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Metabolites publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Lipidomics in Health and Disease

edited by

Paul Wood

submission deadline 30 Mar 2025 | 2 articles | Viewed by 2933 | Submission Open

Keywords: lipidomics; high-resolution mass spectrometry; lipid derivatization; lipid chromatography; diagnostics; therapeutics

(This special issue belongs to the Section Lipid Metabolism)

Advances in Food Sciences: Metabolomics to Unravel the Complexity of Food Metabolites

edited by

José Iván Serrano-Contreras

submission deadline 30 Mar 2025 | 1 articles | Viewed by 1294 | Submission Open

Keywords: foodomics; nutrimetabolomics; phytochemicals; food chemistry; food analysis; dark matter in diet; nutritional dark matter; nutritional hormesis; untargeted/targeted analysis

(This special issue belongs to the Section Food Metabolomics)

Exploring Potential Diagnostic and Prognostic Salivary Biomarkers in Cancer—2nd Edition

edited by

Lyudmila Bel'skaya

and

Martin Grootveld

submission deadline 31 Mar 2025 | 2 articles | Viewed by 5943 | Submission Open

Keywords: salivary biomarkers; metabolomics; salivaomics; diagnosis; prognosis; cancer

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Obesity and Metabolic Dysfunction: Disease Development and Breaking the Cycle

edited by Paulo Cezar de Freitas Mathias, Lucas Paulo Jacinto Saavedra and

Rodrigo Mello Gomes

submission deadline 31 Mar 2025 | 3 articles | Viewed by 4593 | Submission Open

Keywords: obesity; diabetes; DOHaD; metabolic programming; treatment; intervention; cardiovascular disease; metabolic syndrome

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Metabolic Biomarkers and Nutrition in Degenerative Conditions and Gastrointestinal Cancer Surgery

edited by

Irene Lidoriki

Dimitrios Schizas

and Maximos Frountzas

submission deadline 31 Mar 2025 | 2 articles | Viewed by 2561 | Submission Open

Keywords: biomarkers; nutrition; metabolism; metabolomics; degenerative disease; Parkinson’ s disease; Alzheimer’ s disease; cardiovascular disease; gastrointestinal cancer surgery

(This special issue belongs to the Section Nutrition and Metabolism)

Plant Biotic and Abiotic Stress Responses and Tolerance: Phytohormonal and Metabolic Insights

edited by

Tabibul Islam

and Md. Al Mamun

submission deadline 31 Mar 2025 | 2 articles | Viewed by 2075 | Submission Open

Keywords: biotic and abiotic stress; phytohormones: primary metabolism; secondary metabolites; plant– pathogen interactions; biostimulants; beneficial microbes; plant innate immunity; omics (genomics; transcriptomics; proteomics; metabolomics; etc.)

(This special issue belongs to the Section Plant Metabolism)

Natural Products and Dietary Supplements in Weight Loss: Metabolomic Perspectives

edited by

Eric Gumpricht

and

Alex Mohr

submission deadline 31 Mar 2025 | Viewed by 273 | Submission Open

Keywords: metabolomics; weight loss; fat loss; nutraceuticals; obesity; natural products; dietary sup-plements; phytochemicals

(This special issue belongs to the Section Integrative Metabolomics)

Proteomics and Metabolomics in Veterinary and Animal Health

edited by

Anita Horvatić

and

Andrea Gelemanović

submission deadline 31 Mar 2025 | Viewed by 246 | Submission Open

Keywords: metabolomics; proteomics; bioinformatics; omics data integration; mass spectrometry; veterinary medicine; animal health; biomarker discovery; metabolic pathways; molecular interactions

(This special issue belongs to the Section Integrative Metabolomics)

Lichen Secondary Metabolites in Cancer Research

edited by

Michal Goga

and

Martin Kello

submission deadline 31 Mar 2025 | Viewed by 139 | Submission Open

Keywords: identification of lichen substances; extraction; purification; methodology; anti-cancer effects; epigenetics; apoptosis pathways modulation; resistance mechanisms; tumor microenvironment modulation

(This special issue belongs to the Section Plant Metabolism)

Research on Lipid Metabolism in Animals

edited by

Bing Han

Lihong Zhao

and Zhenlong Wang

submission deadline 31 Mar 2025 | Viewed by 130 | Submission Open

Keywords: lipid metabolism; bile acid; gut microbiota; obesity; meat quality

(This special issue belongs to the Section Animal Metabolism)

Metabolomics Approaches to Nutrition, Intestine and Farm Animal

edited by

Shu-cheng Huang

Lihong Zhang

and Aoyun Li

submission deadline 31 Mar 2025 | Viewed by 122 | Submission Open

Keywords: farm animal; nutrition; metabolomics; metabolism; gut microbiota

(This special issue belongs to the Section Nutrition and Metabolism)

Advances in Phytomedicine Intervention on Metabolic Disorders

edited by

Hong Qin

submission deadline 31 Mar 2025 | Viewed by 122 | Submission Open

Keywords: metabolic disorders; glucose and lipid metabolism; insulin resistance; non-communicable diseases; energy imbalance; nutrients; phytochemicals; plant ac-tive components; inflammation; signaling pathway

(This special issue belongs to the Section Nutrition and Metabolism)

Advances in LC-MS-Based Metabolomics: From (Un)targeted Screening to Structural Elucidation

edited by Andrea Castellaneta and

Ilario Losito

submission deadline 31 Mar 2025 | Viewed by 119 | Submission Open

Keywords: liquid chromatography; high-resolution and multi-stage mass spectrometry; lipidomics; structure elucidation; LC-MS methods for metabolite screening; quantitative method development

(This special issue belongs to the Section Metabolomic Profiling Technology)

Metabolic Research in Animal Nutrition and Production

edited by Tietao Zhang and Qingkui Jiang

submission deadline 31 Mar 2025 | Viewed by 114 | Submission Open

Keywords: special economic animals; companion animals; nutrition; metabolomics; microbiome; metabolites; animal nutrition; animal production; animal health and disease; metabolic phenotypes

(This special issue belongs to the Section Animal Metabolism)

The Interplay Between Inflammation and Metabolism in Disease

edited by

Elena Planells

submission deadline 31 Mar 2025 | Viewed by 109 | Submission Open

Keywords: critically ill patients; micronutrients; vitamins; minerals; nutritional assessment; requirements; biomarkers; antioxidants; oxidative stress; inflammation; infection; supplementation; metabolism

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Mechanistic Insights into Metabolic Interactions with the Tumor Microenvironment

edited by

Jyoti Kaushal

submission deadline 31 Mar 2025 | Viewed by 71 | Submission Open

Keywords: metabolism; tumor microenvironment; therapy; immune cells; clinical oncology; metabolic pathways

(This special issue belongs to the Section Cell Metabolism)

The Role of Isotope Tracers in Investigating Metabolic Disorders

edited by Nadezda Khodorova

submission deadline 31 Mar 2025 | Viewed by 70 | Submission Open

Keywords: kinetics effect; isotope ratio mass spectrometry; biomarker; fluxomics; metabolomics; stable isotope; tracing experiments; mass spectrometry; breath tests

(This special issue belongs to the Section Integrative Metabolomics)

Role of Ceramides in Determining an Increased Cardiovascular and Renal Risk

edited by

Alessandro Mantovani

submission deadline 31 Mar 2025 | Viewed by 65 | Submission Open

Keywords: ceramides; cardiovascular risk; renal disease; biomarkers; sphingolipids; atherosclerosis; chronic kidney disease (CKD); cardiovascular disease (CVD); lipids

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Nutritional and Metabolic Influences on Animal Growth and Reproduction

edited by

Zhipeng Li

and

Baichuan Deng

submission deadline 31 Mar 2025 | Viewed by 64 | Submission Open

Keywords: metabolites; nutritional and metabolic influences; animal development; meat quality; dairy science; animal reproduction

(This special issue belongs to the Section Animal Metabolism)

The Digital Revolution in Livestock Production and Metabolism: Foodomics for a Viable Future and Beyond

edited by

Shuji Ueda

and

Salma Mohamad Yusop

submission deadline 31 Mar 2025 | Viewed by 41 | Submission Open

Keywords: metabolomics; foodomics; blockchain; nutritional genomics; smart farming; sustainable food production; Industry 4.0; precision livestock farming; food safety; genetic modification experiments

(This special issue belongs to the Section Food Metabolomics)

Research on Pharmacotherapy of Metabolic-Associated Fatty Liver Disease

edited by Aleksandra Bołdys

submission deadline 1 Apr 2025 | Viewed by 368 | Submission Open

Keywords: liver diseases; metabolomics; metabolic diseases; metabolic dysregulation; targeted therapies; MASLD

(This special issue belongs to the Section Pharmacology and Drug Metabolism)

New Insights on the Role of Lipid Metabolism in the Development of Cardiac Dysfunction

edited by

Stephen C. Kolwicz

submission deadline 1 Apr 2025 | Viewed by 361 | Submission Open

(This special issue belongs to the Section Lipid Metabolism)

Intestinal Health and Metabolites in Farm Animals

edited by

Qian Jiang

and Junquan Tian

submission deadline 1 Apr 2025 | Viewed by 149 | Submission Open

Keywords: metabolites; intestinal health; oxidative stress; inflammation; epithelial barrier

(This special issue belongs to the Section Animal Metabolism)

Metabolic Biomarkers in Type 2 Diabetes: From Discovery to Application

edited by Eiji Kutoh and

Shengshuai Shan

submission deadline 2 Apr 2025 | Viewed by 173 | Submission Open

Keywords: metabolic biomarkers; type 2 diabetes (T2DM); glucose metabolism; insulin resistance; lipid profiles; diagnosis and prognosis

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Metabolic Pathways of Nutrition Intake in Obese Children

edited by

Edyta Łuszczki

Katarzyna Dereń

and

Anna Bartosiewicz

submission deadline 7 Apr 2025 | Viewed by 299 | Submission Open

Keywords: children and adolescents; dietary habits; Mediterranean diet; metabolic pathways; metabolic diseases; nutrition; obesity; Western-type diet

(This special issue belongs to the Section Nutrition and Metabolism)

Metabolic Changes during Pre- and Post-harvest Fruit and Vegetable Decay, Ripening and Senescence

edited by

Analía Concellón

and

María José Zaro

submission deadline 8 Apr 2025 | 3 articles | Viewed by 3487 | Submission Open

Keywords: pre- and post-harvest technology; bio-stimulants and abiotic stress; nutritional quality; metabolic pathway; bioactive compounds; chilling injury

(This special issue belongs to the Section Plant Metabolism)

Mechanism of Metabolic Diseases

edited by

Dipsikha Biswas

and Logan Slade

submission deadline 15 Apr 2025 | Viewed by 510 | Submission Open

Keywords: metabolic diseases; nutrient signaling; metabolite profiling; genetic regulation; metabolomics; proteomics; organ crosstalk

(This special issue belongs to the Section Cell Metabolism)

Nutrition and Metabolic Changes in Aging and Age-Related Diseases

edited by Qi Zhang

submission deadline 15 Apr 2025 | Viewed by 78 | Submission Open

Keywords: senescence; metabolism; nutrient homeostasis; aging; SASP (senescence-associated secretory phenotype)

(This special issue belongs to the Section Nutrition and Metabolism)

Food Additives in Gut Microbiota and Metabolic Health

edited by Ran An, Jing Zhang and Heng Wang

submission deadline 15 Apr 2025 | Viewed by 63 | Submission Open

Keywords: food additives; emulsifier; carbohydrates; intestine; microbiota

(This special issue belongs to the Section Nutrition and Metabolism)

Energy Metabolism in Brown Adipose Tissue

edited by

Chuanhai Zhang

submission deadline 25 Apr 2025 | Viewed by 61 | Submission Open

Keywords: energy metabolism; thermogenic fat tissue; metabolites; mitochondrial function; ER stress

(This special issue belongs to the Section Cell Metabolism)

Mass Spectrometry Imaging and Spatial Metabolomics

edited by

Zhonghua Wang

and Chenglong Sun

submission deadline 28 Apr 2025 | 1 articles | Viewed by 1108 | Submission Open

Keywords: mass spectrometry imaging (MSI); spatial metabolomics; biomarker discovery; disease diagnostics; drug development; technical advancements; interdisciplinary approaches; imaging techniques

(This special issue belongs to the Section Metabolomic Profiling Technology)

Environmental Exposure and Its Effects on Cardio-Respiratory and Metabolic Health

edited by

Kristine McGrath

and Tatt Jhong Haw

submission deadline 28 Apr 2025 | Viewed by 99 | Submission Open

Keywords: environmental factors; pollution; cardiovascular; cardiometabolic risk factor; biomarkers; mechanisms; cardio-oncology; cardio-respiratory

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Metabolism and Nutrition in Fish

edited by

Lei Wang

, Peng Tan and Rantao Zuo

submission deadline 30 Apr 2025 | 2 articles | Viewed by 1911 | Submission Open

Keywords: fish; metabolism; nutrition; feed additives; lipid; protein; requirements

(This special issue belongs to the Section Animal Metabolism)

Integrative Metabolomic Biomarkers for Neurodegeneration

edited by Robert Logan

submission deadline 30 Apr 2025 | Viewed by 332 | Submission Open

Keywords: integrative metabolomics; multi-omics; biomarkers; neurodegeneration; bioinformatics; machine learning; Parkinson’ s disease; Alzheimer’ s disease

(This special issue belongs to the Section Integrative Metabolomics)

Metabolic Regulation of Reproductive Physiology in Livestock Species

edited by

Gabriele Brecchia

Giulio Curone

and Stella Agradi

submission deadline 30 Apr 2025 | Viewed by 166 | Submission Open

Keywords: metabolic regulation; reproductive physiology; livestock reproduction; energy balance; nutrient me-tabolism; fertility biomarkers; hormonal regulation; metabolic disorders; reproductive efficiency

(This special issue belongs to the Section Animal Metabolism)

New Analytical Techniques and Applications of Metabolomics and Lipidomics

edited by

Xinyu Liu

, Chunxiu Hu and Xianzhe Shi

submission deadline 30 Apr 2025 | Viewed by 151 | Submission Open

Keywords: metabolomics; lipidomics; applications of metabolomics and/or lipidomics

(This special issue belongs to the Section Advances in Metabolomics)

Enriching the Gut Microbial Functionality through Daily Meals

edited by Michihiro Fukushima and

Samanthi Pelpolage

submission deadline 30 Apr 2025 | Viewed by 136 | Submission Open

Keywords: dietary-resistant food components; intestinal fermentation; gut microbial modulation; metabolic pathways; postbiotics; food processing methods; characterization of new prebiotic substances; structure– function relationships; in vitro studies; in vivo studies; metabolic disorders

(This special issue belongs to the Section Food Metabolomics)

Mitochondrial Metabolism in Health and Disease: A Clinical Perspective

edited by

Joao Pessoa

Ana Duarte

and

Susana P. Pereira

submission deadline 30 Apr 2025 | Viewed by 129 | Submission Open

Keywords: mitochondrion; bioenergetics; oxidative stress; calcium homeostasis; apoptosis; cancer; metabolic diseases; cardiovascular diseases; neurodegenerative diseases

(This special issue belongs to the Section Cell Metabolism)

Impact of Microbial Metabolites on Intestinal Health and Diseases

edited by Ashfaqul M. Alam

submission deadline 30 Apr 2025 | Viewed by 122 | Submission Open

Keywords: gut microbiota; microbiome; metabolism; microbial metabolites; metabolomics; mass spectrometry; dysbiosis; inflammatory bowel disease; colorectal cancer; gastrointestinal tract; mucosa; epithelial barrier function; epithelial cells; inflammation; regeneration; wound healing

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

One-Carbon Metabolism in Pregnant Women, Fetuses, and Infants

edited by

Yoshinori Kubo

and

Hikaru Hori

submission deadline 30 Apr 2025 | Viewed by 102 | Submission Open

Keywords: folate cycle (5-methyltetrahydrofolate; folic acid; vitamin B12; serine; glycine); methionine cycle (homocysteine; methionine; S-adenosylmethionine; S-adenosylhomocysteine); choline metabolic pathway (betaine; choline); trans-sulfuration pathway (cysteine; taurine; vitamin B6); epigenetics; developmental origins of health and disease (DOHaD)

(This special issue belongs to the Section Nutrition and Metabolism)

Immunometabolism and Lung Fibrosis

edited by

Chao He

, Jennifer Larson-Casey and Hongli Liu

submission deadline 30 Apr 2025 | Viewed by 82 | Submission Open

Keywords: lung fibrosis; metabolism; mitochondria; fatty acid oxidation; innate immunity; adaptive immunity

(This special issue belongs to the Section Cell Metabolism)

Gut Microbiota and Nutrient Metabolism Interactions in Metabolic Syndrome and Obesity

edited by Jean Debédat and

Yen Chin Koay

submission deadline 30 Apr 2025 | Viewed by 53 | Submission Open

Keywords: microbiota; personalized medicine; nutrition; dietary intervention; xenometabolites; obesity; metabolic syndrome; diabetes; gut

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Amino Acid Metabolism and Function in Human Diseases

edited by Jolanta Bugajska and Krystyna Sztefko

submission deadline 30 Apr 2025 | Viewed by 23 | Submission Open

Keywords: free amino acids; civilization diseases; obesity; diabetes; liver disease; heart diseases; reference intervals

(This special issue belongs to the Section Cell Metabolism)

Nutritional Metabolism in Model Organisms: Phytochemicals and Genetic Responses

edited by

Carlos Lopez-Ortiz

submission deadline 30 Apr 2025 | Viewed by 20 | Submission Open

Keywords: phytochemicals; nutritional metabolism; gene expression; model organisms; genetic response; epigenetics

(This special issue belongs to the Section Nutrition and Metabolism)

Evaluation of Metabolic Changes in Mice under Chronic Toxic Substances Exposure

edited by Yun-Chung Hsiao and

Kun Lu

submission deadline 30 Apr 2025 | Viewed by 10 | Submission Open

Keywords: metabolomics; environmental contaminant; persistent organic pollutant; mass spectrometry; proteomics; toxicant; toxicological assessment; chronic toxicity; xenobiotic metabolism; lipidomic; dose– response relationship; molecular toxicology

(This special issue belongs to the Section Environmental Metabolomics)

Sex Differences in Physical Exercise and Dietary Habits Effects on Metabolic Health

edited by Hannah Cabre and

Adam M. Gonzalez

submission deadline 5 May 2025 | Viewed by 126 | Submission Open

Keywords: sex differences; metabolomics; metabolites; menstrual cycle; aging; exercise performance; nutrition intervention; cardiometabolic

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Nutritional Metabolomics in Cancer

edited by Hayato Muranaka and Suguru Saito

submission deadline 5 May 2025 | Viewed by 97 | Submission Open

Keywords: nutritional metabolomics; cancer metabolism; nutritional interventions; metabolomics in cancer therapy; cancer biomarkers

(This special issue belongs to the Section Nutrition and Metabolism)

Risk Prediction and Novel Biomarker Discovery of Chronic Diseases by Advanced Methodologies in Lipidomics and Metabolomics

edited by

Ying Zhang

, Kang Chen and Jun Ding

submission deadline 15 May 2025 | Viewed by 162 | Submission Open

Keywords: chronic diseases; lipidomics; metabolomics; risk prediction; biomarker discovery

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Advances in Gut Microbiome Metabolomics

edited by

Ulrike E. Rolle-Kampczyk

Beatrice Engelmann

and

Sven-Bastiaan Haange

submission deadline 15 May 2025 | Viewed by 103 | Submission Open

Keywords: gut microbiome– host interaction; cross talk; metabolomics; omics- technologies; microbiome signatures; new diagnostic tools; novel therapeutic strategies

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Flavonoids: Novel Therapeutic Potential for Chronic Diseases

edited by Aleksandra Kozłowska and Shawn R. Campagna

submission deadline 15 May 2025 | Viewed by 9 | Submission Open

Keywords: flavonoids; chronic diseases; inflammation; diabetes; anthocyanins; cardiovascular diseases; neurodegenerative disorders; quercetin

Displaying special issue 151-200 on page 4 of 5.

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