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Diagnostics, Volume 15, Issue 4

February-2 2025 - 113 articles

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Cover Story: Metabolic changes during pregnancy affect the blood components critical for diagnosing various pregnancy-related or non-pregnancy-related diseases. Reference values for laboratory parameters in pregnancy differ from those for non-pregnant women, but results are often reported using non-pregnant reference values, potentially leading to misinterpretation, additional diagnostics and unnecessary stress for pregnant women. The primary challenge in establishing reference intervals in pregnancy is the continuous metabolic changes. In addition, reference intervals should be evaluated in terms of their clinical significance for distinguishing physiologic from disease-related changes. The aim of this study is to establish reference values for common laboratory parameters in early pregnancy and to evaluate their clinically significant differences compared to non-pregnant reference intervals. View this paper

Articles (113)

  • Article
  • Open Access
1 Citations
4,951 Views
12 Pages

Deep Learning-Based Periapical Lesion Detection on Panoramic Radiographs

  • Viktor Szabó,
  • Kaan Orhan,
  • Csaba Dobó-Nagy,
  • Dániel Sándor Veres,
  • David Manulis,
  • Matvey Ezhov,
  • Alex Sanders and
  • Bence Tamás Szabó

19 February 2025

Background/Objectives: Our study aimed to determine the accuracy of the artificial intelligence-based Diagnocat system (DC) in detecting periapical lesions (PL) on panoramic radiographs (PRs). Methods: 616 teeth were selected from 357 panoramic radio...

  • Article
  • Open Access
971 Views
12 Pages

Exploring Cardiac Sympathetic Denervation in Transthyretin-Mediated Hereditary Amyloidosis (ATTRv): Insights from 123I-mIBG Scintigraphy

  • Maria Silvia De Feo,
  • Chiara Cambieri,
  • Eleonora Galosi,
  • Viviana Frantellizzi,
  • Cristina Chimenti,
  • Marco Luigetti,
  • Maria Ausilia Sciarrone,
  • Francesca Graziani,
  • Luca Leonardi and
  • Beatrice Musumeci
  • + 10 authors

19 February 2025

Background/Objectives: Hereditary transthyretin-mediated amyloidosis (ATTRv) is a rare disease characterized by the deposition of amyloid in the heart and peripheral nerves, particularly affecting small fibers. This study aims to evaluate autonomic c...

  • Review
  • Open Access
1 Citations
2,314 Views
16 Pages

19 February 2025

Interstitial lung abnormalities (ILAs) are incidental radiologic abnormalities on chest computed tomography (CT) examination performed on people in whom interstitial lung disease (ILD) is not suspected. Despite the fact that most of these individuals...

  • Article
  • Open Access
1 Citations
803 Views
11 Pages

Association Between Mandibular Cortical Erosion and Bone Mineral Density Assessed by Phalangeal Ultrasound and Dual Energy X-Ray Absorptiometry in Spanish Women

  • Maria L. Canal-Macías,
  • Vicente Vera-Rodríguez,
  • Olga Leal-Hernández,
  • Julián Fernando Calderón-García,
  • Raúl Roncero-Martín,
  • Francisco García-Blázquez,
  • Sergio Rico-Martín,
  • Fidel López-Espuela,
  • José M. Morán and
  • Juan Fabregat-Fernández
  • + 2 authors

19 February 2025

Background and Objectives: Analysing the characteristics of the mandibular bone through panoramic radiographs could be useful as a prescreening tool for detecting individuals with osteoporosis. The aims of this study were to evaluate the possible ass...

  • Article
  • Open Access
1 Citations
1,832 Views
17 Pages

19 February 2025

Background/Objectives: Vascular malformations form masses in subcutaneous and muscular tissues throughout the body and are occasionally misdiagnosed as subcutaneous nonvascular tumors. Understanding and differentiating their clinical and imaging feat...

  • Article
  • Open Access
1 Citations
1,610 Views
12 Pages

Epidemiology of Celiac Disease in Cantabria, Spain

  • Alejandra Blanco-García,
  • Marcos López-Hoyos,
  • Juan Irure-Ventura and
  • Pedro Muñoz-Cacho

19 February 2025

Background/Objectives: Celiac disease is an enteropathy caused by a systemic autoimmune process of genetic predisposition to the ingestion of gluten. It is a public health problem worldwide because there are often long delays between the onset of sym...

  • Article
  • Open Access
2 Citations
1,022 Views
19 Pages

19 February 2025

Background/Objectives: While gradient-echo (GRE)-based chemical shift-encoded magnetic resonance imaging (CSE-MRI) offers precise method for measuring adiposity in bone marrow, its limitation lies in the need for additional imaging. On the other hand...

  • Review
  • Open Access
2 Citations
2,842 Views
15 Pages

Trends in Clinical Cardiac Photon-Counting Detector CT Research: A Comprehensive Bibliometric Analysis

  • Arosh S. Perera Molligoda Arachchige,
  • Federica Catapano,
  • Costanza Lisi,
  • Jad El Choueiri,
  • Francesca Pellicanò,
  • Stefano Figliozzi,
  • Letterio S. Politi and
  • Marco Francone

19 February 2025

Photon-counting detector computed tomography (PCD-CT) represents a significant advancement in radiological imaging, offering substantial potential for cardiac applications that remain partially underexplored. This bibliometric analysis investigates t...

  • Article
  • Open Access
1,121 Views
10 Pages

Comparative Clinical and Histopathological Study of Oral Leukoplakia in Smokers and Non-Smokers

  • Andrei-Eduard Șerban,
  • Ioanina Părlătescu,
  • Elena Milanesi,
  • Iulia Andreea Pelisenco,
  • Maria Dobre,
  • Mariana Costache,
  • Șerban Țovaru and
  • Paula Perlea

19 February 2025

Background/Objectives: Oral leukoplakia (OLK) is an oral mucosal lesion classified in the oral potentially malignant disorder group and is associated with an increased risk of malignant transformation (MT). The aim of this study was to compare the cl...

  • Article
  • Open Access
3 Citations
1,498 Views
34 Pages

19 February 2025

Background: Surgical site infections (SSIs) lead to higher hospital readmission rates and healthcare costs, representing a significant global healthcare burden. Machine learning (ML) has demonstrated potential in predicting SSIs; however, the challen...

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