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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Biology of the Thyroid Cancer and Thyroid Dysfunctions
edited by Vija Lavinia
submission deadline 30 Nov 2024 | 7 articles | Viewed by 10121 | Submission Open
Keywords: animal models; apoptosis; autophagy; cancer biomarker; cancer epidemiology; cancer prevention; cancer screening; cholesterol metabolism; clinical trial; DNA repair; epigenomics; genome instability; genomic database; genomics; invasion; metabolomics; metastasis; methylation; microarray; microRNA; molecular diagnostics; molecular tumor pathology; next-generation sequencing; noncoding RNA; omics; personalized medicine; prognosis; proteomics; radionuclide therapy; signaling pathway; SNP genotyping; targeted therapy; theranostics; thyroid cancer; hyperthyroidism; therapeutic targets; translational cancer research; treatment response; tumor microenvironment
(This special issue belongs to the Section Molecular Oncology)
Mixed Biofilms: Interbacterial Interactions and Antimicrobial Susceptibility
edited by
submission deadline 30 Nov 2024 | 4 articles | Viewed by 9029 | Submission Open
Keywords: bacteria; micromycetes; biofilm; mixed biofilm; susceptibility to antimicrobials; synergy; molecular mechanisms of interbacterial interaction
(This special issue belongs to the Section Molecular Microbiology)
Antioxidant, Anti-inflammatory, and Antiproliferative Activities of Natural Products—2nd Edition
edited by
submission deadline 30 Nov 2024 | 7 articles | Viewed by 8740 | Submission Open
Keywords: bioactive products; anti-infectives; antioxidants; anti-inflammatory; antiproliferative; clinical phytopharmacology; phytopharmacology; polyphytotherapy
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Transcription Factors in Lung Cancer: Mechanisms and Future Perspectives submission deadline 30 Nov 2024 | 4 articles | Viewed by 8455 | Submission Open
Keywords: transcription factors; lung cancer; NSCLC SCLC; targeting; biomarkers; tumor suppressors; oncogenes; transcription factor network; computational models
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Dermatology: Advances in Pathophysiology and Therapies (2nd Edition)
edited by , Belén De la Hoz and
submission deadline 30 Nov 2024 | 4 articles | Viewed by 8249 | Submission Open
Keywords: immunodermatology; cutaneous lymphoma; cutaneous drug reaction; erythroderma; psoriasis; atopic dermatitis; eczematous reactions; cutaneous manifestation of systemic diseases; cutaneous vasculitis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advanced Research on Regenerative Medicine submission deadline 30 Nov 2024 | 4 articles | Viewed by 7971 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Plant Genome Editing
edited by Lei Gao
submission deadline 30 Nov 2024 | 5 articles | Viewed by 7850 | Submission Open
Keywords: plant genome editing; Cas9/Cas12a; CRISPR/CRISPRa/CRISPRi; anti-CRISPR; gene editing; off target impact; prime editing; bioinformatics/database
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular and Cellar Research of Spine and Spinal Cord Injury
edited by and Joanne Tipper
submission deadline 30 Nov 2024 | 3 articles | Viewed by 7837 | Submission Open
Keywords: pine; spinal cord; intervertebral disc; tissue engineering; regenerative medicine; cell therapy; molecular therapy; injury models; organ-on-a-chip and microfluidic systems for cell therapy; mechanobiology; spinal implants wear particle; safety and efficacy
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanisms of Plant Biostimulants
edited by and Julietta Moustaka
submission deadline 30 Nov 2024 | 5 articles | Viewed by 7754 | Submission Open
Keywords: biostimulants; abiotic stresses; biotic stresses; plant growth promoter; stress acclimation; oxidative damage; photosynthetic efficiency; ROS; antioxidant mechanisms; redox regulation
(This special issue belongs to the Section Molecular Plant Sciences)
Antimicrobial Peptides: Structure and Mechanism of Biological Activity: 3rd Edition
edited by
submission deadline 30 Nov 2024 | 5 articles | Viewed by 7732 | Submission Open
Keywords: antimicrobial peptides; mechanism of biological activity; functional diversity of peptides; structural analysis of peptides; dynamic conformation of peptides; lipid composition of the cell membrane; peptide– lipid interactions; peptide self-association; peptide-lipid complex formation; peptide– intracellular receptor interaction; peptide translocation through membrane; cell morphology; peptide interaction with infectious agents; surface properties of the cell; peptide interaction with the cell in vivo
(This special issue belongs to the Section Molecular Microbiology)
The Application of Biomaterials in Bone Tissue Repair and Regeneration
edited by
submission deadline 30 Nov 2024 | 4 articles | Viewed by 7487 | Submission Open
Keywords: allograft; autograft; autologous bone; bone; graft materials; mineral substitutes; regeneration
(This special issue belongs to the Section Materials Science)
Molecular Insights into Sphingolipids
edited by
submission deadline 30 Nov 2024 | 4 articles | Viewed by 6991 | Submission Open
Keywords: sphingolipids; ceramide; sphingosine; sphingosine 1-phosphate; ceramide 1-phosphate; glycosphingolipids; diabetes; insulin resistance; beta-cell failure; NAFLD; cardiovascular disease; metabolic dysfunction
(This special issue belongs to the Section Molecular Biology)
Molecular Advances in Epilepsy and Seizures
edited by Sara Matricardi
submission deadline 30 Nov 2024 | 4 articles | Viewed by 6984 | Submission Open
(This special issue belongs to the Section Molecular Neurobiology)
The Role of Natural Compounds in Cancer and Inflammation
edited by
submission deadline 30 Nov 2024 | 5 articles | Viewed by 6739 | Submission Open
Keywords: natural compounds; oxidative stress; anti-cancer; anti-inflammatory; natural product synthesis and biological activities
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advances in Plant Virus Diseases and Virus-Induced Resistance
edited by and Muqing Zhang
submission deadline 30 Nov 2024 | 6 articles | Viewed by 6415 | Submission Open
Keywords: virus detection; virus characterization; virus resistance; gene silencing; epigenetic regulation
(This special issue belongs to the Section Molecular Plant Sciences)
Development, Characterization and Applications of Novel Polymeric Materials and Composites submission deadline 30 Nov 2024 | 5 articles | Viewed by 6261 | Submission Open
Keywords: diagnosis; therapy; polymers; composite materials; theoretical model
(This special issue belongs to the Section Macromolecules)
The Role of Cytokines in Diseases submission deadline 30 Nov 2024 | 4 articles | Viewed by 6049 | Submission Open
Keywords: cytokines; inflammation; immune response; genetics; epigenetics; disease; infection; pathogen-associated molecular patterns; damage-associated molecular patterns; pattern-recognizing receptors; treatment
(This special issue belongs to the Section Biochemistry)
New Insights into Antimicrobial Nanoparticles: From Mechanisms to Applications
edited by
submission deadline 30 Nov 2024 | 3 articles | Viewed by 5887 | Submission Open
Keywords: antimicrobial nanoparticles; alternative to antibiotics; physical and chemical activation of nanoparticles; multi-drug resistance; mechanisms of anti-infective action
(This special issue belongs to the Section Molecular Nanoscience)
New Insights into Gut Microbiota and Immunity
edited by
submission deadline 30 Nov 2024 | 4 articles | Viewed by 5508 | Submission Open
Keywords: gut; microbiota; immune response; infectious disease; cancer; brain function; metabolism; endocrine signaling; pathological conditions; therapy
(This special issue belongs to the Section Molecular Immunology)
External Stimuli-Responsive Nanomaterials for Diagnosis and Treatment
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 5504 | Submission Open
Keywords: nanotechnology; external stimuli-responsive nanomaterials; nanotheranostic systems; biodetection; bioimaging; plasmonics
(This special issue belongs to the Section Molecular Nanoscience)
Autophagy, Cellular Senescence and Oxidative Stress in Ageing and Age-Related Diseases
edited by
submission deadline 30 Nov 2024 | 3 articles | Viewed by 5297 | Submission Open
Keywords: autophagy; oxidative stress; antioxidants; homeostasis; senescence; ageing; age-related diseases; reactive oxygen species; macromolecular damage; cytotoxic stress
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Innovative In Vitro Model for Medical, Pharmaceutical and Diagnostic Applications submission deadline 30 Nov 2024 | 4 articles | Viewed by 5210 | Submission Open
Keywords: in vitro 3D models; organoids; drug and nutraceutical screening; preclinical imaging; tissue engineering; precision and regenerative medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Stress, Immunity, and Tissue Microenvironment: 2nd Edition submission deadline 30 Nov 2024 | 2 articles | Viewed by 4960 | Submission Open
(This special issue belongs to the Section Molecular Immunology)
Molecular Therapeutics for Diabetes and Related Complications
edited by
submission deadline 30 Nov 2024 | 6 articles | Viewed by 4690 | Submission Open
Keywords: diabetes; diabetes complications; molecular therapeutics; drug development; hyperglycemia; insulin resistance; cell signaling and oxidative stress
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Occurrence, Evolution and Treatment of Glioblastoma: Second Edition submission deadline 30 Nov 2024 | 4 articles | Viewed by 4607 | Submission Open
Keywords: GBM; low-grade and high-grade; pediatric diffuse gliomas; signaling pathways in GBMs; recurrent gliomas; midbrain gliomas; radiomics in brain tumors; re-surgery and re-radiation in GBMs; immunotherapy; targeted therapies for GBMs
(This special issue belongs to the Section Molecular Oncology)
Gene Transfer in Brain Disorders
edited by , Lluís Samaranch and Anne-Marie Duchemin
submission deadline 30 Nov 2024 | 1 articles | Viewed by 4604 | Submission Open
Keywords: intellectual disability; neurodegenerative disorders; psychiatric diseases; gene transfer; AAV
(This special issue belongs to the Section Molecular Neurobiology)
Nanoparticles in Nanobiotechnology and Nanomedicine: 2nd Edition
edited by
submission deadline 30 Nov 2024 | 3 articles | Viewed by 4480 | Submission Open
Keywords: nanoparticles; properties of nanoparticles; methods of obtaining nanoparticles; characterization techniques; theoretical models; computational simulation; applications in nanomedicine; applications in nanobiotechnology
(This special issue belongs to the Section Molecular Nanoscience)
Cellular and Molecular Biology of Mitochondria in Human Health and Diseases
edited by
submission deadline 30 Nov 2024 | 3 articles | Viewed by 4287 | Submission Open
Keywords: mitochondria; mitophagy; oxidative phosphorylation; apoptosis; integrated stress response; heteroplasmy; calcium dynamics; reactive oxygen species; fusion/fission; mitochondrial quality control
(This special issue belongs to the Section Molecular Biology)
The Role of Bioactive Compounds in Human Health and Disease: 2nd Edition
edited by
submission deadline 30 Nov 2024 | 5 articles | Viewed by 3962 | Submission Open
Keywords: cancer; inflammation; cardiovascular diseases; plants; bioactive compounds
(This special issue belongs to the Section Molecular Pharmacology)
Serotonin in Health and Diseases submission deadline 30 Nov 2024 | 2 articles | Viewed by 3829 | Submission Open
Keywords: components of serotonergic system; serotonin targets; related systems; serotonergic mechanisms; experimental models
(This special issue belongs to the Section Biochemistry)
Molecular Perspective of Cardiovascular Diseases
edited by
submission deadline 30 Nov 2024 | 4 articles | Viewed by 3824 | Submission Open
Keywords: cardiovascular diseases; cardiology; inflammation; atherosclerosis; cardiomyopathy; endothelial cell
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances in Helicobacter pylori Infections and Treatments
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 3813 | Submission Open
Keywords: H. pylori; gastritis; carcinogenesis; mechanisms of pathogenicity; molecular pathology; molecular genetics; microbiome modulation; antibiotic resistance; eradication  
(This special issue belongs to the Section Molecular Microbiology)
Novel Insight into Epigenomic Studies of Human Disease
edited by and Takashi Ito
submission deadline 30 Nov 2024 | 4 articles | Viewed by 3719 | Submission Open
Keywords: epigenetic regulation; DNA methylation; protein methylation; protein acetylation; histone modification; noncoding RNAs (ncRNAs); post-translational modifications (PTMs); chromatin; human disease
(This special issue belongs to the Section Molecular Genetics and Genomics)
Applications of Nanomaterials in the Antimicrobial Sector
edited by Ekaterina A. Obraztsova
submission deadline 30 Nov 2024 | 3 articles | Viewed by 3698 | Submission Open
Keywords: antimicrobial nanomaterials; nanostructured materials; nanoparticles; bioactive nanomaterials; nanomaterials contamination; antibacterial activity; antiviral activity; antibiotic resistance; food storage; environment
(This special issue belongs to the Section Molecular Microbiology)
Emerging Biotechnological Approaches for Natural Antiviral Molecules Discovery submission deadline 30 Nov 2024 | 2 articles | Viewed by 3650 | Submission Open
Keywords: natural antivirals; biotechnology; viruses; cellular signalling; natural bioactive compounds; viral infections; antiviral therapeutics; virus inhibition assays
(This special issue belongs to the Section Molecular Microbiology)
Molecular Research on Lung Cancer: Translational Perspectives
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 3602 | Submission Open
Keywords: lung cancer; oncogene; tumor microenvironment
(This special issue belongs to the Section Molecular Oncology)
Current Molecular Progress on Cell and Gene Therapies submission deadline 30 Nov 2024 | 2 articles | Viewed by 3599 | Submission Open
Keywords: gene therapy; cell therapy; gene delivery; gene editing; stem cells; regenerative medicine; CRISPR-Cas; viral vectors; non-viral vectors; immunotherapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Researches on Ischemic Stroke—2nd Edition
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 3444 | Submission Open
Keywords: ischemic stroke; molecular pathway; brain damage and neuronal death; excitotoxicity and apoptosis; inflammation; autophagy
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanisms and Therapeutic Targets in Skin Diseases
edited by Hanna Mys̈liwiec
submission deadline 30 Nov 2024 | 2 articles | Viewed by 3424 | Submission Open
Keywords: inflammatory skin diseases; systemic inflammation; infectious skin diseases; comorbidity; pathogenesis; cytokines
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Computational Approaches in Drug Design: Novel Methodologies and Applications
edited by
submission deadline 30 Nov 2024 | 3 articles | Viewed by 3317 | Submission Open
Keywords: drug design; computational approaches; molecular docking; molecular dynamics; pharmacophore modeling; homology modeling; computer aided drug design; ADME/Tox predictions; artificial intelligence
(This special issue belongs to the Section Molecular Informatics)
Molecular and Translational Research in Cardiovascular Endocrinology, Cardio-Metabolic Diseases and Non-alcoholic Fatty Liver Disease (NAFLD): 2nd Edition submission deadline 30 Nov 2024 | 4 articles | Viewed by 3217 | Submission Open
Keywords: cardiovascular endocrinology; atherosclerosis; coronary artery disease; endocrine hypertension; non-alcoholic fatty liver disease (NAFLD); diabetes mellitus and obesity; metabolic syndrome; endothelial cells; vascular inflammation; antidiabetic drugs; antihypertensive treatments; lipid lowering treatments; lifestyle interventions; molecular targeted therapies; heart failure; chronic kidney disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Gynecological Cancer: Targeted Therapeutics and Future Perspectives
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 3123 | Submission Open
Keywords:   molecular background;   precision medicine;   histomolecular diagnosis;   targeted therapies;   clinical trials;   overall survival;   disease-free survival;   gynecological cancer;   whole genomic assay;   molecular biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Insight into Microcirculation and Microvascular Diseases
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 3075 | Submission Open
Keywords: microcirculation; microangiopathy; vascular health; endothelial cells; resistance arteries; small vessels
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Bioactive Phenolics and Polyphenols 2024
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 3043 | Submission Open
Keywords: phenolic metabolism; biological activities; stability to food processing; elicitation; methods of analysis; dietary supplements; nutraceutical ingredients; non-thermal processing; extraction and purification
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Synthesis and Molecular Research of Drugs for Skin Diseases and Cosmetic Ingredients
edited by and Paulina Mucha
submission deadline 30 Nov 2024 | 2 articles | Viewed by 2879 | Submission Open
Keywords: skin diseases; skin cancers; aging; pathogenesis; topical dermatological therapy; systemic dermatological therapy; cosmetic ingredients; molecular mechanism; drugs design and synthesis; molecular mechanism
(This special issue belongs to the Section Molecular Pharmacology)
Harnessing Nature’s Potential: Plant-Derived Substances for Controlling Appetite and Promoting Weight Management
edited by and Ettore Novellino
submission deadline 30 Nov 2024 | 1 articles | Viewed by 2725 | Submission Open
Keywords: plant-derived substances; obesity; satiety control; weight management; gut hormones; bioactive compounds; energy metabolism; phytochemicals; molecular mechanisms; clinical trials
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Biomass-Derived Materials: Synthesis and Applications
edited by
submission deadline 30 Nov 2024 | 2 articles | Viewed by 2648 | Submission Open
Keywords: biomass; biomass-derived synthons; renewable chemicals; biopolymers; materials for water treatment; catalysts
(This special issue belongs to the Section Materials Science)
Current Molecular Science of Fragile X Syndrome and Associated Disorders
edited by Flora Tassone and Randi Hagerman
submission deadline 30 Nov 2024 | 2 articles | Viewed by 2616 | Submission Open
Keywords: FMR1; fragile X syndrome; FXPOI; FXTAS; FXAND; FXPAC; molecular studies
(This special issue belongs to the Section Molecular Biology)
Advances in Antibacterial Materials
edited by and Gabriela Graziani
submission deadline 30 Nov 2024 | 1 articles | Viewed by 2412 | Submission Open
Keywords: material functionalization; bioactive materials; antimicrobial; antibiofilm; metal coatings and nanoparticles; controlled release; biocompatibility
(This special issue belongs to the Section Materials Science)
The Inflammatory and Immune Response to Helicobacter pylori Infection
edited by Leonid B. Lazebnik and
submission deadline 30 Nov 2024 | 1 articles | Viewed by 2409 | Submission Open
Keywords: adhesion; antibiotics resistance; bacteriophages; chronic inflammation; dysbiosis; eradication; fucosylated glycan; gastric cancer; gastric microbiota; gut microbiota; Helicobacter pylori; H. pylori-associated gastritis; H. pylori differ stamms; host immune response; inflammasome; inflammatory response; innate immunity; Lewis system antigens; matrix metalloproteinases; microbial interaction; microbial metabolites; microRNA; molecular mimicry; non-coding RNA; oxidative stress; pathogen-associated molecular patterns; pattern recognition receptors; phytochemicals; postbiotics; probiotics; synthetic peptides; vaccine; virulence factors
(This special issue belongs to the Section Molecular Microbiology)
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