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Microorganisms, Volume 10, Issue 8

2022 August - 208 articles

Cover Story: Chronic wounds, which respond poorly to treatment, are a major concern worldwide, affecting millions of patients every year. The microorganisms colonising the wound contribute to the establishment of chronicity through polymicrobial biofilm. Clinical management of chronic wounds relies on tissue debridement at regular intervals, which removes dead tissue, and the associated microbial communities, contributing to reorganize them. The complex network of species and interactions found in chronic wounds has the potential, through antagonist and/or synergistic crosstalk between different microorganisms, to accelerate or to impair wound healing. Understanding these interactions between microorganisms encountered in this clinical situation is essential to improve the management of chronic wounds. View this paper
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Articles (208)

  • Article
  • Open Access
2 Citations
2,743 Views
15 Pages

Loss of rpoE Encoding the δ-Factor of RNA Polymerase Impacts Pathophysiology of the Streptococcus pyogenes M1T1 Strain 5448

  • Joseph S. Rom,
  • Yoann Le Breton,
  • Emrul Islam,
  • Ashton T. Belew,
  • Najib M. El-Sayed and
  • Kevin S. McIver

Streptococcus pyogenes, also known as the Group A Streptococcus (GAS), is a Gram-positive bacterial pathogen of major clinical significance. Despite remaining relatively susceptible to conventional antimicrobial therapeutics, GAS still causes million...

  • Article
  • Open Access
5 Citations
3,366 Views
15 Pages

Herpesvirus Screening in Childhood Hematopoietic Transplant Reveals High Systemic Inflammation in Episodes of Multiple Viral Detection and an EBV Association with Elevated IL-1β, IL-8 and Graft-Versus-Host Disease

  • Moisés H. Rojas-Rechy,
  • Félix Gaytán-Morales,
  • Yessica Sánchez-Ponce,
  • Iván Castorena-Villa,
  • Briceida López-Martínez,
  • Israel Parra-Ortega,
  • María C. Escamilla-Núñez,
  • Alfonso Méndez-Tenorio,
  • Ericka N. Pompa-Mera and
  • Abigail Morales-Sánchez
  • + 2 authors

Infections remain a major cause of morbidity and mortality among hematopoietic stem cell transplant (HSCT) recipients. Unlike Epstein–Barr Virus (EBV) and Human Cytomegalovirus (HCMV), Human Herpesvirus (HHV) 6, HHV7 and HHV8 are not routinely...

  • Article
  • Open Access
25 Citations
4,030 Views
17 Pages

Evidence of Community-Wide Spread of Multi-Drug Resistant Escherichia coli in Young Children in Lusaka and Ndola Districts, Zambia

  • Flavien Nsoni Bumbangi,
  • Ann-Katrin Llarena,
  • Eystein Skjerve,
  • Bernard Mudenda Hang’ombe,
  • Prudence Mpundu,
  • Steward Mudenda,
  • Paulin Beya Mutombo and
  • John Bwalya Muma

Increased antimicrobial resistance (AMR) has been reported for pathogenic and commensal Escherichia coli (E. coli), hampering the treatment, and increasing the burden of infectious diarrhoeal diseases in children in developing countries. This study f...

  • Article
  • Open Access
23 Citations
4,291 Views
12 Pages

The Gene Expression Profile Differs in Growth Phases of the Bifidobacterium Longum Culture

  • Vladimir A. Veselovsky,
  • Marina S. Dyachkova,
  • Dmitry A. Bespiatykh,
  • Roman A. Yunes,
  • Egor A. Shitikov,
  • Polina S. Polyaeva,
  • Valeriy N. Danilenko,
  • Evgenii I. Olekhnovich and
  • Ksenia M. Klimina

To date, transcriptomics have been widely and successfully employed to study gene expression in different cell growth phases of bacteria. Since bifidobacteria represent a major component of the gut microbiota of a healthy human that is associated wit...

  • Article
  • Open Access
18 Citations
4,003 Views
18 Pages

Antifungal Activity and Plant Growth-Promoting Properties of Bacillus mojovensis B1302 against Rhizoctonia Cerealis

  • Yanjie Yi,
  • Pengyu Luan,
  • Kang Wang,
  • Guiling Li,
  • Yanan Yin,
  • Yanhui Yang,
  • Qingyao Zhang and
  • Yang Liu

Rhizoctonia cerealis is a worldwide soil-borne pathogenic fungus that significantly infects wheat and causes sharp eyespot in China. However, the biocontrol strains used for the control of Rhizoctonia cerealis are insufficient. In the present study,...

  • Communication
  • Open Access
7 Citations
2,768 Views
7 Pages

Phylogenomic Placement of American Southwest-Associated Clinical and Veterinary Isolates Expands Evidence for Distinct Cryptococcus gattii VGVI

  • Juan Monroy-Nieto,
  • Jolene R. Bowers,
  • Parker Montfort,
  • Guillermo Adame,
  • Constanza Giselle Taverna,
  • Hayley Yaglom,
  • Jane E. Sykes,
  • Shane Brady,
  • A. Brian Mochon and
  • David M. Engelthaler
  • + 2 authors

Whole-genome sequencing has advanced our understanding of the population structure of the pathogenic species complex Cryptococcus gattii, which has allowed for the phylogenomic specification of previously described major molecular type groupings...

  • Article
  • Open Access
16 Citations
4,353 Views
20 Pages

Effects of Light on Growth and Metabolism of Rhodococcus erythropolis

  • Selina Engelhart-Straub,
  • Philipp Cavelius,
  • Fabian Hölzl,
  • Martina Haack,
  • Dania Awad,
  • Thomas Brueck and
  • Norbert Mehlmer

Rhodococcus erythropolis is resilient to various stressors. However, the response of R. erythropolis towards light has not been evaluated. In this study, R. erythropolis was exposed to different wavelengths of light. Compared to non-illuminated contr...

  • Review
  • Open Access
14 Citations
4,586 Views
19 Pages

Virulence Characteristics and Distribution of the Pathogen Listeria ivanovii in the Environment and in Food

  • Franca Rossi,
  • Valerio Giaccone,
  • Giampaolo Colavita,
  • Carmela Amadoro,
  • Francesco Pomilio and
  • Paolo Catellani

Listeria ivanovii and L. monocytogenes, are the only pathogenic species of the genus Listeria and share many virulence factors and mechanisms of pathogenicity. L. ivanovii shows host tropism towards small ruminants and rodents and much lower virulenc...

  • Editorial
  • Open Access
10 Citations
2,544 Views
2 Pages

Plasmids Carrying Antimicrobial Resistance Genes in Gram-Negative Bacteria

  • Nadezhda K. Fursova,
  • Angelina A. Kislichkina and
  • Olga E. Khokhlova

Gram-negative bacteria are prevalent pathogens associated with hospital-acquired infections (HAI) that are a major challenge for patient safety, especially in intensive care units [...]

  • Article
  • Open Access
9 Citations
4,421 Views
13 Pages

Insights into the Bacterial Diversity and Detection of Opportunistic Pathogens in Mexican Chili Powder

  • Yoali Fernanda Hernández Gómez,
  • Jacqueline González Espinosa,
  • Miguel Ángel Ramos López,
  • Jackeline Lizzeta Arvizu Gómez,
  • Carlos Saldaña,
  • José Alberto Rodríguez Morales,
  • María Carlota García Gutiérrez,
  • Victor Pérez Moreno,
  • Erika Álvarez Hidalgo and
  • Juan Campos Guillén
  • + 3 authors

Chili powder is the most frequently consumed spice in Mexican diets. Thus, the dissemination of microorganisms associated with chili powder derived from Capsicum annuum L. is significant during microbial quality analysis, with special attention on de...

  • Article
  • Open Access
7 Citations
2,916 Views
14 Pages

Uninvited Guest: Arrival and Dissemination of Omicron Lineage SARS-CoV-2 in St. Petersburg, Russia

  • Anna Gladkikh,
  • Vladimir Dedkov,
  • Alena Sharova,
  • Ekaterina Klyuchnikova,
  • Valeriya Sbarzaglia,
  • Tatiana Arbuzova,
  • Majid Forghani,
  • Edward Ramsay,
  • Anna Dolgova and
  • Areg Totolian
  • + 2 authors

Following its emergence at the end of 2021, the Omicron SARS-CoV-2 variant rapidly spread around the world and became a dominant variant of concern (VOC). The appearance of the new strain provoked a new pandemic wave with record incidence rates. Here...

  • Article
  • Open Access
4 Citations
2,771 Views
18 Pages

In the present study, we investigated whether a non-invasive metabolic heat flux analysis could serve the determination of the functional traits in free-living saprotrophic decomposer fungi and aid the prediction of fungal influences on ecosystem pro...

  • Article
  • Open Access
5 Citations
2,217 Views
8 Pages

Phage vB_YenS_P400, a Novel Virulent Siphovirus of Yersinia enterocolitica Isolated from Deer

  • Jens A. Hammerl,
  • Andrea Barac,
  • Claudia Jäckel,
  • Julius Fuhrmann,
  • Ashish Gadicherla and
  • Stefan Hertwig

Phage vB_YenS_P400 isolated from deer, is a virulent siphovirus of Y. enterocolitica, whose circularly permutated genome (46,585 bp) is not substantially related to any other phage deposited in public nucleotide databases. vB_YenS_P400 showed a very...

  • Article
  • Open Access
9 Citations
5,457 Views
20 Pages

Unraveling the Genomic Potential of the Thermophilic Bacterium Anoxybacillus flavithermus from an Antarctic Geothermal Environment

  • Júnia Schultz,
  • Mariana Teixeira Dornelles Parise,
  • Doglas Parise,
  • Laenne G. Medeiros,
  • Thiago J. Sousa,
  • Rodrigo B. Kato,
  • Ana Paula Trovatti Uetanabaro,
  • Fabrício Araújo,
  • Rommel Thiago Jucá Ramos and
  • Alexandre S. Rosado
  • + 4 authors

Antarctica is a mosaic of extremes. It harbors active polar volcanoes, such as Deception Island, a marine stratovolcano having notable temperature gradients over very short distances, with the temperature reaching up to 100 °C near the fumaroles...

  • Article
  • Open Access
6 Citations
2,521 Views
19 Pages

Bioactives and Extracellular Enzymes Obtained from Fermented Macrofungi Cultivated in Cotton and Jatropha Seed Cakes

  • Joice Raísa Barbosa Cunha,
  • Daiana Wischral,
  • Ruben Darío Romero Pelaez,
  • Maria Aparecida de Jesus,
  • Ceci Sales-Campos,
  • Raquel Bombarda Campanha,
  • Thais Demarchi Mendes,
  • Simone Mendonça,
  • Eustáquio Souza Dias and
  • Félix Gonçalves de Siqueira

This work focused on obtaining fermented oil cake (cotton or Jatropha) via macrofungi growth with potential characteristics for animal feed formulations, such as the presence of extracellular enzymes, bioactive (ergosterol and antioxidants), and deto...

  • Article
  • Open Access
16 Citations
3,777 Views
16 Pages

The Association between Gut Microbiome Diversity and Composition and Heat Tolerance in Cattle

  • Xiaohui Zhang,
  • Ke Cui,
  • Xiaobo Wen,
  • Lianbin Li,
  • Xiangchun Yu,
  • Boling Li,
  • Haichao Lin,
  • Hongxuan He and
  • Fengyang Wang

Cattle are raised around the world and are frequently exposed to heat stress, whether in tropical countries or in regions with temperate climates. It is universally acknowledged that compared to those in temperate areas, the cattle breeds developed i...

  • Review
  • Open Access
13 Citations
4,792 Views
13 Pages

The microbiome is an essential part of most ecosystems. It was originally studied mostly through culturing but relatively few microbes can be cultured, so much of the microbiome was left unexplored. The emergence of metagenomic sequencing techniques...

  • Article
  • Open Access
23 Citations
4,212 Views
24 Pages

The microbial community of industrially produced Canadian Cheddar cheese was examined from curd to ripened cheese at 30–32 months using a combination of viable plate counts of SLAB (GM17) and NSLAB (MRSv), qPCR and 16S rRNA gene amplicon sequen...

  • Article
  • Open Access
12 Citations
4,122 Views
13 Pages

Bacterial Prevalence in Skin, Urine, Diarrheal Stool, and Respiratory Samples from Dogs

  • Dong-Chan Moon,
  • Ji-Hyun Choi,
  • Naila Boby,
  • Hee-Young Kang,
  • Su-Jeong Kim,
  • Hyun-Ju Song,
  • Ho-Sung Park,
  • Min-Chan Gil,
  • Soon-Seek Yoon and
  • Suk-Kyung Lim

The emergence of bacterial infections in companion animals is a growing concern as humans can also be infected through the transmission of pathogenic bacteria. Because there have been few studies conducted on companion animals, the extent and signifi...

  • Article
  • Open Access
9 Citations
3,526 Views
17 Pages

To determine whether rhizospheric and endophytic bacteria contribute to the ripening of pumpkins, an analysis was conducted on rhizospheric and endophytic bacteria and soil fertility in the rhizospheres of early and late-maturing pumpkin varieties. T...

  • Article
  • Open Access
9 Citations
2,534 Views
12 Pages

SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV

  • Daniel Kwakye Nomah,
  • Josep Maria Llibre,
  • Yesika Díaz,
  • Sergio Moreno,
  • Jordi Aceiton,
  • Andreu Bruguera,
  • Maria Gutiérrez-Macià,
  • Arkaitz Imaz,
  • Paula Suanzes and
  • the PISCIS Study Group
  • + 5 authors

People living with HIV (PLWH) are prioritised for SARS-CoV-2 vaccination due to their vulnerability to severe COVID-19. Therefore, the epidemiological surveillance of vaccination coverage and the timely identification of suboptimally vaccinated PLWH...

  • Correction
  • Open Access
1 Citations
1,660 Views
3 Pages

Correction: Ravin et al. Two New Species of Filamentous Sulfur Bacteria of the Genus Thiothrix, Thiothrix winogradskyi sp. nov. and ‘Candidatus Thiothrix sulfatifontis’ sp. nov. Microorganisms 2022, 10, 1300

  • Nikolai V. Ravin,
  • Simona Rossetti,
  • Alexey V. Beletsky,
  • Vitaly V. Kadnikov,
  • Tatyana S. Rudenko,
  • Dmitry D. Smolyakov,
  • Marina I. Moskvitina,
  • Maria V. Gureeva,
  • Andrey V. Mardanov and
  • Margarita Yu. Grabovich

The authors wish to make the following corrections to this paper [...]

  • Review
  • Open Access
25 Citations
7,153 Views
13 Pages

Many cite the strength of C–F bonds for the poor microbial biodegradability of polyfluorinated organic compounds (PFCs). However, commercial PFCs almost invariably contain more functionality than fluorine. The additional functionality provides...

  • Article
  • Open Access
26 Citations
3,742 Views
16 Pages

Spatio-Temporal Patterns of Ticks and Molecular Survey of Anaplasma marginale, with Notes on Their Phylogeny

  • Shumaila Alam,
  • Mehran Khan,
  • Abdulaziz Alouffi,
  • Mashal M. Almutairi,
  • Shafi Ullah,
  • Muhammad Numan,
  • Nabila Islam,
  • Zaibullah Khan,
  • Ome Aiman and
  • Abid Ali
  • + 2 authors

Hard ticks (Ixodida: Ixodidae) are medically important ectoparasites that feed on all classes of terrestrial vertebrates. Recently, we molecularly characterized hard ticks and associated Anaplasma spp. in the northern and central regions of Khyber Pa...

  • Article
  • Open Access
20 Citations
5,343 Views
20 Pages

Improved Cladocopium goreaui Genome Assembly Reveals Features of a Facultative Coral Symbiont and the Complex Evolutionary History of Dinoflagellate Genes

  • Yibi Chen,
  • Sarah Shah,
  • Katherine E. Dougan,
  • Madeleine J. H. van Oppen,
  • Debashish Bhattacharya and
  • Cheong Xin Chan

Dinoflagellates of the family Symbiodiniaceae are crucial photosymbionts in corals and other marine organisms. Of these, Cladocopium goreaui is one of the most dominant symbiont species in the Indo-Pacific. Here, we present an improved genome assembl...

  • Article
  • Open Access
16 Citations
4,274 Views
11 Pages

Molecular Evolution of the Pseudomonas aeruginosa DNA Gyrase gyrA Gene

  • Mitsuru Sada,
  • Hirokazu Kimura,
  • Norika Nagasawa,
  • Mao Akagawa,
  • Kaori Okayama,
  • Tatsuya Shirai,
  • Soyoka Sunagawa,
  • Ryusuke Kimura,
  • Takeshi Saraya and
  • Koichi Murakami
  • + 9 authors

DNA gyrase plays important roles in genome replication in various bacteria, including Pseudomonasaeruginosa. The gyrA gene encodes the gyrase subunit A protein (GyrA). Mutations in GyrA are associated with resistance to quinolone-based antibiotics. W...

  • Review
  • Open Access
7 Citations
3,567 Views
11 Pages

The genus Iodidimonas was recently proposed in the class Alphaproteobacteria. Iodidimonas strains are aerobic, mesophilic, neutrophilic, moderately halophilic, and chemo-organotrophic. They were first discovered in natural gas brine water containing...

  • Review
  • Open Access
20 Citations
9,907 Views
18 Pages

Anti-Toxoplasma gondii IgM Long Persistence: What Are the Underlying Mechanisms?

  • José Antonio Vargas-Villavicencio,
  • Irma Cañedo-Solares and
  • Dolores Correa

Diagnosis of Toxoplasma gondii acute infection was first attempted by detection of specific IgM antibodies, as for other infectious diseases. However, it was noted that this immunoglobulin declines slowly and may last for months or even years. Apart...

  • Article
  • Open Access
20 Citations
4,019 Views
14 Pages

Machine Learning Algorithms for Classification of MALDI-TOF MS Spectra from Phylogenetically Closely Related Species Brucella melitensis, Brucella abortus and Brucella suis

  • Flavia Dematheis,
  • Mathias C. Walter,
  • Daniel Lang,
  • Markus Antwerpen,
  • Holger C. Scholz,
  • Marie-Theres Pfalzgraf,
  • Enrico Mantel,
  • Christin Hinz,
  • Roman Wölfel and
  • Sabine Zange

(1) Background: MALDI-TOF mass spectrometry (MS) is the gold standard for microbial fingerprinting, however, for phylogenetically closely related species, the resolution power drops down to the genus level. In this study, we analyzed MALDI-TOF spectr...

  • Review
  • Open Access
8 Citations
4,378 Views
20 Pages

To Die or Not to Die—Regulated Cell Death and Survival in Cyanobacteria

  • Natasha S. Barteneva,
  • Ayagoz Meirkhanova,
  • Dmitry Malashenkov and
  • Ivan A. Vorobjev

Regulated cell death (RCD) is central to the development, integrity, and functionality of multicellular organisms. In the last decade, evidence has accumulated that RCD is a universal phenomenon in all life domains. Cyanobacteria are of specific inte...

  • Article
  • Open Access
12 Citations
4,396 Views
14 Pages

Screening of Healthy Feral Pigeons (Columba livia domestica) in the City of Zurich Reveals Continuous Circulation of Pigeon Paramyxovirus-1 and a Serious Threat of Transmission to Domestic Poultry

  • Désirée Annaheim,
  • Barbara Renate Vogler,
  • Brigitte Sigrist,
  • Andrea Vögtlin,
  • Daniela Hüssy,
  • Christian Breitler,
  • Sonja Hartnack,
  • Christian Grund,
  • Jacqueline King and
  • Sarah Albini
  • + 1 author

Pigeon paramyxovirus-1 (PPMV-1) is predominantly isolated from pigeons or doves and forms a separate group of viral strains within Avian Orthoavulavirus-1, the causative agent of Newcastle disease in poultry. Since the introduction of PPMV-1 into Eur...

  • Article
  • Open Access
8 Citations
4,231 Views
20 Pages

Phytoplankton Responses to Bacterially Regenerated Iron in a Southern Ocean Eddy

  • Marion Fourquez,
  • Robert F. Strzepek,
  • Michael J. Ellwood,
  • Christel Hassler,
  • Damien Cabanes,
  • Sam Eggins,
  • Imojen Pearce,
  • Stacy Deppeler,
  • Thomas W. Trull and
  • Matthieu Bressac
  • + 1 author

In the Subantarctic sector of the Southern Ocean, vertical entrainment of iron (Fe) triggers the seasonal productivity cycle but diminishing physical supply during the spring to summer transition forces microbial assemblages to rapidly acclimate. Her...

  • Article
  • Open Access
2 Citations
2,670 Views
18 Pages

Pedobacter cryoconitis BG5 is an obligate psychrophilic bacterium that was first isolated on King George Island, Antarctica. Over the last 50 years, the West Antarctic, including King George Island, has been one of the most rapidly warming places on...

  • Article
  • Open Access
9 Citations
3,868 Views
16 Pages

Soil Metabolomics Predict Microbial Taxa as Biomarkers of Moisture Status in Soils from a Tidal Wetland

  • Taniya RoyChowdhury,
  • Lisa M. Bramer,
  • Joseph Brown,
  • Young-Mo Kim,
  • Erika Zink,
  • Thomas O. Metz,
  • Lee Ann McCue,
  • Heida L. Diefenderfer and
  • Vanessa Bailey

We present observations from a laboratory-controlled study on the impacts of extreme wetting and drying on a wetland soil microbiome. Our approach was to experimentally challenge the soil microbiome to understand impacts on anaerobic carbon cycling p...

  • Review
  • Open Access
5 Citations
3,196 Views
18 Pages

Antimicrobial Use and Resistance in Surplus Dairy Calf Production Systems

  • Poonam G. Vinayamohan,
  • Samantha R. Locke,
  • Rafael Portillo-Gonzalez,
  • David L. Renaud and
  • Gregory G. Habing

Surplus calves, which consist predominately of male calves born on dairy farms, are an underrecognized source of antimicrobial-resistant (AMR) pathogens. Current production systems for surplus calves have important risk factors for the dissemination...

  • Commentary
  • Open Access
23 Citations
7,384 Views
12 Pages

Babesia, Theileria, Plasmodium and Hemoglobin

  • Daniel Sojka,
  • Marie Jalovecká and
  • Jan Perner

The Propagation of Plasmodium spp. and Babesia/Theileria spp. vertebrate blood stages relies on the mediated acquisition of nutrients available within the host’s red blood cell (RBC). The cellular processes of uptake, trafficking and metabolic...

  • Article
  • Open Access
5 Citations
3,884 Views
19 Pages

Molecular Epidemiology of Penicillin-Susceptible Staphylococcus aureus Bacteremia in Australia and Reliability of Diagnostic Phenotypic Susceptibility Methods to Detect Penicillin Susceptibility

  • Geoffrey W. Coombs,
  • Nicholas W. T. Yee,
  • Denise Daley,
  • Catherine M. Bennett,
  • James O. Robinson,
  • Marc Stegger,
  • Princy Shoby and
  • Shakeel Mowlaboccus

Background: Defined by the emergence of antibiotic resistant strains, Staphylococcus aureus is a priority bacterial species with high antibiotic resistance. However, a rise in the prevalence of penicillin-susceptible S. aureus (PSSA) bloodstream infe...

  • Review
  • Open Access
17 Citations
8,730 Views
14 Pages

Cutibacterium acnes (C. acnes, formerly Propionibacterium acnes) is considered to be a non-pathogenic resident of the human skin, as well as mucosal surfaces. However, it also has been demonstrated that C. acnes plays a pathogenic role in diseases su...

  • Article
  • Open Access
19 Citations
3,340 Views
28 Pages

Lycium ruthenicum, a halophytic shrub, has been used to remediate saline soils in northwest China. However, little is known about its root-associated microbial community and how it may be affected by the plant’s growth cycle. In this study, we...

  • Article
  • Open Access
3 Citations
3,190 Views
15 Pages

Validation studies conducted within a food processing facility using surrogate organisms could better represent the manufacturing process than controlled laboratory studies with pathogenic bacteria on precision equipment in a BSL-2 lab. The objective...

  • Article
  • Open Access
3 Citations
2,861 Views
13 Pages

Co-Infection of L. monocytogenes and Toxoplasma gondii in a Sheep Flock Causing Abortion and Lamb Deaths

  • Maria Elisabetta De Angelis,
  • Camillo Martino,
  • Alexandra Chiaverini,
  • Chiara Di Pancrazio,
  • Violeta Di Marzio,
  • Serena Bosica,
  • Daniela Malatesta,
  • Stefania Salucci,
  • Nadia Sulli and
  • Francesco Pomilio
  • + 1 author

Abortion in livestock is a public health burden, and the cause of economic losses for farmers. Abortion can be multifactorial, and a deep diagnostic investigation is important to reduce the spread of zoonotic disease and public health prevention. In...

  • Article
  • Open Access
2 Citations
5,055 Views
11 Pages

Vaginal Leptothrix: An Innocent Bystander?

  • Pedro Vieira-Baptista,
  • Joana Lima-Silva,
  • Mario Preti,
  • Carlos Sousa,
  • Fernanda Caiano,
  • Colleen K. Stockdale and
  • Jacob Bornstein

Leptothrix are long bacteria of rare occurrence; although these bacteria have been implicated in causing vaginal symptoms identical to candidiasis, studies on prevalence and effect on overall vaginal health are lacking. In this study, we evaluated da...

  • Article
  • Open Access
9 Citations
3,082 Views
13 Pages

Transcriptomic Differences between Free-Living and Parasitic Chilodonella uncinata (Alveolata, Ciliophora)

  • Xialian Bu,
  • Weishan Zhao,
  • Ming Li,
  • Wenxiang Li,
  • Shangong Wu,
  • Hong Zou and
  • Guitang Wang

Chilodonella uncinata is a facultatively parasitic ciliate, which can opportunistically parasitize on fish gills and fins, and sometimes even cause host mortality. Previous molecular studies of C. uncinata mainly focused on genetic diversity and mole...

  • Article
  • Open Access
3 Citations
2,360 Views
14 Pages

Titanium dioxide nanoparticle (TiO2 NP) toxicity to the growth of organisms has been gradually clarified; however, its effects on microorganism-mediated phosphorus turnover are poorly understood. To evaluate the influences of TiO2 NPs on phosphorus f...

  • Article
  • Open Access
3 Citations
2,664 Views
10 Pages

Efficacy of Off-Label Anti-Amoebic Agents to Suppress Trophozoite Formation of Acanthamoeba spp. on Non-Nutrient Agar Escherichia Coli Plates

  • Vithusan Muthukumar,
  • Lei Shi,
  • Ning Chai,
  • Achim Langenbucher,
  • Sören L. Becker,
  • Berthold Seitz,
  • Erika Orosz,
  • Tanja Stachon,
  • Albrecht F. Kiderlen and
  • Nóra Szentmáry
  • + 1 author

Acanthamoeba keratitis (AK) is a dangerous infectious disease, which is associated with a high risk of blindness for the infected patient, and for which no standard therapy exists thus far. Patients suffering from AK are thus treated, out of necessit...

  • Article
  • Open Access
8 Citations
4,958 Views
10 Pages

Combined Orthoplastic Approach in Fracture-Related Infections of the Distal Tibia

  • Andrea Sambri,
  • Marco Pignatti,
  • Sara Tedeschi,
  • Maria Elisa Lozano Miralles,
  • Claudio Giannini,
  • Michele Fiore,
  • Matteo Filippini,
  • Riccardo Cipriani,
  • Pierluigi Viale and
  • Massimiliano De Paolis

This series reports on the treatment of distal tibia (DT) fracture-related infections (FRI) with a combined orthoplastic approach. Thirteen patients were included. In eight patients with extensive bone involvement and in those with a non-healed fract...

  • Article
  • Open Access
5 Citations
6,100 Views
27 Pages

Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19

  • Frauke Assmus,
  • Jean-Sélim Driouich,
  • Rana Abdelnabi,
  • Laura Vangeel,
  • Franck Touret,
  • Ayorinde Adehin,
  • Palang Chotsiri,
  • Maxime Cochin,
  • Caroline S. Foo and
  • Eric Chatelain
  • + 21 authors

In the absence of drugs to treat or prevent COVID-19, drug repurposing can be a valuable strategy. Despite a substantial number of clinical trials, drug repurposing did not deliver on its promise. While success was observed with some repurposed drugs...

  • Article
  • Open Access
10 Citations
3,733 Views
10 Pages

Role of Intracellular Pulmonary Pathogens during SARS-CoV-2 Infection in the First Pandemic Wave of COVID-19: Clinical and Prognostic Significance in a Case Series of 1200 Patients

  • Matteo Guarino,
  • Benedetta Perna,
  • Francesca Cuoghi,
  • Michele Domenico Spampinato,
  • Alice Eleonora Cesaro,
  • Francesca Manza,
  • Adriana Pretula,
  • Anastasio Grilli,
  • Martina Maritati and
  • Carlo Contini
  • + 4 authors

Background: Since 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic (COVID-19) has caused millions of deaths worldwide and is the second most serious pandemic after the Spanish flu. Despite SARS-CoV-2 infection having a...

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Microorganisms - ISSN 2076-2607