Special Issues

Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Locally Advanced and Metastatic Kidney Cancer
edited by and
submission deadline 15 Apr 2025 | Viewed by 385 | Submission Open
Keywords: kidney cancer; renal cell carcinoma; locally advanced; oligometastatic; metastatic; novel therapeutics; diagnostic imaging; biomarkers; multimodal treatment; cytoreductive nephrectomy
(This special issue belongs to the Section Cancer Metastasis)
Updates in Neuroendocrine Neoplasms
edited by Jonathan Strosberg
submission deadline 15 Apr 2025 | Viewed by 170 | Submission Open
Keywords: neuroendocrine tumors; neuroendocrine neoplasms; neuroendocrine carcinomas; therapy; germline mutations; somatic mutations
(This special issue belongs to the Section Cancer Therapy)
Advances in Imaging Techniques of Molecular Oncology
edited by
submission deadline 15 Apr 2025 | Viewed by 89 | Submission Open
Keywords: cancer; oncological imaging; molecular imaging; SPECT/TC; PET/CT; PET/MRI; DWI; DCE-MRI; nanotheranostics; artificial intelligence; radiomics; theranostics
(This special issue belongs to the Section Molecular Cancer Biology)
Detection of Breast Cancer with Mammography
edited by
submission deadline 15 Apr 2025 | Viewed by 82 | Submission Open
Keywords: mammography; breast cancer detection; imaging technologies; artificial intelligence; radiomics
(This special issue belongs to the Section Methods and Technologies Development)
Clinical Pathology of Lung Cancer
edited by
submission deadline 15 Apr 2025 | Viewed by 80 | Submission Open
Keywords: lung cancer; pathology; diagnosis; treatment; targeted therapies; immunotherapy
(This special issue belongs to the Section Cancer Pathophysiology)
Novel Approaches to Gynecologic Cancers Biology and Treatment: 2nd Edition
edited by Marcin Bobiński and Monika Abramiuk
submission deadline 15 Apr 2025 | Viewed by 3 | Submission Open
Keywords: ovarian cancer; endometrial cancer; cervical cancer; targeted therapy; tumor immunity; tumor microenvironment; gynecological surgery; gynecologic oncology
(This special issue belongs to the Section Cancer Therapy)
Advances in the Research and Treatment of Pancreatic Cancer
edited by
submission deadline 18 Apr 2025 | Viewed by 48 | Submission Open
Keywords: pancreatic cancer; pancreatic surgery; neoadjuvant chemotherapy; treatment
(This special issue belongs to the Section Cancer Therapy)
Oncoplastic Techniques and Mastectomy in Breast Cancer
edited by Giovanni Papa
submission deadline 20 Apr 2025 | 2 articles | Viewed by 4848 | Submission Open
Keywords: breast cancer; breast reconstruction; mammoplasty; breast implants; acellular dermal matrix; direct-to-implant reconstruction; two-stage breast reconstruction; breast-conserving surgery
(This special issue belongs to the Section Clinical Research of Cancer)
Current Clinical Studies of Pancreatic Ductal Adenocarcinoma submission deadline 20 Apr 2025 | 5 articles | Viewed by 4052 | Submission Open
(This special issue belongs to the Section Clinical Research of Cancer)
Advancements in Child, Adolescent, and Young Adult Cancer Survivorship submission deadline 20 Apr 2025 | 1 articles | Viewed by 917 | Submission Open
Keywords: late effects; chronic diseases; prevention; rehabilitation; remediation; psychosocial factors; quality of life; lifestyles; surveillance; survivors; educational strategies
(This special issue belongs to the Section Pediatric Oncology)
Current Progress in the Clinical Management and Basic Science of Head and Neck Cancer
edited by
submission deadline 20 Apr 2025 | Viewed by 113 | Submission Open
Keywords: head and neck cancer; immunotherapy; chemoradiotherapy; surgery; molecular biology; oncogenesis; cancer immunology
(This special issue belongs to the Section Clinical Research of Cancer)
The Advance of Clinical Pharmacology in Lung Cancer
edited by and Yen-Yi Zhen
submission deadline 20 Apr 2025 | Viewed by 70 | Submission Open
Keywords: lung cancer; target therapy; immunotherapy; antiangiogenic agent; chemotherapy; NGS
(This special issue belongs to the Section Clinical Research of Cancer)
Symptom Burden in Cancer: Assessment and Management
edited by Sam M. Salek, and Tatyana Ionova
submission deadline 20 Apr 2025 | Viewed by 44 | Submission Open
Keywords: symptom burden; patient-reported outcomes; symptom assessment; symptom management; quality of life
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advances in Metastatic Prostate Cancer
edited by
submission deadline 21 Apr 2025 | 1 articles | Viewed by 1514 | Submission Open
Keywords: prostate cancer; genomic profiling; therapeutic sequences; immunotherapy; chemotherapy; hormone-therapy; molecular imaging
(This special issue belongs to the Section Cancer Metastasis)
Clinical Applications of Integrative Analysis of Validated Somatic and Germline Genomic Results in Oncology
edited by
submission deadline 25 Apr 2025 | 1 articles | Viewed by 1541 | Submission Open
Keywords: tumor and constitutional genome integration; clinical application of somatic and germline findings; precision oncology
(This special issue belongs to the Section Molecular Cancer Biology)
Research on Early Diagnosis and Treatment of Gastric Cancer
edited by Katsunori Iijima
submission deadline 25 Apr 2025 | 1 articles | Viewed by 1468 | Submission Open
(This special issue belongs to the Section Cancer Therapy)
Research on Surgical Treatment for Ovarian Cancer
edited by Antonios Apostolos K. Tentes and Theo Panoskaltsis
submission deadline 25 Apr 2025 | Viewed by 33 | Submission Open
Keywords: ovarian cancer; surgical; cancer treatment
(This special issue belongs to the Section Cancer Therapy)
PD-1/PD-L1 Immune Checkpoint Therapy: From Predictive Biomarkers to Noninvasive Imaging 2nd Edition submission deadline 25 Apr 2025 | Viewed by 25 | Submission Open
Keywords: PD-1; PD-L1; anti-cancer immune response; immune checkpoint; immunotherapy; biomarker; immuno-PET radiotracers; drug combinations
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Advances in Brachytherapy in the Treatment of Tumors
edited by
submission deadline 30 Apr 2025 | 6 articles | Viewed by 13321 | Submission Open
Keywords: brachytherapy; LDR; HDR; PDR; cervical cancer; prostate cancer; breast cancer
(This special issue belongs to the Section Cancer Therapy)
Novel Therapeutic Strategies in Salivary Gland Tumor submission deadline 30 Apr 2025 | 4 articles | Viewed by 5296 | Submission Open
Keywords: parotid gland; parotid tumors; facial nerve; novel therapeutic options; distant metastasis; liquid biopsy; prognostic factors; parotid robotic surgery; microRNA; imaging
(This special issue belongs to the Section Cancer Therapy)
Molecular Pathology of Brain Tumors
edited by Ho-Keung NG
submission deadline 30 Apr 2025 | 6 articles | Viewed by 4484 | Submission Open
Keywords: molecular pathology; brain tumors; AI; biomarkers; histopathology
(This special issue belongs to the Section Molecular Cancer Biology)
Long-Read Sequencing in Cancer
edited by and Patrick Driguez
submission deadline 30 Apr 2025 | 1 articles | Viewed by 2351 | Submission Open
Keywords: long-read sequencing; cancer genetics; genomics; transcriptomics; methylomics; cancer research
(This special issue belongs to the Section Cancer Informatics and Big Data)
Role of Extracellular Vesicles in Cancer Progression submission deadline 30 Apr 2025 | 1 articles | Viewed by 1245 | Submission Open
Keywords: extracellular vesicles; cancer progression; tumor microenvironment; tumor– immune landscape cross-talk pre-metastatic and metastatic niches; immune surveillance; EV-based biomarkers; EV-based therapeutic development
(This special issue belongs to the Section Tumor Microenvironment)
Advancements in Molecular Research of Prostate Cancer
edited by
submission deadline 30 Apr 2025 | 1 articles | Viewed by 569 | Submission Open
Keywords: prostate cancer; molecular targets; tumor heterogeneity; targeted interception and therapies; noninvasive biomarkers; precision oncology
(This special issue belongs to the Section Molecular Cancer Biology)
Mesothelioma Epidemiology, Pathogenesis, Emerging Treatments and Pre-Clinical Models submission deadline 30 Apr 2025 | Viewed by 402 | Submission Open
Keywords: mesothelioma; epidemiology; pathogenesis; emerging treatments; risk factors; biomarkers; surgical techniques; targeted therapies; immunotherapies; pre-clinical models
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Uveal Melanoma
edited by and
submission deadline 30 Apr 2025 | Viewed by 138 | Submission Open
Keywords: uveal melanoma; eye cancer; liver metastasis; Gα q/11 mutations; BAP1; SF3B1; PRAME; dormancy; liver-directed treatment; T-cell engager
(This special issue belongs to the Section Molecular Cancer Biology)
Feature Papers in Section “Cancer Survivorship and Quality of Life” in 2024–2025 submission deadline 30 Apr 2025 | Viewed by 104 | Submission Open
Keywords: patient care; nurse education; management policy development; nursing cancer; care survivorship
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
The Roles of Deep Learning in Cancer Radiotherapy
edited by Zhen Tian
submission deadline 30 Apr 2025 | Viewed by 39 | Submission Open
Keywords: radiotherapy; deep learning; artificial Intelligence; tumor detection; image segmentation; treatment planning; outcome prediction; radiomics
(This special issue belongs to the Section Cancer Informatics and Big Data)
Precision Medicine in Lung Cancer
edited by Gang Wang and
submission deadline 30 Apr 2025 | Viewed by 32 | Submission Open
Keywords: lung cancer; biomarkers; targeted therapy; precision medicine; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Spatial, Bulk, and Cell-Type-Related Transcriptomics in Cancer Research
edited by Xinmin Li, and
submission deadline 30 Apr 2025 | Viewed by 22 | Submission Open
Keywords: translational transcriptomics; cancer research; spatial transcriptomics; drug sensitivity and responsiveness; immune checkpoint inhibitors; targeted drugs; chemotherapy; radiation therapy; cell-based therapy; anticancer vaccines
(This special issue belongs to the Section Methods and Technologies Development)
Breast Cancer Imaging: Current Trends and Future Direction (2nd Edition)
edited by
submission deadline 30 Apr 2025 | Viewed by 20 | Submission Open
Keywords: breast cancer; mammography; ultrasound; magnetic resonance imaging— MRI; molecular breast imaging; PET/CT; PET/MRI; artificial intelligence; machine learning; radiomics
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances on Imaging and Treatment of Head and Neck Cancer
edited by Yading Yuan, Vishruta A. Dumane, and Luqman Dad
submission deadline 30 Apr 2025 | Viewed by 5 | Submission Open
Keywords: head and neck cancer; medical imaging; robotic surgery; image-guided radiation therapy; proton radiotherapy; online adaptive radiotherapy; artificial intelligence; machine learning
(This special issue belongs to the Section Cancer Therapy)
The Latest Findings of the Comprehensive Management of Intrahepatic Hepatocellular Carcinoma through the Combined Use of Lenvatinib and Locoregional Therapies submission deadline 1 May 2025 | Viewed by 293 | Submission Open
Keywords: lenvatinib; hepatocellular carcinoma; transarterial chemoembolization; transarterial chemo infusion therapy; radiation therapy; radiofrequency ablation; systemic therapy; surgery; surgical resection; locoregional therapy
(This special issue belongs to the Section Cancer Therapy)
Rare Tumors in Children: Trends in Diagnosis, Treatment and Prevention (Volume II) submission deadline 1 May 2025 | Viewed by 135 | Submission Open
Keywords: pediatric oncology; pediatric drugs; clinical pharmacology
(This special issue belongs to the Section Pediatric Oncology)
Lynch Syndrome (HNPCC): Symptoms, Causes, and Outlooks
edited by
submission deadline 1 May 2025 | Viewed by 71 | Submission Open
Keywords: Lynch syndrome; genotype– phenotype correlation; highly immunogenic frame-shift neo-peptides; immunotherapy; mismatch repair genes; unclassified genetic variants; new role of MMR proteins; miRNAs; functional assay MMR deficiency
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Identification and Clinical Application of Immunological Receptors Targeting Mutated Antigens Expressed by Solid Tumors (Volume II)
edited by
submission deadline 5 May 2025 | 1 articles | Viewed by 1901 | Submission Open
Keywords: TCR  ; CAR  ; solid tumors  ; mutated antigens  ; clinical trials
(This special issue belongs to the Section Molecular Cancer Biology)
Surgical Treatment of Abdominal Tumors
edited by and Ioannis Baloyiannis
submission deadline 10 May 2025 | Viewed by 101 | Submission Open
Keywords: abdominal; abdominal wall; tumors; surgery; cancer; malignancy; oncology; intraperitoneal; extraperitoneal
(This special issue belongs to the Section Clinical Research of Cancer)
Rehabilitation Opportunities in Cancer Survivorship
edited by and Alejandro Heredia-Ciuro
submission deadline 10 May 2025 | Viewed by 94 | Submission Open
Keywords: cancer; rehabilitation; sequelae; disability; impairment
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Novel Surgical Treatment Approaches in Advanced Gastrointestinal Neoplasms
edited by Francesco Santullo and Agostino Maria De Rose
submission deadline 10 May 2025 | Viewed by 2 | Submission Open
Keywords: advanced gastrointestinal neoplasms; colon cancer; cytoreductive surgery; gastric cancer; liver metastases; peritoneal metastases; HIPEC (hyperthermic intraperitoneal chemotherapy); PIPAC (pressurized intraperitoneal aerosol chemotherapy); pancreatic cancer
(This special issue belongs to the Section Cancer Therapy)
Infectious Agents and Cancer in Children and Adolescents
edited by and Eleni Tsotridou
submission deadline 15 May 2025 | Viewed by 105 | Submission Open
Keywords: infectious agents; immune system; tumor development; immunological memory; oncolytic viruses
(This special issue belongs to the Section Infectious Agents and Cancer)
Molecular Alterations and Targeted Therapy in Gastric Cancer submission deadline 15 May 2025 | Viewed by 103 | Submission Open
Keywords: gastric cancer; biomarker; prognosis; targeted therapy; molecular; pathway
(This special issue belongs to the Section Cancer Therapy)
The Current Status of Treatment for Oligometastatic Lung Cancer
edited by Yoshihisa Shimada
submission deadline 15 May 2025 | Viewed by 95 | Submission Open
Keywords: oligometastases; oligo-recurrence; lung cancer; local ablative therapy
(This special issue belongs to the Section Cancer Therapy)
Prostate Cancer: Molecular Imaging and Magnetic Resonance Imaging (MRI)
edited by Marco Paciotti and Davide Maffei
submission deadline 16 May 2025 | 1 articles | Viewed by 1748 | Submission Open
Keywords: prostate cancer; prostate imaging; diagnosis; clinical staging; magnetic resonance imaging (MRI); fusion biopsy; molecular imaging; positron emission tomography (PET); PSMA PET/CT; PSMA-based therapy
(This special issue belongs to the Section Methods and Technologies Development)
New Advances in the Diagnosis of Gynecological Cancer submission deadline 16 May 2025 | Viewed by 104 | Submission Open
Keywords: endometrial cancer; ovarian cancer; cervical cancer; vulvar cancer; liquid biopsy; molecular profiling; artificial intelligence and machine learning; advanced imaging modalities
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Cancer Immunotherapy: Focus on Immune Checkpoint Inhibitors and Immune Modulators
edited by
submission deadline 18 May 2025 | Viewed by 45 | Submission Open
Keywords: PD-1; PD-L1; CTLA-4; immune checkpoint molecule; immune checkpoint inhibitor; tumor microenvironment; drug resistance; biomarker; BiTE; BiCE
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Gynecologic Cancer: From Diagnosis to Treatment submission deadline 20 May 2025 | 15 articles | Viewed by 22829 | Submission Open
Keywords: endometrial cancer; cervical cancer; ovarian cancer; borderline ovarian tumor; diagnosis and treatment
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Improving Surgical Care for Patients with Hepatobiliary and Pancreatic Cancers
edited by Christopher B. Nahm and Kai M. Brown
submission deadline 20 May 2025 | 2 articles | Viewed by 3415 | Submission Open
Keywords: hepatobiliary; pancreatic; surgery; biomarkers; prognosis; treatment strategy
(This special issue belongs to the Section Cancer Therapy)
The Pathology of Biliary Tract Carcinoma (BTC)
edited by Yasuni Nakanuma
submission deadline 20 May 2025 | Viewed by 91 | Submission Open
Keywords: bile duct; gallbladder; bile ductules; precursors; preinvasive neoplasm; stem/progenitor cells; cholangiocar-cinoma; gallbladder carcinoma; pathology
(This special issue belongs to the Section Cancer Pathophysiology)
The Surgical Management of Colorectal Cancer
edited by Gyung-mo Son
submission deadline 21 May 2025 | 5 articles | Viewed by 5700 | Submission Open
Keywords: colorectal cancer; surgical management; minimally invasive surgery; laparoscopic surgery; robotic surgery; single port surgery; emergency surgery; image-guided surgery; enhanced recovery after surgery (ERAS); systemic metastasis in colorectal cancer (involving the liver; lung; peritoneum; etc.)
(This special issue belongs to the Section Cancer Therapy)
Viral Oncogenes and Their Role in Cancer Pathogenesis
edited by and Yosef Sabo
submission deadline 21 May 2025 | Viewed by 112 | Submission Open
Keywords: viral oncogenes; cancer pathogenesis; cellular regulation; tumorigenesis mechanisms; antiviral and anticancer strategies
(This special issue belongs to the Section Infectious Agents and Cancer)
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