Physical Exercise Impacts on Human Physical and Psychological Health

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Healthcare healthcare	2.4	3.5	2013	20.3 Days	CHF 2700	Submit
Hygiene hygiene	-	-	2021	19.2 Days	CHF 1000	Submit
Journal of Clinical Medicine jcm	3.0	5.7	2012	16 Days	CHF 2600	Submit
Life life	3.2	4.3	2011	17.8 Days	CHF 2600	Submit
Sports sports	2.2	4.1	2013	19.1 Days	CHF 1800	Submit

12 pages, 1206 KiB

Open AccessArticle

The Impact of Isotonic Seawater on Subjective and Objective Nose Patency in Athletes: A Randomized Controlled Trial

by Andro Košec, Tomislav Vlahović, Branko Šilović, Mislav Rakić, Ana Starešinić and Vedrana Aljinović-Vučić

J. Clin. Med. 2025, 14(8), 2742; https://doi.org/10.3390/jcm14082742 - 16 Apr 2025

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Abstract

Background/Objectives: Nasal irrigation with isotonic seawater is a known and oft-used treatment for nasal obstruction in patients with acute and chronic nasal inflammatory disease undergoing therapy with intranasal corticosteroids and antihistamine drugs. Nasal patency in healthy athletes is extremely important; however, to date, [...] Read more.

Background/Objectives: Nasal irrigation with isotonic seawater is a known and oft-used treatment for nasal obstruction in patients with acute and chronic nasal inflammatory disease undergoing therapy with intranasal corticosteroids and antihistamine drugs. Nasal patency in healthy athletes is extremely important; however, to date, the effect of isotonic solutions for nasal irrigation in healthy athletes has not been tested. This randomized controlled trial aimed to investigate the potential synergy of physical exercise and nasal isotonic seawater on airflow and the subjective assessment of nasal patency in healthy, high-level athletes. Methods: The intervention group included 33 healthy athletes who used an isotonic seawater nasal spray daily, with a control group including 31 healthy athletes who did not use any sprays; both groups underwent identical seven-day training periods. The primary outcome measures were subjective NOSE questionnaire scores and secondary peak nasal inspiratory flow (PNIF) measures, while anthropometric and demographic variables were covariates. Results: A significant decrease in subjective nasal resistance scores was observed in the intervention group compared to the control group (binary logistic regression model, p = 0.006, RR 7.695), both in the first and second measurement interval. This effect increased with time (Friedman’s two-way analysis of variance, p < 0.001). Peak nasal inspiratory flow is positively affected by exercise but not by isotonic seawater spray intervention. Conclusions: The effects of nasal isotonic seawater irrigation during intense athletic training are beneficial on subjective nasal patency in the short term, while the effects on objective nasal patency are less clear. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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21 pages, 3647 KiB

Open AccessArticle

Systemic Responses Towards Oxy-Inflammation, Hormones, and Mood in Breast Cancer Survivors: Preliminary Evidences from Dragon Boat Endurance Race

by Michela Montorsi, Alessandra Vezzoli, Federica Mrakic Sposta, Maristella Gussoni, Andrea Brizzolari, Gerardo Bosco, Cinzia Dellanoce, Alessandra Barassi, Barbara Picconi, Cristina Ranuncoli and Simona Mrakic Sposta

J. Clin. Med. 2025, 14(7), 2532; https://doi.org/10.3390/jcm14072532 - 7 Apr 2025

Viewed by 588

Abstract

Background/Objectives: Endurance exercise increases oxygen demand and, when not balanced by antioxidant defenses, consequently, oxidative stress and inflammatory cytokines increase too. In breast cancer survivors (BCS), post-treatment, physical capacity decreases, lowering life quality. Dragon boat (DB) paddling has shown benefits in reducing lymphedema [...] Read more.

Background/Objectives: Endurance exercise increases oxygen demand and, when not balanced by antioxidant defenses, consequently, oxidative stress and inflammatory cytokines increase too. In breast cancer survivors (BCS), post-treatment, physical capacity decreases, lowering life quality. Dragon boat (DB) paddling has shown benefits in reducing lymphedema and improving psychological well-being. This study aimed at non-invasively investigating in BCS, by means of saliva and urine samples, the systemic responses to oxy-inflammation, and appetite hormones after a DB endurance race. Methods: 15 BCS and 15 healthy women (5 (CTR) who performed the DB race too) were studied. BCS and CTR were monitored pre- and post-race. Reactive oxygen species (ROS) production, total antioxidant capacity (TAC), lipid peroxidation (8-iso), DNA oxidation (8-OH-dG), nitric oxide metabolites (NOx), inflammation markers (IL-6-10 and TNFα), appetite hormones, electrolytes concentration, psychometric, and physical scales were assessed. Results: At rest, compared to healthy women, BCS showed a significant increase in oxy-inflammation biomarkers. BCS showed a general increase in oxy-inflammation parameters compared to CTR after the DB race. In BCS, there were the following results: ROS: +80%; lipid peroxidation: +103%; DNA oxidation: +44%; interleukins-6: +179%; IL-10: +55%; TNFα: +9%, NOx: +60% increases and unbalanced appetite hormones: leptin (−32%); and ghrelin (+53%). Moreover, the dragon boat offered a holistic approach to recovery, addressing emotional and social needs supporting belonging, love, and esteem needs, reported to be about 56% of the motivations in this activity, while post-race the following increased: a sense of fatigue (+55%); tiredness (48%); a cold sensation (+15%); and +32% pain. Conclusions: This study provided evidence that, in BCS, a DB endurance race produces an important imbalance in the oxy-inflammation state, at the same time being accompanied by a positive impact on subjective mood and general wellness. Future studies should focus on long-term effects. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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11 pages, 992 KiB

Open AccessArticle

Beyond the Handicap: A Cross-Sectional Study of Mental Health Amongst Registered Golfers in Spain

by P. Martín-Escudero, M. Fuentes-Ferrer, F. Peinado Miguel and E. Jiménez-Herranz

Sports 2025, 13(3), 80; https://doi.org/10.3390/sports13030080 - 7 Mar 2025

Viewed by 729

Abstract

The prevalence of impaired mental health (MH) has increased in recent decades. The aim of the study was to analyze the prevalence of impaired MH amongst registered Spanish golfers using the GHQ-28 questionnaire. A cross-sectional online survey was carried out in Spain between [...] Read more.

The prevalence of impaired mental health (MH) has increased in recent decades. The aim of the study was to analyze the prevalence of impaired MH amongst registered Spanish golfers using the GHQ-28 questionnaire. A cross-sectional online survey was carried out in Spain between March and August 2024 using a self-administered questionnaire on 298 adult participants. The participants were mainly men (75.1%) over 60 years of age (50.7%) who were married or with a partner (79.5%), and who were active in the job market (56%). Of the participants, 73.5% reported an improvement in MH levels attributed to the game, and 77.2% recommended golf as a way to improve MH. The prevalence of impaired MH was 6.7% (95% confidence interval [CI]: 4.1–10.2%). Differences in impaired MH were found according to age (<=45 years: 28.6%; 46–60 years: 5.0% and >60 years: 4.0%; p = 0.001), marital status (married or with a partner: 4.6% vs. other: 14.8%; p = 0.009) and time of play (morning: 3.3% vs. other: 10.3%; p = 0.015). The prevalence of impaired MH detected was low and these results indicated that such playing habits and characteristics may have a positive impact on the mental wellbeing of golf players. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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13 pages, 233 KiB

Open AccessReview

The Health Effects of Karate Training: A Review of 21st Century Research

by Paweł Adam Piepiora

Healthcare 2025, 13(2), 118; https://doi.org/10.3390/healthcare13020118 - 9 Jan 2025

Viewed by 1376

Abstract

Background/Objectives: To date, the health effects of karate have not been identified. Therefore, the aim of this article is to learn more about the health effects of karate training based on a review of current research. Methods: The Scopus database was searched from [...] Read more.

Background/Objectives: To date, the health effects of karate have not been identified. Therefore, the aim of this article is to learn more about the health effects of karate training based on a review of current research. Methods: The Scopus database was searched from 2000 onwards for available articles related only to karate. The following intermediate phrases were not included: combat sport, fighting art, hand-to-hand combat, martial art, and self-defence system. The filter used was desk review analysis. Only 14 scientific articles (research papers and review papers) strictly on karate were found. The method of source material analysis and critical analysis of the source text was then used. Results: It was shown that kumite appears to require significantly more metabolic power than kata. Furthermore, the greater skill of karatekas is associated with their greater physical fitness, and long-term karate training attenuates the decline in dynamic visual acuity (DVA). The role of modified and individualised forms of karate training is also highlighted as important for the health of practitioners. Furthermore, long-term karate practice is associated with extensive modulation of immunological parameters. Karate training can also significantly improve motor skills. It can also play an important role in the development of willpower and personality traits that contribute to the well-being of its practitioners. Furthermore, nutritional and psychological interventions combined with karate training may improve cardiometabolic parameters, oxidative stress and inflammation. Karate training may also contribute to the prevention of osteoporosis and strengthen the left ventricular myocardium. Conclusions: It was found that there is a paucity of contemporary research on the health effects of karate training. In addition, they are limited to the individuals studied, so that generalisations about these effects in the general population of karate practitioners cannot be made. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

18 pages, 2591 KiB

Open AccessSystematic Review

Effect of Aerobic Exercise on Blood Glucose Among Those with Prediabetes: A Systematic Review and Meta-Analysis

by Tianyi Jiang, Zichen Ye, Qu Lu, Peixia Cheng and Qi Gao

Life 2025, 15(1), 32; https://doi.org/10.3390/life15010032 - 30 Dec 2024

Viewed by 889

Abstract

Prediabetes, a state between normoglycemia and diabetes, is increasingly affecting population health; thus, it should not be overlooked. This systematic review and meta-analysis aimed to explore the efficacy of aerobic exercise on blood glucose indicators among those with prediabetes. Five databases, including PubMed, [...] Read more.

Prediabetes, a state between normoglycemia and diabetes, is increasingly affecting population health; thus, it should not be overlooked. This systematic review and meta-analysis aimed to explore the efficacy of aerobic exercise on blood glucose indicators among those with prediabetes. Five databases, including PubMed, Embase, the Cochrane Library, Web of Science, and CINAHL, were searched up to September 2024 to identify randomized controlled trials measuring the effect of aerobic exercise on blood glucose levels among individuals with prediabetes. Data on fasting blood glucose (FBG), 2-h postprandial plasma glucose (2hPG), and hemoglobin A1c (HbA1c) were extracted. Subgroup analyses were conducted based on intervention duration, weekly exercise duration, and volume. In total, 2518 relevant records were initially retrieved, and 16 studies were included in this systematic review, with 14 providing sufficient data for meta-analysis. Compared to the control group, the weighted mean difference (MD) for FBG, 2hPG, and HbA1c was −1.33 (95%CI: −1.87, −0.89), −1.00 (95%CI: −1.60, −0.39), and −1.05 (95%CI: −1.49, −0.61), respectively. Subgroup analysis showed that pooled effect size for FBG, 2hPG, and HbA1c was greater in the subgroup subjected to ≥48 weeks of intervention compared to the subgroup subjected to ≤24 weeks of intervention, although only the difference in FBG was significant (p < 0.05). Weekly exercise longer than 180 min/week led to greater reductions in FBG, 2hPG, and HbA1c compared to weekly exercise shorter than 150 min/week, and only differences in 2hPG were not significant (p > 0.05). Total weekly exercise of 1314–1323 MET·min/week led to greater reductions in FBG and HbA1c levels compared to 975–1080 MET·min/week (p > 0.05). Aerobic exercise effectively decreases FBG, 2hPG, and HbA1c and controls blood glucose levels. The volume and duration of aerobic exercise are important factors affecting the reduction in blood glucose levels, exhibiting a positive correlation within a specific range. Aerobic exercise can serve as a viable therapeutic approach for reducing the risk of diabetes among individuals with prediabetes. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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17 pages, 1567 KiB

Open AccessArticle

A Pilot Study on the Effects of Exercise Training on Cardiorespiratory Performance, Quality of Life, and Immunologic Variables in Long COVID

by Asghar Abbasi, Chiara Gattoni, Michelina Iacovino, Carrie Ferguson, Jacqueline Tosolini, Ashrita Singh, Kyaw Khaing Soe, Janos Porszasz, Charles Lanks, Harry B. Rossiter, Richard Casaburi and William W. Stringer

J. Clin. Med. 2024, 13(18), 5590; https://doi.org/10.3390/jcm13185590 - 20 Sep 2024

Cited by 2 | Viewed by 2049

Abstract

Objectives: Fatigue is a prominent feature of long COVID (LC) and may be related to several pathophysiologic mechanisms, including immune hyperstimulation. Aerobic endurance exercise training may be a useful therapy, with appropriate attention to preventing post-exertional malaise. Methods: Fourteen participants completed a pilot [...] Read more.

Objectives: Fatigue is a prominent feature of long COVID (LC) and may be related to several pathophysiologic mechanisms, including immune hyperstimulation. Aerobic endurance exercise training may be a useful therapy, with appropriate attention to preventing post-exertional malaise. Methods: Fourteen participants completed a pilot study of aerobic exercise training (twenty 1.5 h sessions of over 10 weeks). Cardiorespiratory fitness, 6 min walk distance, quality of life, symptoms, 7-day physical activity, immunophenotype, and inflammatory biomarkers were measured before and after exercise training. Results: The participant characteristics at baseline were as follows: 53.5 ± 11.6 yrs, 53% f, BMI 32.5 ± 8.4, 42% ex-smokers, 15.1 ± 8.8 months since initial COVID-19 infection, low normal pulmonary function testing,

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O_2peak 19.3 ± 5.1 mL/kg/min, 87 ± 17% predicted. After exercise training, participants significantly increased their peak work rate (+16 ± 20 W, p = 0.010) and

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O_2peak (+1.55 ± 2.4 mL/kg/min, p = 0.030). Patients reported improvements in fatigue severity (−11%), depression (−42%), anxiety (−29%), and dyspnea level (−46%). There were no changes in 6MW distance or physical activity. The circulating number of CD3+, CD4+, CD19+, CD14++CD16, and CD16++CD14+ monocytes and CD56+ cells (assessed with flow cytometry) increased with acute exercise (rest to peak) and was not diminished or augmented by exercise training. Plasma concentrations of TNF-α, IL-6, IL-8, IL-10, INF-γ, and INF-λ were normal at study entry and not affected by training. Conclusions: Aerobic endurance exercise training in individuals with LC delivered beneficial effects on cardiorespiratory fitness, quality of life, anxiety, depression, and fatigue without detrimental effects on immunologic function. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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19 pages, 1561 KiB

Open AccessArticle

Effect of Physical Activity Behaviors, Team Sports, and Sitting Time on Body Image and Exercise Dependence

by Emanuel Festino, Olga Papale, Francesca Di Rocco, Marianna De Maio, Cristina Cortis and Andrea Fusco

Sports 2024, 12(9), 260; https://doi.org/10.3390/sports12090260 - 20 Sep 2024

Cited by 2 | Viewed by 4183

Abstract

This study aimed to evaluate whether the type and degree of physical activity commitment (i.e., team sport athletes, highly active individuals, sedentary behavior) influence body image and exercise behavior. A total of 96 participants (46 women and 50 men; age: 22.7 ± 2.7 [...] Read more.

This study aimed to evaluate whether the type and degree of physical activity commitment (i.e., team sport athletes, highly active individuals, sedentary behavior) influence body image and exercise behavior. A total of 96 participants (46 women and 50 men; age: 22.7 ± 2.7 years; height: 170 ± 8.6 cm; weight: 67.6 ± 10.8 kg) were divided in six groups: female volleyball and male football players (student athletes classified as Tier 2), highly physically active women and men, with high sitting time completed the Body Image Dimensional Assessment and the 21-item Exercise Dependence Scale to evaluate body dissatisfaction and level of dependency on exercise. The Body Image Dimensional Assessment is a silhouette-based scale, where three direct indices are derived from the participants’ responses: body dissatisfaction, sexual body dissatisfaction, and comparative body dissatisfaction. The Exercise Dependence Scale is a six-point Likert scale that evaluates seven dimensions of exercise dependence (tolerance, withdrawal, intention effects, lack of control, time, reductions in other activities, and continuance) and provides an overall score. A multivariate analysis of variance was used to examine the effects of different levels of physical activity, team sport participation (volleyball and football), and sedentary behavior (i.e., high sitting time) on participants’ body image indices and dimensions of exercise dependence according to sex. Volleyball players showed significantly higher body dissatisfaction than football players (d = 0.99) and the physically active men group (d = 2.31), who had lower values than sedentary women group (d = 1.68). Football players had lower comparative body dissatisfaction values than volleyball players (d = 1.70) and sedentary women (d = 1.69), who had higher values than sedentary men (d = 1.04). Sedentary women had a significantly lower exercise dependence scale score than volleyball players (d = 1.71), football players (d = 1.12), and physically active men (d = 1.21). The findings highlight the impact of regular physical activity on body dissatisfaction and the variance in body image perceptions between the sexes. Moreover, the high exercise dependence values found in volleyball and football players and physically active men suggest an effect of intense training and maladaptive exercise behaviors, underlining the need for comprehensive strategies to address exercise dependence. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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13 pages, 1595 KiB

Open AccessArticle

Preconception Physical Exercise Is Associated with Phenotype-Specific Cardiovascular Alterations in Women at Risk for Gestational Hypertensive Disorders

by Pauline Dreesen, Pauline Volders, Dorien Lanssens, Sandy Nouwen, Birgit Vrancken, Febe Janssen, Bert O. Eijnde, Dominique Hansen, Michael Ceulemans, Adelheid Soubry and Wilfried Gyselaers

J. Clin. Med. 2024, 13(14), 4164; https://doi.org/10.3390/jcm13144164 - 16 Jul 2024

Cited by 2 | Viewed by 1462

Abstract

Background/Objectives: Gestational hypertensive disorders (GHD) pose significant maternal and fetal health risks during pregnancy. Preconception physical exercise has been associated with a lower incidence of GHD, but insights into the cardiovascular mechanisms remain limited. This study aimed to evaluate the effect of [...] Read more.

Background/Objectives: Gestational hypertensive disorders (GHD) pose significant maternal and fetal health risks during pregnancy. Preconception physical exercise has been associated with a lower incidence of GHD, but insights into the cardiovascular mechanisms remain limited. This study aimed to evaluate the effect of preconception physical exercise on the complete cardiovascular functions of women at risk for GHD in a subsequent pregnancy. Methods: A non-invasive hemodynamics assessment of arteries, veins, and the heart was performed on 40 non-pregnant women at risk for developing GHD in a subsequent pregnancy. Measurements of an electrocardiogram Doppler ultrasound, impedance cardiography and bio-impedance spectrum analysis were taken before and after they engaged in physical exercise (30–50 min, 3×/week, 4–6 months). Results: After a mean physical exercise period of 29.80 weeks, the total peripheral resistance (TPR), diastolic blood pressure and mean arterial pressure decreased in the total study population, without changing cardiac output (CO). However, in 42% (9/21) of women categorized with high or low baseline CO (>P75 or <P25 resp.), a shift in CO was observed towards the normal reference interquartile range (P25–P75). This was associated with improved hepatic venous and central arterial hemodynamic functions. Similar changes in TPR occurred in 38% (11/29) of women classified as having low or high baseline TPR. Conclusions: As in pregnancy, output- or resistance-dominant cardiovascular profiles already exist prior to conception. This study illustrates that preconception physical exercise shifts high or low CO and/or TPR towards the normal midrange, allowing women at risk for GHD to start a subsequent pregnancy with a more gestation-adaptable cardiovascular system. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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13 pages, 1369 KiB

Open AccessArticle

Assessing the Risk of Normal Weight Obesity in Korean Women across Generations: A Study on Body Composition and Physical Fitness

by Yeong-Hyun Cho, Hyuk Sakong, Myung-Jin Oh and Tae-Beom Seo

Healthcare 2024, 12(11), 1142; https://doi.org/10.3390/healthcare12111142 - 4 Jun 2024

Cited by 1 | Viewed by 1450

Abstract

Normal weight obesity (NWO) refers to a condition in which the body mass index falls within the normal range, but the percent of body fat is excessive. Although there are reports of a high prevalence of cardiovascular and metabolic diseases in NWO, analyses [...] Read more.

Normal weight obesity (NWO) refers to a condition in which the body mass index falls within the normal range, but the percent of body fat is excessive. Although there are reports of a high prevalence of cardiovascular and metabolic diseases in NWO, analyses regarding physical fitness have been lacking. Therefore, the purpose of this study was to analyze the age-related prevalence of NWO and to examine physical fitness across generations. Our study utilized a dataset comprising 119,835 participants for analysis. The prevalence of NWO across ages was examined using cross-tabulation analysis. For body composition and physical fitness, medians and group differences were assessed by generation through Kruskal–Wallis and Bonferroni post hoc tests. Additionally, univariate logistic regression was adopted to analyze the odds ratio. The prevalence of NWO in Korean women was 18.3%. The fat-free mass of the NWO group was consistently lower than that of both the group with normal body mass indexes (Normal) and obese body mass indexes (Obesity) across all generations. Additionally, the waist circumference and blood pressure were greater in the now group than in the Normal group. When considering maximal strength, muscle endurance, power, balance, and coordination, the NWO group exhibited lower levels compared to the Normal group. The NWO group showed lower muscle mass than both the Normal and Obesity groups, resulting in significantly reduced physical fitness compared to that of the Normal group, similar to the Obesity group. This condition may increase not only the risk of posing a potentially more serious health concern than obesity but also the risk of falls in elderly people. Therefore, based on this study, it is crucial to not only define obesity using BMI criteria but also to diagnose NWO. Public health policies and preventive measures must be implemented accordingly. Full article

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11 pages, 604 KiB

Open AccessArticle

FTO rs9939609: T>A Variant and Physical Inactivity as Important Risk Factors for Class III Obesity: A Cross-Sectional Study

by Erika Martínez-López, Mariana Perez-Robles, Joel Torres-Vanegas, Sissi Godinez-Mora, Iris Monserrat Llamas-Covarrubias and Wendy Campos-Perez

Healthcare 2024, 12(7), 787; https://doi.org/10.3390/healthcare12070787 - 4 Apr 2024

Cited by 2 | Viewed by 2454

Abstract

Background: The prevalence of obesity has been increasing worldwide. It has been reported that physiological and environmental factors such as diet, culture, physical activity, and genetics are the principal factors related to obesity. The fat mass and obesity-associated (FTO) gen variant [...] Read more.

Background: The prevalence of obesity has been increasing worldwide. It has been reported that physiological and environmental factors such as diet, culture, physical activity, and genetics are the principal factors related to obesity. The fat mass and obesity-associated (FTO) gen variant (rs9939609: T>A) has been associated with class III obesity. The A variant has been correlated with anthropometric and metabolic alterations. Therefore, the purpose of this study was to analyze the association of the FTO rs9939609: T>A variant and environmental factors with clinical, anthropometric, and biochemical variables in subjects with class III obesity. Results: The A variant frequency was higher in the class III obesity group compared with the normal weight group (44% vs. 25%, p < 0.001). Subjects with the AA genotype had a higher body mass index (BMI) than those with the AT genotype (35.46 kg/m² (31–39.8) vs. 26.91 kg/m² (23.7–30), p = 0.005). Women with the AA genotype showed higher waist circumferences than the AT group (101.07 cm (90.9–111.1) vs. 85.45 cm (77–93.8) p = 0.047). The FTO A variant increases the risk by 3.54 times and physical inactivity increases the risk by 6.37 times for class III obesity. Conclusions: Our results suggest that among the studied variables, those most related to class III obesity were the FTO risk genotype (A allele) and physical inactivity. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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13 pages, 300 KiB

Open AccessArticle

The Impact of Competitive Sports on Oral Health: Exploring Their Relationship with Salivary Oxidative Stress in Children

by Mădălina Nicoleta Matei, Paul Șerban Popa, Antonela Magdalena Covaci, Oana Chipirliu, Kamel Earar, George Stoica, Andreea Eliza Zaharia, Nicoleta Maricica Maftei, Gabriela Gurău, Elena Lăcrămioara Lisă and Anamaria Zaharescu

Healthcare 2023, 11(22), 2927; https://doi.org/10.3390/healthcare11222927 - 8 Nov 2023

Cited by 1 | Viewed by 1849

Abstract

This article explores the correlation between salivary biomarkers, such as glutathione peroxidase (GPX), total antioxidant capacity (TAC), and superoxide dismutase (SOD), and their association with oral health for children in competitive sports. Saliva has emerged as a valuable resource for evaluating physiological and [...] Read more.

This article explores the correlation between salivary biomarkers, such as glutathione peroxidase (GPX), total antioxidant capacity (TAC), and superoxide dismutase (SOD), and their association with oral health for children in competitive sports. Saliva has emerged as a valuable resource for evaluating physiological and pathological conditions due to its non-invasive collection method and easy storage. This study examines the potential of GPX, TAC, and SOD as salivary biomarkers for assessing the impact of competitive sports on children’s oral health. It discusses the potential implications of increased oxidative stress due to intense physical activity and the role of antioxidant defense mechanisms in maintaining oral health. In total, 173 children aged between 6 and 17 were divided into three groups, 58 hockey players, 55 football players, and 60 in the control group, and examined to assess their oral hygiene and dental and periodontal health. Saliva was collected, centrifuged, and the supernatant was analyzed for the relevant biomarkers. The findings seem to suggest that salivary biomarkers, like GPX, TAC, and SOD, might serve as indicators of the physiological response to competitive sports in children, as well as indicators of oral health, especially dental cavities, and periodontal disease. Statistical analysis showed significant differences between the groups, with better values for athletes, regardless of age, sex, or activity type. Understanding the relationship between salivary biomarkers and competitive sports in children can have significant implications for monitoring and optimizing the health and performance of young athletes. Further research is needed to establish the specific associations between these biomarkers and the effects of several types and intensities of sports activities on oral health in children. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

10 pages, 869 KiB

Open AccessArticle

Exploring an Unknown Corner of a Well-Known Topic: HIIE Influence on Renal Health and Filtration in Healthy Individuals Free of Cardiometabolic Diseases

by Jeffrey S. Forsse, Kathleen A. Richardson, Ricardo Torres, Catherine Lowry, James Kyle Taylor, Cassidy L. Beeson, Jacob Ward, Anurag Dhillon, Brock Niceler, Ahmed Ismaeel and Panagiotis Koutakis

Sports 2023, 11(11), 210; https://doi.org/10.3390/sports11110210 - 30 Oct 2023

Viewed by 2058

Abstract

Aerobic exercise, specifically high-intensity interval exercise (HIIE), and its effects on renal health and filtration (RHF) are not well understood. Several studies support incorporating contemporary biomarkers serum cystatin C (CyC) and urine epidermal growth factor (uEGF) to combat the volatility of serum creatinine [...] Read more.

Aerobic exercise, specifically high-intensity interval exercise (HIIE), and its effects on renal health and filtration (RHF) are not well understood. Several studies support incorporating contemporary biomarkers serum cystatin C (CyC) and urine epidermal growth factor (uEGF) to combat the volatility of serum creatinine (sCr). Using these biomarkers, we examined the acute influences HIIE has on RHF to determine if there is a ceiling effect in healthy populations. The purpose was to determine the influence of an acute bout of HIIE on RHF. Thirty-six participants (n = 22 males; n = 14 females; age 37.6 ± 12.4 years.; BF% 19.2 ± 7.1%; VO₂max 41.8 + 7.4 mL/kg/min) completed 30 min of HIIE on a treadmill (80% and 40% of VO₂reserve in 3:2 min ratio). Blood and urine samples were obtained under standardized conditions before, 1 h, and 24 h post-exercise. CyC, sCR, uEGF, urine creatinine (uCr), uCr/uEGF ratio, and multiple estimates of glomerular filtration rate (eGFR) Modification of Diet in Renal Disease (MDRD) and CKD-EPI equations were used. The analysis employed paired sample t-tests and repeated measures ANOVAs. CyC, uEGF, uCr, and uCr/uEGF ratio concentrations were not altered between timepoints. sCr increased 1 h post-exercise (p > 0.002) but not at 24 h post-exercise. eGFR decreased in the MDRD and CKD-EPI equations at 1 h (p > 0.012) with no changes at 24 h post-exercise. CyC and sCr/CyC demonstrated no significant changes. CyC and uEGF are not altered by acute HIIE. The results demonstrate a potential ceiling effect in contemporary and traditional biomarkers of RHF, indicating improvements in RHF may be isolated to populations with reduced kidney function. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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9 pages, 233 KiB

Open AccessArticle

The Impact of Exercise Training on Physical Activity among Elderly Women in the Community: A Pilot Study

by You-Ying Lii, Yao-Chung Tai, Hung-Yi Wang, I-Chen Yeh, Yen-Chun Chiu, Chieh-Yi Hou and Feng-Hua Tsai

Healthcare 2023, 11(18), 2601; https://doi.org/10.3390/healthcare11182601 - 21 Sep 2023

Cited by 2 | Viewed by 1757

Abstract

According to a survey conducted by the Taiwanese government, the elderly spend most of their time watching TV for their daily leisure activities, and most do not pant or sweat during exercise. Relevant studies have shown that physical activity has benefits and importance [...] Read more.

According to a survey conducted by the Taiwanese government, the elderly spend most of their time watching TV for their daily leisure activities, and most do not pant or sweat during exercise. Relevant studies have shown that physical activity has benefits and importance for the physical functions of the elderly. The objective of this study was to investigate the effects of exercise training on the functional fitness of elderly females in the community. The women subjects were from the community of Kaohsiung City, Taiwan. In total, 34 females were randomly divided into an intervention group and a control group. The ages of the subjects ranged from 65 to 80 years old, with an average age of 75.13. The experimental group continued their physical activity intervention for 20 weeks. The control group had no training plan. The results of the study showed that after 20 weeks of intervention, participants in the intervention group experienced improvements in back grasping, right-hand grip strength, sitting to standing, right hip flexion, right knee extension, right ankle dorsiflexion, right sitting forward extension balance, and sitting back around objects. Six-minute walking distances also showed a significant difference in all cases. The results demonstrated that the 20-week physical activity program intervention used in this study can assist in improving back grasping, right-hand grip strength, sitting to standing, right-hand sitting posture, forward balance, sitting back around objects, and six-minute walking distance among older women in the community. In summary, we recommend a moderate-intensity physical activity exercise program for older women in the community. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

10 pages, 280 KiB

Open AccessArticle

A Repeated Cross-Sectional Pilot Study of Physical Activity, Levels of Depression and Anxiety during the COVID-19 Pandemic in Young Greek Adults

by Smaragda Skalidou, Andreas Anestis, Emmanouil Skalidis, Ourania Kontaxi, Athanasia Kyrezi, Panagiota Konstantinou and Konstantinos Papadimitriou

Healthcare 2023, 11(18), 2493; https://doi.org/10.3390/healthcare11182493 - 8 Sep 2023

Cited by 2 | Viewed by 1547

Abstract

Regular physical activity (PA) and, more specifically, exercise, is associated with lower levels of stress, depression, and anxiety. The aim of this repeated cross-sectional pilot study was to investigate the impact of participating in PA on the mental health of young adults in [...] Read more.

Regular physical activity (PA) and, more specifically, exercise, is associated with lower levels of stress, depression, and anxiety. The aim of this repeated cross-sectional pilot study was to investigate the impact of participating in PA on the mental health of young adults in Greece during the COVID-19 pandemic. The study was carried out during two quarantine periods: Survey I on 5 May 2020, and Survey II on 30 April 2021. The Hamilton Anxiety (HAM-A) and Beck Depression Inventory-II (BDI-II) scales and the level of PA were used to assess a sample of individuals aged between 18 and 26 years old. In 2020 and 2021, a total of 268 (33.9% males) and 380 (37.1% females) subjects participated in the studies, respectively. According to the findings, the vast majority of the participants in both samples reported that they are physically active (p = 0.86), while they consider exercise as a significant health factor (p = 0.10). Moreover, anxiety levels statistically significant increased (p = 0.001), while depression levels remained relatively stable with a slight increase of approximately (p > 0.05). Additionally, in both surveys, individuals who engaged in a PA program exhibited reduced levels of depression and anxiety (p = 0.001). Also, gender appears to influence anxiety and depression levels, while a lack of exercise exacerbates these measures in both genders when compared to physically active individuals. Concludingly, it is crucial for public health strategies to include interventions that promote safe PA in the event of future lockdowns or similar emergencies. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

12 pages, 999 KiB

Open AccessArticle

Impact of Physical Fitness on Emergency Response: A Case Study of Factors That Influence Individual Responses to Emergencies among University Students

by Senka Bajić, Dragoljub Veljović and Borko Đ. Bulajić

Healthcare 2023, 11(14), 2061; https://doi.org/10.3390/healthcare11142061 - 19 Jul 2023

Cited by 1 | Viewed by 3293

Abstract

(1) Background: The purpose of this study was to ascertain whether there is a direct correlation between the physical fitness of the general population, specifically students, and the response times to fire-emergency-related building evacuations and to identify which physical fitness factors more significantly [...] Read more.

(1) Background: The purpose of this study was to ascertain whether there is a direct correlation between the physical fitness of the general population, specifically students, and the response times to fire-emergency-related building evacuations and to identify which physical fitness factors more significantly influenced emergency movement times. (2) Methods: In this quantitative investigation, 21 students (both men and women of the same age) volunteered to participate. We first evaluated their physical fitness; then, we analyzed their reaction times and speed. (3) Results: The results of this study revealed a relationship between emergency response times and evaluations of muscular strength, muscular endurance, muscle power, cardiorespiratory fitness, and body composition. The physically active group demonstrated a stronger initial response (i.e., a shorter time to reach a safe location) to fictitious emergency scenarios. The reduction in the necessary response time did not, however, appear to be related to the degree of flexibility. (4) Conclusions: This study showed how physical fitness might alter initial emergency response times and lessen the effects of a disaster on the general population. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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20 pages, 680 KiB

Open AccessReview

Exercise for Mental Well-Being: Exploring Neurobiological Advances and Intervention Effects in Depression

by Jianchang Ren and Haili Xiao

Life 2023, 13(7), 1505; https://doi.org/10.3390/life13071505 - 4 Jul 2023

Cited by 24 | Viewed by 15841 | Correction

Abstract

Depression is a common mental disorder in which patients often experience feelings of sadness, fatigue, loss of interest, and pleasure. Exercise is a widely used intervention for managing depression, but the specific molecular mechanisms underlying its antidepressant effect are unclear. In this narrative [...] Read more.

Depression is a common mental disorder in which patients often experience feelings of sadness, fatigue, loss of interest, and pleasure. Exercise is a widely used intervention for managing depression, but the specific molecular mechanisms underlying its antidepressant effect are unclear. In this narrative review, we aim to synthesize current knowledge on the molecular, neural, and physiological mechanisms through which exercise exerts its antidepressant effect and discuss the various exercise interventions used for managing depression. We conducted a narrative review of the literature on the topic of exercise and depression. Our review suggests that exercise impacts peripheral tryptophan metabolism, central inflammation, and brain-derived neurotrophic factors through the peroxisome proliferator-activated receptor γ activating factor 1α (PGC-1α) in skeletal muscles. The uncarboxylated osteocalcin facilitates “bone-brain crosstalk”, and exercise corrects atypical expression of brain-gut peptides, modulates cytokine production and neurotransmitter release, and regulates inflammatory pathways and microRNA expression. Aerobic exercise is recommended at frequencies of 3 to 5 times per week with medium to high intensity. Here we highlight the significant potential of exercise therapy in managing depression, supported by the molecular, neural, and physiological mechanisms underlying its antidepressant effect. Understanding the molecular pathways and neural mechanisms involved in exercise’s antidepressant effect opens new avenues for developing novel therapies for managing depression. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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12 pages, 640 KiB

Open AccessArticle

Optimal Physical Activity Is Associated with the Reduction of Depressive Symptoms via Neuroticism and Resilience

by Kazuki Nakajima, Akiyoshi Shimura, Masayuki Kikkawa, Shunichiro Ito, Mina Honyashiki, Yu Tamada, Shinji Higashi, Masahiko Ichiki, Takeshi Inoue and Jiro Masuya

Healthcare 2023, 11(13), 1900; https://doi.org/10.3390/healthcare11131900 - 30 Jun 2023

Cited by 4 | Viewed by 2078

Abstract

Background: Personality traits, such as neuroticism, that results in vulnerability to stress, and resilience, a measure of stress coping, are closely associated with the onset of depressive symptoms, whereas regular physical activity habits have been shown to reduce depressive symptoms. In this study, [...] Read more.

Background: Personality traits, such as neuroticism, that results in vulnerability to stress, and resilience, a measure of stress coping, are closely associated with the onset of depressive symptoms, whereas regular physical activity habits have been shown to reduce depressive symptoms. In this study, the mediating effects of neuroticism and resilience between physical activity duration and depressive symptoms were investigated by a covariance structure analysis. Methods: Between April 2017 and April 2018, 526 adult volunteers were surveyed using self-administered questionnaires. Demographic information, habitual physical activity duration (PAD), neuroticism, and resilience were investigated. The effects of these factors on depressive symptoms were analyzed by a covariance structure analysis. This study was conducted with the approval of the Medical Ethics Committee of Tokyo Medical University. Results: The dose–response curves of physical activity duration and depression scores were U-shaped: the optimal physical activity duration for the lowest depression score was 25.7 h/week. We found that the greater the difference from the optimal PAD, the higher the neuroticism and the lower the resilience, and the more severe the depressive symptoms. Covariance structure analysis demonstrated that neuroticism and resilience significantly and completely mediated the effects of the difference from the optimal PAD on depressive symptoms (coefficient of determination R² = 0.349). Conclusion: Our study suggests that there is an optimal PAD that reduces depressive symptoms, and that a greater difference from the optimal PAD increases depressive symptoms through neuroticism and resilience. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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18 pages, 566 KiB

Open AccessArticle

Effects of a Home-Based Physical Activity Program on Blood Biomarkers and Health-Related Quality of Life Indices in Saudi Arabian Type 2 Diabetes Mellitus Patients: A Randomized Controlled Trial

by Jonathan Sinclair, Hussein Ageely, Mohamed Salih Mahfouz, Abdulrahman Ahmed Hummadi, Hussain Darraj, Yahia Solan, Robert Allan, Fatma Bahsan, Hassan AL Hafaf, Ali Abohadash, Mohammed Badedi and Lindsay Bottoms

Life 2023, 13(6), 1413; https://doi.org/10.3390/life13061413 - 19 Jun 2023

Cited by 2 | Viewed by 2763

Abstract

The purpose of this study was to undertake a randomized control trial examining the effects of a 12-week home-based physical activity program on Saudi Arabian adults with type 2 diabetes. Sixty-four patients with type 2 diabetes mellitus were recruited from the Jazan Diabetes [...] Read more.

The purpose of this study was to undertake a randomized control trial examining the effects of a 12-week home-based physical activity program on Saudi Arabian adults with type 2 diabetes. Sixty-four patients with type 2 diabetes mellitus were recruited from the Jazan Diabetes and Endocrinology Center, located in the Jazan region of southwestern Saudi Arabia. Patients were randomly assigned to either control, i.e., usual care (males = 46.9% and females = 53.1%, age = 45.88 ± 8.51 years, mass = 76.30 ± 15.16 kg, stature = 160.59 ± 8.94 cm, body mass index (BMI) = 29.73 ± 6.24 kg/m², years since diagnosis = 8.12 ± 6.22 years) or a home-based physical activity (males = 50% and females = 50%, age = 42.07 ± 9.72 years, mass = 74.58 ± 13.67 kg, stature = 158.94 ± 9.38 cm, BMI = 29.44 ± 4.38 kg/m², years since diagnosis = 12.17 ± 8.38 years) trial arms. The home-based physical activity group was required to undertake aerobic training by increasing their habitual step count by 2000 steps per day and performing resistance training 3 times per week for 12 weeks. The primary outcome was hemoglobin A1c (HbA1c), and secondary measures of anthropometrics, blood biomarkers, physical fitness, and patient-reported quality of life outcomes pertinent to type 2 diabetes were measured at timepoints, i.e., baseline, 12 weeks, and 24 weeks (follow-up). Intention-to-treat analyses revealed no significant alterations in the primary outcome (control: baseline = 8.71%, 12-weeks = 8.35%, and follow-up = 8.72%; home-based physical activity: baseline = 8.32%, 12-weeks = 8.06%, and follow-up = 8.39%) between trial arms. However, improvements in psychological wellbeing at follow-up measured using the Patient Health Questionnaire-9 were significantly greater in the home-based physical activity group (baseline = 6.84, 12-weeks = 5.96, and follow-up = 5.00) compared to the control (baseline = 6.81, 12-weeks = 5.73, and follow-up = 8.53). No other statistically significant observations were observed. Home-based physical activity is not effective in mediating improvements in HbA1c levels or secondary hematological, blood pressure, anthropometric, or fitness indices. However, given the link between psychological wellbeing and the etiology/progression of disease activity in type 2 diabetes, home-based physical activity may be effective for tertiary disease management. Future trials should examine the efficacy of relative exercise intensities greater than those in the current study. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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14 pages, 1952 KiB

Open AccessReview

Effects of Tai Chi on Postural Control in People with Peripheral Neuropathy: A Systematic Review with Meta-Analysis

by Wenhui Mao, Ting Wang, Mengzi Sun, Fangtong Zhang and Li Li

Healthcare 2023, 11(11), 1559; https://doi.org/10.3390/healthcare11111559 - 26 May 2023

Cited by 5 | Viewed by 2193

Abstract

Background: Effects of Tai Chi on people with peripheral neuropathy (PN) are not yet apparent. This systematic review was conducted to evaluate the effects of Tai Chi on postural control in people with PN. Methods: Literature was screened in seven databases for relevant [...] Read more.

Background: Effects of Tai Chi on people with peripheral neuropathy (PN) are not yet apparent. This systematic review was conducted to evaluate the effects of Tai Chi on postural control in people with PN. Methods: Literature was screened in seven databases for relevant randomized controlled trials. The reports and methodological quality were evaluated. A meta-analysis was performed using RevMan5.4 software. Results: Ten reports were included, involving a total of 344 subjects. The meta-analysis found that Tai Chi therapy for people with PN resulted in a smaller sway area, in the double-leg stance with eyes closed test (SMD = −2.43, I² = 0%), than that observed in the control group, greater distance covered in the six-minute walking test (SMD = −0.46, I² = 49%) and faster performance in the timed-up-and-go test (SMD = 0.68, I² = 50%), than the baseline. Conclusions: Tai chi effectively enhanced dynamic postural control in people with PN. However, no better effects on postural control from Tai Chi than from other rehabilitation approaches were observed in this study. Further high-quality trials are needed to better understand Tai Chi’s effects on individuals with PN. Full article

(This article belongs to the Topic Physical Exercise Impacts on Human Physical and Psychological Health)

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