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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular and Electrochemical Mechanisms of Metal Corrosion
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 791 | Submission Open
Keywords: metal corrosion; molecular mechanisms; electrochemistry; surface chemistry; corrosion inhibitors; passivation
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Decoding the Microbial Influence on Host Gene Expression submission deadline 20 Aug 2026 | 1 articles | Viewed by 762 | Submission Open
Keywords: microbiota; host; gene expression; in silico; bioinformatics; in vitro; in vivo
(This special issue belongs to the Section Molecular Microbiology)
Artificial Intelligence Advancing Computer-Aided Drug Discovery
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 691 | Submission Open
Keywords: machine learning; deep learning; computer-aided drug design; target identification; AI-assisted molecular diagnosis; AI-driven pharmacokinetic profiling; virtual screening; network pharmacology; drug repurposing; molecular dynamics simulation; computational chemistry; AI in nanotechnology
(This special issue belongs to the Section Molecular Informatics)
Carbon Fiber, Carbon Nanofiber for Composites: Synthesis, Processing, Molecular Structure, Characterization, and Application
edited by Tridung Ngo
submission deadline 20 Aug 2026 | Viewed by 678 | Submission Open
Keywords: carbon fiber; carbon nanofiber; nanotube; carbon fiber composites; synthesis; advanced manufacturing; characterization; recent advancements; applications
(This special issue belongs to the Section Materials Science)
Autoimmune Diseases: From Molecular Mechanisms to Therapeutic Innovations submission deadline 20 Aug 2026 | 1 articles | Viewed by 661 | Submission Open
Keywords: autoimmunity; biological biomarkers; personalized therapies; biologics and JAK inhibitors; CAR-T cell therapy
(This special issue belongs to the Section Molecular Immunology)
Research Progress of Fluorescent Proteins in Molecular Biology
edited by Matteo Grenzi
submission deadline 20 Aug 2026 | 1 articles | Viewed by 635 | Submission Open
Keywords: fluorescence microscopy; fluorescence live-cell imaging; quantitative imaging; fluorescent biosensors; in vivo imaging; innovative fluorescence microscopy techniques
(This special issue belongs to the Section Molecular Biology)
Structure, Properties, and Applications of Carbon Materials submission deadline 20 Aug 2026 | 1 articles | Viewed by 634 | Submission Open
Keywords: carbon-based structures; diamonds; carbon quantum dots; carbon composites; graphene; nanotubes
(This special issue belongs to the Section Materials Science)
Synthesis and Structural Studies of Potential Anticancer Drugs
edited by Janusz Madaj
submission deadline 20 Aug 2026 | 1 articles | Viewed by 631 | Submission Open
Keywords: medicinal chemistry; drug discovery; design and synthesis of bioactive compounds; molecular modeling; X-ray crystallography; structure– activity relationships; structure-based drug design
(This special issue belongs to the Section Molecular Pharmacology)
Breakthroughs in Anti-Cancer Agents Discovery
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 588 | Submission Open
Keywords: medicinal chemistry; drug discovery; cancer; anti-cancer agents; synthesis; bioactive molecules; biological evaluation; computational drug discovery; artificial intelligence
(This special issue belongs to the Section Molecular Oncology)
Kidney Disease: Molecular Insights and Emerging Therapies
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 582 | Submission Open
Keywords: kidney disease; molecular mechanism; precision medicine; translational nephrology; targeted molecular therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Developing Methods and Molecular Basis in Plant Biotechnology: 2nd Edition
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 530 | Submission Open
Keywords: plant biotechnology; plant genetics; plant proteomics; plant metabolomics; stress
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Mechanisms of Thromboinflammation
edited by Ana B. Arroyo
submission deadline 20 Aug 2026 | Viewed by 520 | Submission Open
Keywords: thromboinflammation; coagulation; inflammation; immune system; sepsis; stroke; autoimmune diseases; cancer; hematology; biomarkers; translational medicine
(This special issue belongs to the Section Molecular Immunology)
Systemic Lupus: Molecular Research, New Biomarkers and Novel Therapy
edited by Juan Pablo Mackern-Oberti
submission deadline 20 Aug 2026 | 1 articles | Viewed by 505 | Submission Open
Keywords: lupus; biomarkers; autoimmunity; inflammation; therapy; treatment; endocrine; prolactin; stress; T cell and B cell activation; T cell and B cell proliferation; antigenic immunosuppression
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Plant Responses to Abiotic Stress: Mechanisms and Adaptations submission deadline 20 Aug 2026 | Viewed by 501 | Submission Open
Keywords: salinity stress; heat and cold stress; oxidative stress; signal transduction; stress-responsive genes; antioxidant defence mechanisms; hormonal regulation; molecular adaptation; epigenetic regulation; plant-microbe interaction; crop improvement; stress-resilient plants
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Insights in Food Science: From Nutritional Value to Safety Evaluation
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 501 | Submission Open
Keywords: nutraceutical; food safety; analytical methods; novel foods; food analysis
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Bioinformatics Analysis of Single Cell and Spatial Multi-Omics
edited by Fahong Yu
submission deadline 20 Aug 2026 | Viewed by 487 | Submission Open
Keywords: bioinformatics; single-cell omics; spatial multi-omics; matabolomics; genomics; transcriptomics; proteomics; next-generation sequencing techniques
(This special issue belongs to the Section Molecular Informatics)
Roles and Mechanisms of Non-Coding RNAs in Breast Cancer
edited by
submission deadline 20 Aug 2026 | Viewed by 465 | Submission Open
Keywords: breast cancer; NcRNA; MmiRNA; LncRNA; CircRNA; PiRNA; exosome-packed ncRNA; role and mechanisms of ncRNA in breast cancer tissue or cell lines; modulation of ncRNA levels by knock-out or knock-down approaches; effects on breast cancer cell proliferation; invasion; or apoptosis; identification of BC-relevant ncRNA– mRNA networks; targeting ncRNAs with potential clinical implications
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cognitive Aging: Molecular Perspectives
edited by
submission deadline 20 Aug 2026 | Viewed by 462 | Submission Open
Keywords: brain; neuron; aging; neurodegeneration; cognitive neuroscience; inflammation; regeneration; behavioral neuroscience; pharmacology; brain disorders
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Natural Products in Cancer Prevention and Treatment—Second Edition submission deadline 20 Aug 2026 | 2 articles | Viewed by 456 | Submission Open
Keywords: natural products; cancer; therapeutic strategies; novel molecular pathways
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Aspects of Diabetes and Its Complications
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 450 | Submission Open
Keywords: obesity; insulin resistance; type 2 diabetes; atherosclerosis; endothelial dysfunction; cardiovascular disease; peripheral artery disease; diabetic feet; diabetic micoangiopathy; diabetic neuropathy; regenerative medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Diet in Lipid and Lipoprotein Metabolism
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 431 | Submission Open
Keywords: dyslipidemia; hypertension; diabetes; dementia
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Electromagnetic Field Interactions with Biomolecules
edited by Samina Masood
submission deadline 20 Aug 2026 | Viewed by 430 | Submission Open
Keywords: magnetic field; biomolecules; medicine; drug delivery; protective methods; disease control
(This special issue belongs to the Section Biochemistry)
Tumor Specific Immunotherapeutic Targets
edited by
submission deadline 20 Aug 2026 | Viewed by 420 | Submission Open
Keywords: immunotherapy; immunotherapeutics; tumour-specific antigens; immunotherapeutic targets; multi-omics approaches
(This special issue belongs to the Section Molecular Immunology)
Advances in Plant Cell Dynamics
edited by
submission deadline 20 Aug 2026 | Viewed by 403 | Submission Open
Keywords: organelles; cellular polarity; cytoskeleton; vesicle trafficking; cell wall synthesis; signalling; differentiation
(This special issue belongs to the Section Molecular Plant Sciences)
Fractalkine (CX3CL1) and Its Chemoattractant and Adhesion Molecule Properties in Health and Disease, 2nd Edition
edited by Dariusz Szukiewicz
submission deadline 20 Aug 2026 | 1 articles | Viewed by 397 | Submission Open
Keywords: fractalkine; transmembrane fractalkine; soluble fractalkine; fractalkine receptor; CX3CL1-CX3CR1 signaling; inflammation; chemokine; cell adhesion; chemotaxis; immune response; angiogenesis; implantation; atherosclerosis; carcinogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular and Cellular Targets on Anticancer Research and Perspectives submission deadline 20 Aug 2026 | Viewed by 387 | Submission Open
Keywords: anticancer; molecular targets; targeted cancer therapies; malignancy
(This special issue belongs to the Section Molecular Oncology)
New Insight into Bacteriophage and Their Potential Applications
edited by Wilfried Moreira
submission deadline 20 Aug 2026 | Viewed by 381 | Submission Open
Keywords: bacteriophage; phage biology; phage-host interactions; antimicrobial resistance
(This special issue belongs to the Section Molecular Microbiology)
RNA Biology: Unraveling the Complex Interplay Between Proteins and RNAs in Gene Expression and Regulation, 2nd Edition
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 380 | Submission Open
Keywords: RNA biology; protein– RNA interplay; gene expression; post-transcriptional modifications; non-coding RNAs
(This special issue belongs to the Section Molecular Genetics and Genomics)
New Optical, Electrical, and Thermal Materials: Recent Advances and Challenges
edited by Luyi Zou
submission deadline 20 Aug 2026 | Viewed by 343 | Submission Open
Keywords: optical materials; electrical materials; thermal materials; molecular structure; molecular composition; structural performance
(This special issue belongs to the Section Materials Science)
Novel Heterocyclic Bioactive Compounds: Design, Synthesis and Biological Evaluation
edited by
submission deadline 20 Aug 2026 | Viewed by 334 | Submission Open
Keywords: heterocyclic compounds; drug design; medicinal chemistry; bioactive molecules; structure– activity relationships; synthetic methodologies; molecular mechanisms of action; pharmacological evaluation; therapeutic agents
(This special issue belongs to the Section Biochemistry)
Photosensitizers for Photodynamic Therapy: From Molecular Design to Application submission deadline 20 Aug 2026 | Viewed by 327 | Submission Open
Keywords: photodynamic therapy (PDT); photosensitizers (PS); reactive oxygen species (ROS); molecular design; nanocarriers; porphyrins and analogs; targeted drug delivery; translational medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Synthetic Lethality Strikes: Outsmarting Cancer with Precision Medicine
edited by
submission deadline 20 Aug 2026 | Viewed by 311 | Submission Open
Keywords: synthetic lethality; precision medicine; DDR modulators; non-DDR modulators; cancer; BRCA; PARP; RAD51; RAD52
(This special issue belongs to the Section Molecular Oncology)
Molecular Insights into Microbial Adaptations to Marine Plastics
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 303 | Submission Open
Keywords: plastisphere; marine plastic debris; microbial colonization; biofilms; microbial adaptation; community assembly; quorum sesing; plastic biodegradation; biogeochemical cycling; antibiotic resistance genes; marine microbial ecology; metagenomics; microbe– plastic interactions; microbial succession
(This special issue belongs to the Section Molecular Microbiology)
Coordination Chemistry: From Fundamental Principles to Multifunctional Applications
edited by
submission deadline 20 Aug 2026 | Viewed by 299 | Submission Open
Keywords: coordination compounds; metal– ligand interactions; ligand design and synthesis; spectroscopic characterization; coordination geometry; molecular architecture; ion-association complexes; supramolecular chemistry; catalysis and activation mechanisms; functional materials; metal– organic frameworks; magnetism in coordination compounds; redox-active complexes; environmental and green chemistry applications; sensors and molecular devices; bioinorganic chemistry; medicinal coordination chemistry; theoretical and computational coordination chemistry
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Advanced Strategies in Bacterial Antibiotic Resistance
edited by Xuemei Yang
submission deadline 20 Aug 2026 | 1 articles | Viewed by 297 | Submission Open
Keywords: antibiotic resistance; resistance mechanisms; antibiotic resistance genes (ARGs); antibiotic tolerance; heteroresistance; horizontal gene transfer (HGT); compensatory evolution
(This special issue belongs to the Section Molecular Microbiology)
From Mechanisms to Medicine: Cellular Insights into Pulmonary Hypertension
edited by
submission deadline 20 Aug 2026 | Viewed by 294 | Submission Open
Keywords: vascular remodeling; cellular mechanisms; hypoxia; growth factors; inflammation
(This special issue belongs to the Section Molecular Biology)
Recent Advances in Brain Tumor Research and Treatment submission deadline 20 Aug 2026 | Viewed by 289 | Submission Open
Keywords: brain tumor; gliomas; brain metastases; translational research; molecular biology
(This special issue belongs to the Section Molecular Oncology)
Stem Cell and Epigenetic Regulation in Regenerative Medicine
edited by
submission deadline 20 Aug 2026 | Viewed by 288 | Submission Open
Keywords: mesenchymal stem cells; regenerative medicine; stemness genes; stem cell differentiation; molecular regulation; gene expression; cell– environment interactions; conditioned medium; secreted factors; epigenetic modification
(This special issue belongs to the Section Molecular Biology)
Advances in Dendritic Cell-Based Immunotherapy of Cancer
edited by Helena Haque Chowdhury and Matjaz Jeras
submission deadline 20 Aug 2026 | Viewed by 282 | Submission Open
Keywords: DC-based immunotherapy of cancer; immunostimulatory dendritic cell (DC) generation; dosage and routes of DC administration; body distribution of DCs post-application; frequency and duration of DC applications; tumour immunosuppressive mechanisms’ modulation; combinatorial DC-based anticancer immunotherapy
(This special issue belongs to the Section Molecular Immunology)
Early Diagnosis and Advanced Therapies of Genetic Disorders
edited by
submission deadline 20 Aug 2026 | Viewed by 282 | Submission Open
Keywords: genetic disorders; rare diseases; disease diagnostics; therapeutic targets; gene variants
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Roots, Transporters, and Signals: Molecular Insights into Plant Mineral Nutrition and Heavy Metals Stress
edited by
submission deadline 20 Aug 2026 | Viewed by 275 | Submission Open
Keywords: plant mineral nutrition; heavy metals; toxic element; transporter; signaling pathway
(This special issue belongs to the Section Molecular Plant Sciences)
Plant Epigenetic Memory Under Abiotic Stress
edited by
submission deadline 20 Aug 2026 | Viewed by 274 | Submission Open
Keywords: plant epigenetics; epigenetic memory; abiotic stress; DNA methylation; histone modification; chromatin remodeling; transgenerational inheritance; stress-responsive genes
(This special issue belongs to the Section Molecular Plant Sciences)
Peripheral Neuropathy: Exploring Pathogenic Pathways and Therapeutic Approaches
edited by Yuehling Hsieh
submission deadline 20 Aug 2026 | Viewed by 268 | Submission Open
Keywords: peripheral neuropathy; biochemical mechanisms; biomarkers; nerve regeneration; therapeutic approaches; pain management; denervated muscle atrophy; translational medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Allergen Immunotherapy: Current Concepts and Future Directions submission deadline 20 Aug 2026 | Viewed by 263 | Submission Open
Keywords: allergen immunotherapy; oral immunotherapy; Hymenoptera venom; allergy extracts; adjuvants
(This special issue belongs to the Section Molecular Immunology)
Recent Advances in Molecular Imaging and Therapy
edited by
submission deadline 20 Aug 2026 | Viewed by 259 | Submission Open
Keywords: molecular imaging; therapy; clinical translation; precision medicine; radiotheranostics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Biomaterials: Molecular Design and Applications
edited by
submission deadline 20 Aug 2026 | Viewed by 253 | Submission Open
Keywords: biomaterials; molecular design; biomedical applications
(This special issue belongs to the Section Materials Science)
The Role of Ion Channels in Health and Disease
edited by
submission deadline 20 Aug 2026 | Viewed by 249 | Submission Open
Keywords: ion channel; molecular mechanisms; channelopathies; drug discovery; electrophysiology
(This special issue belongs to the Section Molecular Biology)
Research on the Key Role of Ubiquitination in Signaling and Cancer
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 247 | Submission Open
Keywords: ubiquitin; ubiquitination; E3 ligase; deubiquitinating enzymes; protein degradation; mutations; cancer progression; signal transduction; drug development
(This special issue belongs to the Section Molecular Oncology)
Cellular Physiology and Aging: Membrane Dynamics, Intracellular Environment and Signaling Pathways
edited by , and Sara Spinelli
submission deadline 20 Aug 2026 | Viewed by 229 | Submission Open
Keywords: aging; oxidative stress; ion channels; antioxidant molecules; membrane transport systems; redox signaling; cellular senescence; inflammation; intracellular signaling pathways; mitochondrial dysfunction; bioactive compounds; cell physiology; homeostasis; longevity; age-related diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Protein-Targeted Therapeutics: Functional Modulation in Disease Pathways submission deadline 20 Aug 2026 | Viewed by 228 | Submission Open
Keywords: protein-targeted therapeutics; proteins inhibitors; ligand binding; conformational changes
(This special issue belongs to the Section Biochemistry)
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