Diagnostics, Volume 15, Issue 4
February-2 2025 - 113 articles
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Cover Story: Metabolic changes during pregnancy affect the blood components critical for diagnosing various pregnancy-related or non-pregnancy-related diseases. Reference values for laboratory parameters in pregnancy differ from those for non-pregnant women, but results are often reported using non-pregnant reference values, potentially leading to misinterpretation, additional diagnostics and unnecessary stress for pregnant women. The primary challenge in establishing reference intervals in pregnancy is the continuous metabolic changes. In addition, reference intervals should be evaluated in terms of their clinical significance for distinguishing physiologic from disease-related changes. The aim of this study is to establish reference values for common laboratory parameters in early pregnancy and to evaluate their clinically significant differences compared to non-pregnant reference intervals. View this paper