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Pathogens, Volume 13, Issue 6

2024 June - 92 articles

Cover Story: Verticillium wilt is a significant disease that must be managed by cotton producers around the world. Utilising reporter genes, we analyzed infections of the ascomycete fungus Verticillium dahliae in susceptible cotton hosts. We tagged Australian pathotypes that form distinct lineages of V. dahliae with either green or red fluorescent proteins to understand how it causes diseases in the field.  It was evident that the pathotypes showed in plantae characteristics of a vascular fungal pathogen and induced classic wilt symptoms in cotton plants. Using fluorescence as a marker, we also showed that common weed plant species can act as reservoirs for this pathogen, facilitating infection in subsequent cropping cycles. Our work will aid in the management of this disease in the field. View this paper
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Articles (92)

  • Review
  • Open Access
12 Citations
3,720 Views
28 Pages

Does Phage Therapy Need a Pan-Phage?

  • Petros Bozidis,
  • Eleftheria Markou,
  • Athanasia Gouni and
  • Konstantina Gartzonika

The emergence of multidrug-resistant bacteria is undoubtedly one of the most serious global health threats. One response to this threat that has been gaining momentum over the past decade is ‘phage therapy’. According to this, lytic bacte...

  • Article
  • Open Access
2,028 Views
14 Pages

Epidemiological Characterization and Genetic Variation of the SARS-CoV-2 Delta Variant in Palestine

  • Suheir Ereqat,
  • Nabil-Fareed Alikhan,
  • Amer Al-Jawabreh,
  • Michaela Matthews,
  • Ahmed Al-Jawabreh,
  • Leonardo de Oliveira Martins,
  • Alexander J. Trotter,
  • Mai Al-Kaila,
  • Andrew J. Page and
  • Abedelmajeed Nasereddin
  • + 1 author

The emergence of new SARS-CoV-2 variants in Palestine highlights the need for continuous genetic surveillance and accurate screening strategies. This case series study aimed to investigate the geographic distribution and genetic variation of the SARS...

  • Article
  • Open Access
2 Citations
2,328 Views
12 Pages

MultiTEP-Based Vaccines Targeting SARS-CoV-2 Spike Protein IgG Epitopes Elicit Robust Binding Antibody Titers with Limited Virus-Neutralizing Activity

  • Tatevik Antonyan,
  • Garri Chilingaryan,
  • Karen Zagorski,
  • Manush Ghazaryan,
  • Armine Hovakimyan,
  • Hayk Davtyan,
  • Irina Petrushina,
  • Olga King,
  • Roman Kniazev and
  • Anahit Ghochikyan
  • + 1 author

Within the last two decades, SARS-CoV-2 was the third zoonotic severe acute respiratory betacoronavirus (sarbecovirus) to infect humans, following SARS and MERS. The disruptions caused by the pandemic underscore the need for a universal vaccine again...

  • Article
  • Open Access
5 Citations
2,201 Views
14 Pages

Genetic Complexity of CC5 Staphylococcus aureus Isolates Associated with Sternal Bursitis in Chickens: Antimicrobial Resistance, Virulence, Plasmids, and Biofilm Formation

  • Vanessa Silva,
  • Jessica Ribeiro,
  • Pedro Teixeira,
  • Pedro Pinto,
  • Madalena Vieira-Pinto,
  • Patrícia Poeta,
  • Manuela Caniça and
  • Gilberto Igrejas

Sternal bursitis, a common inflammatory condition in poultry, poses significant challenges to both animal welfare and public health. This study aimed to investigate the prevalence, antimicrobial resistance, and genetic characteristics of Staphylococc...

  • Article
  • Open Access
2,073 Views
22 Pages

Evaluation of RNA Secondary Stem-Loop Structures in the UTRs of Mouse Hepatitis Virus as New Therapeutic Targets

  • Gyuhyun Kang,
  • Sun Hee Lee,
  • Miyeon Cho,
  • Ji-hyeon Kim,
  • Hyosun Cho and
  • Hyojeung Kang

MHV-A59 is a beta-coronavirus that causes demyelinating encephalitis and hepatitis in mice. Recently, the mouse infection model of MHV-A59 has been used as an alternative animal infection model for SARS-CoV and SARS-CoV-2, aiding the development of n...

  • Article
  • Open Access
1 Citations
2,333 Views
18 Pages

The Detection of Vaccine Virus and Protection of a Modified Live, Intranasal, Trivalent Vaccine in Neonatal, Colostrum-Fed Calves with an Experimental Bovine Respiratory Syncytial Virus Challenge

  • Stephanie Perkins-Oines,
  • Nirosh D. Senevirathne,
  • Greta M. Krafsur,
  • Karim Abdelsalam,
  • David Renter,
  • Brent Meyer and
  • Christopher C. L. Chase

The efficacy of an intranasal (IN) bovine respiratory syncytial virus (BRSV) vaccine administered in the presence of passive immunity was assessed. Pooled colostrum was administered by intubation to 50 beef-dairy crossbred calves the day they were bo...

  • Review
  • Open Access
12 Citations
4,176 Views
15 Pages

Genetic Diversity of Rhipicephalus (Boophilus) microplus for a Global Scenario: A Comprehensive Review

  • Muthu Sankar,
  • Binod Kumar,
  • Haranahally Vasanthachar Manjunathachar,
  • Balasamudram Chandrasekhar Parthasarathi,
  • Abhijit Nandi,
  • Chemmangat Kunnath Subramanian Neethu,
  • Gaurav Nagar and
  • Srikant Ghosh

Rhipicephalus microplus poses a substantial threat to livestock health and agricultural economies worldwide. Its remarkable adaptability to diverse environments and hosts is a testament to its extensive genetic diversity. This review delves into the...

  • Article
  • Open Access
7 Citations
2,079 Views
19 Pages

Subclinical Ovine Gammaherpesvirus 2-Related Infections in Free-Ranging Wild Boars (Sus scrofa) from Southern Brazil

  • Selwyn Arlington Headley,
  • Juliana Torres Tomazi Fritzen,
  • Flavia Helena Pereira Silva,
  • Silvio Luis Marsiglio Minarelli,
  • Leandro Meneguelli Biondo,
  • Louise Bach Kmetiuk,
  • Alexander Welker Biondo and
  • Amauri Alcindo Alfieri

Ovine gammaherpesvirus 2 (OvGHV2), is a Macavirus and the cause of sheep-associated malignant catarrhal fever (SA-MCF), in which sheep are the asymptomatic reservoir hosts. Susceptible mammalian populations infected by OvGHV2 may develop clinical SA-...

  • Article
  • Open Access
2 Citations
2,497 Views
24 Pages

Adaptive Cellular Responses following SARS-CoV-2 Vaccination in Primary Antibody Deficiency Patients

  • Sudhir Gupta,
  • Houfen Su,
  • Sudhanshu Agrawal,
  • Yesim Demirdag,
  • Michelle Tran and
  • Sastry Gollapudi

Since the start of the COVID-19 pandemic, in a short span of 3 years, vaccination against SARS-CoV-2 has resulted in the end of the pandemic. Patients with inborn errors of immunity (IEI) are at an increased risk for SARS-CoV-2 infection; however, se...

  • Editorial
  • Open Access
1 Citations
3,278 Views
5 Pages

The importance of gaining a greater understanding of the infectious diseases of wild animal populations and the impact of emerging and re-emerging pathogens has never been more sharply in focus than in the current post-COVID-19 world [...]

  • Review
  • Open Access
11 Citations
8,051 Views
57 Pages

The genus Borrelia has been divided into Borreliella spp., which can cause Lyme Disease (LD), and Borrelia spp., which can cause Relapsing Fever (RF). The distribution of genus Borrelia has broadened due to factors such as climate change, alterations...

  • Article
  • Open Access
1 Citations
2,142 Views
15 Pages

Several pathotypes of enteric E. coli have been identified. The group represented by Shiga toxin-producing E. coli (STEC) is of particular interest. Raw milk and raw milk products are significant sources of STEC infection in humans; therefore, identi...

  • Article
  • Open Access
2 Citations
3,752 Views
12 Pages

Differential Gene Expression in the Upper Respiratory Tract following Acute COVID-19 Infection in Ambulatory Patients That Develop Long COVID

  • Mia J. Biondi,
  • Mary Addo,
  • Muhammad Atif Zahoor,
  • Elsa Salvant,
  • Paul Yip,
  • Bethany Barber,
  • David Smookler,
  • Sumaiyah Wasif,
  • Kayla Gaete and
  • Robert A. Kozak
  • + 3 authors

Background: Post-acute sequelae of COVID-19, or long COVID, is a condition characterized by persistent COVID-19 symptoms. As long COVID is defined by clinical criteria after an elapsed period, an opportunity for early intervention may aid in future p...

  • Article
  • Open Access
3 Citations
1,960 Views
12 Pages

Understanding Artemisia cina Ethyl Acetate Extract’s Anthelmintic Effect on Haemonchus contortus Eggs and L3 Larvae: The Synergism of Peruvin Binary Mixtures

  • Luis David Arango-De-la Pava,
  • Manasés González-Cortazar,
  • Alejandro Zamilpa,
  • Jorge Alfredo Cuéllar-Ordaz,
  • Héctor Alejandro de la Cruz-Cruz,
  • Rosa Isabel Higuera-Piedrahita and
  • Raquel López-Arellano

Haemonchus contortus, a blood-feeding parasite in grazing sheep, causes economic losses. Drug resistance necessitates exploring plant-based anthelmintics like Artemisia cina (Asteraceae). The plant, particularly its ethyl acetate extract, shows anthe...

  • Review
  • Open Access
3 Citations
3,428 Views
11 Pages

Prior to the Food and Drug Administration approval of ledipaspavir/sofosbuvir (Harvoni®) in 2014, the treatment of hepatitis C was interferon plus or minus ribavirin. This treatment had low cure rates for hepatitis C virus and was teratogenic and...

  • Communication
  • Open Access
5 Citations
2,492 Views
6 Pages

Background: Klebsiella pneumoniae is a concerning pathogen, responsible for hospital-associated outbreaks. Multi drug resistant (MDR) strains are especially hard to treat. We conducted whole-genome sequencing on a MDR K. pneumoniae strain in order to...

  • Article
  • Open Access
1 Citations
1,827 Views
10 Pages

The Effect of Exposure to SARS-CoV-2 Vaccination and Infection on Humoral and Cellular Immunity in a Cohort of Patients with Immune-Mediated Diseases: A Pilot Study

  • Giulia Anna Maria Luigia Costanzo,
  • Giuseppina Sanna,
  • Francesco Pes,
  • Carla Maria Deiana,
  • Andrea Giovanni Ledda,
  • Andrea Perra,
  • Vanessa Palmas,
  • Valeria Manca,
  • Michela Miglianti and
  • Davide Firinu
  • + 4 authors

Immunization against COVID-19 is needed in patients with immune-mediated inflammatory diseases (IMIDs). However, data on long-term immunity kinetics remain scarce. This study aimed to compare the humoral and cellular response to COVID-19 in patients...

  • Article
  • Open Access
1 Citations
2,192 Views
14 Pages

A Simulation Study to Reveal the Epidemiology and Aerosol Transmission Characteristics of Botrytis cinerea in Grape Greenhouses

  • Lifang Yuan,
  • Hang Jiang,
  • Tinggang Li,
  • Qibao Liu,
  • Xilong Jiang,
  • Xing Han,
  • Yanfeng Wei,
  • Xiangtian Yin and
  • Suna Wang

Most previously studies had considered that plant fungal disease spread widely and quickly by airborne fungi spore. However, little is known about the release dynamics, aerodynamic diameter, and pathogenicity threshold of fungi spore in air of the gr...

  • Article
  • Open Access
1 Citations
1,585 Views
8 Pages

A Novel Cryptic Virus Isolated from Galphimia spp. in Mexico

  • Dianella Iglesias,
  • Kristian Stevens,
  • Ashutosh Sharma and
  • Alfredo Diaz-Lara

Galphimia spp. is a plant employed in traditional medicine in Mexico because of its anxiolytic and sedative effects. Viruses have been associated with different alterations in plants, although asymptomatic agents (i.e., cryptic viruses) are also know...

  • Article
  • Open Access
27 Citations
11,101 Views
15 Pages

Comprehensive Summary of Safety Data on Nirsevimab in Infants and Children from All Pivotal Randomized Clinical Trials

  • Vaishali S. Mankad,
  • Amanda Leach,
  • Yue Chang,
  • Ulrika Wählby Hamrén,
  • Alexandre Kiazand,
  • Robert J. Kubiak,
  • Therese Takas,
  • Tonya Villafana and
  • Manish Shroff

Background: Nirsevimab is approved in the US for the prevention of respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants during their first RSV season and in children aged ≤24 months who remain vulnerable to sev...

  • Article
  • Open Access
1 Citations
2,504 Views
13 Pages

Pseudomonas aeruginosa is a common pathogen associated with recreational water facilities and poses risks to public health. However, data on the prevalence of P. aeruginosa in tourist destinations like the Canary Islands, Spain, remain limited. We as...

  • Review
  • Open Access
9 Citations
6,290 Views
31 Pages

A mRNA vaccine is a type of vaccine that induces an immune response. Antigen-encoding mRNA is delivered via vaccine carriers into the immune cells, which are produced because of antigen-encoding mRNA translation, a protein. For example, COVID-19 mRNA...

  • Article
  • Open Access
2 Citations
3,686 Views
15 Pages

Cytomegalovirus, Epstein-Barr Virus, Herpes Simplex Virus, and Varicella Zoster Virus Infection Dynamics in People with Multiple Sclerosis from Northern Italy

  • Peter A. Maple,
  • Radu Tanasescu,
  • Cris S. Constantinescu,
  • Paola Valentino,
  • Marco Capobianco,
  • Silvia D’Orso,
  • Giovanna Borsellino,
  • Luca Battistini,
  • Giovanni Ristori and
  • Bruno Gran
  • + 2 authors

Previous exposure to Epstein–Barr virus (EBV) is strongly associated with the development of multiple sclerosis (MS). By contrast, past cytomegalovirus (CMV) infection may have no association, or be negatively associated with MS. This study aim...

  • Article
  • Open Access
1 Citations
2,133 Views
18 Pages

Assessing the In Vitro Individual and Combined Effect of Arthrobotrys oligospora and A. musiformis (Orbiliales) Liquid Culture Filtrates against Infective Larvae of the Sheep Blood-Feeding Nematode Haemonchus contortus (Trichostrongylidae)

  • Antonio Colinas-Picazo,
  • Pedro Mendoza-de Gives,
  • Gustavo Pérez-Anzúrez,
  • Enrique Gutiérrez-Medina,
  • Génesis Andrea Bautista-García,
  • Edgar Jesús Delgado-Núñez and
  • Agustín Olmedo-Juárez

Background: Arthrobotrys species are nematophagous fungi that secrete extracellular nematocidal products (ECP). The individual and combined effects of ECP from Arthrobotrys oligospora (Ao) and A. musiformis (Am) growth in liquid media against Haemonc...

  • Case Report
  • Open Access
1 Citations
2,021 Views
5 Pages

HIV-Negative MSM Infected with Two Different Isolates of Drug-Resistant Neisseria gonorrhoeae—Case Report

  • Martyna Biała,
  • Bartosz Pencakowski,
  • Beata Mączyńska,
  • Konrad Starzyński and
  • Bartosz Szetela

The antimicrobial resistance of Neisseria gonorrhoeae (NG) is an increasing public health concern, highlighted by the fact that gonococcus is considered as a ‘high’-priority pathogen by the WHO for research and development of new therapeu...

  • Article
  • Open Access
3 Citations
2,207 Views
17 Pages

Antiparasitic Evaluation of Aquiluscidin, a Cathelicidin Obtained from Crotalus aquilus, and the Vcn-23 Derivative Peptide against Babesia bovis, B. bigemina and B. ovata

  • Edwin Esaú Hernández-Arvizu,
  • Masahito Asada,
  • Shin-Ichiro Kawazu,
  • Carlos Agustín Vega,
  • Angelina Rodríguez-Torres,
  • Rodrigo Morales-García,
  • Aldo J. Pavón-Rocha,
  • Gloria León-Ávila,
  • Bruno Rivas-Santiago and
  • Juan Mosqueda

Babesiosis is a growing concern due to the increased prevalence of this infectious disease caused by Babesia protozoan parasites, affecting various animals and humans. With rising worries over medication side effects and emerging drug resistance, the...

  • Review
  • Open Access
1 Citations
4,191 Views
13 Pages

Nosocomial pneumonia (NP) represents a leading nosocomial infection and results in substantial morbidity and cost. Over the last several years, the evidence has evolved which directs our approach to NP. Specifically, the definition of NP and classifi...

  • Article
  • Open Access
3 Citations
3,349 Views
17 Pages

Antibiotic Resistance Profile and Bio-Control of Multidrug-Resistant Escherichia coli Isolated from Raw Milk in Vietnam Using Bacteriophages

  • Hoang Minh Duc,
  • Tran Thi Khanh Hoa,
  • Cam Thi Thu Ha,
  • Le Van Hung,
  • Nguyen Van Thang,
  • Hoang Minh Son and
  • Gary A. Flory

E. coli is an important zoonotic pathogen capable of causing foodborne illness and bovine mastitis. Bacteriophages have been increasingly considered a promising tool to control unwanted bacteria. The aim of this study is to determine the antibiotic r...

  • Article
  • Open Access
4 Citations
2,973 Views
12 Pages

Prevalence of Helminths in Small Ruminant Farms and Evaluation of Control Practices Used to Counter Anthelmintic Resistance in Southern Italy

  • Fabio Castagna,
  • Roberto Bava,
  • Marta Gagliardi,
  • Simone Russo,
  • Giusi Poerio,
  • Stefano Ruga,
  • Carmine Lupia,
  • Giuseppe Cringoli,
  • Antonio Bosco and
  • Vincenzo Musella
  • + 3 authors

Anthelmintic resistance in small ruminants is a serious worldwide problem. To reduce their spread, it is essential to know the prevalence of helminths on farms and the control practices adopted. As these studies in the Calabria region of southern Ita...

  • Article
  • Open Access
2 Citations
2,902 Views
12 Pages

Medical Causes of Hospitalisation among Patients with Bronchiectasis: A Nationwide Study in Japan

  • Akihiko Hagiwara,
  • Hisayuki Shuto,
  • Ryohei Kudoh,
  • Shota Omori,
  • Kazufumi Hiramatsu,
  • Jun-ichi Kadota,
  • Kiyohide Fushimi and
  • Kosaku Komiya

Purpose: Although the international guidelines for managing bronchiectasis are centred on preventing the exacerbation of bronchiectasis, the medical causes of admissions to hospital among patients with bronchiectasis have not been fully investigated....

  • Review
  • Open Access
9 Citations
2,998 Views
13 Pages

Effect of the COVID-19 Pandemic on Respiratory Diseases and Their Economic Impacts

  • Ananya Sivaraman Jayaraman,
  • Ishita Darekar,
  • Nidhi Vijayprakash Dadhich,
  • Lakshmi Sai Manasvi Tadepalli,
  • Yao Gongwang,
  • Sunil Singh and
  • Edem Gavor

COVID-19 is an airborne respiratory disease that mainly affects the lungs. To date, COVID-19 has infected 580 million people with a mortality of approximately 7 million people worldwide. The emergence of COVID-19 has also affected the infectivity, di...

  • Article
  • Open Access
1 Citations
2,766 Views
12 Pages

Echinococcus multilocularis and Other Intestinal Parasites of the Red Fox (Vulpes vulpes) from the Pomerania Region, Northern Poland

  • Bogumiła Pilarczyk,
  • Agnieszka Tomza-Marciniak,
  • Renata Pilarczyk,
  • Małgorzata Bąkowska,
  • Izabella Rząd,
  • Agata Stapf,
  • Lidia Felska-Błaszczyk,
  • Agnieszka Tylkowska and
  • Beata Seremak

The aim of the study was to determine the species composition of the intestinal parasite fauna of foxes from the Pomerania region, with a particular emphasis on helminth species considered dangerous to humans, and to determine their prevalence and in...

  • Article
  • Open Access
7 Citations
2,675 Views
9 Pages

Rickettsia asembonensis Isolated from Four Human Cases with Acute Undifferentiated Febrile Illness in Peru

  • Steev Loyola,
  • Rosa Palacios-Salvatierra,
  • Omar Cáceres-Rey and
  • Allen L. Richards

Rickettsioses, often underreported, pose public health challenges. Rickettsia asembonensis is a potential emerging pathogen that was previously detected in humans, animals, and a variety of arthropods. While its pathogenicity in humans remains u...

  • Article
  • Open Access
2 Citations
2,496 Views
18 Pages

Expanding Understanding of Urban Rift Valley Fever Risk and Associated Vector Ecology at Slaughterhouses in Kisumu, Kenya

  • Keli Nicole Gerken,
  • Kevin Omondi Owuor,
  • Bryson Ndenga,
  • Sammy Wambua,
  • Christabel Winter,
  • Salome Chemutai,
  • Rodney Omukuti,
  • Daniel Arabu,
  • Irene Miring’u and
  • Angelle Desiree LaBeaud
  • + 5 authors

Rift Valley fever virus (RVFV) is an adaptable arbovirus that can be transmitted by a wide variety of arthropods. Widespread urban transmission of RVFV has not yet occurred, but peri-urban outbreaks of RVFV have recently been documented in East Afric...

  • Article
  • Open Access
3 Citations
2,492 Views
14 Pages

The bacterial agent of Lyme disease, Borrelia burgdorferi, exists in an enzootic cycle by adapting to dissimilar mammalian and tick environments. The genetic elements necessary for host and vector adaptation are spread across a bacterial genome compr...

  • Brief Report
  • Open Access
4 Citations
3,033 Views
12 Pages

Detection of Human Adenovirus and Rotavirus in Wastewater in Lusaka, Zambia: Demonstrating the Utility of Environmental Surveillance for the Community

  • Ngonda Saasa,
  • Ethel M’kandawire,
  • Joseph Ndebe,
  • Mulenga Mwenda,
  • Fred Chimpukutu,
  • Andrew Nalishuwa Mukubesa,
  • Fred Njobvu,
  • Doreen Mainza Shempela,
  • Jay Sikalima and
  • Bernard M. Hang’ombe
  • + 29 authors

Enteric infections due to viral pathogens are a major public health concern. Detecting the risk areas requires a strong surveillance system for pathogenic viruses in sources such as wastewater. Towards building an environmental surveillance system in...

  • Communication
  • Open Access
2,330 Views
7 Pages

Novel Theileria sp. as an Etiology of Cutaneous Theileriosis among the Vulnerable Arabian Oryx

  • Sonia Boughattas,
  • Mutassim A. Salih,
  • Andrea Dogliero and
  • Nahla O. Eltai

The Arabian Peninsula’s endemic ungulate, Oryx leucoryx, was on the verge of extinction at the end of the 1970s. Despite the different reintroduction programs, the International Union for Conservation of Nature is still classifying it as Vulner...

  • Review
  • Open Access
6 Citations
4,169 Views
15 Pages

Parasitic Plants—Potential Vectors of Phytopathogens

  • Stefan Savov,
  • Bianka Marinova,
  • Denitsa Teofanova,
  • Martin Savov,
  • Mariela Odjakova and
  • Lyuben Zagorchev

Parasitic plants represent a peculiar group of semi- or fully heterotrophic plants, possessing the ability to extract water, minerals, and organic compounds from other plants. All parasitic plants, either root or stem, hemi- or holoparasitic, establi...

  • Article
  • Open Access
5 Citations
2,885 Views
18 Pages

First Report of Curtobacterium flaccumfaciens in Bulgaria

  • Yoana Kizheva,
  • Maria Pandova,
  • Melani Dimitrova,
  • Yoana Gladicheva,
  • Maria Garkova,
  • Desislava Pirnareva,
  • Deyan Donchev,
  • Penka Moncheva and
  • Petya Hristova

This study aims at the identification and characterization of five actinobacterial strains with presumed belonging to the species Curtobacterium flaccumfaciens isolated from tomato and pepper plants, and establishing the potential role of both plants...

  • Article
  • Open Access
4 Citations
1,893 Views
16 Pages

Peptide-Alkoxyamine Drugs: An Innovative Approach to Fight Schistosomiasis: “Digging Their Graves with Their Forks”

  • Ange W. Embo-Ibouanga,
  • Michel Nguyen,
  • Jean-Patrick Joly,
  • Mathilde Coustets,
  • Jean-Michel Augereau,
  • Lucie Paloque,
  • Nicolas Vanthuyne,
  • Raphaël Bikanga,
  • Anne Robert and
  • Sylvain R. A. Marque
  • + 4 authors

The expansion of drug resistant parasites sheds a serious concern on several neglected parasitic diseases. Our recent results on cancer led us to envision the use of peptide-alkoxyamines as a highly selective and efficient new drug against schistosom...

  • Review
  • Open Access
14 Citations
8,886 Views
19 Pages

Congenital Syphilis: A Re-Emerging but Preventable Infection

  • Serena Salomè,
  • Maria Donata Cambriglia,
  • Giovanna Montesano,
  • Letizia Capasso and
  • Francesco Raimondi

Congenital syphilis presents a significant global burden, contributing to fetal loss, stillbirth, neonatal mortality, and congenital infection. Despite the target established in 2007 by the World Health Organization (WHO) of fewer than 50 cases per 1...

  • Article
  • Open Access
3 Citations
1,813 Views
10 Pages

Catalytic Differences between Flavohemoglobins of Giardia intestinalis and E. coli

  • Sarah Hill,
  • Isabelle Decorso,
  • Novin Nezamololama,
  • Zahra Babaei and
  • Steven Patrick Rafferty

The sole known heme enzyme of the parasitic protist Giardia intestinalis is a flavohemoglobin (gFlHb) that acts as a nitric oxide dioxygenase (NOD) and protects the organism from the free radical nitric oxide. To learn more about the properties of th...

  • Article
  • Open Access
2 Citations
2,543 Views
13 Pages

Comparing Occurrence of Bovine Respiratory Pathogens Detected by High-Throughput Real-Time PCR in Nasal Swabs and Non-Endoscopic Bronchoalveolar Lavage Samples from Dairy and Veal Calves

  • Nina Dam Otten,
  • Nicole Bakkegård Goecke,
  • Anne Marie Michelsen,
  • Liza Rosenbaum Nielsen,
  • Nynne Capion,
  • Henrik Læssøe Martin,
  • Bodil Højlund Nielsen,
  • Lars Erik Larsen and
  • Mette Bisgaard Petersen

This study aimed to enhance our understanding of the agreement between two sampling methods for the detection of bovine respiratory disease (BRD) pathogens in calves using high-throughput real-time qPCR (ht-RT-qPCR). In total, 233 paired nasal swab (...

  • Article
  • Open Access
2 Citations
1,414 Views
15 Pages

Comparative Analysis of Immune Gene Transcription in Sea Bream (Sparus aurata) Challenged with RGNNV or RGNNV/SJNNV Betanodaviruses

  • Juan Gemez-Mata,
  • Patricia Moreno,
  • Daniel Alvarez-Torres,
  • Esther Garcia-Rosado,
  • Julia Bejar and
  • M. Carmen Alonso

Gilthead sea bream and European sea bass display different resistance–susceptibility patterns during infection with different nervous necrosis virus (NNV) species, which may derive from differences in the triggered immune response. Based on thi...

  • Article
  • Open Access
2 Citations
1,776 Views
12 Pages

Evaluation of the Local and Peripheral Immune Responses in Patients with Cystic Echinococcosis

  • Linda Petrone,
  • Saeid Najafi-Fard,
  • Laura Falasca,
  • Settimia Sbarra,
  • Antonella Teggi,
  • Emanuele Nicastri,
  • Lucia Rosalba Grillo,
  • Mirco Burocchi,
  • Giuseppe Maria Ettorre and
  • Delia Goletti
  • + 3 authors

Background: Cystic echinococcosis (CE) cysts may persist for decades because of immune modulation mechanisms. Here, we characterize the cysts and the blood immune responses in patients with CE. Methods: We enrolled 61 patients with CE and 19 control...

  • Article
  • Open Access
3 Citations
2,610 Views
13 Pages

The Phylogenetic Characterization of Balantioides coli Isolated in the Pavlova Culture Medium Supplemented with Coconut Water and Animal Serum

  • Camila Souza Carvalho Class,
  • Laís Lisboa Corrêa,
  • Fabiana Batalha Knackfuss,
  • Maria Regina Reis Amendoeira,
  • Francisco Ponce Gordo and
  • Alynne da Silva Barbosa

Balantioides coli is a ciliated protist that can cause dysentery in humans, pigs and nonhuman primates and may have the potential for zoonotic transmission. Its diagnosis is routinely performed through conventional parasitological techniques, and few...

  • Article
  • Open Access
3 Citations
2,260 Views
13 Pages

(1) Background: Peptides are appealing as pharmacological materials because they are easily produced, safe, and tolerable. Despite increasing gum-care awareness, periodontitis is still prevalent and is influenced by factors like high sugar consumptio...

  • Article
  • Open Access
2 Citations
2,369 Views
16 Pages

Thermophilic C. jejuni/coli is reported to be the first bacterial cause of gastroenteritis worldwide and the most common zoonosis in Europe. Although non-jejuni/coli Campylobacter sp. are increasingly suspected to be responsible for diarrhoea or to b...

  • Article
  • Open Access
3 Citations
1,827 Views
14 Pages

Evaluation of Immune Exhaustion and Co-Inhibitory Receptor Expression in Mycobacterium avium Subspecies paratuberculosis (MAP) Seropositive Diarrhoeic Bovines

  • Shalini Sharma,
  • Khushbu Sharma,
  • Ram Kumar,
  • Deen Dayal,
  • Shweta Dhanda,
  • Naveen Kumar,
  • Kundan Kumar Chaubey,
  • Shoor Vir Singh,
  • Sikander Banger and
  • Vishal Sharma

Mycobacterium avium subspecies paratuberculosis (MAP) infection leads to chronic, persistent granulomatous enteritis, causing prolonged diarrhoea and emaciation. The disease is managed using medications such as antibiotics, live vaccines, mycobacteri...

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Pathogens - ISSN 2076-0817