International Journal of Molecular Sciences

25th Anniversary of IJMS: Updates and Advances in Molecular Genetics and Genomics

edited by

Francesco Sessa

,

Lasse Lindahl

and

Apostolos Zaravinos

submission deadline 20 Jul 2026 | 15 articles | Viewed by 16390 | Submission Open

Keywords: molecular genetics; genomics; precision medicine; genetic diagnostics; gene therapy; next-generation sequencing (NGS); pharmacogenomics; epigenetics; forensic genomics; translational genomics; genome replication; gene expression; cell stress; cell cycle; cell signaling; macromolecular surveillance and turnover; molecular evolution

(This special issue belongs to the Section Molecular Genetics and Genomics)

Nanoparticles in Molecular Pharmaceutics

edited by

Qingxin Mu

submission deadline 20 Jul 2026 | 7 articles | Viewed by 15152 | Submission Open

Keywords: nanoparticles; molecular pharmaceutics; drug delivery; nanomedicine; nanoformulation

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Research for Legume Genomics, Genetics, and Breeding, 2nd Edition

edited by

Naoufal Lakhssassi

submission deadline 20 Jul 2026 | 5 articles | Viewed by 13539 | Submission Open

Keywords: legumes; genomics; plant breeding; seed composition; gene function; biotic and abiotic stress; legume pathogen resistance/mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Platelets at the Intersection of Atherosclerosis Processes

edited by

Maria Greabu

submission deadline 20 Jul 2026 | 2 articles | Viewed by 12677 | Submission Open

Keywords: platelets; inflammation; atherosclerosis; endothelial cells

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Adaptations of Plant Metabolism and Their Consequences on Nutritive Potential and Bioactivity, 2nd Edition

edited by

Ivana Sola

submission deadline 20 Jul 2026 | 2 articles | Viewed by 12561 | Submission Open

Keywords: plant primary metabolism; plant specialized metabolism; phytochemistry; plant bioactive components; plant metabolic plasticity; plant nutritional value; bioactivity of plant extracts; plant– stress response; abiotic stress; climate change; global warming; environmental pressure; biotic stress; anthropogenic influence on plant metabolites; predictive models

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Enzymes in Metabolic Processes

edited by

Koichi Fujisawa

submission deadline 20 Jul 2026 | 4 articles | Viewed by 12433 | Submission Open

Keywords: enzyme; metabolism; glycolysis; mitochondria; kinase; cell growth; carcinogenesis

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Animal Models for Human Diseases

edited by Yuning Song

submission deadline 20 Jul 2026 | 6 articles | Viewed by 12314 | Submission Open

Keywords: animal models; translational research; preclinical studies; biomedical innovation; reproducibility

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Perspective on Inflammatory Diseases: Role of Natural Compounds

edited by

Floriana D'Angeli

,

Carlo Genovese

and

Cristina Russo

submission deadline 20 Jul 2026 | 5 articles | Viewed by 12191 | Submission Open

Keywords: natural compounds; immunomodulatory activity; anti-inflammatory activity; synergistic effect; nanotechnologies; delivery systems; bioinformatic analysis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Mesenchymal Stem Cell-Based Therapy: Cell Therapy vs. EV Therapy

edited by Masahito Nakazaki

submission deadline 20 Jul 2026 | 2 articles | Viewed by 11859 | Submission Open

Keywords: mesenchymal stromal/stem cells; small extracellular vesicles; large extracellular vesicles; clinical trials; spinal cord injury; cerebrovascular disease

(This special issue belongs to the Section Biochemistry)

Recent Developments in Obesity: Metabolism, Pathophysiology and Treatment

edited by

Peteris Tretjakovs

submission deadline 20 Jul 2026 | 2 articles | Viewed by 11554 | Submission Open

Keywords: obesity; adipokines; insulin sensitivity; lipid metabolism; pro-inflammatory cytokines; gut microbiota; GLP-1 receptor agonists; personalized nutrition; lifestyle interventions

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Anticancer, Antioxidant, and Anti-Inflammatory Properties of Natural Products

edited by

Rita Carneiro Alves

,

Nelson Andrade

and Cláudia Silva

submission deadline 20 Jul 2026 | 3 articles | Viewed by 11388 | Submission Open

Keywords: bioactive compounds; natural extracts; health promotion/disease prevention; oxidative stress modulation; inflammatory pathway regulation; anticancer and antitumoral effects; cellular mechanisms; in vitro and in vivo bioactivity studies

(This special issue belongs to the Section Molecular Pharmacology)

Hypoxia: Molecular Mechanism and Health Effects

edited by

Pinar Uysal-Onganer

submission deadline 20 Jul 2026 | 6 articles | Viewed by 10850 | Submission Open

Keywords: hypoxia; inflammation; oxidative stress; metabolic conditions; hypoxia-inducible factors (HIFs); oxidative stress; mitochondrial dysfunction; angiogenesis; metabolic reprogramming; apoptosis

(This special issue belongs to the Section Molecular Biology)

Advances in Photobiomodulation Therapy

edited by Maria Fernanda Setúbal Destro Rodrigues

submission deadline 20 Jul 2026 | 4 articles | Viewed by 10813 | Submission Open

Keywords: photobiomodulation; dosimetric parameters; human diseases; modulation of inflammation; photobiomodulation therapy; molecular mechanisms; preclinical and clinical studies; therapeutic applications of PBM

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Glioblastoma Pathogenesis and Therapeutics

edited by

Claudia Desiderio

,

Giovanni Sabatino

and

Edoardo Mazzucchi

submission deadline 20 Jul 2026 | 5 articles | Viewed by 10358 | Submission Open

Keywords: glioblastoma; proteomics; immunopeptidomics; genomics; extracellular vesicles; biomarkers; molecular mechanisms; i-knife mass spectrometry; intra-operative imaging; cancer stem cells; cancer progression; neurosurgery; radiomics; personalized medicine

(This special issue belongs to the Section Molecular Oncology)

Molecular Insights into Bioactive Compounds from Agro-Industrial Waste Biomass

edited by

Ana Lima

and

Elisabete Maria de Castro Lima

submission deadline 20 Jul 2026 | 3 articles | Viewed by 10306 | Submission Open

Keywords: by-product; biocompound; bioactivity; component analysis; in vitro/in vivo experiments; circular economy; sustainability; biomass residues valorization

(This special issue belongs to the Section Biochemistry)

Molecular Insights into Placental Pathology

edited by

Mary Wallingford

and Ana Correia-Branco

submission deadline 20 Jul 2026 | 7 articles | Viewed by 9838 | Submission Open

Keywords: placenta; trophoblast; implantation; obstetrics; pre-eclampsia; placentation; maternal– fetal interface; pregnancy health; placenta diagnostics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biofunctionalization of Metals for Medical Application: Molecular Aspects

edited by

Luca Scotti

and Xiaoming Zhang

submission deadline 20 Jul 2026 | 2 articles | Viewed by 8969 | Submission Open

Keywords: biofunctionalization; medical applications; nanomaterials; nanofunctionalized materials; molecular mechanisms; bacterial membranes; membrane polarity; bacterial resistance

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Insights into Lipodystrophy

edited by

Sofía Sánchez-Iglesias

and

David Araújo-Vilar

submission deadline 20 Jul 2026 | 4 articles | Viewed by 8908 | Submission Open

Keywords: lipodystrophy; adipogenesis; animal models; lipid metabolism; therapeutic targets; insulin signaling pathways; adipose tissue

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights into the Molecular Mechanisms of the UPR and Cell Stress

edited by

Quang Duy Trinh

submission deadline 20 Jul 2026 | 6 articles | Viewed by 8880 | Submission Open

Keywords: unfolded protein response; ER stress; oxidative stress; mitochondrial dysfunction; cell stress; stress response; UPR signaling pathway; immunity; inflammation; infection

(This special issue belongs to the Section Molecular Biology)

Food-Derived Bioactive Peptides

edited by

Fidel Toldrá

and

Leticia Mora

submission deadline 20 Jul 2026 | 3 articles | Viewed by 8879 | Submission Open

Keywords: peptides identification; peptides characterization; functional foods; biological activity; peptidomics; proteomics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Insights into Hepatocellular Carcinoma: From Carcinogenesis to Liver Transplantation

edited by

Kevin Tak-Pan Ng

submission deadline 20 Jul 2026 | 5 articles | Viewed by 8170 | Submission Open

Keywords: hepatocarcinogenesis; molecular pathogenesis; tumor microenvironment; metabolic dysfunction-associated fatty liver disease (MAFLD); metastasis; genetic and epigenetic alterations; biomarkers; precision oncology; targeted therapy; immunotherapy; therapy resistance; immune escape; tumor recurrence; transplant oncology

(This special issue belongs to the Section Molecular Oncology)

Bone Metabolism and Bone Diseases

edited by

Giacomina Brunetti

submission deadline 20 Jul 2026 | 5 articles | Viewed by 8059 | Submission Open

Keywords: bone metabolism; bone diseases; osteoclast; osteoblasts and osteocytes; bone remodelling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights in the Mechanism of Obstetrical Complications: Prevention, Diagnosis, Monitoring, Treatment

edited by

Lucia Maria Procopciuc

and

Roxana Liana Lucaciu

submission deadline 20 Jul 2026 | 3 articles | Viewed by 8036 | Submission Open

Keywords: high blood pressure; gestational diabetes; infections; preeclampsia; eclampsia; preterm labor; depresion; anxiety; pregnancy loss/miscarriage; stillbirth; premature membrane rupture; vaginal bleeding; placenta previa; anemia; intrauterine growth restriction; maternal risk factors; fetal risk factors; endothelial dysfunction; angiogenesis; oxidative stress; hormonal modifications; dyslipidemia; biochemical; genetic; epigenetic determinations; computational analysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Heavy Metal Exposure on Health

edited by

Rosanna Mallamaci

submission deadline 20 Jul 2026 | 4 articles | Viewed by 7779 | Submission Open

Keywords: heavy metals; toxic metal exposure; oxidative stress; mitochondrial dysfunction; epigenetic alterations; physiological and molecular pathways of cellular toxicology; biomarkers of toxicity; chelating agents; antioxidants; therapies or treatments

(This special issue belongs to the Section Molecular Toxicology)

25th Anniversary of IJMS: Updates and Advances in Molecular Pharmacology

edited by

Roberto Scatena

submission deadline 20 Jul 2026 | 7 articles | Viewed by 7733 | Submission Open

Keywords: precision medicine; pharmacogenomics; targeted protein degradation (TPD); molecular pharmacology; RNA Therapeutics; novel drug modalities; proteomics; transcriptomics; personalized drug therapy

(This special issue belongs to the Section Molecular Pharmacology)

Advances and Emerging Trends in Marine Natural Products

edited by Rafael Alexandre Faria da Costa Félix and

Carina Félix

submission deadline 20 Jul 2026 | 5 articles | Viewed by 7480 | Submission Open

Keywords: marine natural products; bioprospecting; circular bioeconomy; bioactive compounds; antioxidant; antimicrobial; anti-inflammatory; polymers; peptides; genome mining; enzyme inhibitors; plant priming; green extraction methodologies

(This special issue belongs to the Section Molecular Pharmacology)

Physicochemical Properties and Applications of Nanomaterials in Biology and Medicine

edited by

Gangho Lee

submission deadline 20 Jul 2026 | 9 articles | Viewed by 7067 | Submission Open

Keywords: nanoparticle; nanomaterial; biomedicine; synthesis; physicochemical properties; imaging; therapy; contrast agent; therapeutic agent

(This special issue belongs to the Section Molecular Nanoscience)

HIV Infection, Pathogenesis and Treatment

edited by

Mudit Tyagi

submission deadline 20 Jul 2026 | 3 articles | Viewed by 6579 | Submission Open

Keywords: HIV Infection; HIV; host immune responses; pathogenesis

(This special issue belongs to the Section Molecular Microbiology)

Molecular Diagnosis and Treatment of Colorectal Cancer

edited by Steven T. Brower and Robert Pergolizzi

submission deadline 20 Jul 2026 | 5 articles | Viewed by 6403 | Submission Open

Keywords: colorectal cancer; biomarkers; epigenetics; targeted therapy; chemoresistance; personalized cancer therapy

(This special issue belongs to the Section Molecular Oncology)

Advances in Structural and Functional Properties of G-Quadruplexes and Aptamers

edited by

Antonella Virgilio

,

Veronica Esposito

and

Aldo Galeone

submission deadline 20 Jul 2026 | 5 articles | Viewed by 6331 | Submission Open

Keywords: G-quadruplex structure; aptamer; DNAzyme; catalytic G-quadruplexes

(This special issue belongs to the Section Molecular Biology)

Latest Molecular Advances in Autophagy

edited by

Gloria Riitano

submission deadline 20 Jul 2026 | 3 articles | Viewed by 6294 | Submission Open

Keywords: autophagy; lipid rafts; Beclin 1; autoimmune diseases; cancer; clock genes; CLOCK

(This special issue belongs to the Section Molecular Biology)

Biomolecular Structure, Function and Interactions: 2nd Edition

edited by

Ivo Crnolatac

submission deadline 20 Jul 2026 | 6 articles | Viewed by 6211 | Submission Open

Keywords: biophysical chemistry; protein– protein interactions; protein– DNA interactions; protein– ligand interactions; receptor– ligand interactions; biomolecular structure and function; protein folding and stability

(This special issue belongs to the Section Biochemistry)

Molecular Associations Between Adipose Tissue and Diseases

edited by

Roberto Cannataro

,

Erika Cione

and

Maria Cristina Caroleo

submission deadline 20 Jul 2026 | 3 articles | Viewed by 6182 | Submission Open

Keywords: lipedema; adipose tissue; adipocyte; adipose organ; body fat; miRNA; ketogenic diet

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Computational Approaches in Drug Discovery and Design: From Molecular Modeling to Translational Applications

edited by

Przemysław Czeleń

submission deadline 20 Jul 2026 | 5 articles | Viewed by 6107 | Submission Open

Keywords: computational drug discovery; molecular modeling; AI-driven drug design; molecular dynamics simulations; quantum chemistry; structure-based drug design; machine learning in pharmacology; virtual screening and docking; ADMET prediction; personalized medicine modeling

(This special issue belongs to the Section Molecular Informatics)

Innovative Strategies in Cancer Therapy

edited by

Paolo Coghi

and

Carmine Coluccini

submission deadline 20 Jul 2026 | 1 articles | Viewed by 6066 | Submission Open

Keywords: tumor microenvironment; small molecules; IDO1 inhibition; checkpoint inhibitor therapy; adoptive T cell therapy; metabolic reprogram; resistance mechanisms; immune modulation; immune reconstitution; combination therapy; immunosuppression

(This special issue belongs to the Section Molecular Oncology)

Wound Repair: From Basic Biology to Tissue Engineering

edited by

Magdalena Paczkowska-Walendowska

submission deadline 20 Jul 2026 | 3 articles | Viewed by 5993 | Submission Open

Keywords: wound healing; tissue engineering; biomaterials; regenerative medicine; chronic wounds

(This special issue belongs to the Section Molecular Biology)

Epigenetic Regulation and Molecular Mechanisms in Cardiovascular Diseases

edited by

Paschalis Karakasis

submission deadline 20 Jul 2026 | 3 articles | Viewed by 5785 | Submission Open

Keywords: epigenetic regulation; cardiovascular disease; DNA methylation; histone modifications; non-coding RNAs; vascular inflammation; myocardial remodeling; molecular mechanisms; thera-peutic targets

(This special issue belongs to the Section Molecular Genetics and Genomics)

Stroke: Novel Molecular Mechanisms and Therapeutic Approaches

edited by Kang-Ho Choi

submission deadline 20 Jul 2026 | 4 articles | Viewed by 5459 | Submission Open

Keywords: stroke; cerebrovascular disease; mechanisms; treatment; diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Supplements and Drug-Based Strategies in Neonatal and Paediatric Health

edited by

Giulia Malaguarnera

submission deadline 20 Jul 2026 | 2 articles | Viewed by 5352 | Submission Open

Keywords: neonatal pharmacology; paediatric supplements; nutraceuticals in early life; microbiota– host interactions; infectious diseases in children; neurodevelopmental disorders; drug– nutrient interactions; dosing and delivery routes; molecular paediatrics; critical analysis of paediatric interventions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Phytochemicals: Mechanisms and Applications in Cancer Prevention and Therapy

edited by

Mateusz Kciuk

and

Damian Kołat

submission deadline 20 Jul 2026 | 4 articles | Viewed by 5344 | Submission Open

Keywords: phytochemicals; cancer prevention; cancer therapy; molecular mechanisms; signal transduction pathways; anti-oxidant activity; cell death; gene regulation; therapeutic targets

(This special issue belongs to the Section Biochemistry)

Drug Delivery Systems in Veterinary Medicine: Innovations and Applications

edited by

Hualin Fu

submission deadline 20 Jul 2026 | 2 articles | Viewed by 5313 | Submission Open

Keywords: design of novel veterinary drug delivery systems; methods of preparing a veterinary drug delivery system; mechanisms of action of veterinary drug delivery systems; impact of veterinary drug delivery systems on in vivo processes of veterinary drugs; clinical evaluation of veterinary drug delivery systems

(This special issue belongs to the Section Molecular Pharmacology)

Power Up Plant Genetic Research with Genomic Data: 3rd Edition

edited by

Hon-Ming Lam

,

Sachiko Isobe

and

Man-Wah Li

submission deadline 20 Jul 2026 | 2 articles | Viewed by 5301 | Submission Open

Keywords: genome sequencing; optical mapping; genome editing; population genomics; genome-wide; association mapping; functional genomics; epigenomics; genetic interaction; chromatin; biodiversity

(This special issue belongs to the Section Molecular Genetics and Genomics)

Role of HLA (Human Leucocyte Antigen) in Human Diseases

edited by

Jeane Eliete Laguila Visentainer

submission deadline 20 Jul 2026 | 2 articles | Viewed by 5097 | Submission Open

Keywords: HLA (human leukocyte antigen); molecular immunology; autoimmune diseases; HLA genetics; antigen presentation; HLA and cancer; immunotherapy and HLA; immune responses; immunity and HLA; infectious diseases and HLA; innate and adaptive immunity; organ transplantation and HLA; HLA and immune responses; HLA genotypes and susceptibility; autoimmunity and HLA; HLA and infectious diseases; HLA and personalized therapies; molecular mechanisms of HLA; HLA mutations; experimental models of HLA; HLA and inflammation; HLA biomarkers; HLA and immunosuppression; immune tolerance and HLA; immune evasion by HLA

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biological Hallmarks and Therapeutic Strategies in Cancer

edited by Ramesh Kumar

submission deadline 20 Jul 2026 | 2 articles | Viewed by 5067 | Submission Open

Keywords: hallmarks of cancer; cancer progression; chemotherapy; tumorigenesis; oncogenic signaling

(This special issue belongs to the Section Molecular Oncology)

New Advances in Germ Cell Research

edited by

Sheng-Hsiang Li

submission deadline 20 Jul 2026 | 3 articles | Viewed by 5017 | Submission Open

Keywords: spermatogenesis; sperm capacitation; oogenesis; oocyte maturation; cumulus cells; fertilization; gene expression; biomarkers; exosomes; infertility

(This special issue belongs to the Section Molecular Biology)

Molecular Design of Artificial Receptors Using Virtual Approaches

edited by Houjin Zhang

submission deadline 20 Jul 2026 | 2 articles | Viewed by 5002 | Submission Open

Keywords: artificial receptors; protein design; computational biology; drug targeting; biosensors; tissue engineering; synthetic biology

(This special issue belongs to the Section Molecular Biophysics)

Innovative Research on Nutrition and Epigenetics in Cancer

edited by

Marisabel Mecca

submission deadline 20 Jul 2026 | 2 articles | Viewed by 4969 | Submission Open

Keywords: diet; nutrition; epigenetics; cancer; cancer therapy; lifestyle

(This special issue belongs to the Section Molecular Oncology)

Heart Failure Risk Factors and Therapies on a Molecular Basis

edited by

Tomasz Urbanowicz

submission deadline 20 Jul 2026 | 2 articles | Viewed by 4841 | Submission Open

Keywords: heart failure; risk factors; inflammatory; neutrophils; cytokines; pharmacological; therapies; molecular-based processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Pathology and Treatment of Heart Failure

edited by

Giuseppe Armentaro

submission deadline 20 Jul 2026 | 2 articles | Viewed by 4789 | Submission Open

Keywords: heart failure; oxidative stress; platelet activation; inflammation; biomarkers; pathophysiology; comorbidities

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Chronic Pain: Mechanisms and Therapeutic Innovations

edited by

Roberto Tedeschi

submission deadline 20 Jul 2026 | 2 articles | Viewed by 4715 | Submission Open

Keywords: chronic pain; pain mechanisms; pain management; therapeutic innovation; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

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