; molecular chaperones; antioxidant in human diseases

(This special issue belongs to the Section Molecular Biology)

Sustainable Material Development: From Molecular Insights to Functional Applications

edited by

Rosie Yagmur Yegin

submission deadline 20 Jun 2026 | Viewed by 323 | Submission Open

Keywords: sustainable materials; biodegradable polymers; green chemistry; functional materials; structure– property relationships; chemical modification; recycling and upcycling; circular economy; composites; analytical techniques

(This special issue belongs to the Section Materials Science)

Consensus-Based Approaches to Rational Drug Design and Predictive Toxicology

edited by

Fernando Daniel Prieto-Martínez

submission deadline 20 Jun 2026 | Viewed by 320 | Submission Open

Keywords: drug design; bioactive compounds; pharmacophore; molecular dynamics; protein– ligand interactions; activity cliffs; machine learning

(This special issue belongs to the Section Molecular Toxicology)

Cell and Molecular Biology of Archaea

edited by

Federica De Lise

submission deadline 20 Jun 2026 | Viewed by 319 | Submission Open

Keywords: archaea; molecular biology; translation; gene expression regulation; biofilm; metabolism

(This special issue belongs to the Section Molecular Microbiology)

Infectious Diseases and Infection Models in Laboratory Animals

edited by

Hiraku Sasaki

and Fumio Ike

submission deadline 20 Jun 2026 | Viewed by 319 | Submission Open

Keywords: infection model; Infectious diseases in laboratory animals; bacterial infection; viral infection; parasitic infection; molecular diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Design and Engineering of Carbon-Based Materials for Environmental Remediation and Bioenergy

edited by Hilda Elizabeth Reynel-Ávila

submission deadline 20 Jun 2026 | Viewed by 316 | Submission Open

Keywords: adsorption; catalysis; functionalization; molecular design; environmental; sustainable energy; tailoring

(This special issue belongs to the Section Materials Science)

Precision Medicine for Cancer-Associated Thrombosis: The Role of Biomarkers

edited by Darko Antic

submission deadline 20 Jun 2026 | Viewed by 314 | Submission Open

Keywords: biomarkers; precision medicine; cancer-associated thrombosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Unraveling Bioactive Peptides: Structure, Function, and Applications

edited by

Sara Elsa Aita

submission deadline 20 Jun 2026 | Viewed by 314 | Submission Open

Keywords: bioactive peptides; peptide structure– activity relationship; peptidomics; bioactivity assays; human health

(This special issue belongs to the Section Macromolecules)

Molecular Insights into Skin Health and Disease

edited by

Federica Li Pomi

submission deadline 20 Jun 2026 | Viewed by 314 | Submission Open

Keywords: dermatology; molecular mechanisms; targeted therapy; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Stress Signaling and Horticultural Crops Quality Control

edited by

Weibiao Liao

and

Yanjie Xie

submission deadline 20 Jun 2026 | Viewed by 312 | Submission Open

Keywords: stress tolerance; molecular mechanisms; quality traits; redox regulation; postharvest physiology; signal transduction

(This special issue belongs to the Section Molecular Plant Sciences)

Graphene-Based Nanocomposites

edited by

Oleksandr Ivasenko

submission deadline 20 Jun 2026 | Viewed by 311 | Submission Open

Keywords: graphite intercalates; graphene; reduced graphene oxide; grafting; vertical heterostructures; nanocomposites; covalent organic frameworks (COFs); 2D nanomaterials; biomimetic interfaces; interfacial engineering

(This special issue belongs to the Section Molecular Nanoscience)

Interstitial Lung Diseases: From Molecular Pathology to New Treatments

edited by

Yasuhiko Koga

submission deadline 20 Jun 2026 | Viewed by 309 | Submission Open

Keywords: interstitial lung diseases (ILDs); therapeutic strategies; molecular pathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Neuropharmacology in Neurodegenerative Disorders

edited by

Ichiro Kawahata

submission deadline 20 Jun 2026 | Viewed by 302 | Submission Open

Keywords: neuropharmacology; neurodegenerative disorders; cognitive dysfunction; motor dysfunction; drug discovery; neuroprotection; neurogenesis; brain plasticity; biomarkers; AI (artificial intelligence)

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Regulatory Mechanisms of the Tumor Microenvironment in Human Diseases

edited by

Cornelia Amalinei

and

Adriana Grigoraș

submission deadline 20 Jun 2026 | Viewed by 301 | Submission Open

Keywords: tumor microenvironment; cytokines; exosomes; non-tumor cells; tumor-associated immune cells; cancer prognosis; cancer diagnosis; oncotherapy

(This special issue belongs to the Section Molecular Oncology)

From Discovery to Clinic: Overcoming Barriers in Antimicrobial Peptide Development

edited by José M. Pérez De la Lastra

submission deadline 20 Jun 2026 | Viewed by 297 | Submission Open

Keywords: antimicrobial peptides (AMPs); translational challenges; in vivo efficacy; drug delivery and formulation; computational approaches; pharmacokinetics; toxicity prediction; antibiotic resistance; animal models; nanotechnology

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanisms of Biotic and Abiotic Stress Responses in Trees

edited by

Chenghao Li

submission deadline 20 Jun 2026 | Viewed by 296 | Submission Open

Keywords: drought stress; nutrient deficiency; salinity stress; pathogen defense; transcriptional regulation; epigenetic modifications; signal transduction; bioinformatics & multi-omics analysis; breeding for stress resilience

(This special issue belongs to the Section Molecular Plant Sciences)

Progress in Molecular Breeding and Genetic Engineering for Fruit Crop Improvement

edited by

Amelia Salimonti

submission deadline 20 Jun 2026 | Viewed by 291 | Submission Open

Keywords: genetics; GWAS; genome; abiotic and biotic stress; transcriptomic analysis; fruit crop germplasm; breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Advanced Research on Antioxidant Activity

edited by Agnieszka Filipek

submission deadline 20 Jun 2026 | Viewed by 290 | Submission Open

Keywords: antioxidants; advanced mechanisms of action; signaling pathways; molecular mechanism; biologically active compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Trends in Green Synthesis of Nanomaterials

edited by Rocío Redón

submission deadline 20 Jun 2026 | Viewed by 287 | Submission Open

Keywords: nanoparticles; cytotoxicity; drug delivery; nanomaterials; green synthesis

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Insights into Mechanobiology of Regeneration

edited by

Christopher Robinson

and Timothy R. Deer

submission deadline 20 Jun 2026 | Viewed by 282 | Submission Open

Keywords: mechanotransduction; regeneration; stem cells; extracellular matrix; tissue repair

(This special issue belongs to the Section Molecular Biophysics)

New Perspectives in Protein Structure

edited by

Csaba Magyar

submission deadline 20 Jun 2026 | Viewed by 273 | Submission Open

Keywords: stability of protein complexes structural; background of protein function; allosteric regulation of proteins; fuzzy complexes; intrinsically disordered proteins; liquid-liquid phase separation; mutual synergistic folding; protein folding; protein structure; protein-protein interactions; transmembrane proteins

(This special issue belongs to the Section Molecular Biophysics)

Displaying special issue 801-850 on page 17 of 67.

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