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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research in Rheumatoid Arthritis
edited by Ângelo Calado
submission deadline 20 Mar 2025 | 1 articles | Viewed by 1022 | Submission Open
Keywords: rheumatoid arthritis; synovium; autoimmunity; rheumatology; omics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms of Microbe–Skin Interactions
edited by
submission deadline 20 Mar 2025 | 1 articles | Viewed by 999 | Submission Open
Keywords: colonization; cosmetics; diseases (e.g.; acne; diabetic foot syndrome (DFS); psoriasis; etc.); health; immunity; lipidomics; metabolomics; metagenomics; neurotransmitter; physiology; skin habitat; skin microbiota; prebiotics; probiotics; wound healing
(This special issue belongs to the Section Molecular Microbiology)
Physiology and Molecular Medicine of Molecular Hydrogen
edited by and John Nagi Kheir
submission deadline 20 Mar 2025 | 1 articles | Viewed by 998 | Submission Open
Keywords: molecular hydrogen; reactive oxygen species; nitric oxide; inflammation; cardiovascular disease
(This special issue belongs to the Section Molecular Biology)
Mast Cells in Immunity and Disease: Second Edition submission deadline 20 Mar 2025 | 1 articles | Viewed by 998 | Submission Open
Keywords: mast-cell activation; secretion of MC-derived mediators; allergy; asthma; allergic rhinitis; urticaria; anaphylaxis; mastocytosis
(This special issue belongs to the Section Molecular Immunology)
Advances and Challenges of Molecular Research on Disease in Animal Models in Biomedicine
edited by Minolfa C. Prieto
submission deadline 20 Mar 2025 | 1 articles | Viewed by 996 | Submission Open
Keywords: animal models; cardiovascular disease; renal disease; metabolic; neurological; behavioral; and oncological disorders; pathophysiology; cell and molecular research
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Neurodegenerative Diseases Research and Therapy—Third Edition
edited by
submission deadline 20 Mar 2025 | 1 articles | Viewed by 990 | Submission Open
Keywords: neurodegenerative diseases; therapy; molecular mechanisms; neuron; astrocytes; microglia; inflammation; brain; drug delivery
(This special issue belongs to the Section Molecular Neurobiology)
Synthesis, Characterization and Application of Metal and Metal Oxide Nanomaterials submission deadline 20 Mar 2025 | 1 articles | Viewed by 988 | Submission Open
Keywords: metal nanoparticles; metal nanoclusters; properties of metal nanostructures; optical sensing and bio-sensing; pollutant sensing; metal oxide-based materials; photocatalysis; decomposition of pollutants by photocatalysis; energy production; conversion; and storage; water treatment
(This special issue belongs to the Section Materials Science)
Molecular Advances in Mental Health and Disorders
edited by Eva Christina Schulte
submission deadline 20 Mar 2025 | 1 articles | Viewed by 961 | Submission Open
Keywords: molecular studies; mental health disorders; model systems; molecular epidemiology; omics   TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified ChinesePRO Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Biochemistry, Molecular and Cell Biology Beyond Flowers
edited by
submission deadline 20 Mar 2025 | 1 articles | Viewed by 930 | Submission Open
Keywords: flowers; homeotic genes; MADSBox; molecular expression; pollination; stress; transcription factors
(This special issue belongs to the Section Molecular Plant Sciences)
Biomarkers and Early Detection Strategies of Ovarian Tumors
edited by Lukasz Szafron
submission deadline 20 Mar 2025 | 1 articles | Viewed by 928 | Submission Open
Keywords: biomarker; ovarian cancer; borderline ovarian tumor; genetic variant; epigenetics; transciptomics; proteomics; metabolomics; ovarian tumor prevention; ovarian tumor treatment
(This special issue belongs to the Section Molecular Oncology)
Periodontal Disease, Association with Systemic Conditions and Periodontal Pathogens: 2nd Edition
edited by Evangelos Papathanasiou
submission deadline 20 Mar 2025 | 1 articles | Viewed by 911 | Submission Open
Keywords: periodontal disease; periodontitis; periodontal medicine; periodontal– systemic interactions; immune response; periodontal pathogens
(This special issue belongs to the Section Molecular Immunology)
Natural Product-Based Strategy for Skin Inflammatory Disorders and Regeneration
edited by
submission deadline 20 Mar 2025 | 1 articles | Viewed by 856 | Submission Open
Keywords: inflammatory skin disorders; skin wound healing and regeneration; skin aging; bioactive natural compound; derivative and conjugate; plant extract; beneficial effect and application; molecular mechanism
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Involvement of Neuroinflammatory Processes in Psychiatric Conditions
edited by
submission deadline 20 Mar 2025 | 1 articles | Viewed by 845 | Submission Open
Keywords: neuroinflammation; glia; chemokine; cytokine; psychiatry disorder; motivation; learning; behavior; mental illness; psychopharmacology
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Research of Ocular Pathologies, 2nd Edition submission deadline 20 Mar 2025 | 1 articles | Viewed by 828 | Submission Open
Keywords: ocular pathologies; dry eye; glaucoma; retinal diseases; oxidative stress; inflammation; molecular treatments; molecular biomarkers  
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Pituitary Tumors: An Update in the Pathogenetic Mechanisms, the Diagnostic Methods and the Therapeutic Approaches
edited by
submission deadline 20 Mar 2025 | Viewed by 778 | Submission Open
Keywords: pituitary neuroendocrine tumors (PitNETs); pituitary transcription factors; PIT1; TPIT; SF1; GATA3; ERα ; pituicytoma; hypothalamic neurocytoma; hypothalamic gangliocytoma
(This special issue belongs to the Section Molecular Oncology)
Viral Infections and Immune Responses submission deadline 20 Mar 2025 | 1 articles | Viewed by 764 | Submission Open
Keywords: virus; infections; immune response; T-cells; B-cells; antibodies; neutralizing activity
(This special issue belongs to the Section Molecular Immunology)
Molecular Research of Natural Products in Cancer Diseases submission deadline 20 Mar 2025 | Viewed by 759 | Submission Open
Keywords: cancer; natural products; drug resistance; side effects; bioactive compounds; prevention; treatment; signaling pathways; tumor microenvironment
(This special issue belongs to the Section Molecular Oncology)
Characteristics of Bacteria Colonizing Animals in the Light of the "One Health" Concept
edited by
submission deadline 20 Mar 2025 | Viewed by 757 | Submission Open
Keywords: zoonotic bacteria; antimicrobial resistance; bacterial virulence traits; pathogen adaptation; whole-genome sequencing; probiotics
(This special issue belongs to the Section Molecular Microbiology)
Editorial Board Members’ Collection Series: Autoimmune Diseases—2nd Edition submission deadline 20 Mar 2025 | 1 articles | Viewed by 703 | Submission Open
Keywords: autoimmunity; autoimmune diseases; immunotherapy; biomarkers; pathogenic mechanisms
(This special issue belongs to the Section Molecular Immunology)
Gametogenesis and Age Related Changes: Cytological and Molecular Aspects submission deadline 20 Mar 2025 | Viewed by 539 | Submission Open
Keywords: aging; gametogenesis; infertility; cell metabolism; cell morphology
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms and Treatment of Migraine
edited by Noboru Imai
submission deadline 20 Mar 2025 | 1 articles | Viewed by 534 | Submission Open
Keywords: migraine; nitric oxide synthase (NOS); neuropeptides; calcitonin gene-related peptide (CGRP); pituitary adenylate cyclase activating polypeptide (PACAP); molecular pathways; therapeutic targets; neurovascular condition
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mitochondrial Medicine: Pharmacological Targeting of Mitochondria in Disease 2.0 submission deadline 20 Mar 2025 | 1 articles | Viewed by 520 | Submission Open
Keywords: cancer; complex I (NADH: ubiquinone oxidoreductase); drug toxicity; mitochondria; reactive oxygen species (ROS); therapeutic drug monitoring; cancer stem cells; cancer cell differentiation; cancer cell metabolism; cancer diagnosis; cancer therapy; complex I; oxidative phoshorylation; tumor markers; Warburg effect
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Advances in Gestational Diabetes Mellitus
edited by Natasha Singh
submission deadline 20 Mar 2025 | 1 articles | Viewed by 519 | Submission Open
Keywords: metabolome; placental insulin signaling; DNA methylation; mitochondrial oxidation; MTOR; amino acids lipidomics; proteomics; gluconeogenesis; GDM
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Gene Therapy of Inherited Diseases Using CRISPR/Cas and Other Platforms
edited by
submission deadline 20 Mar 2025 | Viewed by 485 | Submission Open
Keywords: CRISPR/Cas technology; gene therapy; adeno-associated viruses (AAVs); spinal muscular atrophy
(This special issue belongs to the Section Molecular Biology)
Topoisomerase Inhibitors: Future Perspectives and Challenges
edited by and Mark Mitton-Fry
submission deadline 20 Mar 2025 | Viewed by 460 | Submission Open
Keywords: antibiotic; topoisomerase; inhibitor; anticancer; resistance; safety
(This special issue belongs to the Section Molecular Pharmacology)
Targeted Therapy and Molecular Strategies for Gynecological Cancer submission deadline 20 Mar 2025 | Viewed by 405 | Submission Open
Keywords: gynecological cancer; targeted therapy; molecular markers; genomic profiling; immunotherapy; personalized medicine; multidisciplinary approach
(This special issue belongs to the Section Molecular Oncology)
IQSEC2 Mediated Diseases: From Mechanisms to Treatment
edited by
submission deadline 20 Mar 2025 | Viewed by 363 | Submission Open
Keywords: IQSEC2; epilepsy; autism; intellectual disability; animal model; gene therapy; pharmacogenomics
(This special issue belongs to the Section Molecular Genetics and Genomics)
Recent Research on Novel Lipid-Based Nano Drug Delivery Systems
edited by Eder Lilia Romero
submission deadline 20 Mar 2025 | Viewed by 353 | Submission Open
Keywords: lipids; nanoparticle; nanovesicle; algae; archaea; plant; bacteria; natural product
(This special issue belongs to the Section Molecular Pharmacology)
Dietary Bioactive Components in Inflammatory Bowel Disease, 2nd Edition submission deadline 20 Mar 2025 | Viewed by 345 | Submission Open
Keywords: IBD; dietary bioactive compounds; molecular mechanisms; health promotion; prevention; antioxidant; anti-inflammatory; nutritional support
(This special issue belongs to the Section Bioactives and Nutraceuticals)
New Molecular Therapeutic Approaches for Cystic Fibrosis submission deadline 20 Mar 2025 | Viewed by 335 | Submission Open
Keywords: cystic fibrosis; inflammation; 3D structures; organ-on-chip technology; organoids; endothelium; pulmonary disease; pathogens; drug resistance; miRNA; RNA interfering; CRISPR/Cas9; transfection; drug delivery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Hyperelastic Structures submission deadline 20 Mar 2025 | Viewed by 332 | Submission Open
Keywords: hyperelastic structures; biological properties; molecular properties; nonlinear elasticity; soft structures; material modeling
(This special issue belongs to the Section Materials Science)
Microbiota Dysbiosis in Parkinson’s Disease
edited by
submission deadline 20 Mar 2025 | Viewed by 329 | Submission Open
Keywords: Parkinsons’ disease; microbiome; intestinal microbiome; gut microbiome; oral microbiome; microbiota; dysbiosis; fatty acids; genetics; genomics; sequencing; 16S RNA; microbial diversity
(This special issue belongs to the Section Molecular Microbiology)
Design, Synthesis, and Bioapplications of Multifunctional Materials submission deadline 20 Mar 2025 | Viewed by 326 | Submission Open
Keywords: bioactivity; biodegradability; polymers; composite materials; (nano)structured materials; packaging; biological and biomedical materials
(This special issue belongs to the Section Materials Science)
Novel Insights into Myeloid Neoplasms: From Pathogenesis to Targeted Therapies
edited by and Chung Hoow Kok
submission deadline 20 Mar 2025 | Viewed by 325 | Submission Open
Keywords: myeloid neoplasms; pathogenesis; targeted therapies; microenvironment; immune dysregulation
(This special issue belongs to the Section Molecular Oncology)
Hormones: Evolutionary and Functional Role
edited by and Loredana Assisi
submission deadline 20 Mar 2025 | Viewed by 325 | Submission Open
Keywords: hormone action; brain organization; sexual behavior; endocrine tissue; receptor neuroexpression; endocrine control; endocrine disruption; climate change and reproduction; hormones and evolution
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advances in Telomeres and Interstitial Telomeric Sequences
edited by Anna Y Aksenova
submission deadline 20 Mar 2025 | Viewed by 320 | Submission Open
Keywords: telomeres; telomerase; interstitial telomeric sequences; alternative lengthening of telomeres; genome instability; aging; cancer
(This special issue belongs to the Section Molecular Genetics and Genomics)
CRISPR-Cas Systems and Genome Editing—2nd Edition
edited by
submission deadline 20 Mar 2025 | Viewed by 318 | Submission Open
Keywords: prokaryotic defense systems with genome editing potential (CRISPR/Cas; bacterial argonauts; etc.); development or improvement of genome editing tools; genome editing technologies in the generation and study of cellular; multicellular or animal models of hereditary; bacterial; or viral human diseases; CRISPR/Cas systems in the therapy of human diseases; genome editing to probe biotechnological processes and improve microbial producents; cultivated plants; and fungi
(This special issue belongs to the Section Molecular Genetics and Genomics)
Fiber Materials in Biomedicine: Molecular Research and Advanced Applications
edited by and Rosa Barranco-García
submission deadline 20 Mar 2025 | Viewed by 313 | Submission Open
Keywords: fibers; processing; natural; synthetic; materials; biomedicine
(This special issue belongs to the Section Materials Science)
Biological Role of Oxidative Stress in Inflammatory Diseases: 2nd Edition
edited by
submission deadline 20 Mar 2025 | Viewed by 297 | Submission Open
Keywords: oxidative stress; inflammation; endogenous antioxidant enzymes
(This special issue belongs to the Section Molecular Immunology)
Recent Advances and Insights in Treatment of Urinary Tract Diseases
edited by Cheng-Yu Long
submission deadline 20 Mar 2025 | Viewed by 291 | Submission Open
Keywords: pathophysiology of UTD; UTD treatment modality; new therapeutic approaches and its basic mechanism; medication management of UTD; estrogen deprivation and UTD; bench work of lower urinary tract dysfunction; new advances in treatment of UTD
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Yeast Modeling in Metabolism and Cell Cycle Research submission deadline 20 Mar 2025 | Viewed by 287 | Submission Open
Keywords: yeast modeling; metabolism; cell cycle development; microbial fermentation; bioactive compounds; probiotics; drug targets
(This special issue belongs to the Section Molecular Biology)
Repeat Instability, DNA Mismatch Repair and Potential for Drug Development in Repeat Expansion Disorders
edited by Marc Ciosi
submission deadline 20 Mar 2025 | Viewed by 274 | Submission Open
Keywords: repeat instability; inherited human disorders; drug delivery; DNA mismatch repair; biomarkers; unstable repeat expansions
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advancements in Perovskite and Tandem Solar Cell Technologies
edited by
submission deadline 20 Mar 2025 | Viewed by 267 | Submission Open
Keywords: perovskite solar cells; tandem photovoltaics; charge transporting materials; interfacial engineering; optoelectronic properties
(This special issue belongs to the Section Materials Science)
Advances in Terpenes: Molecular Pharmaceutics and Biotechnology
edited by Lídia Pinheiro and
submission deadline 20 Mar 2025 | Viewed by 264 | Submission Open
Keywords: terpenes; antimicrobial; anticancer; anti-inflammatory; drug discovery; drug delivery; flavours; fragrances; biofuels; biocatalysis; bioremediation
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Lipoproteins—Opportunities for the Development of Nanotherapeutics in Chronic Disease
edited by
submission deadline 20 Mar 2025 | Viewed by 263 | Submission Open
Keywords: lipoproteins; LDL; HDL; nanotherapeutics; chronic disease; targeted therapy; drug delivery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Drug Resistance Mechanisms in Human Cancer Cells to Anticancer Drugs
edited by
submission deadline 20 Mar 2025 | Viewed by 263 | Submission Open
Keywords: cancer therapy; targeted therapy; combination therapy; drug resistance; resensitization; DNA repair; DNA damage response; DNA repair inhibitors; synthetic lethality; chemoradiation
(This special issue belongs to the Section Molecular Pharmacology)
The Medicinal Mechanism and Application of Biologically Active Compounds in Melanoma
edited by Rosanna Avola and Adriana C. E. Graziano
submission deadline 20 Mar 2025 | Viewed by 245 | Submission Open
Keywords: biologically active compounds; medicinal mechanism; cancer; melanoma; chemoprevention; anticancer effect; immunomodulation; apoptosis
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Biomaterials and Tissue Regeneration in Craniofacial Defect Reconstruction
edited by and Horia Barbu
submission deadline 20 Mar 2025 | Viewed by 244 | Submission Open
Keywords: biomaterials; biocompatibility; tissue engineering; craniofacial defect; oral rehabilitation; scaffolds; regenerative medicine; angiogenesis; stem cells
(This special issue belongs to the Section Materials Science)
Inflammatory Diseases: From a Molecular Perspective
edited by Signe Holm Nielsen
submission deadline 20 Mar 2025 | Viewed by 243 | Submission Open
Keywords: inflammatory diseases; disease mechanisms; diagnosis; therapeutic targets; personalized medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Genetic, Epigenetic and Microbiota Molecular Insights for Crop Resilience to Abiotic Stress in Times of Climate Change
edited by
submission deadline 20 Mar 2025 | Viewed by 243 | Submission Open
Keywords: abiotic stress; tolerance; crop resilience; crop sustainability; environmental conditions; climate change; gene regulation; epigenetic mechanisms; microbiota communities; microbiome
(This special issue belongs to the Section Molecular Plant Sciences)
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