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Most Cited

  • Review
  • Open Access
14 Citations
6,990 Views
10 Pages

30 May 2023

Machine learning is being increasingly applied in various aspects of medicine. The availability of large amounts of digital health records has enabled researchers to apply machine learning algorithms to tackle different medical problems. Urinary trac...

  • Review
  • Open Access
13 Citations
6,539 Views
11 Pages

Relationships between Oral Health and the Sustainable Development Goals: A Scoping Review

  • Olunike Rebecca Abodunrin,
  • Mobolaji Timothy Olagunju,
  • Omolola Titilayo Alade and
  • Morẹ́nikẹ́ Oluwátóyìn Foláyan

30 October 2023

The aim of this scoping review was to map the research that links oral health and sustainable development goals (SDGs). The question that guided this review was what is the published evidence specifically linking oral health and SDGs? The search of a...

  • Opinion
  • Open Access
13 Citations
10,986 Views
16 Pages

30 May 2023

The COVID crisis of the past three years has greatly impacted stakeholder relationships between scientists, health providers, policy makers, pharmaceutical industry employees, and the public. Lockdowns and restrictions of civil liberties strained an...

  • Systematic Review
  • Open Access
12 Citations
8,688 Views
20 Pages

A Scoping Review on Coping Strategies and Quality of Life of Stroke Caregivers: Often Underestimated Variables in Stroke Recovery Process?

  • Anna Tsiakiri,
  • Pinelopi Vlotinou,
  • Aikaterini Paschalidou,
  • Christos Konstantinidis,
  • Foteini Christidi,
  • Dimitrios Tsiptsios,
  • Georgia Detsaridou,
  • Alexandra Petridou,
  • Aimilios Gkantzios and
  • Nikolaos Aggelousis
  • + 5 authors

18 July 2023

The purpose of the present study was to review all available work published within the last decade focusing on coping strategies in stroke caregivers and their impact on quality of Life (QoL) and psycho-emotional status. A literature search of two da...

  • Opinion
  • Open Access
12 Citations
7,939 Views
9 Pages

Untreated Early Childhood Caries and Possible Links with Brain Development

  • Morẹ́nikẹ́ Oluwátóyìn Foláyan,
  • Omowumi Moromoke Femi-Akinlosotu,
  • Bolu Adeoti and
  • Oluwatosin Eunice Olorunmoteni

28 September 2023

Untreated early childhood caries (ECC) is a global public health concern. In the short term, untreated ECC can lead to pain, infection, and disrupted sleep, among other issues. In the long term, it is associated with poor oral health in later life, i...

  • Communication
  • Open Access
10 Citations
5,582 Views
7 Pages

14 March 2023

The SARS-CoV2 pandemic is the most significant global health emergency of the last century. While the pathophysiology of SARS-CoV2 is understood, the early and long-term outcomes of natural infection are increasingly being recognised. Multisystem inf...

  • Article
  • Open Access
10 Citations
3,254 Views
25 Pages

Advancing Brain MRI Image Classification: Integrating VGG16 and ResNet50 with a Multi-Verse Optimization Method

  • Nazanin Tataei Sarshar,
  • Soroush Sadeghi,
  • Mohammadreza Kamsari,
  • Mahrokh Avazpour,
  • Saeid Jafarzadeh Ghoushchi and
  • Ramin Ranjbarzadeh

24 November 2024

Background/Objectives: The accurate categorization of brain MRI images into tumor and non-tumor categories is essential for a prompt and effective diagnosis. This paper presents a novel methodology utilizing advanced Convolutional Neural Network (CNN...

  • Article
  • Open Access
9 Citations
5,164 Views
16 Pages

Phytochemical Composition, In Silico Molecular Docking Analysis and Antibacterial Activity of Lawsonia inermis Linn Leaves Extracts against Extended Spectrum Beta-Lactamases-Producing Strains of Klebsiella pneumoniae

  • Adam Mustapha,
  • Ahmed Nouri AlSharksi,
  • Ukpai A. Eze,
  • Rahma Kudla Samaila,
  • Boniface Nwofoke Ukwah,
  • Arinze Favour Anyiam,
  • Shivanthi Samarasinghe and
  • Musa Adamu Ibrahim

26 August 2024

Klebsiella pneumoniae is an opportunistic Gram-negative bacterium in the Enterobacteriaceae family associated with a wide range of diseases, such as pneumonia, bloodstream infections, meningitis and urinary tract infections. Infections caused by drug...

  • Review
  • Open Access
9 Citations
4,611 Views
17 Pages

25 July 2024

Amid the global health crisis instigated by COVID-19, the resurgence of tuberculosis (TB) has underscored the urgent need for innovative solutions. With TB claiming 1.6 million lives in 2021, it remains a formidable challenge, particularly in underde...

  • Review
  • Open Access
8 Citations
13,585 Views
14 Pages

14 May 2024

The purpose of this review is to elucidate the different laboratory and biomarker testing methods available for screening and diagnosis of preeclampsia. These include routine testing, such as blood pressure readings, qualitative and quantitative urin...

  • Review
  • Open Access
7 Citations
4,568 Views
18 Pages

Oral Diseases and Adverse Pregnancy Outcomes in Sub-Saharan Africa: A Scoping Review

  • Ezekiel Taiwo Adebayo,
  • Olunike Rebecca Abodunrin,
  • Ifeoluwa E. Adewole,
  • Abideen Olurotimi Salako,
  • Joanne Lusher,
  • Folahanmi Tomiwa Akinsolu,
  • Maha El Tantawi,
  • Omolola Titilayo Alade,
  • George Uchenna Eleje and
  • Moréniké Oluwátóyìn Foláyan
  • + 1 author

29 December 2023

This scoping review mapped and critically reviewed the extant literature exploring associations between oral disease status and adverse pregnancy outcomes among women residing in sub-Saharan Africa. A literature search was conducted in July 2023 usin...

  • Review
  • Open Access
7 Citations
12,516 Views
18 Pages

10 March 2023

Recently, in Italy, a flowchart to be used by General Practitioners for the at-home treatment of patients with COVID-19, has been released. It states that early at-home treatment for SARS-CoV-2 infection is possible due to the availability of specifi...

  • Article
  • Open Access
7 Citations
7,358 Views
9 Pages

21 November 2023

Mandibular third molars are the most commonly impacted teeth. The prevalence and pattern of impacted mandibular third molars in patients presenting to the Obafemi Awolowo University Teaching Hospitals Complex, a tertiary hospital in south-western Nig...

  • Review
  • Open Access
6 Citations
6,474 Views
20 Pages

5 September 2024

Overuse or misuse of broad-spectrum antibiotics increases the risk of the emergence of antibiotic-resistant bacteria, which increases the possibility of antimicrobial-resistant (AMR) bacterial infections, and subsequently raises healthcare costs. The...

  • Article
  • Open Access
6 Citations
7,563 Views
11 Pages

HHV-6 in Cerebrospinal Fluid in Immunocompetent Children

  • Mikhail A. Nikolskiy,
  • Dmitriy A. Lioznov,
  • Evgeniy U. Gorelik and
  • Tatyana V. Vishnevskaya

20 September 2023

Background: Human herpes virus-6 (HHV-6) is a ubiquitous virus known as an etiological agent of exanthem subitum. HHV-6-encephalitis in immunocompetent children is a rare complication of the primary infection. There are a lack of data on the prevalen...

  • Review
  • Open Access
5 Citations
6,426 Views
29 Pages

Synthesis and Characterization of Carbonaceous Materials for Medical Applications: A Comprehensive Review

  • Ebenezer C. Nnadozie,
  • Kennedy I. Ogunwa,
  • Vitalis I. Chukwuike,
  • Onyinyechukwu O. Nnadozie and
  • Charles Ehikhase

2 November 2024

Carbonaceous materials have gained significant attention in recent years for their various applications in the field of medicine and biotechnology. This comprehensive review explores the synthesis and characterization of carbon-based materials and th...

  • Review
  • Open Access
4 Citations
4,213 Views
10 Pages

Assistive Communication Devices in Rett Syndrome: A Case Report and Narrative Review

  • Justin Lee,
  • Jessica Lee,
  • Mouath Abu-Daoud and
  • Yazan A. Al-Ajlouni

27 May 2024

Rett syndrome (RTT) is a severe neurodevelopmental disorder primarily affecting females, characterized by developmental regression and significant communication impairments. Despite the critical role of communication in maintaining quality of life, t...

  • Article
  • Open Access
4 Citations
4,698 Views
10 Pages

26 June 2024

Background: Pilates is among the best conservative management strategies for chronic low back pain. However, several variations of Pilates exist. This study aimed to investigate physical measures that would detect immediate changes after a brief sess...

  • Review
  • Open Access
4 Citations
3,612 Views
27 Pages

6 June 2023

The rapid spread of the new coronavirus disease (COVID-19) caused by SARS-CoV-2 has become a global pandemic. Although specific vaccines are available and natural drugs are being researched, supportive care and specific treatments to alleviate sympto...

  • Review
  • Open Access
3 Citations
3,679 Views
23 Pages

Application of the Hub-and-Spoke Model in Antimicrobial Stewardship Programmes: A Scoping Review

  • Ayesha Iqbal,
  • Yuhashinee Kumaradev,
  • Gizem Gülpinar,
  • Claire Brandish,
  • Maxencia Nabiryo,
  • Frances Garraghan,
  • Helena Rosado and
  • Victoria Rutter

1 October 2024

Background: The hub-and-spoke model (HSM) offers a framework for efficient healthcare service delivery. This scoping review seeks to explore the implementation and effectiveness of the HSM in antimicrobial stewardship (AMS) programmes. Methods: The P...

  • Article
  • Open Access
3 Citations
3,684 Views
18 Pages

Changing Responses during the COVID-19 Pandemic: A Comparison of Psychological Wellbeing and Work-Related Quality of Life of UK Health and Social Care Workers

  • Ruth D. Neill,
  • Paula McFadden,
  • Jill Manthorpe,
  • John Mallett,
  • Denise Currie,
  • Heike Schroder,
  • Jermaine Ravalier,
  • Patricia Nicholl,
  • John Moriarty and
  • Justin MacLochlainn
  • + 3 authors

26 July 2023

Aim: to explore the psychological wellbeing and work-related quality of life amongst United Kingdom (UK) health and social care workers during the COVID-19 pandemic. Subject and methods: Health and social care professionals within nursing, midwifery,...

  • Review
  • Open Access
3 Citations
9,892 Views
40 Pages

Review of Multimodal Data Acquisition Approaches for Brain–Computer Interfaces

  • Sayantan Ghosh,
  • Domokos Máthé,
  • Purushothaman Bhuvana Harishita,
  • Pramod Sankarapillai,
  • Anand Mohan,
  • Raghavan Bhuvanakantham,
  • Balázs Gulyás and
  • Parasuraman Padmanabhan

2 December 2024

There have been multiple technological advancements that promise to gradually enable devices to measure and record signals with high resolution and accuracy in the domain of brain–computer interfaces (BCIs). Multimodal BCIs have been able to ga...

  • Article
  • Open Access
2 Citations
2,987 Views
11 Pages

8 February 2024

Hardening of arterial walls associated with elevated postprandial blood glucose levels increases the risk of cardiovascular disease; however, the impact of intermittent aerobic training on reducing arterial stiffness is unknown. The aim of this study...

  • Article
  • Open Access
2 Citations
10,178 Views
11 Pages

7 April 2024

Practitioners routinely use the single leg heel raise (SLHR) to quantify calf function in healthy and injured populations. Despite this, approaches vary and the impact of cueing on SLHR performance and results interpretation in athletesis unknown. Th...

  • Brief Report
  • Open Access
2 Citations
2,245 Views
10 Pages

Manual Reduction for Subacute Osteoporotic Burst and Severe Compression Thoracolumbar Fractures

  • Kung-Chia Li,
  • Ching-Hsiang Hsieh,
  • Ting-Hua Liao and
  • Chih-Hung Chen

24 May 2024

The objective of this study was to retrospectively assess the impact of manual reduction (MR) on patients with subacute osteoporotic thoracolumbar burst fractures and severe compression fractures (OTLBFSCFs). From January 2016 to May 2020, 101 cases...

  • Article
  • Open Access
2 Citations
2,585 Views
16 Pages

Simplified Cost Functions Meet Advanced Muscle Models to Streamline Muscle Force Estimation

  • Muhammad Hassaan Ahmed,
  • Jacques-Ezechiel N’Guessan,
  • Ranjan Das,
  • Matthew Leineweber and
  • Sachin Goyal

19 September 2024

Background/Objectives: This study explores an optimization-based strategy for muscle force estimation by employing simplified cost functions integrated with physiologically relevant muscle models. Methods: Considering elbow flexion as a case study, w...

  • Article
  • Open Access
2 Citations
3,541 Views
19 Pages

2 August 2024

The increasing use of e-cigarettes (ECs) has raised public health concerns due to the observed cytotoxic effects in both in vitro and in vivo studies. Infants and young children, being particularly vulnerable groups, exhibit heightened susceptibility...

  • Review
  • Open Access
2 Citations
5,978 Views
12 Pages

The Current Role of Collagen Patch Augmentation in Rotator Cuff Pathology: A Narrative Review

  • Wen Hon Darren Wee,
  • Zhi Wei Nicholas Matthias Tan,
  • Clara X. Quek,
  • Jing Hui Yik and
  • Sean Wei Loong Ho

23 August 2024

Rotator cuff repair is a common orthopaedic procedure. Despite advancements in the mechanics of rotator cuff repair, the re-tear rate post repair remains significant. This review assesses the available literature on usage of collagen bio-inductive sc...

  • Review
  • Open Access
2 Citations
5,174 Views
12 Pages

Neurocysticercosis—Diagnostic Mystery: Current Status for Europe

  • Mikołaj Hurła,
  • Damian Pikor,
  • Klaudia Kościelecka,
  • Alicja Drelichowska,
  • Natalia Banaszek and
  • Małgorzata Paul

29 August 2024

Neurocysticercosis (NCC), a parasitic infection of the central nervous system caused by the larval stage of Taenia solium, presents a diagnostic conundrum due to its rare and often nonspecific clinical manifestations. This paper aims to unravel the d...

  • Article
  • Open Access
2 Citations
3,364 Views
11 Pages

9 October 2024

Background: Muscle biopsy, the gold standard for assessing muscle aerobic capacity, is an invasive procedure. Noninvasive alternatives, such as 31-phosphorus magnetic resonance spectroscopy (31P-MRS) and near-infrared spectroscopy (NIRS), provide val...

  • Article
  • Open Access
2 Citations
2,304 Views
14 Pages

13 June 2024

Existing implants used with Total Knee Arthroplasty (TKA), Total Hip Arthroplasty (THA), and other joint reconstruction treatments, have displayed premature failures and frequent needs for revision surgery in recent years, particularly with young act...

  • Article
  • Open Access
2 Citations
2,587 Views
18 Pages

14 June 2024

Prostate and bladder cancer treatments have several challenges, including intense side effects and mechanisms of resistance. Thus, it is urgent to find drugs that can fill these gaps. For this purpose, Entecavir (ETV) was tested alone and in combinat...

  • Article
  • Open Access
2 Citations
3,171 Views
13 Pages

Signs of Alveolar Collapse in Idiopathic Pulmonary Fibrosis, Hypersensitivity Pneumonitis and Systemic Sclerosis Revealed by Inspiration and Expiration Computed Tomography

  • Marco Fabian Wittwer,
  • Soung-Yung Kim,
  • Alexander Leichtle,
  • Sabina Berezowska,
  • Sabina A. Guler,
  • Thomas Geiser,
  • Johannes Heverhagen,
  • Britta Maurer and
  • Alexander Poellinger

7 November 2023

Idiopathic pulmonary fibrosis (IPF), hypersensitivity pneumonitis (HP) and systemic sclerosis (SSc) are among the most common entities that cause pulmonary fibrosis. Alveolar collapse with subsequent collapse induration of lung tissue is thought to c...

  • Article
  • Open Access
2 Citations
2,408 Views
10 Pages

Clinical Characteristics, Outcomes, and Risk Factors of Patients Hospitalized for COVID-19 across the Latest Pandemic Waves: Has Something Changed?

  • Mariacristina Poliseno,
  • Edoardo Paolo Drago,
  • Melita Anna Poli,
  • Maurantonio Altamura,
  • Serena Rita Bruno,
  • Angela Calamo,
  • Anna Giannelli,
  • Giovanni Infante,
  • Michele Mazzola and
  • Sergio Carbonara
  • + 3 authors

30 May 2023

Despite the availability of vaccines and antivirals and the biological evolution of SARS-CoV-2, the rate of hospitalizations and deaths from COVID-19 remains high in Italy. It is crucial to understand whether and how the clinical characteristics of p...

  • Communication
  • Open Access
2 Citations
1,809 Views
8 Pages

A Longitudinal Assessment of Substance Use Treatment during the COVID-19 Pandemic Using Staff and Service Data

  • Molly Carlyle,
  • Grace Newland,
  • Leith Morris,
  • Rhiannon Ellem,
  • Calvert Tisdale,
  • Catherine A. Quinn and
  • Leanne Hides

4 April 2023

Introduction: Alcohol and other drug (AOD) treatment services were required to rapidly adapt delivery of care in response to the coronavirus (COVID-19) pandemic. This study examined longitudinal changes in the delivery of AOD counselling in Australia...

  • Article
  • Open Access
2 Citations
10,427 Views
11 Pages

Prevalence and Factors Influencing Self-Medication among Pregnant Women Attending Antenatal Clinics in Urban Tertiary Hospitals in Nigeria

  • Clement Kevin Edet,
  • Anthony Ike Wegbom,
  • Kitoye Gentle Samuel,
  • Leesi Sapira-Ordu,
  • Ishmeal Daniel Jaja,
  • Janet Ene-Peter,
  • Isaac Harold,
  • Chinemere Onyema,
  • Biteegeregha Godfrey Pepple and
  • Adeniyi Francis Fagbamigbe

10 March 2023

Despite the adverse effects of self-medication (SM), such as antimicrobial drug resistance, drug addiction, allergy, worsening of ailment, organ damage, disability, and death, the practice is still common and increasingly practiced globally, even amo...

  • Review
  • Open Access
2 Citations
11,629 Views
17 Pages

20 February 2023

The acute rupture of the Achilles tendon is an increasingly common injury due to an active lifestyle and participation in sports, especially in the middle-aged group. We conducted a focused review of the literature and found that the acute rupture of...

  • Review
  • Open Access
2 Citations
3,746 Views
28 Pages

2 September 2025

Monkeypox (Mpox), a re-emerging zoonotic disease, has garnered global attention due to its evolving epidemiology, diverse clinical manifestations, and significant public health impact. The rapid international spread of the Mpox prompted the World Hea...

  • Article
  • Open Access
2 Citations
3,626 Views
49 Pages

Single-Eye Porcine Retinal Pigment Epithelium Cell Cultures—A Validated and Reproducible Protocol

  • Philipp Dörschmann,
  • Justine Wilke,
  • Nina Tietze,
  • Johann Roider and
  • Alexa Klettner

10 February 2025

Background: Age-related macular degeneration (AMD) is the leading cause of severe vision loss in industrialized nations. AMD models based on standardized optimized cell culture models are warranted. The aim of this study is to implement a standard op...

  • Article
  • Open Access
2 Citations
3,945 Views
18 Pages

Decreased Effectiveness of a Novel Opioid Withdrawal Protocol Following the Emergence of Medetomidine as a Fentanyl Adulterant

  • Kory S. London,
  • Philip Durney,
  • TaReva Warrick-Stone,
  • Karen Alexander and
  • Jennifer L. Kahoud

23 May 2025

Background/Objectives: Philadelphia has experienced a surge in illicit fentanyl adulterated with alpha-2 agonist sedatives. Initially, xylazine (“tranq”) was the predominant adulterant, and a novel multimodal withdrawal protocol was effec...

  • Case Report
  • Open Access
2 Citations
2,601 Views
6 Pages

Inflammatory Bowel Disease in Activated PI3Kδ Syndrome: An Uncommon Complication of a Rare Condition

  • Vanessa Nadia Dargenio,
  • Vincenzo Rutigliano,
  • Baldassarre Martire,
  • Bénédicte Pigneur,
  • Costantino Dargenio,
  • Ruggiero Francavilla and
  • Fernanda Cristofori

12 November 2024

Background/Objectives: Monogenic primary immunodeficiencies represent a group of disorders with varying levels of severity, many of which remain poorly understood. Activated phosphoinositide-3 kinase delta syndrome (APDS) is a rare genetic condition...

  • Article
  • Open Access
1 Citations
4,281 Views
19 Pages

Green Synthesis of Cocos nucifera-Based Nanomaterials and Mechanistic Basis of Their Antimicrobial Action

  • Zuriatou Yajeh Tanka,
  • Naphtali Odogu Ankoro,
  • Vincent Ngouana,
  • Franklin Loïc Tchinda Taghu,
  • Abongta Lum Mforbesi,
  • Branly-Natalien Nguena-Dongue,
  • Julius Nsami Ndi,
  • Boniface Pone Kamdem,
  • Paul Keilah Lunga and
  • Fabrice Fekam Boyom

6 March 2024

Caused by pathogenic microorganisms, infectious diseases are known to cause high mortality rates, severe burdens of disability, and serious worldwide aftermaths. Drug-resistant pathogens have reduced the efficacy of available therapies against these...

  • Article
  • Open Access
1 Citations
5,347 Views
9 Pages

Increased Risk for Non-Union in First Metatarsophalangeal Joint Arthrodesis following High-Velocity Reaming: A Retrospective Study

  • Assaf Albagli,
  • Assaf Kadar,
  • Ron Gurel,
  • Elchanan Luger,
  • Yaniv Warschawski and
  • Shai Factor

26 February 2024

Objective: Arthrodesis of the first metatarsophalangeal joint (MTPJ) is a reliable procedure for treating various pathologies related to this joint. However, non-union is a common and debilitating complication of the procedure. The purpose of this st...

  • Opinion
  • Open Access
1 Citations
2,958 Views
6 Pages

25 September 2024

Background. The COVID-19 pandemic introduced unprecedented social distancing measures, resulting in significant deprivation of physical contact. Objective. This opinion article explores the implications of this tactile deprivation on psychological we...

  • Article
  • Open Access
1 Citations
2,803 Views
15 Pages

The Relationship between Vitamin D and TyG Index in Prediabetes and Type 2 Diabetes Mellitus among an Indian Tribal Community: A Cross-Sectional Study

  • Roshan Kumar Mahat,
  • Prasanna Kumar Rathor,
  • Vedika Rathore,
  • Manisha Arora,
  • Suchismita Panda and
  • Gujaram Marndi

8 October 2024

Background: Vitamin D deficiency is thought to increase the likelihood of insulin resistance (IR) and diabetes onset. The objective of this study was to examine the association between the triglyceride glucose (TyG) index and vitamin D levels in indi...

  • Article
  • Open Access
1 Citations
3,447 Views
12 Pages

18 September 2024

Antiretroviral treatment (ART) has revolutionized the management of the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS), enabling long-term viral load (VL) suppression in patients. Despite the proven effectiveness of...

  • Article
  • Open Access
1 Citations
3,420 Views
15 Pages

Comprehensive Analysis of the Genetic Variation in the LPA Gene from Short-Read Sequencing

  • Raphael O. Betschart,
  • Georgios Koliopanos,
  • Paras Garg,
  • Linlin Guo,
  • Massimiliano Rossi,
  • Sebastian Schönherr,
  • Stefan Blankenberg,
  • Raphael Twerenbold,
  • Tanja Zeller and
  • Andreas Ziegler

4 June 2024

Lipoprotein (a) (Lp(a)) is a risk factor for cardiovascular diseases and mainly regulated by the complex LPA gene. We investigated the types of variation in the LPA gene and their predictive performance on Lp(a) concentration. We determined the Kring...

  • Interesting Images
  • Open Access
1 Citations
2,155 Views
5 Pages

Obliterative Endotheliitis Leading to Cystic Lung Necrosis in Severe COVID-19 during the First Wave of the Pandemic

  • Clémence Delteil,
  • Julien Carvelli,
  • Lionel Velly,
  • Laurent Daniel,
  • Caroline Capuani,
  • Julia Torrents,
  • Marc Gainnier,
  • Nicolas Bruder,
  • Marie-Dominique Piercecchi-Marti and
  • Pierre Simeone

23 March 2023

In the early months of the outbreak (2020–2022), COVID-19 was responsible for acute respiratory distress syndrome (ARDS) and an exceptional number of intensive care unit (ICU) admissions. Weaning difficulties from invasive mechanical ventilatio...

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BioMed - ISSN 2673-8430