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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Dopamine Neurons and the Genetic Pharmacology of Addiction: Unraveling Molecular Pathways

edited by

Jolanta Chmielowiec

submission deadline 20 Apr 2025 | 1 articles | Viewed by 797 | Submission Open

Keywords: dopamine; neurons; addiction; gene; personality traits; molecular mechanisms

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms at the Intersection of Protein Synthesis, Cancer, and Immunity

edited by

Joseph Barbi

and

Sarah E. Walker

submission deadline 20 Apr 2025 | Viewed by 351 | Submission Open

Keywords: translation; protein synthesis; immunology; tumor; cancer; immune suppression; initiation; elongation; eukaryotic initiation factors; ribosome

(This special issue belongs to the Section Molecular Immunology)

The Role of microRNA in Human Diseases 3.0

edited by

Andrey Turchinovich

submission deadline 20 Apr 2025 | Viewed by 314 | Submission Open

Keywords: microRNA (miRNA); non-coding RNAs; human diseases; cancer; fatty liver; cardiovascular diseases; neurological diseases; viral infection

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Drug Discovery, Treatment, and Repurposing in Neuropsychiatric Disorders

edited by

Maria Bogdan

and

Liliana Mititelu-Tartau

submission deadline 20 Apr 2025 | Viewed by 267 | Submission Open

Keywords: animal models; neurodegeneration; neuropsychiatric disorders; neuroprotection; nanoparticles

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights into Pediatric Brain Tumors: Unraveling the Complexity of Pathogenesis and Identifying New Therapeutic Targets

edited by Xiao-Nan Li and Holly Lindsay

submission deadline 20 Apr 2025 | Viewed by 265 | Submission Open

Keywords: brain tumor; pediatric tumor biology; molecular subtyping; radiation therapy; genetic and epigenetic abnormalities; tumorigenesis investigation; targeted therapy; diagnostic markers; therapy resistance; tumor relapse

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on PRDM Genes

edited by

Erika Zazzo

Ciro Abbondanza

and

Monica Rienzo

submission deadline 20 Apr 2025 | Viewed by 231 | Submission Open

Keywords: PRDM; cancer; gene expression regulation; epigenetic modifications; proliferation; differentiation; gene expression regulation; apoptosis; cancer biomarkers; cancer diagnosis

(This special issue belongs to the Section Molecular Genetics and Genomics)

Nanocomposites and Their Biomedical Applications

edited by

Azeem Ullah

submission deadline 20 Apr 2025 | Viewed by 225 | Submission Open

Keywords: targeted drug delivery; tissue engineering; edible coatings; controlled release; wound healing; bioactive packaging; biosensing

(This special issue belongs to the Section Molecular Nanoscience)

Regulation of Ion Channels and Transporters in Related Diseases

edited by

Susumu Ohya

submission deadline 20 Apr 2025 | Viewed by 212 | Submission Open

Keywords: ion channels; ion transporters; cardiovascular disease; inflammatory disease; cancers; neurogenerative disease; disease microenvironment; drug discovery; drug resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Diabetes: From Molecular Basis to Therapy, 2nd Edition

edited by

Madalina Musat

submission deadline 20 Apr 2025 | Viewed by 79 | Submission Open

Keywords: diabetes; obesity; autoimmunity; insulin resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Abiotic Stress in Plant

edited by

Riyazuddin Riyazuddin

submission deadline 20 Apr 2025 | Viewed by 33 | Submission Open

Keywords: abiotic stress; ROS; redox; antioxidants; phytohormones; ethylene; plant stress eco-physiology

(This special issue belongs to the Section Molecular Plant Sciences)

Inhibitors of PARP to Kill Cancer Cells

edited by

Maria Raposo

submission deadline 20 Apr 2025 | Viewed by 27 | Submission Open

Keywords: DNA repair inhibitor molecules; drug delivery systems; nanoparticles; phototherapy; cancer; DNA damage

(This special issue belongs to the Section Molecular Pharmacology)

Microbiome and Metabolome in the Gastrointestinal Tract, 3rd Edition

edited by

Ioannis Alexandros Charitos

submission deadline 20 Apr 2025 | Viewed by 26 | Submission Open

Keywords: microbiome; dysbiosis; microbiology; immunity; cytokine/chemokine networks; microbiota axes pathways; toxic substances; autoimmunity

(This special issue belongs to the Section Molecular Biology)

Cancer Models: Development and Applications

edited by

Yong Teng

submission deadline 20 Apr 2025 | Viewed by 22 | Submission Open

Keywords: tumor organoids; animal models of cancer; drug screening models; highly clinically relevant cancer models; technologies related to cancer model development

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Mesenchymal Stem Cells in Organ Repair and Tissue Regeneration

edited by

Sara Cruciani

submission deadline 20 Apr 2025 | Viewed by 21 | Submission Open

Keywords: stem cells; differentiation; cell therapy; tissue regeneration; cell mechanisms; regenerative medicine; immunomodulation

(This special issue belongs to the Section Molecular Biology)

Molecular Breeding of Plants: From CRISPR/Cas9 to Transcriptomics and MABc

edited by

Kwon-Kyoo Kang

submission deadline 24 Apr 2025 | 1 articles | Viewed by 1424 | Submission Open

Keywords: CRISPR/Cas9; transcriptomics; marker-assisted breeding; genome editing; plant genetics; gene expression; plant genomics; quantitative trait loci (QTL); crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Omics Science and Research in Human Health and Disease

edited by Elisa De Paolis

submission deadline 25 Apr 2025 | Viewed by 128 | Submission Open

Keywords: genomics; transcriptomics; proteomics; metabolomics; single-cell analysis; spatial transcriptomics; bioinformatics; multi-omics

(This special issue belongs to the Section Molecular Biology)

Molecular and Cellular Mechanisms of Spinal Cord Injury and Repair

edited by Victoria Moreno-Manzano

submission deadline 25 Apr 2025 | Viewed by 110 | Submission Open

Keywords: spinal cord injury; molecular changes; neuronal degeneration; circuit regeneration; transcriptomics; cell imaging; single-cell analysis; cell communication; behavior; functional outputs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic Testing in Molecular Pathology and Diagnosis

edited by

Marco Fabiani

submission deadline 25 Apr 2025 | Viewed by 72 | Submission Open

Keywords: genetic testing; molecular pathology; personalized medicine; genetic diagnostics; disease mechanisms; novel genetic tests; clinical integration; patient management

(This special issue belongs to the Section Molecular Biology)

Effects of Ionizing Radiation in Cancer Radiotherapy: 2nd Edition

edited by

François Chevalier

submission deadline 25 Apr 2025 | Viewed by 51 | Submission Open

Keywords: non-targeted effects; radiation-induced bystander effect; abscopal effect; genomic instability; low dose effects; radioprotection; circulating biomarkers; oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Cardiac Disease

edited by

Daniela Rossin

submission deadline 29 Apr 2025 | Viewed by 12 | Submission Open

Keywords: innovative cardiac research; multidisciplinary cardiovascular approaches; advances in cardio-vascular diagnosis; novel cardiac therapies; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mitochondrial Function in Health and Disease, 3rd Edition

edited by

Galina D. Mironova

and

Natalia Belosludtseva

submission deadline 30 Apr 2025 | 7 articles | Viewed by 15802 | Submission Open

Keywords: mitochondrial function; ultrastructural alterations; oxidative phosphorylation; mitochondrial ion channels; mitochondrial permeability transition pores; mitochondrial defensive antioxidant systems; oxidative stress; mitophagy; apoptosis; mitochondria-targeted therapeutic strategies; antioxidant therapy

(This special issue belongs to the Section Biochemistry)

Raman Spectroscopy and Machine Learning in Human Disease

edited by

Ivan Bratchenko

submission deadline 30 Apr 2025 | 7 articles | Viewed by 12680 | Submission Open

Keywords: Raman spectroscopy; machine learning; disease; molecular diagnostics; optical biopsy; liquid biopsy

(This special issue belongs to the Section Molecular Biophysics)

Cellular and Molecular Progression of Cardiovascular Diseases

edited by

Andrea Borghini

Antonio Rizza

and

Alessandro Tonacci

submission deadline 30 Apr 2025 | 3 articles | Viewed by 3876 | Submission Open

Keywords: cardiovascular diseases; multi-omics data; biomarkers; molecular level; pathophysiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Bioactives and Inflammation, 2nd Edition

edited by

Juan Gambini

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1515 | Submission Open

Keywords: inflammation; bioactive compounds; polyphenols; nutraceutical; diet; nutrition; pharmacology; health; lifespan; healthspan; aging; inflammaging

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Metal Toxicity in Animals: Recent Insights on Physiological and Molecular Aspects

edited by

Rosaria Scudiero

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1330 | Submission Open

Keywords: heavy metals; lanthanides; physiological and molecular pathways of cellular toxicology; environmental pollution; risk assessments; risk of mixing contaminants

(This special issue belongs to the Section Molecular Toxicology)

Oxidative Stress and Inflammation in the Tissue Repair—Pathways and Biotechnologies

edited by Reggiani Vilela Gonçalves and Rômulo Dias Novaes

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1162 | Submission Open

Keywords: oxidative stress; inflammasome; cytokines; angiogenesis; remodeling; molecular pathways; apoptotic alterations; diabetes; tissue repair

(This special issue belongs to the Section Biochemistry)

Unraveling Apoptosis: Deciphering Molecular Mechanisms

edited by

Gabriella Simbula

submission deadline 30 Apr 2025 | Viewed by 353 | Submission Open

Keywords: apoptosis; development; microenvironment; mitochondria dysfunction; molecular mechanisms; tumors; degenerative diseases; diabetes; metabolic diseases; neurodegenerative disease; novel pharmacological strategies

(This special issue belongs to the Section Biochemistry)

Molecular and Cellular Mechanisms in Cardiomyopathy

edited by

Susan Currie

and Niall MacQuaide

submission deadline 30 Apr 2025 | Viewed by 139 | Submission Open

Keywords: E-C coupling; cardiac myocyte; cardiac fibroblast; ryanodine receptor; SERCA2a; CaMKII; phosphodiesterase

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances of Free-Radical Reactions in Organic Chemistry

edited by

José Justicia

submission deadline 30 Apr 2025 | Viewed by 101 | Submission Open

Keywords: free-radical reactions; organic chemistry; organic synthesis; fotoredox reactions; organometallics reactions; computational calculations; free radicals in biology; free radicals in green chemistry

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Pharmacology and Toxicology of Synthetic and Natural Products

edited by

Sherif T. S. Hassan

submission deadline 30 Apr 2025 | Viewed by 87 | Submission Open

Keywords: pharmacology and toxicology; pharmacodynamics and pharmacokinetics; synthetic drugs; natural products; drug interactions; molecular mechanisms; therapeutic potential; adverse effects; dose– response relationship; drug safety and efficacy

(This special issue belongs to the Section Molecular Pharmacology)

Heart Failure Risk Factors and Therapies-Molecular Basis

edited by

Tomasz Urbanowicz

submission deadline 30 Apr 2025 | Viewed by 41 | Submission Open

Keywords: heart failure; risk factors; inflammatory; neutrophils; cytokines; pharmacological; therapies; molecular-based processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Emerging Role of Quantum Sciences and Radiation Biology in Biomedical Applications, 2nd Edition

edited by

Nikolaj Sorgenfrei Blom

and

Livio Giuliani

submission deadline 30 Apr 2025 | Viewed by 35 | Submission Open

Keywords: quantum sciences; radiation biology; biomedical applications

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Emerging Trends of Quantum Mechanics, Computational Chemistry, and Spectroscopy in Physical Chemistry

edited by

Dongho Kim

submission deadline 30 Apr 2025 | Viewed by 35 | Submission Open

Keywords: quantum theory; computational chemistry; spectroscopy

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

New Perspectives on Prostate Cancer Occurrence, Diagnosis, and Treatment

edited by

Michele Marchioni

and

Luigi Schips

submission deadline 30 Apr 2025 | Viewed by 32 | Submission Open

Keywords: prostate cancer; biomarker; diagnosis; treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Studies in Aging, 2nd Edition

edited by

Rosa Mancinelli

submission deadline 30 Apr 2025 | Viewed by 22 | Submission Open

Keywords: senescence; active aging; sarcopenia; osteoporosis; oxidative stress; brain aging; cardiovascular aging

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Structures, Syntheses of Natural Products, and Their Biological Effects

edited by

Ran Jia

submission deadline 30 Apr 2025 | Viewed by 21 | Submission Open

Keywords: structures of natural products; syntheses; biological effects; biomedical applications

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Bile Acids and Bile Acid Modifications in Health and Disease

edited by

Francisco J. Osuna-Prieto

submission deadline 30 Apr 2025 | Viewed by 17 | Submission Open

Keywords: bile acids; bile acid modifications; bile acid signaling; bile acid metabolism; metabolic disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Tumor Angiogenesis and Metastasis: From Molecular Signalling to Therapeutic Approaches

edited by

Federica Finetti

and

Lorenza Trabalzini

submission deadline 30 Apr 2025 | Viewed by 13 | Submission Open

Keywords: tumour angiogenesis; tumour invasion; tumour metastasis; molecular mechanisms; metabolic patterns; signalling pathways

(This special issue belongs to the Section Molecular Oncology)

Chemical and Biotechnological Strategies to Tailor the Properties of Biomaterials

edited by

Eduardo García-Junceda

and

Julia Revuelta

submission deadline 30 Apr 2025 | Viewed by 5 | Submission Open

Keywords: biomaterial functionalization; green chemistry in biomaterials; biotechnological modification; stimuli-responsive materials; translational biomaterials

(This special issue belongs to the Section Materials Science)

Molecular Mechanism in Cardiovascular Pathology

edited by Andrea Marzullo

submission deadline 30 Apr 2025 | Viewed by 2 | Submission Open

Keywords: cardiovascular diseases; molecular biology; sudden death; cardiomyopathies; heart failure; coronary artery diseases; pericarditis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances and Perspectives of Lung Disease: 2nd Edition

edited by

Longshuang Huang

submission deadline 30 Apr 2025 | Viewed by 2 | Submission Open

Keywords: lung disease; inflammation; regeneration; infection; drug discovery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Mitochondrial Genetics and Epigenetics

edited by Arianna Montanari

submission deadline 30 Apr 2025 | Submission Open

Keywords: mitochondrial DNA dynamics; retrograde regulation; epigenetic modulators; mitochondrial diseases; cellular homeostasis

(This special issue belongs to the Section Molecular Biology)

Molecular Research for Cereal Grain Quality 2.0

edited by

Jinsong Bao

submission deadline 10 May 2025 | 6 articles | Viewed by 9950 | Submission Open

Keywords: cereal; rice; wheat; maize; barley; sorghum; millet; molecular markers; genome-wide association studies; genome editing; genome selection; sequencing; molecular selection; transcriptomics; omics; post-translational regulation; starch; protein; lipids; vitamin; phenolics; processing quality; eating quality

(This special issue belongs to the Section Molecular Plant Sciences)

Hematological Malignancies: Molecular Mechanisms and Therapy, 2nd Edition

edited by

Stella Bouziana

submission deadline 15 May 2025 | Viewed by 4 | Submission Open

Keywords: hematological malignancies; molecular pathways; genetics; immunopathogenesis; biomarkers; novel therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Pharmacological Insights on Natural Macromolecules and Natural Small Molecules

edited by

Dong-Sung Lee

submission deadline 20 May 2025 | 7 articles | Viewed by 14837 | Submission Open

Keywords: bioactive natural molecules; natural macromolecules; natural small molecules; drug delivery; inflammatoty diseases; neurodegenerative diseases; skin diseases; cancer; metabolic diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Blast-Induced Neurotrauma: Molecular Mechanisms Supported by Comparative Experimental and Clinical Findings

edited by

Ibolja Cernak

submission deadline 20 May 2025 | 6 articles | Viewed by 13231 | Submission Open

Keywords: blast injuries; blast-induced neurotrauma; experimental research; experimental models; clinical research; molecular mechanisms; biomarkers; imaging; neurological deficits; treatment

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Liver Fibrosis

edited by

Domenica Mangieri

submission deadline 20 May 2025 | 4 articles | Viewed by 6608 | Submission Open

Keywords: liver fibrosis; inflammation; hypoxia; angiogenesis; hepatic stellate cells; drug therapy; natural compounds; phytochemicals

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Drugs Regulating Cytoskeletons in Human Health and Diseases

edited by

Gilles Breuzard

Maxime Robin

and

Hervé Kovacic

submission deadline 20 May 2025 | 4 articles | Viewed by 5698 | Submission Open

Keywords: tubulin; actine; cytoskeletons; associated proteins; pharmacological agent; repurposing of drugs; oncology; neurodegenerative diseases

(This special issue belongs to the Section Molecular Pharmacology)

Current Uses and Applications of Cyclodextrins

edited by

Zoltan Juvancz

and

Cecilia Cagliero

submission deadline 20 May 2025 | 4 articles | Viewed by 5297 | Submission Open

Keywords: cyclodextrins; chiral separations; GC; HPLC; SFC; and CE; chiral recognition mechanisms; structure– chiral selectivity relationships; a combination of chromatographic and structure determination methods (e.g.; MS; NMR; CD; etc.)

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Innovations in Polymeric Materials: Exploring Advancements and Applications

edited by

Silvia Vasiliu

submission deadline 20 May 2025 | 2 articles | Viewed by 2611 | Submission Open

Keywords: eco-friendly polymers; nanocomposites; biodegradable polymers; smart materials; polymer recycling; drug delivery systems; biocompatible polymers; food industry; wastewater treatment

(This special issue belongs to the Section Materials Science)

Displaying special issue 3401-3450 on page 69 of 70.

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