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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Pathogen Detection, Microdevice Technologies and AI-Driven Analysis

edited by

Younseong Song

submission deadline 20 Mar 2026 | 2 articles | Viewed by 2349 | Submission Open

Keywords: pathogen detection; microfluidic; microdevice; AI analysis; virus; bacteria; point-of-care testing; infectious disease; nanotechnology

(This special issue belongs to the Section Molecular Biology)

Bee Products and Their Flavonoids: Recent Advances in Molecular Mechanisms, Therapeutic Applications, and Innovative Delivery Systems

edited by

Nada Orsolic

and

Maja Jazvinšćak Jembrek

submission deadline 20 Mar 2026 | 1 articles | Viewed by 2267 | Submission Open

Keywords: honeybee products; flavonoids; bioactive compounds; biological activity; pharmacological activity; health benefits; side effects; disease prevention; antioxidant activity; apitherapy; nutritional properties; innovative technical approaches

(This special issue belongs to the Section Molecular Biology)

The Role of Lipids in Human Health

edited by

Angela Maria Rizzo

and Irma Colombo

submission deadline 20 Mar 2026 | 1 articles | Viewed by 2209 | Submission Open

Keywords: lipids; lipidomics; fatty acids; sphingolipids; steroids; metabolism

(This special issue belongs to the Section Biochemistry)

The Role of Macrophages in Tumors

edited by

Julia Kzhyshkowska

submission deadline 20 Mar 2026 | 1 articles | Viewed by 2172 | Submission Open

Keywords: tumor-associated macrophages; transcriptome; metabolome; epigenetics; angiogenesis; metastasis; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

Mechanisms and Effects of Endocrine Disruptors and Environmental Contaminants on Human Health

edited by

Margarida Lorigo

submission deadline 20 Mar 2026 | 1 articles | Viewed by 2159 | Submission Open

Keywords: environmental exposure; emerging compounds; human health; risk assessment; adverse outcome pathway; new approach methodologies; one health

(This special issue belongs to the Section Molecular Toxicology)

Vitamin D Signaling in Human Health and Diseases

edited by

Daniela Rovito

submission deadline 20 Mar 2026 | 2 articles | Viewed by 2108 | Submission Open

Keywords: vitamin D receptor; vitamin D; prevention; therapeutic potential; mineral homeostasis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetics and Omics in Autoimmune Diseases

edited by

Julian Ramírez-Bello

submission deadline 20 Mar 2026 | 5 articles | Viewed by 2106 | Submission Open

Keywords: autoimmune diseases; genetics; genomics; omics; single-nucleotide variants; copy number variants; variation; susceptibility; mRNAs; microRNAs; long non-coding RNAs; masive sequencing

(This special issue belongs to the Section Molecular Genetics and Genomics)

Mechanistic Insights into Pharmacological and Non-Pharmacological Pain Therapies: From Cellular Responses to Therapy Outcomes

edited by

Sungtae Koo

submission deadline 20 Mar 2026 | 1 articles | Viewed by 2086 | Submission Open

Keywords: neuromodulation; neural plasticity; glial activation; endogenous pain modulation; neuroinflammation; therapeutic mechanisms

(This special issue belongs to the Section Molecular Pharmacology)

Bioactive Phenolics and Polyphenols 2025

edited by

Davide Barreca

submission deadline 20 Mar 2026 | 2 articles | Viewed by 2081 | Submission Open

Keywords: phenolic metabolism; biological activities; stability to food processing; elicitation; methods of analysis; dietary supplements; nutraceutical ingredients; non-thermal processing; extraction and purification

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Bioactive Molecules from Food Waste in Food Packaging Applications

edited by

Jennifer Gubitosa

submission deadline 20 Mar 2026 | 1 articles | Viewed by 2070 | Submission Open

Keywords: wastes upcycling; waste management; circular economy; green chemistry; bioactive molecules; agri-food wastes and by-products; food packaging; active packaging

(This special issue belongs to the Section Materials Science)

Metabolic Regulators of Bone Health

edited by

Akkouch Adil

submission deadline 20 Mar 2026 | 1 articles | Viewed by 2020 | Submission Open

Keywords: bone; osteoporosis; diabetes; obesity; glucose; insulin; lipids; estrogen; microRNA; osteoblasts

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Insights into Transplantation and Machine Perfusion

edited by

Joan Roselló-Catafau

and

Arnau Panisello-Roselló

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1978 | Submission Open

Keywords: transplantation (liver; kidney; and other organs); primary failure; ischemia-reperfusion injury; static graft preservation; HOPE; NMP; cell signaling; glycocalyx; metabolomics; mitochondria; sterile inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research on Cancer Stem Cells

edited by

Ilze Štrumfa

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1970 | Submission Open

Keywords: cancer stem cells; tumour microenvironment; pancreatic cancer; glioblastoma; gastric cancer; breast cancer; lung cancer; colorectal cancer; renal cancer; liver cancer; melanoma; leukemia; lymphoma

(This special issue belongs to the Section Molecular Oncology)

Bioconjugates and Application

edited by

Gábor Mező

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1929 | Submission Open

Keywords: bioconjugates; targeted therapy; homing moieties; drug delivery; bioconjugates as diagnostic tools; targeted nanoparticles; antibody– drug conjugates; linkage systems

(This special issue belongs to the Section Macromolecules)

New Insights into Epilepsy: From Molecular Physiology to Pathology

edited by Paolo Mainardi

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1911 | Submission Open

Keywords: epilepsy; molecular pathology; disease; therapeutic strategies; celluar advance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Nanomedicines Against Bacterial Infections

edited by

Stephanie Andrade

, Nuno Guimarães,

Maria João Ramalho

and

Joana A. Loureiro

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1899 | Submission Open

Keywords: nanotechnology; nanoparticle; nanocarriers; nanoantibiotic; drug delivery system; targeted delivery; theranostic; infectious diseases; antibacterial agent; antimicrobial resistance; biomedical application

(This special issue belongs to the Section Molecular Nanoscience)

Novel Nanoparticle Composites: Functionalization and Application

edited by

Jovan M. Nedeljković

and

Vesna Lazić

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1877 | Submission Open

Keywords: nanoparticles; nanocomposites; synthesis; functionalization; interface; photocatalysis; antimicrobial nanoparticles; nanomedicine; theoretical modelling; computer simulations

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Molecular Research of Kidney Diseases

edited by Andrea Angioi

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1867 | Submission Open

Keywords: molecular genetics; kidney disease; biomarkers; cellular signaling; target therapeutics; innovative treatments

(This special issue belongs to the Section Molecular Biology)

Molecular Diagnosis and Targeted Therapies in Ischemic Stroke

edited by Alicia Aliena-Valero and María Castelló-Ruiz

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1830 | Submission Open

Keywords: ischemic stroke; cerebral protection; repair treatments; therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gene Function, Molecular Mechanisms, and Crop Breeding

edited by Hongwei Lu

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1777 | Submission Open

Keywords: molecular biology; gene function; molecular mechanism; crop breeding; molecular biology; agronomic traits; gene discovery; genomics; bioinfomatics; gene regulation

(This special issue belongs to the Section Molecular Plant Sciences)

Novel Statistical Methods in Gene Expression Analysis, Functional Genomics, Genetics, and Biochemistry

edited by Łukasz Huminiecki

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1734 | Submission Open

Keywords: multi-omics; statistics; gene expression analysis

(This special issue belongs to the Section Molecular Informatics)

Cotton Molecular Genomics and Genetics (Third Edition)

edited by

Jie Sun

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1707 | Submission Open

Keywords: cotton; biotic or abiotic stress; disease resistance; fiber yield and quality; gene editing; gene identification and function validation; genome-wide association study; QTL identification

(This special issue belongs to the Section Molecular Plant Sciences)

Green Chemical Pesticide Design, Synthesis and Evaluation

edited by Ranfeng Sun

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1695 | Submission Open

Keywords: green pesticides; natural products; action mechanism of pesticides; synthesis

(This special issue belongs to the Section Biochemistry)

Solanaceae Biology: From Genetics to Metabolism

edited by

Pengxiang Fan

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1664 | Submission Open

Keywords: Solanaceae; nightshade family; tomato; potato; tobacco; eggplant; genetics; metabolism; crop improvement; specialized metabolite

(This special issue belongs to the Section Molecular Plant Sciences)

Focus on the Tryptophan Pathway

edited by

Burkhard Poeggeler

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1638 | Submission Open

Keywords: aging; indole-3-propionic acid; kynurenic acid; melatonin; serotonin; tryptophan

(This special issue belongs to the Section Molecular Biology)

Nanostructures: From Synthesis, Modification to Biomedical Applications

edited by Kleoniki Giannousi and

Catherine Dendrinou-Samara

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1597 | Submission Open

Keywords: nanostructures; post-synthetic methods; multi-drug resistant bacteria; amyloidopathies; neurodegeneration; photocatalysis; biosensors

(This special issue belongs to the Section Molecular Nanoscience)

Gene Mutations in Cancer

edited by

Lucie Benešová

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1558 | Submission Open

Keywords: oncogenetics; somatic mutations; intratumor mutational heterogeneity; tumor mutational burden; circulating tumor DNA; liquid biopsy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Inflammatory Bowel Disease: Molecular Insights—2nd Edition

edited by

Belal Chami

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1543 | Submission Open

Keywords: genomic sequencing; microbiome; dysbiosis; commensal flora; omics; immunobiology; colitis; Crohn’ s disease; ulcerative colitis; multiomics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Microbial Natural Products

edited by Wenli Li

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1474 | Submission Open

Keywords: microbial natural products; biosynthetic gene clusters; structural elucidation; metabolic engineering; synthetic biology; bioactivity profiling; sustainable biomanufacturing

(This special issue belongs to the Section Molecular Microbiology)

Biological Barriers: Consciousness and Mental Illness

edited by

Adonis Sfera

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1425 | Submission Open

Keywords: cell membranes; transport protein regulation; blood– brain barrier; epithelial barriers; gut barrier; respiratory barriers; blood– saliva barrier; biological barriers and pathological changes; protection of biological barriers in diseases

(This special issue belongs to the Section Molecular Biology)

Cutting Edge Advances in Antitumor Properties of Natural Products

edited by

Francesca Giordano

and

Maria Luisa Panno

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1393 | Submission Open

Keywords: natural product; cancer; cell signaling; cell death and differentiation; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Functional Studies and Deep Phenotyping in Monogenic Forms of Diabetes, Severe Insulin Resistance and Hypoglycemia

edited by Fabrizio Barbetti

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1336 | Submission Open

Keywords: monogenic diabetes; neonatal diabetes mellitus; MODY; severe insulin resistance; insulin receptor; lipodystrophy; hyperinsulinemic hypoglycemia; ABCC8/KCNJ11 dominant forms of HH

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Studies of Hematologic Malignancies

edited by

Myunggon Ko

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1311 | Submission Open

Keywords: hematologic malignancies; molecular mechanisms; genetic and epigenetic aberrations; molecular diagnosis; targeted therapy and biomarkers

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Various Diseases and Drugs Involved in Vascular Tone Regulation in Cardiovascular Disease

edited by

Ju-Tae Sohn

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1297 | Submission Open

Keywords: vasoconstriction; vasodilation; calcium; protein kinase C; Rho-kinase; hypertension; nitric oxide

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Plant Breeding

edited by

Hélia Cardoso

, Sandra Correia and

Isaura Castro

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1245 | Submission Open

Keywords: plant breeding; proteomics; metabolomics; epigenomics; gene editing

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Drug Treatment in Alzheimer’s Disease

edited by

Roberto Dominici

and Diego Dolcetta

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1221 | Submission Open

Keywords: Alzheimer’ s disease (AD); glia; immune system; neurotoxicity; inflammation; beta-Amyloid (bA); neurofibrillary tangles (NFTs)

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Brain Plasticity

edited by

Beatrice Uguagliati

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1137 | Submission Open

Keywords: neurophysiology; neurobiology; synapses; synaptic plasticity; microglia; astrocytes; dendritic spines; neurodevelopment; neurodevelopmental disease; learning and memory; neuropharmacology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advancements in Novel Drug Delivery Systems for Gene and Drug Delivery

edited by

Rosamaria Pennisi

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1120 | Submission Open

Keywords: drug and gene delivery; novel drug delivery systems; nanoparticle-based delivery systems

(This special issue belongs to the Section Molecular Biology)

Microgravity, Cell Shape and Gene Expression: State of the Art, Challenges and Prospects

edited by Masahiro Terada

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1118 | Submission Open

Keywords: microgravity; space radiation; closed environment; space flight; parabolic flight; clinostat; human; rodent; microorganism; countermeasure; artificial gravity

(This special issue belongs to the Section Molecular Biology)

Peptide and Protein Metalation

edited by

Antonello Merlino

Irene Russo Krauss

and

Giarita Ferraro

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1088 | Submission Open

Keywords: metallodrugs; metal ions; metal complexes; metal– protein interaction; metal– peptide interaction

(This special issue belongs to the Section Biochemistry)

Oxygen Variations, 3rd Edition

edited by

Gerardo Bosco

Costantino Balestra

and

Simona Mrakic-Sposta

submission deadline 20 Mar 2026 | Viewed by 1016 | Submission Open

Keywords: hypoxia; hyperoxia; normoxia; biochemichal response; integrative approach; normo-hypo-hyperbaric; molecular research; gene expression; adaptive reactions; extreme environments

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into the Obstetrics and Gynecology

edited by

Gaspare Cucinella

submission deadline 20 Mar 2026 | Viewed by 1013 | Submission Open

Keywords: ginecology; pelvic disorders; endometrial; cervical and ovarian cancers; covid and pregnancy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic and Epigenetic Insights into Extracellular Vesicles

edited by

Dimitrios Vlachakis

and

George P. Chrousos

submission deadline 20 Mar 2026 | Viewed by 1007 | Submission Open

Keywords: exosomes; extracellular vesicles; cell– cell communication; endocrinology

(This special issue belongs to the Section Biochemistry)

Exploring Tolerance Mechanisms in Plants Under Stress

edited by

Lujun Yu

submission deadline 20 Mar 2026 | 1 articles | Viewed by 930 | Submission Open

Keywords: stress; tolerance; gene family; phytohormones; mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Genetic Mechanisms of Neurological Disorders

edited by

Patrícia Maciel

and Sara Duarte-Silva

submission deadline 20 Mar 2026 | 1 articles | Viewed by 910 | Submission Open

Keywords: neurodevelopmental disorders; neurodegenerative disorders; neuropsychiatric disorders; genetics; molecular biology; cellular models; animal models; pathogenesis; biomarkers; therapeutic targets; drug discovery; therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Functional Materials in Photocatalysis: From Design to Application

edited by

Miguel Díaz-Sánchez

submission deadline 20 Mar 2026 | 1 articles | Viewed by 866 | Submission Open

Keywords: nanostructured materials ; photocatalysis ; catalysis ; green synthesis ; material design ; surface engineering

(This special issue belongs to the Section Materials Science)

Current Research on Colloidal Emulsions: Preparation and Applications

edited by Alexander Djerdjev

submission deadline 20 Mar 2026 | 1 articles | Viewed by 866 | Submission Open

Keywords: emulsion formulation and stability; nano-; micro-; and high-internal-phase emulsions; drug delivery; aerogels; pickering emulsions; food emulsions; oil– water interface; surfactants; zeta potential at hydrophobic interfaces; advances in emulsion technology

(This special issue belongs to the Section Materials Science)

Advances in Plant Biotechnology: From Pathogen Diagnostics to Disease Management

edited by

Abdul Kader Jailani Amirudeen

submission deadline 20 Mar 2026 | 1 articles | Viewed by 842 | Submission Open

Keywords: plant pathogens; diagnostic; isothermal; biosensor; RNAi; CRISPRi; QTL mapping; GWAS; MAS or MABC

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Surfactant Systems: Thermodynamics, Molecular Interactions, and Applications

edited by

Mihalj Poša

submission deadline 20 Mar 2026 | 1 articles | Viewed by 784 | Submission Open

Keywords: micelles; mixed micelles; thermodynamic functions of micellization; micellar solubilization; enthalpy– entropy compensation; boundary surface; Langmuir isotherm; theoretical models

(This special issue belongs to the Section Biochemistry)

The Interaction Between Tumor Microenvironment and Cancer Stem Cell

edited by

Na Luo

submission deadline 20 Mar 2026 | 1 articles | Viewed by 779 | Submission Open

Keywords: tumor microenvironment; cancer stem cells; innate and adaptive immunity; mesenchymal stromal cells

(This special issue belongs to the Section Molecular Oncology)

Displaying special issue 901-950 on page 19 of 64.

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