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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Phenylketonuria (PKU): Molecular Advances in Pathophysiology and Therapies

edited by Alejandra Gamez and Sandra Brasil

submission deadline 30 Apr 2025 | 1 articles | Viewed by 4381 | Submission Open

Keywords: phenylketonuria; metabolic disease; rare disease; pharmacological chaperones; enzyme therapy; gene therapy; RNA therapy; DNAJ

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Stem Cell Biology for Cardiovascular Regeneration

edited by

Tadahisa Sugiura

submission deadline 30 Apr 2025 | 2 articles | Viewed by 4161 | Submission Open

Keywords: cardiac regenerative therapy; tissue engineering; stem cell biology; stem cell therapy; induced pluripotent stem cell

(This special issue belongs to the Section Molecular Biology)

From Biomolecules to Therapies: Bridging the Gap with Molecular Mechanisms, Computational Design, and Drug Delivery

edited by

Jesús Vicente de Julián-Ortiz

Francisco Torrens

and

Gloria Castellano

submission deadline 30 Apr 2025 | 3 articles | Viewed by 3835 | Submission Open

Keywords: biomolecules; molecular mechanisms; computational studies; drug delivery; xenobiotics

(This special issue belongs to the Section Molecular Informatics)

Natural Bioactives and Inflammation, 2nd Edition

edited by

Juan Gambini

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3190 | Submission Open

Keywords: inflammation; bioactive compounds; polyphenols; nutraceutical; diet; nutrition; pharmacology; health; lifespan; healthspan; aging; inflammaging

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Strategies to Counteract Oxidative Stress and Inflammation in Chronic-Degenerative Diseases, 3rd Edition

edited by

Cecilia Prata

Cristina Angeloni

and

Tullia Maraldi

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2763 | Submission Open

Keywords: chronic-degenerative diseases; oxidative stress; inflammation; nutrition; nutraceuticals; stem cell therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Oxidative Stress and Inflammation in the Tissue Repair—Pathways and Biotechnologies

edited by Reggiani Vilela Gonçalves and Rômulo Dias Novaes

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1726 | Submission Open

Keywords: oxidative stress; inflammasome; cytokines; angiogenesis; remodeling; molecular pathways; apoptotic alterations; diabetes; tissue repair

(This special issue belongs to the Section Biochemistry)

Metal Toxicity in Animals: Recent Insights on Physiological and Molecular Aspects

edited by

Rosaria Scudiero

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1607 | Submission Open

Keywords: heavy metals; lanthanides; physiological and molecular pathways of cellular toxicology; environmental pollution; risk assessments; risk of mixing contaminants

(This special issue belongs to the Section Molecular Toxicology)

Heart Failure Risk Factors and Therapies-Molecular Basis

edited by

Tomasz Urbanowicz

submission deadline 30 Apr 2025 | 1 articles | Viewed by 876 | Submission Open

Keywords: heart failure; risk factors; inflammatory; neutrophils; cytokines; pharmacological; therapies; molecular-based processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathophysiology and Treatment of Congenital Neuromuscular Disorders

edited by Johan Lindqvist

submission deadline 30 Apr 2025 | Viewed by 764 | Submission Open

Keywords: nemaline myopathy; hereditary neuromuscular disorder; genetic mutations; pathogenesis; pathophysiology; therapy; myofilament dysfunction; congenital neuromuscular disorders; congenital muscular dystrophy; spinal muscular atrophy; Duchenne muscular dystrophy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Diseases in Humans and Animals: From Emergence to Translational Medicine

edited by

Pawel Kordowitzki

submission deadline 30 Apr 2025 | 1 articles | Viewed by 712 | Submission Open

Keywords: animal diseases; human diseases; viruses; bacteria; translational medicine; environment; zoonosis; One Health; disease models

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Applications of Bacteriophages

edited by

Grzegorz Wegrzyn

submission deadline 30 Apr 2025 | 1 articles | Viewed by 650 | Submission Open

Keywords: bacteriophages; gene cloning; phage display technology; phage

(This special issue belongs to the Section Molecular Biology)

Unraveling Apoptosis: Deciphering Molecular Mechanisms

edited by

Gabriella Simbula

submission deadline 30 Apr 2025 | Viewed by 549 | Submission Open

Keywords: apoptosis; development; microenvironment; mitochondria dysfunction; molecular mechanisms; tumors; degenerative diseases; diabetes; metabolic diseases; neurodegenerative disease; novel pharmacological strategies

(This special issue belongs to the Section Biochemistry)

Molecular Studies in Aging, 2nd Edition

edited by

Rosa Mancinelli

submission deadline 30 Apr 2025 | 1 articles | Viewed by 500 | Submission Open

Keywords: senescence; active aging; sarcopenia; osteoporosis; oxidative stress; brain aging; cardiovascular aging

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cellular Mechanisms in Cardiomyopathy

edited by

Susan Currie

and Niall MacQuaide

submission deadline 30 Apr 2025 | Viewed by 376 | Submission Open

Keywords: E-C coupling; cardiac myocyte; cardiac fibroblast; ryanodine receptor; SERCA2a; CaMKII; phosphodiesterase

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Epilepsy

edited by Kinga Borowicz

submission deadline 30 Apr 2025 | 1 articles | Viewed by 358 | Submission Open

Keywords: epilepsy; epileptogenesis; antiepileptic drugs; drug resistance; interactions of antiepileptic drugs; multi-omics in epilepsy

(This special issue belongs to the Section Molecular Neurobiology)

Targeted Therapy of Cancer: Innovative Drugs and Molecular Tools

edited by

Rodolfo Ippoliti

and

Francesco Giansanti

submission deadline 30 Apr 2025 | Viewed by 289 | Submission Open

Keywords: drug delivery; targeted therapies; cancer therapy; molecular targets; precision medicine; molecular therapeutic targets

(This special issue belongs to the Section Molecular Oncology)

The Structures, Syntheses of Natural Products, and Their Biological Effects

edited by

Ran Jia

submission deadline 30 Apr 2025 | Viewed by 260 | Submission Open

Keywords: structures of natural products; syntheses; biological effects; biomedical applications

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research in Bamboo, Tree, Grass, and Other Forest Products

edited by Huayu Sun

submission deadline 30 Apr 2025 | Viewed by 220 | Submission Open

Keywords: bamboo; tree; grass; molecular biology; gene function

(This special issue belongs to the Section Molecular Plant Sciences)

Antimicrobial Effects and Immunological Mechanisms of Natural Products

edited by Cassio Almeida-da-Silva and Jan Martel

submission deadline 30 Apr 2025 | Viewed by 219 | Submission Open

Keywords: natural products; antimicrobial; immunology; treatment; microbiology

(This special issue belongs to the Section Molecular Microbiology)

Power Up Plant Genetic Research with Genomic Data: 3rd Edition

edited by

Hon-Ming Lam

Sachiko Isobe

and

Man-Wah Li

submission deadline 30 Apr 2025 | Viewed by 212 | Submission Open

Keywords: genome sequencing; optical mapping; genome editing; population genomics; genome-wide; association mapping; functional genomics; epigenomics; genetic interaction; chromatin; biodiversity

(This special issue belongs to the Section Molecular Genetics and Genomics)

Research on Mitochondrial Genetics and Epigenetics

edited by Arianna Montanari

submission deadline 30 Apr 2025 | Viewed by 210 | Submission Open

Keywords: mitochondrial DNA dynamics; retrograde regulation; epigenetic modulators; mitochondrial diseases; cellular homeostasis

(This special issue belongs to the Section Molecular Biology)

Advances in Molecular Insight into Neuroendocrine Cells

edited by Cristina Velazquez

submission deadline 30 Apr 2025 | Viewed by 190 | Submission Open

Keywords: calcium stores; ryanodine; autism; HNS terminals; facilitation; secretion; neurohypophysis

(This special issue belongs to the Section Molecular Neurobiology)

Biological Hallmarks and Therapeutic Strategies in Cancer

edited by Ramesh Kumar

submission deadline 30 Apr 2025 | Viewed by 182 | Submission Open

Keywords: hallmarks of cancer; cancer progression; chemotherapy; tumorigenesis; oncogenic signaling

(This special issue belongs to the Section Molecular Oncology)

Pharmacology and Toxicology of Synthetic and Natural Products

edited by

Sherif T. S. Hassan

submission deadline 30 Apr 2025 | Viewed by 178 | Submission Open

Keywords: pharmacology and toxicology; pharmacodynamics and pharmacokinetics; synthetic drugs; natural products; drug interactions; molecular mechanisms; therapeutic potential; adverse effects; dose– response relationship; drug safety and efficacy

(This special issue belongs to the Section Molecular Pharmacology)

Novel Multifunctional Materials with Electrical, Catalytic, and Biological Properties

edited by

Jana Pisk

and

Luka Pavic

submission deadline 30 Apr 2025 | Viewed by 173 | Submission Open

Keywords: novel multifunctional materials; innovative design and synthesis; electrical properties; catalytic properties; biological properties

(This special issue belongs to the Section Materials Science)

New Advances of Free-Radical Reactions in Organic Chemistry

edited by

José Justicia

submission deadline 30 Apr 2025 | Viewed by 172 | Submission Open

Keywords: free-radical reactions; organic chemistry; organic synthesis; fotoredox reactions; organometallics reactions; computational calculations; free radicals in biology; free radicals in green chemistry

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Peptides and Peptidomimetics for Targeting Protein-Protein Interactions

edited by

Giacomo Rossino

and

Pasquale Linciano

submission deadline 30 Apr 2025 | Viewed by 171 | Submission Open

Keywords: protein– protein interactions; peptide– protein interactions; interactome; proteomics; peptides; modified peptides; peptidomimetics; molecular glues; drug discovery; medicinal chemistry; rule of five; biophysical assays; molecular modelling; cancer; neurodegenerative diseases; orphan diseases; antimicrobial resistance; PROTAC

(This special issue belongs to the Section Biochemistry)

Advancing Plant Stress Science: Omics Studies for Integrated Solutions

edited by

Abdul Waheed

, Hailiang Xu and

Aishajiang Aili

submission deadline 30 Apr 2025 | Viewed by 171 | Submission Open

Keywords: multi-omics integration; stress signaling; molecular adaptation: sustainable agriculture; transcriptomics; proteomics; metabolomics; molecular signaling pathways; adaptive metabolism; sustainable agriculture

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanism in Cardiovascular Pathology

edited by Andrea Marzullo

submission deadline 30 Apr 2025 | Viewed by 168 | Submission Open

Keywords: cardiovascular diseases; molecular biology; sudden death; cardiomyopathies; heart failure; coronary artery diseases; pericarditis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Chemical and Biotechnological Strategies to Tailor the Properties of Biomaterials

edited by

Eduardo García-Junceda

and

Julia Revuelta

submission deadline 30 Apr 2025 | Viewed by 162 | Submission Open

Keywords: biomaterial functionalization; green chemistry in biomaterials; biotechnological modification; stimuli-responsive materials; translational biomaterials

(This special issue belongs to the Section Materials Science)

Emerging Trends of Quantum Mechanics, Computational Chemistry, and Spectroscopy in Physical Chemistry

edited by

Dongho Kim

submission deadline 30 Apr 2025 | Viewed by 160 | Submission Open

Keywords: quantum theory; computational chemistry; spectroscopy

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Role of Non-Coding Regulatory Elements in Human Development and Diseases

edited by

Santhilal Subhash

submission deadline 30 Apr 2025 | Viewed by 158 | Submission Open

Keywords: non-coding RNAs; epigenetics; enhancers; promoters; silencers; chromatin; genomics; microRNAs; long non-coding RNAs; cancer; disease; transcription; regulome; non-coding mutations; expression quantitative trait locus (eQTL)

(This special issue belongs to the Section Molecular Biology)

Advancing Cancer Research: Molecular Insights, Diagnostic Innovations and Therapeutic Targets

edited by Jue Wang

submission deadline 30 Apr 2025 | Viewed by 157 | Submission Open

Keywords: cancer; carcinogenesis; molecular pathology; signaling transduction; diagnosis; treatment; prognosis; pathogenesis; precision oncology; biomarker discovery; genomic profiling

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances and Perspectives of Lung Disease: 2nd Edition

edited by

Longshuang Huang

submission deadline 30 Apr 2025 | Viewed by 156 | Submission Open

Keywords: lung disease; inflammation; regeneration; infection; drug discovery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research Advances in Antibiotic Resistance

edited by

José Pascual Abad

and

Irma Marín

submission deadline 30 Apr 2025 | Viewed by 149 | Submission Open

Keywords: antibiotic resistance; resistant pathogenic microorganisms; One Health; prevalence of antibiotic-resistant microorganisms; multidrug resistance; antibiotic resistance levels; alternative anti-infectious strategies and compounds; antibiotic-resistant genes; mechanisms of antimicrobial resistance

(This special issue belongs to the Section Molecular Microbiology)

Cell Death Pathways in Immunology: Implications in Health and Disease

edited by

Györgyi Műzes

and

Ferenc Sipos

submission deadline 30 Apr 2025 | Viewed by 145 | Submission Open

Keywords: programmed cell death; apoptosis; pyroptosis; necroptosis; autophagy; ferroptosis; cuproptosis; immune system; autoimmune disease; immune-mediated diseases

(This special issue belongs to the Section Molecular Immunology)

Medicinal Mechanisms of Biologically Active Compounds in Cancer

edited by

Karthik Gourishetti

submission deadline 30 Apr 2025 | Viewed by 137 | Submission Open

Keywords: biologically active compounds; cancer treatment; apoptosis; tumor growth; natural products; oxidative stress

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Precision Medicine in Cancers

edited by

Mehdi Kardoust Parizi

submission deadline 30 Apr 2025 | Viewed by 132 | Submission Open

Keywords: precision medicine; cancer biomarkers; targeted therapy; genomic profiling; personalized treatment; tumor heterogeneity; molecular diagnostics; clinical research

(This special issue belongs to the Section Molecular Oncology)

Molecular Biology of Soybean

edited by Zhengjun Xia

submission deadline 30 Apr 2025 | Viewed by 132 | Submission Open

Keywords: soybean; growth and development; disease resistance; nodulation; nolecular mechanism; plant interaction

(This special issue belongs to the Section Molecular Plant Sciences)

Advanced Molecular Research in Polymers and Organic Semiconductors

edited by Ovidio Amado Almanza

submission deadline 30 Apr 2025 | Viewed by 131 | Submission Open

Keywords: polymer; organic semiconductors; molecular design; molecular interactions; thermal properties; optical properties; biointerfaces; sustainable materials

(This special issue belongs to the Section Materials Science)

Molecular Links Between Pregnancy and Chronic Diseases

edited by Marzena Helena Olesińska

submission deadline 30 Apr 2025 | Viewed by 126 | Submission Open

Keywords: pregnancy; chronic diseases; pregnancy complications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Reproductive Physiology and miRNA-Mediated Gene Regulation in Domestic Animals

edited by

Margherita Maranesi

and

Gabriella Guelfi

submission deadline 30 Apr 2025 | Viewed by 124 | Submission Open

Keywords: reproductive physiology; microRNAs; miRNAs; gene regulation; domestic animals

(This special issue belongs to the Section Molecular Biology)

Bile Acids and Bile Acid Modifications in Health and Disease

edited by

Francisco J. Osuna-Prieto

submission deadline 30 Apr 2025 | Viewed by 124 | Submission Open

Keywords: bile acids; bile acid modifications; bile acid signaling; bile acid metabolism; metabolic disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antioxidant and Antibacterial Properties of Phytochemicals

edited by Dalia Urbonaviciene and Vytaute Starkute

submission deadline 30 Apr 2025 | Viewed by 124 | Submission Open

Keywords: phytochemicals; natural preservatives; antioxidants; antibacterial properties; food; cosmetics; pharmaceuticals; animal feed

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Tumor Angiogenesis and Metastasis: From Molecular Signalling to Therapeutic Approaches

edited by

Federica Finetti

and

Lorenza Trabalzini

submission deadline 30 Apr 2025 | Viewed by 119 | Submission Open

Keywords: tumour angiogenesis; tumour invasion; tumour metastasis; molecular mechanisms; metabolic patterns; signalling pathways

(This special issue belongs to the Section Molecular Oncology)

Redox Homeostasis and Oxidative Stress in Human Metabolism and Disease：2nd Edition

edited by

Alina Woźniak

and

Jaroslaw Nuszkiewicz

submission deadline 30 Apr 2025 | Viewed by 118 | Submission Open

Keywords: antioxidants; biomarkers; cellular functions; disease etiology; disease progression; metabolic disorders; metabolic signaling; oxidative stress; pathophysiological states; reactive oxygen species; redox homeostasis; redox signaling

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Recent Advances in Protein Folding and Misfolding

edited by

Ho-Jin Lee

submission deadline 30 Apr 2025 | Viewed by 113 | Submission Open

Keywords: protein folding; protein misfolding; 3D protein structure; CRISPR/Cas 9

(This special issue belongs to the Section Molecular Biophysics)

Cutting-Edge Research on Nanosensors and Microsensors

edited by Beata Paczosa-Bator

submission deadline 30 Apr 2025 | Viewed by 111 | Submission Open

Keywords: nanosensors and microsensors; innovations; nanomaterials; nanotechnology; biomedical devices; point-of-care and point-of-use testing; environmental control

(This special issue belongs to the Section Materials Science)

Environmental Stress and Metabolic Responses in Plants

edited by

Tibor Janda

submission deadline 30 Apr 2025 | Viewed by 111 | Submission Open

Keywords: abiotic stress; acclimation; biotic stress; climate change; light stresses; oxidative stress; photoinhibition; redox regulation; signalling; stress alleviation; stress detection in plants

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Perspectives in Lung Diseases: Pathogenesis, Diagnosis, and Treatment

edited by

Elena Levantini

submission deadline 30 Apr 2025 | Viewed by 110 | Submission Open

Keywords: lung cancer models; cancer stem cells; tumor microenvironment; targeted therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 2901-2950 on page 59 of 76.

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