Mechanisms of Tumor Immune Evasion
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Immunology and Immunotherapy".
Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 98265
Special Issue Editors
Interests: immunotherapy, monoclonal antibodies, immunometabolism
Interests: B cell malignancies, metabolism, oxidative stress, targeted therapy, immunooncology
Special Issue Information
Dear Colleagues,
The immune system can mount a response against malignant cells. However, in advanced cancer, the effectiveness of this response is usually insufficient. Developing cancer escapes immune surveillance and shapes the microenvironment to support tumor development and progression. Anticancer immunotherapy has emerged in recent years as a forefront strategy to combat a range of malignancies with long-lasting clinical benefits. Most of the currently available anticancer immunotherapies enhance the ability of the immune system to recognize and attack tumor cells. However, despite spectacular clinical responses in some patients, an array of mechanisms that allow cancer cells to block the immune system constitute a key barrier to effective immunotherapy in large cohorts of patients. Therefore, identification and validation of tumor immune evasion mechanisms have become pressing subjects in the field of antitumor immunotherapy.
This Special Issue will highlight recent discoveries on various strategies used by tumor cells to escape the host immune system. The goal is to gather cutting-edge research, current views, and new insights that will help not only to understand these mechanisms but will also pave the way for modern therapeutic strategies that enhance the natural antitumor responses of the immune system.
We look forward to your contributions.
Dr. Magdalena Winiarska
Dr. Malgorzata Firczuk
Dr. Radoslaw Zagozdzon
Guest Editors
Manuscript Submission Information
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Keywords
- immunotherapy
- immunosurveillance
- tumor, immune system
- tumor microenvironment
- immune suppression
- resistance
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