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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Growth Hormone Deficiency: Molecular Pathologies and Therapeutic Strategies
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 2190 | Submission Open
Keywords: growth hormone (GH); growth hormone deficiency (GHD); growth hormone therapy; long-acting growth hormone (LAGH); insulin-like growth factor-1 (IGF-1); growth hormone secretagogues; signaling pathways of the GH-IGF-1 axis; transition phase
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advanced Research on Immune Cells and Cytokines (2nd Edition)
edited by
submission deadline 30 Nov 2024 | 4 articles | Viewed by 2144 | Submission Open
Keywords: immune cells; cytokines; immunomodulatory treatments; immune diseases; immune system
(This special issue belongs to the Section Molecular Immunology)
Organoids and Organs-on-Chip for Medical Research
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 1938 | Submission Open
Keywords: organoids; organs-on-chip; tissue engineering; disease modeling; biomarkers; molecular pathways; nanotechnology; preclinical models; artificial organs; artificial intelligence; personalized medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Glycosaminoglycans, 2nd Edition submission deadline 30 Nov 2024 | 2 articles | Viewed by 1929 | Submission Open
Keywords: biosynthesis of glycosaminoglycans; hyaluronan; chondroitin sulfate; heparin; modified GAGS; GAG bioactivity; GAGs as biomarkers; novel characterization methods; GAGs as drug or drug carriers; GAG= interaction with cells; in vitro cell-based assays; innovative biofabrication methodology based on GAGs; 3D scaffolds based on GAGs
(This special issue belongs to the Section Macromolecules)
The Roles of Histamine and Its Receptor Ligands in Central Nervous System Disorders
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1850 | Submission Open
Keywords: histamine; histamine receptor; neurodegenerative diseases; sleep disorders; neuropsychiatric disorders; schizophrenia; cognition; heterogeneity  
(This special issue belongs to the Section Molecular Neurobiology)
Cell Apoptosis, 3rd Edition
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1842 | Submission Open
Keywords: apoptosis; caspase; cell cycle; cytotoxicity; reactive oxygen species
(This special issue belongs to the Section Molecular Biology)
Lipidomics and Lipid Metabolism in Health and Disease
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1841 | Submission Open
Keywords: lipidomics; lipid metabolism; lipid signaling; lipid homeostasis; metabolic disease; lipid biomarkers; fatty acids; phospholipids; sphingolipids; cholesterol
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular and Metabolic Insights into Neuroinflammation and Neurodegeneration
edited by and Marika Lanza
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1825 | Submission Open
Keywords: Parkinson’ s disease; Alzheimer’ s disease; metabolism; inflammation; neurodegeneration; drug discovery; pharmacological therapy
(This special issue belongs to the Section Molecular Neurobiology)
Primary and Secondary Bladder Disorders in Neurourology and Inflammatory Diseases submission deadline 30 Nov 2024 | 2 articles | Viewed by 1810 | Submission Open
Keywords: bladder ischemia; bladder pain syndrome; interstitial cystitis; irradiation cystitis; ketamine cystitis; microbiota; overactive bladder; underactive bladder; botulinum toxin for bladder disorders
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
RNA Biology and Regulation
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 1782 | Submission Open
Keywords: RNA processing; RNA transport; RNA localization; RNA editing; RNA synthesis; RNA stability; RNA modification; translation; transcription; RNA metabolism; human diseases
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Diagnostics and Treatment of Inflammatory Bowel Disease submission deadline 30 Nov 2024 | 1 articles | Viewed by 1776 | Submission Open
Keywords: IBD molecular pathogenesis; intestinal mucosal healing; gut microbiota in IBD; fecal microbiota transplantation; target therapy in IBD; stem cell therapy; biologic agents; small molecules; adhesion antagonists; inflammatory cytokines; lymphocyte control
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Proteomics and Nanotechnology for Medical and Pharmacological Applications
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1771 | Submission Open
Keywords: biomolecules; peptides; proteomics; transcriptomics; nanotechnology; venomics
(This special issue belongs to the Section Molecular Pharmacology)
Functional Roles of Epithelial and Endothelial Cells submission deadline 30 Nov 2024 | 2 articles | Viewed by 1770 | Submission Open
Keywords: epithelial cells; wound healing; endothelial cells; skin; cornea; functionality; barrier
(This special issue belongs to the Section Biochemistry)
Editorial Board Members’ Collection Series: “Bacterial Enzymes as Targets” submission deadline 30 Nov 2024 | 1 articles | Viewed by 1735 | Submission Open
Keywords: enzymes; cell wall biosynthesis; DNA replication; metabolic pathway; vital bacterial function; enzyme inhibition; antibacterial agents; antibiotic resistance
(This special issue belongs to the Section Biochemistry)
Editorial Board Members’ Collection Series: “Emerging Progress in Nanomedicine”
edited by Hamed Laroui and
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1706 | Submission Open
Keywords: nanomedicine; nanoparticles; nanotechnology; targeted drug delivery; pharmaceutical nanoimaging; nanoengineering; nanotoxicology
(This special issue belongs to the Section Molecular Nanoscience)
Effects of Environmental Contaminants on Cell Signaling Pathways
edited by Brad L. Upham
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1692 | Submission Open
Keywords: cell signaling; environmental contaminants; signal transduction; gap junction; toxic mechanisms
(This special issue belongs to the Section Molecular Biology)
Advancements in Pincer Ligand Chemistry
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 1673 | Submission Open
Keywords: pincer ligands; metal complexes; tridentate ligands; catalysis; organometallic chemistry; homogenous catalysis; ligand tunability
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Molecular Biology and the Genetic Breeding of Aquatic Animals: Breakthroughs and Challenges
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 1636 | Submission Open
Keywords: transgenic; genetic breeding; omics; gene expression and regulation; aquatic animals
(This special issue belongs to the Section Molecular Biology)
Molecular Research in Infective Mycobacteria
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1634 | Submission Open
Keywords: infections; mycobacteria; molecular biology; antimicrobials; bacteria biochemistry
(This special issue belongs to the Section Molecular Microbiology)
Roles and Mechanisms of Non-coding RNAs in Human Health and Disease submission deadline 30 Nov 2024 | 2 articles | Viewed by 1572 | Submission Open
Keywords: non-coding RNAs; microRNAs; long non-coding RNAs; circular RNAs; biomarkers; polymorphisms; cancer; degenerative diseases; therapy
(This special issue belongs to the Section Molecular Genetics and Genomics)
Bioactive Compounds in the Prevention of Chronic Diseases submission deadline 30 Nov 2024 | 1 articles | Viewed by 1528 | Submission Open
Keywords: bioactives; chronic disease; inflammation; oxidative stress; obesity; diabetes; cancer
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Recent Research of Natural Products from Microalgae and Cyanobacteria
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1523 | Submission Open
Keywords: marine and fresh water microalgal and cyanobacterial bioactive compounds; microalgal and cyanobacterial carotenoids; vitamins; phenolics; and phycobiliproteins; microalgal and cyanobacterial alkaloids; microalgal and cyanobacterial polysaccharides; microalgal and cyanobacterial peptides; microalgal and cyanobacterial polyphenols; microalgal and cyanobacterial antioxidants; microalgal and cyanobacterial pharmaceuticals; microalgal and cyanobacterial nutraceuticals; microalgal and cyanobacterial anti-inflammatory compounds; microalgal and cyanobacterial antimicrobial compounds; microalgal and cyanobacterial anticancer compounds; microalgal and cyanobacterial neuroprotective compounds; microalgal and cyanobacterial antiviral compounds; microalgal and cyanobacterial-derived anti-aging compounds; microalgal and cyanobacterial extracts
(This special issue belongs to the Section Biochemistry)
Molecular Research Landscape of Pulmonary Arterial Hypertension
edited by Cármen Brás-Silva
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1495 | Submission Open
Keywords: pulmonary arterial hypertension; right ventricle; right heart failure; molecular mechanisms; vascular disease; translational research; therapy
(This special issue belongs to the Section Molecular Biology)
Recent Progress on Toxins in Pharmacology and Drug Discovery
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 1454 | Submission Open
Keywords: sodium channels; potassium channels; calcium channels; chloride ion channels; TRP channels; ASIC channels; opiate receptors; acetylcholine receptors; NMDA receptor; antibiotics; antimicrobial peptides; botulinum toxins; cone snail venom peptides; spider venom peptides; amphibian peptides; sea anemone toxins; scorpion toxins; snake toxins; centipede toxins  
(This special issue belongs to the Section Molecular Toxicology)
Novel Insights into the Molecular Bases of Congenital Eye Abnormalities
edited by Julie Plaisancié, and Marta Corton-Pérez
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1418 | Submission Open
Keywords: genetics; genome sequencing; gene regulation; pathways; micro-anophthalmia; coloboma; anterior segment dysgenesis; developmental eye disorders; eye development; animal model; organoids
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights into Cancer Metabolism, Metastasis, and Immune Evasion
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 1409 | Submission Open
Keywords: cancer metabolism; metastasis; immune evasion; tumor– immune interactions; combination therapy
(This special issue belongs to the Section Molecular Oncology)
Advances in Heart Diseases: Molecular Pathogenesis, Biomarkers and Therapies
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1356 | Submission Open
Keywords: heart diseases; biomarkers; molecular pathways; personalized medicine; interventional therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Neurodevelopmental-Related Disorders
edited by Joana M. Marques
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1322 | Submission Open
Keywords: neurodevelopmental disorders; neuropsychiatric disorders; neurological disorders; genetic defects; environmental-driven defects; neurogenesis; neuronal migration; neuronal differentiation; synaptogenesis; biomarkers
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanisms and Treatment Strategies of Myocardial Infarction
edited by Abdul-Majeed Salmasi
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1281 | Submission Open
Keywords: myocardial infarction; genetics; molecular biology; chromosomes; genes; atherosclerosis; coronary artery disease; risk factors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Biomedical Applications of Mesenchymal Stem Cells
edited by and
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1273 | Submission Open
Keywords: mesenchymal stem cells; cell differentiation; cell therapy; regenerative medicine; tissue homeostasis; cartilage
(This special issue belongs to the Section Molecular Pharmacology)
The Role of Environment in Amyloid Aggregation: 3rd Edition
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 1251 | Submission Open
Keywords: protein misfolding; protein aggregation; amyloid; anti-amyloid compounds; amyloid polymorphism; prion; protein folding and stability; neurodegenerative diseases; aggregation kinetics; drug discovery
(This special issue belongs to the Section Molecular Biophysics)
Molecular Advances in Heart Disease: Genomics, Proteomics, and Bioinformatics of Heart Research
edited by Justyna Fert-Bober
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1099 | Submission Open
Keywords: heart disease; cardiovascular disease; coronary artery disease (CAD); heart attack; heart failure; arrhythmia (abnormal heart rhythms); valve disease; high blood pressure; congenital heart conditions; inherited heart conditions; fibrosis; pathobiology of fibrosis; aging; chronic inflammation; inflammatory and cardiovascular diseases; myocarditis; extracellular matrix biology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Innate Immunity: New Insights into Genetic and Signaling Networks
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1061 | Submission Open
Keywords: innate immunity; innate immune response; signaling pathways; genetic variations
(This special issue belongs to the Section Molecular Immunology)
The Endocannabinoid System: New Insights into Its Role in Health and Disease 2.0 submission deadline 30 Nov 2024 | 1 articles | Viewed by 1055 | Submission Open
Keywords: cannabinoids; cannabinoid receptors; drug development; diagnostics; phytocannabinoids; synthetic cannabinoids
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Quantum Dots for Biomedical Applications submission deadline 30 Nov 2024 | 2 articles | Viewed by 1032 | Submission Open
Keywords: quantum dots; molecular imaging; tissue imaging: biosensing; medical diagnosis; drug delivery
(This special issue belongs to the Section Materials Science)
Hematologic Diseases: Molecular Insights and Novel Methods
edited by and Samantha Bruno
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1029 | Submission Open
Keywords: hematologic malignancies; high-throughput technologies; omics data; biomarkers; drug resistance; minimal residual disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Biology of Tumor Cells: Present and Future submission deadline 30 Nov 2024 | 1 articles | Viewed by 1015 | Submission Open
Keywords: molecular immunology of cancer; ubiquitin-proteasome system in cancer; microRNA in cancer; extracellular matrix in cancer; metalloproteinases; cancer stem cells; ROS; molecular prognosis and diagnosis of cancer; cancer epigenetics
(This special issue belongs to the Section Molecular Oncology)
Neurological Diseases: From Molecular Basis to Therapy
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 974 | Submission Open
Keywords: neurological diseases; pathogenesis; therapy; personalized medicine; early diagnosis; genetics; neurology; pharmacology
(This special issue belongs to the Section Molecular Neurobiology)
Advances in Molecular Modeling, Docking and Simulations of Protein Structure, 2nd Edition
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 965 | Submission Open
Keywords: molecular modeling; protein structure; molecular mechanisms; protein interactomics; ligand design; peptides; molecular dynamics; molecular docking
(This special issue belongs to the Section Macromolecules)
Plant–Microbe Interactions
edited by Jian Jin
submission deadline 30 Nov 2024 | 1 articles | Viewed by 940 | Submission Open
Keywords: plant; crop; rhizosphere microbiome; microbial colonization; quorum sensing; endophytic microbes
(This special issue belongs to the Section Molecular Plant Sciences)
Advances in Lupus Erythematosus and Lupus Nephritis: Pathogenesis, Biomarkers and Treatments
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 937 | Submission Open
Keywords: lupus erythematosus; lupus nephritis; SLE; LN; organ damage; pathogenesis; biomarkers; genomic; transcriptomic; metabolomic; treatments; therapeutic
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Food Science and Molecular Nutrition
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 910 | Submission Open
Keywords: food science; antioxidants; bioactive compounds; mitochondria; nutrigenomics; metabolomics
(This special issue belongs to the Section Biochemistry)
Molecular Advances in Ovarian Cancer: 2nd Edition
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 905 | Submission Open
Keywords: pathogenesis; tumor microenvironment; ovarian cancer
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research on Kidney Disease/Renal Dysfunction
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 887 | Submission Open
Keywords: kidney disease/renal dysfunction; hypoxia-inducible factor-prolyl hydroxylase (HIF-PHD) inhibitors; renal anemia; chronic renal faikure
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nutrient in the Plants: Friend or Foe?
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 885 | Submission Open
Keywords: plant nutrient; essential elements; beneficial elements; plant growth; plant development; cellu-lar mechanism; molecular mechanism; hyperaccumulation; hypertolerance; new-type fertilizer
(This special issue belongs to the Section Molecular Plant Sciences)
Computational Biophysics and Bioinformatics of Proteins
edited by
submission deadline 30 Nov 2024 | Viewed by 876 | Submission Open
Keywords: protein; computational biophysics; bioinformatics; protein dynamics; protein– ligand binding; protein– protein interaction; proteins’ structure and function; drug discovery
(This special issue belongs to the Section Molecular Biophysics)
Molecular Pharmacology of Medicinal Plants
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 863 | Submission Open
Keywords: medicinal plants; drug development; molecular pharmacology; clinical phytopharmacology
(This special issue belongs to the Section Molecular Pharmacology)
Recent Advances in Electrochemical-Related Materials
edited by Celia García-Hernandez
submission deadline 30 Nov 2024 | 1 articles | Viewed by 829 | Submission Open
Keywords: novel electrochemical devices; advanced micro- and nanomaterials for electrochemical applications; batteries; fuel and photoelectrochemical cells; electrochemical sensors and biosensors; new advances in supercapacitors; electrochemical electrolyzers; advanced electrochemical materials for environmental applications
(This special issue belongs to the Section Materials Science)
Molecular Biomarkers in Cancers: Advances and Challenges, 2nd Edition submission deadline 30 Nov 2024 | 1 articles | Viewed by 811 | Submission Open
Keywords: cancer; cancer staging; diagnostic tools; novel biomarkers; proteomics; molecular markers; metabolic profiling; prognostic value
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Research on Cyclodextrin
edited by Valentina Giglio
submission deadline 30 Nov 2024 | 1 articles | Viewed by 791 | Submission Open
Keywords: drug delivery systems; polymeric cyclodextrin; pollution removal; sponge-like material; selective targeting systems; catalyst
(This special issue belongs to the Section Materials Science)
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