Special Issues

Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Personalized Medicine of Cancers
edited by
submission deadline 28 Feb 2025 | 3 articles | Viewed by 5099 | Submission Open
Keywords: personalized medicine; biomarkers; genomics; proteomics; personalized oncology
(This special issue belongs to the Section Molecular Cancer Biology)
PET/CT in Cancers Outcomes Prediction
edited by Ahmad Shariftabrizi
submission deadline 28 Feb 2025 | 3 articles | Viewed by 3985 | Submission Open
Keywords: FDG PET/CT; PSMA PET/CT; dotatate PET/CT; tumor heterogeneity; radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy; targeted therapy; PET physics; radiotracer metabolism
(This special issue belongs to the Section Methods and Technologies Development)
The Extracellular Matrix in Cancer Ecosystems: Functional Contributions and Targeting Opportunities
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 3390 | Submission Open
Keywords: extracellular matrix; cancer; tumor microenvironment; metastasis niche; matrix remodeling; biomedical bioengineering; matrix-derived biomarkers; therapeutic matrix targeted approach; matrix-based tumor models
(This special issue belongs to the Section Tumor Microenvironment)
New Insights in Mammographic Density in Breast Cancer Risk, Screening and Detection
edited by
submission deadline 28 Feb 2025 | 3 articles | Viewed by 3090 | Submission Open
Keywords: breast cancer; mammographic density; breast cancer risk; breast cancer screening; mammography; risk reduction; consumer-led research; multi-disciplinary research
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Mesothelioma—from Diagnosis to Treatment
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 2991 | Submission Open
Keywords: asbestos; BAP-1; CAR-T; CTLA-4; immunotherapy; mesothelioma; PD-1; PD-L1
(This special issue belongs to the Section Cancer Therapy)
Gaps in Cancer Cachexia Research
edited by Jose M. Garcia and
submission deadline 28 Feb 2025 | 2 articles | Viewed by 2201 | Submission Open
Keywords: cancer cachexia; physical function; innovative models; rehabilitation; patient-reported outcomes; gender; aging; skeletal muscle; brain; adipose tissue
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Clinical and Surgical Outcomes in the Management of Extremity Soft Tissue Sarcomas
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 1879 | Submission Open
Keywords: soft tissue sarcoma; outcome; limb salvage; radiotherapy; surgery
(This special issue belongs to the Section Cancer Therapy)
Advances in Acidosis within the Tumor Microenvironment submission deadline 28 Feb 2025 | 1 articles | Viewed by 1066 | Submission Open
(This special issue belongs to the Section Tumor Microenvironment)
Intraoperative Visualization Techniques and Advanced Imaging in Brain Tumors submission deadline 28 Feb 2025 | 1 articles | Viewed by 877 | Submission Open
Keywords: glioma; glioblastoma; brain metastasis; diffusion tensor imaging; fiber tracking; functional MRI; intraoperative fluorescence; intraoperative MRI; intraoperative ultrasound
(This special issue belongs to the Section Methods and Technologies Development)
Treg Cell Immunotherapy in Cancer
edited by
submission deadline 28 Feb 2025 | Viewed by 570 | Submission Open
Keywords: treg cells; cancer immunotherapy; immune evasion; antitumor immune responses; targeting therapeutic interventions
(This special issue belongs to the Section Cancer Therapy)
Hematologic Malignancies and Related Disorders: Challenges from Diagnosis to Treatment submission deadline 28 Feb 2025 | 1 articles | Viewed by 535 | Submission Open
Keywords: hematopoietic cell transplantation; cell therapy; acute myeloid leukemia; graft-versus-host disease; hematologic malignancies; thrombosis; complement; lymphoma; myeloma; COVID-19
(This special issue belongs to the Section Cancer Therapy)
Endometrial Cancer Prevention, Early Diagnosis and Treatment: Advances and Challenges
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 293 | Submission Open
Keywords: endometrial cancer; gynaecologic oncology; surgery; prevention; early diagnosis; advanced therapy; molecular classification; biomarkers
(This special issue belongs to the Section Cancer Therapy)
Robotic Surgery for Gastrointestinal (GI) Malignancies submission deadline 28 Feb 2025 | Viewed by 272 | Submission Open
Keywords: robotic surgery; colorectal cancer; gastric cancer; liver cancer; pancreatic cancer; esophageal cancer; robotic platform
(This special issue belongs to the Section Clinical Research of Cancer)
The Role of Apoptosis and Autophagy in Cancer
edited by
submission deadline 28 Feb 2025 | Viewed by 213 | Submission Open
Keywords: apoptosis; cell death; tumor
(This special issue belongs to the Section Molecular Cancer Biology)
Monoclonal Antibodies in Lymphoma
edited by Donato Mannina
submission deadline 28 Feb 2025 | Viewed by 186 | Submission Open
Keywords: monoclonal antibodies; immunotherapy; drug immunoconiugates; bispecific antibodies; checkpoints inhibitors; NHL; HL; CLL
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Advances in Bladder Preservation Approaches for Bladder Cancer (Volume II)
edited by and Todd A. Yezefski
submission deadline 28 Feb 2025 | Viewed by 142 | Submission Open
Keywords: bladder cancer; bladder preservation; trimodality therapy; chemoradiation; immunotherapy; intravesical therapy; BCG refractory or unresponsive
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Cell Migration and Invasion in Cancer
edited by
submission deadline 28 Feb 2025 | Viewed by 140 | Submission Open
Keywords: cell migration; invasion; tumor; metastasis; genes; microRNA
(This special issue belongs to the Section Molecular Cancer Biology)
Cell Therapy in Solid Cancers: Current and Future Landscape
edited by Wenwee Ma, Jan Joseph Melenhorst and Li Yin
submission deadline 28 Feb 2025 | Viewed by 120 | Submission Open
Keywords: cell therapy; solid tumors; immunotherapy; CAR-T; NK cell
(This special issue belongs to the Section Cancer Therapy)
New Insights into Cell Death and Drug Resistance in Cancer
edited by
submission deadline 28 Feb 2025 | Viewed by 106 | Submission Open
Keywords: cancer; chemotherapy; cell death; drug resistance; signal transduction pathways
(This special issue belongs to the Section Molecular Cancer Biology)
Radioligand Therapy in Cancer
edited by Ahmad Shariftabrizi
submission deadline 28 Feb 2025 | Viewed by 88 | Submission Open
Keywords: PSMA and SSTR targeting radiopharmaceuticals; old and novel targets for radioligand therapy; dosimetry; toxicity evaluation and reduction; machine learning and artificial intelligence in radionuclide therapy; novel radiopharmaceutical; regulatory aspects of radioligand therapy; patient selection optimization; radioligand therapy for neuroblastoma and other pediatric malignancies
(This special issue belongs to the Section Cancer Therapy)
Cancer Survivorship: During and after Treatment
edited by Florian Scotte
submission deadline 28 Feb 2025 | Viewed by 83 | Submission Open
Keywords: cancer survivorship; treatment effects; quality of life; palliative care; cancer management
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Cutting-Edge Innovations and Clinical Impact of CAR-Based Cancer Immunotherapy
edited by , Ezhilarasi Chendamarai and
submission deadline 28 Feb 2025 | Viewed by 74 | Submission Open
Keywords: cancer immunotherapy; adoptive cell therapy (ACT); chimeric antigen receptor (CAR); T-cells; macrophages; monocytes; NK cells; dendritic cells; Treg; immunoinformatics
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Novel Perspectives in Nasopharyngeal Carcinoma submission deadline 28 Feb 2025 | Viewed by 70 | Submission Open
Keywords: nasopharynx; nasopharyngeal cancer; Epstein– Barr virus; pathology; carcinoma; endoscopic nasopharyngectomy
(This special issue belongs to the Section Cancer Therapy)
Innovations in Soft Tissue Sarcoma Diagnosis and Treatment (2nd Edition)
edited by Erlinda M. Gordon, and Frederick L. Hall
submission deadline 28 Feb 2025 | Viewed by 49 | Submission Open
Keywords: soft tissue sarcoma; gene therapy; natural killer cell therapy; immune and cell cycle checkpoint inhibitors; targeted therapy
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Recent Advances in Orthopaedic Oncology: 2nd Edition
edited by
submission deadline 28 Feb 2025 | Viewed by 32 | Submission Open
Keywords: bone and soft tissue sarcomas; orthopaedic oncology; benign tumours; giant cell tumours; solitary bone tumours; desmoid tumours
(This special issue belongs to the Section Cancer Therapy)
New Insights in Nanomedicine and Targeted Drugs for Breast Cancer
edited by , Gennaro Sanità, Alessandro Venuta and Rosarita Nasso
submission deadline 28 Feb 2025 | Viewed by 29 | Submission Open
Keywords: breast cancer; nanoparticles; active targeting; BC; nanomedicine
(This special issue belongs to the Section Cancer Drug Development)
Unlocking the Potential of AI and Big Data in Cancer Research: Advances and Applications submission deadline 1 Mar 2025 | 10 articles | Viewed by 16347 | Submission Open
Keywords: oncology; artificial intelligence; machine learning; radiology; radiotherapy; genomics; transcriptomics; data analysis; data science; deep learning; autosegmentation
(This special issue belongs to the Section Cancer Informatics and Big Data)
Developments in the Management of Gastrointestinal Malignancies
edited by Zachary J. Brown
submission deadline 1 Mar 2025 | 9 articles | Viewed by 10743 | Submission Open
Keywords: gastrointestinal malignancies; multimodal therapy; chemotherapy; radiotherapy; immunotherapy; localized and metastatic
(This special issue belongs to the Section Cancer Therapy)
Urologic Cancer: Endoscopic, Laparoscopic, and Robot-Assisted Surgery Management
edited by Kouji Izumi
submission deadline 1 Mar 2025 | 5 articles | Viewed by 8213 | Submission Open
Keywords: prostate cancer; urothelial cancer; kidney cancer; adrenal cancer; transurethral technique; ureteroscopy; ureteral stent  
(This special issue belongs to the Section Methods and Technologies Development)
Novel Developments in Invasive Lobular Breast Cancer: Diagnosis, Prognosis and Therapy submission deadline 1 Mar 2025 | 3 articles | Viewed by 4769 | Submission Open
Keywords: invasive lobular carcinoma; imaging; diagnosis; pathology; tumor microenvironment; treatment; metastasis
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in the Treatment of Hepatocellular Carcinoma
edited by
submission deadline 1 Mar 2025 | 3 articles | Viewed by 3274 | Submission Open
Keywords: hepatocellular carcinoma; molecular targeted drugs; immune checkpoint inhibitors; sequential therapy; conversion therapy; immune microenvironment
(This special issue belongs to the Section Cancer Therapy)
Advancements in the Diagnosis and Surgical Treatment of Prostate Cancer
edited by and Christian Thomas
submission deadline 1 Mar 2025 | Viewed by 226 | Submission Open
Keywords: robotic-assisted radical prostatectomy; significance of pelvic lymph node dissection in the context of radical prostatectomy; complications of surgical therapy for prostate cancer; magnetic resonance imaging/ultrasound-guided target biopsy of the prostate; comparison of various robotic systems for radical prostatectomy; learning curves; hospital volume; prostate cancer centers
(This special issue belongs to the Section Clinical Research of Cancer)
The Role of Regucalcin in Cancer submission deadline 1 Mar 2025 | Viewed by 84 | Submission Open
Keywords: cancer suppressor protein; cell signaling; metabolic regulation; transcription factor; cell proliferation; cell death; drug development; cancer therapy
(This special issue belongs to the Section Tumor Microenvironment)
Recent Advances in the Molecular Genetics of Sarcomas
edited by Wei Jiang
submission deadline 1 Mar 2025 | Viewed by 82 | Submission Open
Keywords: sarcoma; bone and soft tissue; molecular genetics; molecular pathology; classification
(This special issue belongs to the Section Molecular Cancer Biology)
Overcoming Chemoresistance in Cancer: Identifying Biomarkers and Novel Targets submission deadline 1 Mar 2025 | Viewed by 38 | Submission Open
Keywords: cancer treatment; chemoresistance; tumor microenvironment; cancer signaling pathways; targeted therapy; personalized anti-cancer therapies; biomarker; anti-cancer drug response prediction
(This special issue belongs to the Section Cancer Therapy)
Irreversible Electroporation for Liver Metastases from Colorectal Cancer
edited by Ajith K. Siriwardena and
submission deadline 5 Mar 2025 | Viewed by 102 | Submission Open
Keywords: irreversible electroporation; colorectal cancer; liver metastases; ablation; non-thermal ablation; international survey
(This special issue belongs to the Section Cancer Metastasis)
Surgical Advances in the Treatment of Gliomas: Preserving Function and Quality of Life
edited by Francesco Vergani and José Pedro Lavrador
submission deadline 7 Mar 2025 | Viewed by 75 | Submission Open
Keywords: neuro-oncology; brain mapping; neuroimaging; intraoperative neuro-monitoring; functional MRI; transcranial magnetic stimulation; neurorehabilitation
(This special issue belongs to the Section Cancer Therapy)
New Strategies in Diagnosis and Treatments for Brain Tumors (Volume II)
edited by Sven Rainer Kantelhardt
submission deadline 10 Mar 2025 | 3 articles | Viewed by 4863 | Submission Open
Keywords: glioma; brain tumor; molecular guided therapy; personal medicine; radiomics; digital analysis; artificial intelligence; intraoperative imaging; surgical resection
(This special issue belongs to the Section Cancer Therapy)
Socio-Demographic Factors and Cancer Research
edited by and Amanda N. Goldin
submission deadline 10 Mar 2025 | 2 articles | Viewed by 3363 | Submission Open
Keywords: socioeconomic disparity; cancer delivery; cancer survival; metastatic cancer; culture-specific cancer outcomes; AI; machine learning
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Recent Developments in Proton Therapy of Head and Neck Cancer
edited by and Irini Youssef
submission deadline 10 Mar 2025 | Viewed by 116 | Submission Open
Keywords: head and neck; intensity-modulated proton radiation; particle therapy; toxicity; outcomes
(This special issue belongs to the Section Cancer Therapy)
Upper Tract Urothelial Carcinoma: Current Knowledge and Perspectives
edited by Katie S. Murray and Saum Ghodoussipour
submission deadline 10 Mar 2025 | Viewed by 31 | Submission Open
Keywords: upper tract urothelial carcinoma; upper tract disease; urothelial cell carcinoma
(This special issue belongs to the Section Cancer Therapy)
Clinical Outcomes in Urologic Cancers
edited by and Pierre Karakiewicz
submission deadline 15 Mar 2025 | 11 articles | Viewed by 10325 | Submission Open
Keywords: bladder cancer; prostate cancer; kidney cancer; upper tract urothelial carcinoma; adrenocortical cancer
(This special issue belongs to the Section Clinical Research of Cancer)
Tumor Microenvironment of Breast Cancer
edited by
submission deadline 15 Mar 2025 | 4 articles | Viewed by 6428 | Submission Open
Keywords: breast cancer; tumor microenvironment; TME; stromal cells
(This special issue belongs to the Section Tumor Microenvironment)
Current Status and Clinical Developments in Lung Cancer: What to Expect from Emerging Drugs? submission deadline 15 Mar 2025 | 2 articles | Viewed by 5748 | Submission Open
Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors (ICIs); target therapy; tyrosine kinase inhibitors (TKIs); cancer biomarkers
(This special issue belongs to the Section Cancer Therapy)
Mechanisms of Therapy Resistance in Cancers
edited by
submission deadline 15 Mar 2025 | 2 articles | Viewed by 3669 | Submission Open
Keywords: ATP-binding cassette transporters; cancer stem cells; extracellular ATP; repair of DNA damage; immunotherapy resistance
(This special issue belongs to the Section Cancer Drug Development)
Study on Epidemiology of Childhood Cancer
edited by Francesco Giusti and
submission deadline 15 Mar 2025 | 1 articles | Viewed by 1876 | Submission Open
Keywords: childhood cancer; epidemiology; childhood cancer registries; incidence; prevalence; mortality; survival; time trends; special analysis; environmental factors; perinatal factors; inequalities
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Epidermal Growth Factor Receptor-Driven Non-Small-Cell Lung Cancer: Diagnostic Technologies and Therapeutic Strategies
edited by
submission deadline 15 Mar 2025 | Viewed by 171 | Submission Open
Keywords: EGFR-targeted therapy; non-small-cell lung cancer diagnosis; diagnostic technologies and devices; biological discoveries in NSCLC; AI-assisted diagnosis in oncology; clinical practice in NSCLC detection; therapeutic– diagnostic integration; early-stage lung cancer monitoring; advanced NSCLC diagnostic approaches; precision medicine in lung cancer
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Ovarian Cancer Treatment: Past, Present and Future
edited by Dimitrios Tsolakidis and Dimitrios Zouzoulas
submission deadline 15 Mar 2025 | Viewed by 89 | Submission Open
Keywords: ovarian cancer; cytoreductive surgery; HIPEC; chemotherapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Targeted Drugs in Chronic Lymphocytic Leukemia 2nd Edition
edited by
submission deadline 15 Mar 2025 | Viewed by 63 | Submission Open
Keywords: CLL; targeted therapies; precision therapy; B-cell; BTK; BCL2; PI3K; SYK
(This special issue belongs to the Section Cancer Drug Development)
Endoscopic Ultrasound Tissue Acquisition in Abdominal Malignancies submission deadline 15 Mar 2025 | Viewed by 59 | Submission Open
Keywords: FNB; EUS; cancer; pancreas; accuracy
(This special issue belongs to the Section Methods and Technologies Development)
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