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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Research for Ovarian Cancer Biology and Therapeutics

edited by

Carmela Ricciardelli

submission deadline 20 Dec 2024 | 6 articles | Viewed by 12670 | Submission Open

Keywords: ovarian cancer; chemotherapy resistance; metastasis; novel therapetic agents; immunotherapy; CAR-T cells; cancer chemotherapy; pre-clinical models

(This special issue belongs to the Section Molecular Oncology)

Cellular Responses to Environmental Changes

edited by

Marcus Krüger

submission deadline 20 Dec 2024 | 6 articles | Viewed by 12414 | Submission Open

Keywords: environment sensing; cellular stress response; (bio)chemical environment; (bio)physical environment; mechanical environment; thermal environment; radiation; enviromics; receptors; signal transduction pathways

(This special issue belongs to the Section Molecular Biology)

Advances in Pathogenesis and Treatment of Skin Cancer

edited by

Enrica Flori

Vittoria Maresca

and

Giorgia Cardinali

submission deadline 20 Dec 2024 | 8 articles | Viewed by 12232 | Submission Open

Keywords: melanoma; squamous cell carcinoma; basal cell carcinoma; tumor microenvironment; epithelial– mesenchymal transition (EMT) process; ultraviolet radiation; oxidative stress; bioactive modulators; signal transduction pathways

(This special issue belongs to the Section Molecular Oncology)

Regeneration for Spinal Diseases 4.0

edited by

Inbo Han

Takashi Yurube

and

Daisuke Sakai

submission deadline 20 Dec 2024 | 7 articles | Viewed by 12056 | Submission Open

Keywords: regeneration; intervertebral disc degeneration; spinal cord injury; osteoporosis; spinal fusion; muscle regeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights on the Health Benefits of Vitamins, Minerals and Probiotics

edited by

Francesca Uberti

and

Claudia Penna

submission deadline 20 Dec 2024 | 3 articles | Viewed by 11143 | Submission Open

Keywords: microbiome; epigenetic alterations; molecular pathways; biomedicines; system biology; human diseases; dietary supplementation; disease prevention and treatment; gut/other tissues axes; clinical trials

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Acid–Base Metabolism, and Human Physiology and Pathophysiology

edited by

Lynda A. Frassetto

and

Thomas Remer

submission deadline 20 Dec 2024 | 6 articles | Viewed by 11097 | Submission Open

Keywords: ammoniagenesis; FGF-23-Klotho axis; growth hormone– IGF axis; hormones; kidney physiology and function; NAE; nutrition; potassium balance; PRAL; renin– angiotensin aldosterone system

(This special issue belongs to the Section Molecular Biology)

Molecular Biology of Human Fertility—2nd Edition

edited by

Antonio Simone Laganà

and

Simone Garzon

submission deadline 20 Dec 2024 | 5 articles | Viewed by 10865 | Submission Open

Keywords: infertility; gametes; embryo; implantation; placenta; endometrium; gynecological endocrinology; assisted reproduction technology; ovaries; inflammation; endometriosis

(This special issue belongs to the Section Molecular Biology)

New Advances in Type 2 Diabetes and Its Complications

edited by

Anca Pantea Stoian

submission deadline 20 Dec 2024 | 4 articles | Viewed by 10802 | Submission Open

Keywords: diabetes type 2; diabetes complications; pathophysiology of type 2 diabetes; new diabetes treatment; cardiovascular disease; stroke; peripheral artery disease; chronic kidney disease; retinopathy; neuropathy; non-alcoholic fatty liver disease in diabetes

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Olive Oil and Derivatives for Human Health

edited by

Amal Kaddoumi

submission deadline 20 Dec 2024 | 5 articles | Viewed by 10770 | Submission Open

Keywords: extra-virgin olive oil; olive oil; oleic acid; EVOO phenolics; oleocanthal; olive leaf extract; human diseases; neurodegenerative diseases; cardiovascular disease; cancer; mechanism of action

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Polyphenols and Their Impact on Human Health: 2nd Edition

edited by

Lucia Panzella

submission deadline 20 Dec 2024 | 4 articles | Viewed by 10737 | Submission Open

Keywords: polyphenols; antioxidants; food supplements; biomedical devices; skincare; agri-food by-products; sustainability

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Biomarkers in Rare Diseases 3.0

edited by

Bridget E. Bax

submission deadline 20 Dec 2024 | 5 articles | Viewed by 10395 | Submission Open

Keywords: orphan diseases; rare diseases; inborn errors of metabolism; mitochondrial disorders; biomarker discovery; biomarker panels; multiomics; endpoint measures

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Research on Plant Genomics and Genome Editing

edited by

Fabrizio Carbone

submission deadline 20 Dec 2024 | 8 articles | Viewed by 10321 | Submission Open

Keywords: next-generation sequencing; structural and functional genomics; SNPs; miRNA; LncRNA; CRISPR/Cas9; TALEN; genome editing

(This special issue belongs to the Section Molecular Plant Sciences)

Inflammation and Cancer 2023

edited by

Takuji Tanaka

Masahito Shimizu

and

Michihiro Mutoh

submission deadline 20 Dec 2024 | 6 articles | Viewed by 10159 | Submission Open

Keywords: inflammation; cytokines; gut microbiota; insulin resistance; molecular biology; autophagy; epithelial-to-mesenchymal transition (EMT); tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Microbial Omics

edited by

Nicole Hansmeier

submission deadline 20 Dec 2024 | 7 articles | Viewed by 10028 | Submission Open

Keywords: omics technologies; omics methodologies; microorganisms; proteomics; genomics; transcriptomics

(This special issue belongs to the Section Molecular Microbiology)

Latest Review Papers in Molecular Immunology 2024

edited by

Manlio Ferrarini

and

Vincenzo Barnaba

submission deadline 20 Dec 2024 | 7 articles | Viewed by 9997 | Submission Open

Keywords: molecular immunology; review; immune cells

(This special issue belongs to the Section Molecular Immunology)

Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 3.0

edited by

Menotti Ruvo

and

Annamaria Sandomenico

submission deadline 20 Dec 2024 | 6 articles | Viewed by 9858 | Submission Open

Keywords: Mabs; Fabs; ScFv; nanobodies; biomarker detection; bispecific antibodies; analyte detection; sandwich assays

(This special issue belongs to the Section Macromolecules)

Molecular Mechanisms of Plant Defense against Abiotic Stress 2.0

edited by

Emilia Apostolova

submission deadline 20 Dec 2024 | 5 articles | Viewed by 9830 | Submission Open

Keywords: abiotic stress; antioxidant activity; chlorophyll fluorescence; environmental pollution; photosynthesis; photosynthetic machinery; plant responses; plant tolerance; reactive oxygen species; thylakoid membranes; photosynthetic machinery; signal molecules

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Microglia in Neurological Disorders

edited by

Masashi Tanaka

submission deadline 20 Dec 2024 | 6 articles | Viewed by 9722 | Submission Open

Keywords: Alzheimer’ s disease; inflammation; microglia; multiple sclerosis; neurodegenerative diseases; neurological disorders; neuron; Parkinson’ s disease; phagocytosis

(This special issue belongs to the Section Molecular Neurobiology)

Brain-Body Bidirectional Communication and Its Relevance for Cerebrovascular Diseases

edited by

Aurel Popa-Wagner

submission deadline 20 Dec 2024 | 4 articles | Viewed by 9684 | Submission Open

Keywords: ischemic stroke; stroke; cerebrovascular diseases; age-associated vascular risk; aged ischemic brain

(This special issue belongs to the Section Molecular Neurobiology)

Characterization of Extracellular Vesicles in Disease

edited by

Verena Tretter

submission deadline 20 Dec 2024 | 6 articles | Viewed by 9629 | Submission Open

Keywords: extracellular vesicle; exosomes; microvesicles; vesicle cargo

(This special issue belongs to the Section Molecular Biology)

Resveratrol: Improving Human Health and Preventing Diseases

edited by

José Díaz-Chávez

submission deadline 20 Dec 2024 | 4 articles | Viewed by 9545 | Submission Open

Keywords: resveratrol supplementation; resveratrol metabolites; sirtuins; aging; epigenetic; benefits in chronic disease; treatment

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular and Structural Research Advances in Model Plants

edited by

Ioannis-Dimosthenis Adamakis

submission deadline 20 Dec 2024 | 6 articles | Viewed by 9469 | Submission Open

Keywords: A. thaliana; plant biology; model organisms; plant models; non-model plant models

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Microbiota in Immunity and Inflammation

edited by

Veronica Marrella

Barbara Cassani

and

Francesca Pala

submission deadline 20 Dec 2024 | 3 articles | Viewed by 9424 | Submission Open

Keywords: microbiota; metabolites; antimicrobial peptides; innate/adaptive immunity; inflammatory diseases; infections; cytokines

(This special issue belongs to the Section Molecular Microbiology)

New Trends in Alzheimer’s Disease Research: From Molecular Mechanisms to Therapeutics: 2nd Edition

edited by

Ramón Cacabelos

submission deadline 20 Dec 2024 | 4 articles | Viewed by 8955 | Submission Open

Keywords: Alzheimer’ s disease; pathogenic mechanisms; genomics; epigenetics; biomarkers; prevention; treatment; pharmacogenetics

(This special issue belongs to the Section Molecular Neurobiology)

Synthesis and Applications of Advanced Inorganic Materials

edited by

Taisiya Kozlova

and

Vladimir Ivanov

submission deadline 20 Dec 2024 | 5 articles | Viewed by 8850 | Submission Open

Keywords: nanomaterials; coordination compounds; metal-organic frameworks; hybrid materials; biomaterials; amorphous materials; magnetic materials; luminescent materials; ceramics

(This special issue belongs to the Section Materials Science)

Fractalkine (CX3CL1) and Its Chemoattractant and Adhesion Molecule Properties in Health and Disease

edited by

Dariusz Szukiewicz

submission deadline 20 Dec 2024 | 6 articles | Viewed by 8758 | Submission Open

Keywords: fractalkine; transmembrane fractalkine; soluble fractalkine; fractalkine receptor; CX3CL1-CX3CR1 signaling; inflammation; chemokine; cell adhesion; chemotaxis; immune response; angiogenesis; implantation; atherosclerosis; carcinogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Lung Inflammation, Injury, and Repair

edited by

Andreas Schwingshackl

submission deadline 20 Dec 2024 | 6 articles | Viewed by 8712 | Submission Open

Keywords: lung; inflammation; injury; repair; fibrosis; diagnostics; therapeutics; acute respiratory distress syndrome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Targeted Therapies of Breast Cancer

edited by

Piotr Dzięgiel

, Karolina Jabłońska and

Katarzyna Nowińska

submission deadline 20 Dec 2024 | 6 articles | Viewed by 8634 | Submission Open

Keywords: breast cancer; cancer progression; cancer metastasis; tumor microenvironment; molecular mechanisms; molecular markers; epigenetics; genomics; transcriptomics; EMT; targeted therapies; signaling pathways; exosomes; EMT; hormonal regulation; drugs; apoptosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights on Vertebrate Repetitive DNA

edited by

Maria Assunta Biscotti

Marco Barucca

and

Federica Carducci

submission deadline 20 Dec 2024 | 5 articles | Viewed by 8625 | Submission Open

Keywords: transposable elements; transposable element activity; transposable element silencing mechanisms; satellite DNA; repetitive DNA

(This special issue belongs to the Section Molecular Genetics and Genomics)

Biomaterials for Dental and Orthopedic Applications

edited by

Lia Rimondini

and

Elena Varoni

submission deadline 20 Dec 2024 | 5 articles | Viewed by 8418 | Submission Open

(This special issue belongs to the Section Materials Science)

Towards an Understanding of Retinal Diseases and Novel Treatment: 3rd Edition

edited by

Stephanie C. Joachim

submission deadline 20 Dec 2024 | 5 articles | Viewed by 8376 | Submission Open

Keywords: retina; glaucoma; age-related macular degeneration (AMD); animal model; cell culture; organ culture; molecular pathways; biomarker; neuroprotection

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Virus Infection and Infectious Diseases: Unraveling Mechanisms, Innovations, and Therapeutic Strategies

edited by Jung-Hyun Lee

submission deadline 20 Dec 2024 | 8 articles | Viewed by 8324 | Submission Open

Keywords: mechanism of virus infection; host immune responses; innovations in diagnostics and surveillance; therapeutic strategies; epidemiology and global health; data science for infectious disease; zoonotic transmission; virus evolution

(This special issue belongs to the Section Molecular Immunology)

Adipose Tissue and Gene Expression

edited by

Margherita Maffei

and

Gaia Scabia

submission deadline 20 Dec 2024 | 6 articles | Viewed by 8297 | Submission Open

Keywords: adipose tissue dysfunction; lipomatosis; fat distribution; lipodystrophy; micro-RNA; dysmetabolism; diet; inflammation; rare disease; transcription

(This special issue belongs to the Section Molecular Biology)

Neurometabolic Disorders in the Adults

edited by

Klary Niezen-Koning

and

Tom J. de Koning

submission deadline 20 Dec 2024 | 3 articles | Viewed by 8281 | Submission Open

Keywords: Neurometabolic; Metabolic/biochemical pathways; Genetic defects; Pathological phenotypes

(This special issue belongs to the Section Molecular Neurobiology)

Exploring Therapeutic Targets in the Evolving Landscape of Cancer Immunotherapy

edited by

Domenico Galati

submission deadline 20 Dec 2024 | 7 articles | Viewed by 8100 | Submission Open

Keywords: immune checkpoints; targeted therapies; tumor microenvironment; cancer immunology; precision medicine; cell-based cancer therapy

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanism in Multiple Sclerosis and Related Disorders: 2nd Edition

edited by

Hans-Peter Hartung

Giancarlo Comi

and Kazuo Fujihara

submission deadline 20 Dec 2024 | 7 articles | Viewed by 8070 | Submission Open

Keywords: neurodegeneration; multiple sclerosis; NMOSD; MOGAD; disease modifying treatments

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Endometriosis: Focusing on Molecular and Cellular Research

edited by

Alfonso Baldi

submission deadline 20 Dec 2024 | 5 articles | Viewed by 7975 | Submission Open

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Oral and Dental Infectious Diseases: Molecular Pathology, Diagnosis and Therapy

edited by

Hiromichi Yumoto

and

Keiji Murakami

submission deadline 20 Dec 2024 | 4 articles | Viewed by 7914 | Submission Open

Keywords: oral; dental; periodontitis; tooth decay; periodontal diseases; gingivitis; oral microorganism; oral infections; dental infections; dental caries; microbial pathogenicity; Porphyromonas gingivalis; antimicrobials; oral biofilm

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into the Role of Exercise in Disease and Health

edited by María José Cuevas-González and

Brisamar Estébanez

submission deadline 20 Dec 2024 | 6 articles | Viewed by 7773 | Submission Open

Keywords: physical activity; molecular mechanisms; disease prevention; metabolic health; cardiovascular diseases; neurodegenerative diseases; sarcopenia; immune function; healthy aging; epigenetics

(This special issue belongs to the Section Molecular Biology)

Diabetes and Its Complications: From Molecular Mechanisms to Novel Therapeutic Approaches

edited by

Andrea Paola Rojas Gil

submission deadline 20 Dec 2024 | 7 articles | Viewed by 7707 | Submission Open

Keywords: diabetes; diabetes complications; enviromental factors; endocrine disruptors; nutrition; sleep; therapy; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Anti-cancer Effects of Natural Products

edited by

Moon Nyeo Park

submission deadline 20 Dec 2024 | 4 articles | Viewed by 7629 | Submission Open

Keywords: cancer; natural products; herbal medicine; anticancer therapies; metastasis; recurrence; resistance mechanism; novel biomarker

(This special issue belongs to the Section Molecular Pharmacology)

Toxicity of Nanoparticles

edited by Lucyna Kapka-Skrzypczak

submission deadline 20 Dec 2024 | 5 articles | Viewed by 7598 | Submission Open

Keywords: nanoparticles; nanotoxicity; exposure to nanoparticles; health effects; biological effects; oxidative stress; environmental health

(This special issue belongs to the Section Molecular Nanoscience)

Research Progress on the Mechanism and Treatment of Cardiomyopathy

edited by

Michael T. Chin

submission deadline 20 Dec 2024 | 7 articles | Viewed by 7475 | Submission Open

Keywords: cardiomyopathy; heart failure; cardiac hypertrophy; dilated cardiomyopathy; restrictive cardiomyopathy; hypertrophic cardiomyopathy; ischemic cardiomyopathy; viral cardiomyopathy; inherited cardiomyopathy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Design, Synthesis, and Mechanism of Fluorescent and Luminescent Materials

edited by

Leire Gartzia-Rivero

and

Jorge Bañuelos Prieto

submission deadline 20 Dec 2024 | 5 articles | Viewed by 7461 | Submission Open

Keywords: luminiscent materials; molecular design and synthesis; supramolecular chemistry; emissive mechanisms and processes; photophysics; photochemistry; probes and sensors; optoelectronics

(This special issue belongs to the Section Materials Science)

Retinal Degeneration—from Genetics to Therapy: Second Edition

edited by

Nan-Kai Wang

and

Peter M.J. Quinn

submission deadline 20 Dec 2024 | 5 articles | Viewed by 7319 | Submission Open

Keywords: ophthalmology; inherited retinal dystrophies; retinal degeneration; genetics; natural history studies; gene augmentation; gene editing; reprogramming; optogenetics and splice modulation therapy; animal models; human iPSC-derived retina and retinal pigment epithelium

(This special issue belongs to the Section Molecular Biology)

Kinase Inhibitors and Kinase-Targeted Cancer Therapies

edited by

Olivier E. Pardo

submission deadline 20 Dec 2024 | 4 articles | Viewed by 7143 | Submission Open

Keywords: kinase activity inhibitors; degraders; antibodies; nanobodies; protein– kinase interaction inhibitors

(This special issue belongs to the Section Biochemistry)

The Role of NRF2 in Health and Disease

edited by

Daniela Impellizzeri

Ramona D'Amico

and

Rosalba Siracusa

submission deadline 20 Dec 2024 | 4 articles | Viewed by 7060 | Submission Open

Keywords: Nrf2; disease; inflammation; oxidative stress; therapeutics; animal models studies; in vitro studies

(This special issue belongs to the Section Biochemistry)

Bioluminescent and Fluorescent Proteins: Molecular Mechanisms and Modern Applications 4.0

edited by

Eugene S. Vysotski

submission deadline 20 Dec 2024 | 5 articles | Viewed by 6933 | Submission Open

Keywords: bioluminescence; luciferase; photoprotein; luciferin; coelenterazine; GFP; GFP-like proteins; immuno and hybridization assays; BRET and FRET assays; imaging

(This special issue belongs to the Section Molecular Biophysics)

Current Developments in Glioblastoma Research and Therapy

edited by

Aleksandra Majchrzak-Celińska

submission deadline 20 Dec 2024 | 5 articles | Viewed by 6903 | Submission Open

Keywords: diagnostic; prognostic and predictive biomarkers of glioblastoma; ways to target glioma stem cells; targeting glioblastoma-related signaling pathways; epigenetics of glioblastoma; treatment resistance mechanisms; novel treatment options for glioblastoma; combinatorial therapies; immunotherapy; nanotherapy; the application of CRISPR/Cas9 in glioma research; molecular testing of long-term glioblastoma survivors

(This special issue belongs to the Section Molecular Neurobiology)

Insights into Oral Squamous Cell Carcinoma

edited by

Emil Dediol

submission deadline 20 Dec 2024 | 4 articles | Viewed by 6900 | Submission Open

Keywords: oral cancer; tongue cancer; prognostic markers; epigenetics; molecular changes; neck metastasis; survival; miRNA; buccal cancer; screening

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 1051-1100 on page 22 of 70.

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