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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Research on Nucleic Acids: Therapeutic Potential and Applications, 2nd Edition

edited by

Veronica Esposito

and

Antonella Virgilio

submission deadline 20 Feb 2025 | 3 articles | Viewed by 2185 | Submission Open

Keywords: aptamer; decoy; DNAzyme; ribozyme; siRNA; miRNA; antisense oligonucleotide; antigene strategy; G-quadruplex; triplex

(This special issue belongs to the Section Biochemistry)

Molecular Insights into Macromolecules Structure, Function, and Regulation: 2nd Edition

edited by

Zhiwei Yang

submission deadline 20 Feb 2025 | 2 articles | Viewed by 2112 | Submission Open

Keywords: conformational dynamics; structural modeling; docking; molecular recognition; regulation mechanism; rational design; molecular dynamic simulation

(This special issue belongs to the Section Molecular Biophysics)

Animal Gut Microbial Metagenome

edited by

Shengguo Zhao

submission deadline 20 Feb 2025 | 1 articles | Viewed by 2001 | Submission Open

(This special issue belongs to the Section Molecular Microbiology)

Immunotherapy in Tumors: Treatments, Complications and Diagnostic Evaluation of Response

edited by

Fabio Sandomenico

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1932 | Submission Open

Keywords: cancer immunotherapy; immune checkpoint inhibitor; complications; potential side-effects; immune response

(This special issue belongs to the Section Molecular Oncology)

Long History of Snake Toxins: The 60th Anniversary of the α-Bungarotoxin Discovery

edited by

Yuri N. Utkin

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1893 | Submission Open

Keywords: animal venoms; toxins; discovery; structure; biological activity

(This special issue belongs to the Section Molecular Toxicology)

Rhizobium-Plant Interaction

edited by

Alessio Mengoni

and

Camilla Fagorzi

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1880 | Submission Open

Keywords: nitrogen-fixation; bioinoculation; plant microbiome; rhizobia; plant symbionts; sustainable agriculture; rhizosphere ecology

(This special issue belongs to the Section Molecular Microbiology)

Insights into Redox Homeostasis and Oxidative Stress

edited by

Dimitrios Kouretas

, Zoi Vasiliki Skaperda and

Fotios Tekow

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1844 | Submission Open

Keywords: oxidative stress; redox homeostasis; redox signaling; reactive oxygen species; oxidative damage; diseases

(This special issue belongs to the Section Molecular Pharmacology)

Elective Affinities

edited by

Călin Gabriel Floare

and Elena Matei

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1833 | Submission Open

Keywords: re-entrant and liquid-liquid phase transitions; protein-ligand and protein-protein interactions; protein folding; misfolding and aggregation; chaperones; spectroscopy methods; structure-function relationship; conformational transitions; allostery; molecular recognition; molecular docking and molecular dynamics simulations

(This special issue belongs to the Section Molecular Biology)

Bioactive Compounds of Natural Origin

edited by

Katarzyna Pacyga

and

Anna Duda-Madej

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1831 | Submission Open

Keywords: plants; extraction methods; bioactive compounds; natural products; application

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Calcium Metabolism and Regulation

edited by Hermann Salmhofer and

Michael Lichtenauer

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1824 | Submission Open

Keywords: pathologic calcification; calcification inhibitors; calciprotein particles; Runx-2; apatite; matrix Gla protein; fetuin-A; vitamin D; parathyroid hormone

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Natural Products: New Insights into Overcoming Oxidative Stress in Pathological Diseases

edited by

Maria G. Bottone

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1812 | Submission Open

Keywords: natural products; nutraceuticals; oxidative stress; antioxidants; ROS; redox signaling; oxidative stress; pathological diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

An Update for Photodynamic Therapy as a Versatile Tool for Biological Breakthroughs

edited by

Leandro M. O. Lourenço

João P. C. Tomé

and

Augusto C. Tomé

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1811 | Submission Open

Keywords: photodynamic theraphy (aPDT); photochemistry; dyes; photosensitizers; porphyrins; phthalocyanines; and other derivatives; reactive oxygen species (ROS); singlet oxygen; cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gut Microbiota and Metabolic Diseases 2.0

edited by

William K.K. Wu

and

Sunny H. Wong

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1786 | Submission Open

Keywords: metabolic syndromes; obesity; diabetes mellitus; microbiome; dyslipidemia; adiposity; insulin resistance; fatty liver disease

(This special issue belongs to the Section Molecular Microbiology)

Editorial Board Members’ Collection Series: Human Traits and Genomics

edited by

Giovanni Malerba

Lidia Larizza

and

Salvatore Saccone

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1778 | Submission Open

Keywords: genetic data analysis; genomic profiling; trait inheritance; DNA and RNA sequencing approaches; deep learning methods

(This special issue belongs to the Section Molecular Genetics and Genomics)

Toxicity of Heavy Metal Compounds

edited by

Astrid Barkleit

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1753 | Submission Open

Keywords: heavy metal; coordination; complexation; binding form; speciation; biomolecules; (cyto-) toxicity; cell death mechanism; spectroscopy; microscopy

(This special issue belongs to the Section Molecular Toxicology)

The Roles of Photodynamic Therapy in Tumors and Cancers

edited by Jianyong Liu

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1750 | Submission Open

Keywords: photodynamic therapy; PDT; photodetection; photosensitizers; photosensitizing agents; reactive oxygen species; molecular mechanisms; cell necrosis; apoptosis; singlet oxygen; synergetic therapy; combination therapy; delivery vehicles; immunophototherapy; nano-photosensitizer

(This special issue belongs to the Section Molecular Oncology)

Dysfunctional Neural Circuits and Impairments in Brain Function

edited by

Takashi Tominaga

and

Ichiro Takashima

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1738 | Submission Open

Keywords: neural circuits; dysfunctional circuits; neuropsychiatric disorders; optical recording; voltage-sensitive dyes; genetically encoded optical indicators; local brain activity; whole brain activity; cognitive impairments; behavioral test

(This special issue belongs to the Section Molecular Neurobiology)

Micro/Nanofluidics: Novel Bioanalytical Technology

edited by

Zongjie Wang

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1712 | Submission Open

Keywords: microfluidics; nanofluidics; analytical chemistry; material chemistry; biosensor; chemsensor; diagnostics

(This special issue belongs to the Section Biochemistry)

Current Advances in Diagnostic and Therapeutic Approaches for Gastric Cancer

edited by

Diana Noronha Nunes

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1705 | Submission Open

Keywords: gastric cancer; non-invasive diagnostic methodologies; biomarkers; artificial intelligence; digital pathology; response to treatment

(This special issue belongs to the Section Molecular Oncology)

Molecular Biology of Protein Kinases: Regulatory Mechanisms, Therapeutic Targets and Cancer Treatments

edited by Jaw Ji Yang

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1684 | Submission Open

Keywords: protein kinases; signal transduction; cancer therapy; regulatory mechanisms; kinase inhibitors; therapeutic targets; molecular biology; structural biology; translational research; clinical applications

(This special issue belongs to the Section Molecular Biology)

Molecular Insight into Zoonotic Infections

edited by Marine Combe

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1672 | Submission Open

Keywords: zoonoses; zoonotic pathogens; neglected zoonotic diseases; molecular assays; genetic diversity; PCR; qPCR; ddPCR; sequencing; NGS

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Concepts, New Perspectives, and Current Therapies for Parkinson’s Disease: 2nd Edition

edited by

Malgorzata Zaremba

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1626 | Submission Open

Keywords: Parkinson’ s disease; therapy; drug; repurposing; novel compound; neurodegeneration; neuroinflammation

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Molecular Mechanisms of Neurodegenerative Diseases

edited by Aslihan Ugun-Klusek

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1544 | Submission Open

Keywords: neurodegeneration; Parkinson’ s disease; Alzheimer’ s disease; molecular signalling; neuronal death

(This special issue belongs to the Section Molecular Neurobiology)

Properties, Biosynthesis and Application of Antimicrobial Compounds

edited by

Inna P. Solyanikova

and

Tatiana Abashina

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1536 | Submission Open

Keywords: antimicrobial compounds of microorganisms; whole genome sequencing; secondary metabolites; antimicrobial activity; biosynthesis; application

(This special issue belongs to the Section Molecular Microbiology)

Endothelial Dysfunction: Molecular Mechanisms and Therapeutic Strategies

edited by

Nunzia D’Onofrio

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1505 | Submission Open

Keywords: endothelial dysfunction; inflammation; mitochondria; redox homeostasis; metabolic impairment; epigenetic; sirtuin; microRNA; senescence

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Trends in Biologically Active Compounds in Age-Related Diseases

edited by Celia Andrés Juan

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1494 | Submission Open

Keywords: age-related diseases; oxidative stress and inflammation; energy failure; mitochondrial dysfunction; deregulated autophagy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Cardiovascular Diseases: Aging and Other Risk Factors

edited by

Silvia Liskova

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1467 | Submission Open

Keywords: aging; hypertension; endothelium; vascular smooth muscle cells; pulmonary hypertension; atherosclerosis; hyperlipidemia

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Inflammasomes in Human Disease

edited by Marisol Fernández-Ortiz

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1450 | Submission Open

Keywords: inflammasome; IL-1 cytokines; inflammatory caspases; inflammasome activity manipulation

(This special issue belongs to the Section Molecular Immunology)

Molecular and Neuromuscular Mechanisms in Skeletal Muscle Aging

edited by

Rosa Mancinelli

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1427 | Submission Open

Keywords: aging; sarcopenia; neuromuscular junction; molecular muscle modifications; myokines

(This special issue belongs to the Section Molecular Biology)

Brain Tumors: From Biomarkers to Novel Therapies

edited by

Okay Saydam

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1414 | Submission Open

Keywords: glioblastoma; medulloblastoma; meningioma; brain tumors; exosomes; circulating tumor markers; drug development and delivery technologies; molecular biology

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances and Insights into Liver Diseases

edited by

Jacek Baj

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1407 | Submission Open

Keywords: liver; hepatocellular carcinoma; cancer; hepatitis; cirrhosis; encephalopathy; non-alcoholic fatty liver disease; autoimmune diseases; Wilson’ s disease; fatty liver disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Targeted Radioligand Therapy and Immunotherapy for Cancer Treatment

edited by

Jinda Fan

and

Carolina de Aguiar Ferreira

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1401 | Submission Open

Keywords: targeted radioligand therapy; immunotherapy; receptor targeting; tumor-specific antigens; immune checkpoint inhibitors; radiosensitization; tumor microenvironment; combination therapy

(This special issue belongs to the Section Molecular Oncology)

New Insights into Immune and Anti-inflammatory Strategies for Improving Human Health

edited by

Nikolina Mihaylova

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1351 | Submission Open

Keywords: inflammation; immunotherapy; autoimmune disease; cancer; immune activation; modulation; tolerance

(This special issue belongs to the Section Molecular Immunology)

Recombinant Proteins, Protein Folding and Drug Discovery

edited by

Mohamed Raafat El-Gewely

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1290 | Submission Open

Keywords: heterologous hosts for gene expression; recombinant therapeutic proteins; antigens; and antibodies; large scale production of recombinant proteins; recombinant protein bioreactor; downstream processing of recombinant proteins; codon optimization for protein expression; refolding of misfolded recombinant proteins; solubilization of aggregated and inclusion bodies of recombinant proteins; protein target validation for drug discovery and development; protein target expression for drug discovery and development; metabolic engineering of recombinant protein production; regulatory noncoding RNAs to boost the expression of protein; the use of foldases & conformases in recombinant protein expression; delivery of therapeutic proteins; therapeutic protein Vs mRNA therapeutics

(This special issue belongs to the Section Biochemistry)

Thermophilic, Heterotrophic Anaerobes—Recent Advances in Phylogeny and Biotechnology

edited by

Johann Örlygsson

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1275 | Submission Open

Keywords: thermophilic; anaerobe; genetic engineering; biofuels; fine chemicals; enzymes

(This special issue belongs to the Section Molecular Microbiology)

Molecular Advances in Proteins and Photosynthesis Dynamics

edited by Ilya B. Kovalenko

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1271 | Submission Open

Keywords: photosynthesis; electron transport; molecular dynamics; proteins; protein-protein interaction; conformational changes; reaction center; mobile electron carrier

(This special issue belongs to the Section Biochemistry)

Microbial Enzymes for Biotechnological Applications 2.0

edited by

Salvatore Fusco

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1244 | Submission Open

Keywords: microbial enzymes; whole-cell biocatalysts; extremozyme; enzyme assays; protein engineering

(This special issue belongs to the Section Biochemistry)

The Interplay of Oxidative Stress and Inflammation: From Mechanisms to Therapeutic Approaches 2.0

edited by

Lorenza Speranza

and

Sara Franceschelli

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1229 | Submission Open

(This special issue belongs to the Section Biochemistry)

Molecular Mechanisms of Tendinopathy: Unraveling the Pathogenesis of Tendon Diseases

edited by

Pauline Po Yee Lui

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1218 | Submission Open

Keywords: tendinopathy; tendon pain; stiffness; physical disability; etiopathogenesis; molecular mechanisms; tendon reattachment; tendon repair; advanced molecular tools; omics techniques; biophysical therapies; novel biomaterials

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Anti-bacterial Polymers

edited by Rosie Yagmur Yegin

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1217 | Submission Open

Keywords: anti-bacterial polymers; polymer synthesis; biological evaluation; mechanistic studies; application of biocide polymers; food packaging; biocide polymers coatings and surfaces; antibiofilm; foodborne pathogens; smart delivery systems

(This special issue belongs to the Section Macromolecules)

Molecular Insight into Oxidative Stress in Plants

edited by

Agnieszka Hanaka

and

Sylwia Zielińska

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1215 | Submission Open

Keywords: ROS detoxification pathways; enzymatic and non-enzymatic antioxidants; SOS markers at the molecular level; cross-talk of ROS with phytohormones; restoration of plant cell homeostasis; mechanisms of oxidative damages and antioxidant protection; multiple signaling cascades in SOS prevention; transcriptomic analysis in gene regulatory networks; metabolomic and proteomic analyses

(This special issue belongs to the Section Molecular Plant Sciences)

Anxiolytic or Antidepressant Activity from Active Principles in Medicinal Plants

edited by Carolina López-Rubalcava and Erika Estrada Camarena

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1173 | Submission Open

Keywords: phytopharmacology; anxiety; depression; medicinal plants; animal models

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Immunology and Inflammation during and after Infectious Diseases

edited by

Manuela Ceccarelli

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1165 | Submission Open

Keywords: bacterial infections; fungi infections; HIV; COVID-19; immune response; inflammation

(This special issue belongs to the Section Molecular Immunology)

The Role of Heat Shock Proteins: From Molecular Mechanisms to Therapeutics 2.0

edited by

Gregory Blatch

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1113 | Submission Open

Keywords: heat shock proteins; molecular chaperones; co-chaperones; protein folding; chronic diseases; infectious diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Modern Plant Cell Biotechnology: From Genes to Structure, 2nd Edition

edited by

Ewa Kurczyńska

and

Alexander Betekhtin

submission deadline 20 Feb 2025 | 2 articles | Viewed by 1088 | Submission Open

Keywords: genetic engineering techniques; gene modification; gene editing; regulation of gene expression; plant cell biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Bone Tissue Engineering: Opportunities and Challenges

edited by

Elisa Mazzoni

and

Maria Rosa Iaquinta

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1038 | Submission Open

Keywords: material; biocompatibility; scaffold; regeneration; bone; osteoinductivity; tissue; stem cells; microenvironment processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ligament/Tendon and Cartilage Tissue Engineering and Reconstruction

edited by

Gundula Schulze-Tanzil

submission deadline 20 Feb 2025 | 1 articles | Viewed by 1028 | Submission Open

Keywords: cartilage; tendon; ligament; anterior cruciate ligament; bioprinting; scaffold; bioreactor; tissue engineering

(This special issue belongs to the Section Materials Science)

Recent Advances in Discovery of Microbial and Plant Specialized Metabolites

edited by

Marco Masi

submission deadline 20 Feb 2025 | 1 articles | Viewed by 944 | Submission Open

Keywords: natural products; specialized metabolites; secondary metabolites; plant; pharmacology

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Natural Products in Lifestyle-Related Diseases: Molecular Mechanisms, Prevention and Treatments

edited by

Takanobu Takata

submission deadline 20 Feb 2025 | 1 articles | Viewed by 936 | Submission Open

Keywords: natural products; crude drugs; lifestyle-related diseases; diabetes mellitus; cardiovascular disease; non-alcoholic hepatosteatosis; cancer; sarcopenia; Alzheimer’ s disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

CDKL5 Deficiency Disorders: From Molecular Mechanisms to Therapeutics

edited by

Isabella Barbiero

and Charlotte Kilstrup-Nielsen

submission deadline 20 Feb 2025 | 1 articles | Viewed by 923 | Submission Open

Keywords: CDKL5; pathophysiology; therapeutic strategies; in vitro and in vivo studies; neurobiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 2951-3000 on page 60 of 68.

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