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The Effect of Bioactive Compounds in Anti-inflammation

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: 15 December 2024 | Viewed by 2102

Special Issue Editor


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Guest Editor
Department of Human Nutrition and Dietetics, Faculty of Food Technology, University of Agriculture, 30-149 Krakow, Poland
Interests: human nutrition; antioxidant and anti-inflammatory properties; plant food
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Bioactive food ingredients are understood as compounds that can enhance, weaken, or modify the body’s physiological and metabolic functions. The effects of such ingredients may be beneficial or unfavorable. The use of research strategies such as genomics, proteomics, and metabolomics, as well as access to large amounts of data (e.g., collected in databases) and tools for their processing, provide unprecedented expansion possibilities with regard to knowledge about bioactive food ingredients.

Chronic inflammation is a symptom accompanying many non-communicable diseases. It seems reasonable to create and use an anti-inflammatory dietary pattern in the prevention and treatment of these diseases. It is a known fact that food can influence the body's inflammation through immunomodulation. Various foods or nutritional and bioactive food ingredients may have pro- or anti-inflammatory effects. However, it is the overall diet that has the greatest impact on the functioning of the body. An anti-inflammatory diet therefore includes both many food components and food products with anti-inflammatory potential, and eliminates or recommends limiting the consumption of pro-inflammatory foods. It is considered particularly important when planning a diet to take into account the large supply of raw materials and plant products. The combination of these strategies allows for a cumulative positive effect of the diet on reducing inflammation in the body and thus reducing the risk of the occurrence or severity of lifestyle diseases.

Dr. Ewa Piątkowska
Guest Editor

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Keywords

  • inflammation
  • plant origin food
  • antioxidants
  • human health
  • non-communicable diseases

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Published Papers (1 paper)

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Review

35 pages, 2745 KiB  
Review
Potential Application of Plant-Derived Compounds in Multiple Sclerosis Management
by Seth Woodfin, Sierra Hall, Alexis Ramerth, Brooke Chapple, Dane Fausnacht, William Moore, Hana Alkhalidy and Dongmin Liu
Nutrients 2024, 16(17), 2996; https://doi.org/10.3390/nu16172996 - 5 Sep 2024
Viewed by 1678
Abstract
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurodegeneration, resulting in significant disability and reduced quality of life. Current therapeutic strategies primarily target immune dysregulation, but limitations in efficacy and tolerability highlight the need for alternative treatments. Plant-derived [...] Read more.
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurodegeneration, resulting in significant disability and reduced quality of life. Current therapeutic strategies primarily target immune dysregulation, but limitations in efficacy and tolerability highlight the need for alternative treatments. Plant-derived compounds, including alkaloids, phenylpropanoids, and terpenoids, have demonstrated anti-inflammatory effects in both preclinical and clinical studies. By modulating immune responses and promoting neuroregeneration, these compounds offer potential as novel adjunctive therapies for MS. This review provides insights into the molecular and cellular basis of MS pathogenesis, emphasizing the role of inflammation in disease progression. It critically evaluates emerging evidence supporting the use of plant-derived compounds to attenuate inflammation and MS symptomology. In addition, we provide a comprehensive source of information detailing the known mechanisms of action and assessing the clinical potential of plant-derived compounds in the context of MS pathogenesis, with a focus on their anti-inflammatory and neuroprotective properties. Full article
(This article belongs to the Special Issue The Effect of Bioactive Compounds in Anti-inflammation)
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